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Volumn 6, Issue , 2013, Pages 123-129

Gender difference in response predictors after 1-year exenatide therapy twice daily in type 2 diabetic patients: A real world experience

Author keywords

Exenatide BID; GLP 1 agonist therapy; Real world setting; Type 2 diabetes

Indexed keywords

EXENDIN 4; GLUCOSE; HEMOGLOBIN A1C; METFORMIN; SULFONYLUREA;

EID: 84876054019     PISSN: 11787007     EISSN: None     Source Type: Journal    
DOI: 10.2147/DMSO.S42729     Document Type: Article
Times cited : (51)

References (31)
  • 1
    • 0030034518 scopus 로고    scopus 로고
    • United Kingdom Prospective Diabetes Study 17: A 9-year update of a randomized, controlled trial on the effect of improved metabolic control on complications in non-insulin-dependent diabetes mellitus
    • Turner R, Cull C, Holman R. United Kingdom Prospective Diabetes Study 17: a 9-year update of a randomized, controlled trial on the effect of improved metabolic control on complications in non-insulin-dependent diabetes mellitus. Ann Intern Med. 1996;124(1 Pt 2):136-145.
    • (1996) Ann Intern Med , vol.124 , Issue.1 PT. 2 , pp. 136-145
    • Turner, R.1    Cull, C.2    Holman, R.3
  • 2
    • 33745661675 scopus 로고    scopus 로고
    • Glycemic control and macrovascular disease in types 1 and 2 diabetes mellitus: Meta-analysis of randomized trials
    • Stettler C, Allemann S, Jüni P, et al. Glycemic control and macrovascular disease in types 1 and 2 diabetes mellitus: Meta-analysis of randomized trials. Am Heart J. 2006;152(1):27-38.
    • (2006) Am Heart J , vol.152 , Issue.1 , pp. 27-38
    • Stettler, C.1    Allemann, S.2    Jüni, P.3
  • 3
    • 43449100355 scopus 로고    scopus 로고
    • Hypoglycaemic symptoms, treatment satisfaction, adherence and their associations with glycaemic goal in patients with type 2 diabetes mellitus: Findings from the Real-Life Effectiveness and Care Patterns of Diabetes Management (RECAP-DM) Study
    • Alvarez Guisasola F, Tofé Povedano S, Krishnarajah G, Lyu R, Mavros P, Yin D. Hypoglycaemic symptoms, treatment satisfaction, adherence and their associations with glycaemic goal in patients with type 2 diabetes mellitus: findings from the Real-Life Effectiveness and Care Patterns of Diabetes Management (RECAP-DM) Study. Diabetes Obes Metab. 2008;10 Suppl 1:25-32.
    • (2008) Diabetes Obes Metab , vol.10 , Issue.1 SUPPL. , pp. 25-32
    • Alvarez, G.F.1    Tofé, P.S.2    Krishnarajah, G.3    Lyu, R.4    Mavros, P.5    Yin, D.6
  • 4
    • 35848950954 scopus 로고    scopus 로고
    • High frequency of unrecognized hypoglycaemias in patients with type 2 diabetes is discovered by continuous glucose monitoring
    • Weber KK, Lohmann T, Busch K, Donati-Hirsch I, Riel R. High frequency of unrecognized hypoglycaemias in patients with type 2 diabetes is discovered by continuous glucose monitoring. Exp Clin Endocrinol Diabetes. 2007;115(8):491-494.
    • (2007) Exp Clin Endocrinol Diabetes , vol.115 , Issue.8 , pp. 491-494
    • Weber, K.K.1    Lohmann, T.2    Busch, K.3    Donati-Hirsch, I.4    Riel, R.5
  • 5
    • 84866268783 scopus 로고    scopus 로고
    • Management of hyperglycemia in type 2 diabetes: A patient-centered approach: Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
    • for American Diabetes Association (ADA), European Association for the Study of Diabetes (EASD)
    • Inzucchi SE, Bergenstal RM, Buse JB, et al; for American Diabetes Association (ADA), European Association for the Study of Diabetes (EASD). Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2012;35(6):1364-1379.
    • (2012) Diabetes Care , vol.35 , Issue.6 , pp. 1364-1379
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3
  • 6
    • 36749042536 scopus 로고    scopus 로고
    • GLP-1-based therapy of type 2 diabetes: GLP-1 mimetics and DPP-IV inhibitors
    • Ahrén B. GLP-1-based therapy of type 2 diabetes: GLP-1 mimetics and DPP-IV inhibitors. Curr Diab Rep. 2007;7(5):340-347.
    • (2007) Curr Diab Rep , vol.7 , Issue.5 , pp. 340-347
    • Ahrén, B.1
  • 7
    • 45749095401 scopus 로고    scopus 로고
    • Incretin mimetics and dipeptidyl peptidase 4 inhibitors in clinical trials for the treatment of type 2 diabetes
    • Mikhail N. Incretin mimetics and dipeptidyl peptidase 4 inhibitors in clinical trials for the treatment of type 2 diabetes. Expert Opin Investig Drugs. 2008;17(6):845-853.
    • (2008) Expert Opin Investig Drugs , vol.17 , Issue.6 , pp. 845-853
    • Mikhail, N.1
  • 8
    • 84864653850 scopus 로고    scopus 로고
    • Exenatide extended-release: A review of its use in type 2 diabetes mellitus
    • Scott LJ. Exenatide extended-release: a review of its use in type 2 diabetes mellitus. Drugs. 2012;72(12):1679-1707.
    • (2012) Drugs , vol.72 , Issue.12 , pp. 1679-1707
    • Scott, L.J.1
  • 9
    • 0345374580 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets
    • Farilla L, Bulotta A, Hirshberg B, et al. Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets. Endocrinology. 2003;144(12):5149-5158.
    • (2003) Endocrinology , vol.144 , Issue.12 , pp. 5149-5158
    • Farilla, L.1    Bulotta, A.2    Hirshberg, B.3
  • 10
    • 0037414781 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis
    • Li YZ, Hansotia T, Yusta B, Ris F, Halban PA, Drucker DJ. Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis. J Biol Chem. 2003;278(1):471-478.
    • (2003) J Biol Chem , vol.278 , Issue.1 , pp. 471-478
    • Li, Y.Z.1    Hansotia, T.2    Yusta, B.3    Ris, F.4    Halban, P.A.5    Drucker, D.J.6
  • 11
    • 0032005005 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
    • Flint A, Raben A, Astrup A, Holst JJ. Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest. 1998; 101(3):515-520.
    • (1998) J Clin Invest , vol.101 , Issue.3 , pp. 515-520
    • Flint, A.1    Raben, A.2    Astrup, A.3    Holst, J.J.4
  • 12
    • 4344667831 scopus 로고    scopus 로고
    • A recombinant human glucagon-like peptide (GLP)-1-albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis
    • Baggio LL, Huang Q, Brown TJ, Drucker DJ. A recombinant human glucagon-like peptide (GLP)-1-albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis. Diabetes. 2004;53(9):2492-2500.
    • (2004) Diabetes , vol.53 , Issue.9 , pp. 2492-2500
    • Baggio, L.L.1    Huang, Q.2    Brown, T.J.3    Drucker, D.J.4
  • 13
    • 0027248866 scopus 로고
    • Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients
    • Nauck MA, Kleine N, Orskov C, Holst JJ, Willms B, Creutzfeldt W. Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. Diabetologia. 1993;36(8):741-744.
    • (1993) Diabetologia , vol.36 , Issue.8 , pp. 741-744
    • Nauck, M.A.1    Kleine, N.2    Orskov, C.3    Holst, J.J.4    Willms, B.5    Creutzfeldt, W.6
  • 14
    • 34447267513 scopus 로고    scopus 로고
    • Efficacy and safety of incretin therapy in type 2 diabetes: Systematic review and meta-analysis
    • Amori RE, Lau J, Pittas AG. Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis. JAMA. 2007;298(2):194-206.
    • (2007) JAMA , vol.298 , Issue.2 , pp. 194-206
    • Amori, R.E.1    Lau, J.2    Pittas, A.G.3
  • 15
    • 60349099802 scopus 로고    scopus 로고
    • New treatments in type 2 diabetes: A focus on the incretin-based therapies
    • Barnett AH. New treatments in type 2 diabetes: a focus on the incretin-based therapies. Clin Endocrinol (Oxf). 2009;70(3):343-353.
    • (2009) Clin Endocrinol (Oxf) , vol.70 , Issue.3 , pp. 343-353
    • Barnett, A.H.1
  • 16
    • 66149108722 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor agonists in type 2 diabetes: A meta-analysis of randomized clinical trials
    • Monami M, Marchionni N, Mannucci E. Glucagon-like peptide-1 receptor agonists in type 2 diabetes: a meta-analysis of randomized clinical trials. Eur J Endocrinol. 2009;160(6):909-917.
    • (2009) Eur J Endocrinol , vol.160 , Issue.6 , pp. 909-917
    • Monami, M.1    Marchionni, N.2    Mannucci, E.3
  • 17
    • 69249195769 scopus 로고    scopus 로고
    • Exenatide efficacy and safety: A systematic review
    • Norris SL, Lee N, Thakurta S, Chan BK. Exenatide efficacy and safety: a systematic review. Diabet Med. 2009;26(9):837-846.
    • (2009) Diabet Med , vol.26 , Issue.9 , pp. 837-846
    • Norris, S.L.1    Lee, N.2    Thakurta, S.3    Chan, B.K.4
  • 18
    • 78649800940 scopus 로고    scopus 로고
    • Glucagon-like peptide analogues for type 2 diabetes mellitus: Systematic review and meta-analysis
    • Shyangdan DS, Royle PL, Clar C, Sharma P, Waugh NR. Glucagon-like peptide analogues for type 2 diabetes mellitus: systematic review and meta-analysis. BMC Endocr Disord. 2010;10:20.
    • (2010) BMC Endocr Disord , vol.10 , pp. 20
    • Shyangdan, D.S.1    Royle, P.L.2    Clar, C.3    Sharma, P.4    Waugh, N.R.5
  • 19
    • 84876062450 scopus 로고    scopus 로고
    • NHS National Institute for Health and Clinical Excellence, London, UK: NHS National Institute for Health and Clinical Excellence, Available from, Accessed March 25, 2013
    • NHS National Institute for Health and Clinical Excellence. Clinical guidelines CG87: Type 2 diabetes - newer agents (partial CG66) (CG87) [homepage on the Internet]. London, UK: NHS National Institute for Health and Clinical Excellence; 2009. Available from: http://www.nice. org.uk/cg87. Accessed March 25, 2013.
    • (2009) Clinical Guidelines CG87: Type 2 Diabetes - Newer Agents (partial CG66) (CG87) [homepage On the Internet]
  • 20
    • 78649447003 scopus 로고    scopus 로고
    • One-year metabolic out-comes in patients with type 2 diabetes treated with exenatide in routine practice
    • Buysschaert M, Preumont V, Oriot PR, et al. One-year metabolic out-comes in patients with type 2 diabetes treated with exenatide in routine practice. Diabetes Metab. 2010;36(5):381-388.
    • (2010) Diabetes Metab , vol.36 , Issue.5 , pp. 381-388
    • Buysschaert, M.1    Preumont, V.2    Oriot, P.R.3
  • 21
    • 81855221189 scopus 로고    scopus 로고
    • Exenatide BID Observational Study (ExOS): Results for primary and secondary endpoints of a prospective research study to evaluate the clinical effectiveness of exenatide BID use in patients with type 2 diabetes in a real-world setting
    • Bergenstal RM, Garrison LP Jr, Miller LA, et al. Exenatide BID Observational Study (ExOS): results for primary and secondary endpoints of a prospective research study to evaluate the clinical effectiveness of exenatide BID use in patients with type 2 diabetes in a real-world setting. Curr Med Res Opin. 2011;27(12):2335-2342.
    • (2011) Curr Med Res Opin , vol.27 , Issue.12 , pp. 2335-2342
    • Bergenstal, R.M.1    Garrison Jr., L.P.2    Miller, L.A.3
  • 22
    • 15944366927 scopus 로고    scopus 로고
    • Nutrient-stimulated GLP-1 release in normal-weight men and women
    • Adam TC, Westerterp-Plantenga MS. Nutrient-stimulated GLP-1 release in normal-weight men and women. Horm Metab Res. 2005; 37(2):111-117.
    • (2005) Horm Metab Res , vol.37 , Issue.2 , pp. 111-117
    • Adam, T.C.1    Westerterp-Plantenga, M.S.2
  • 24
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet. 1998;352(9131):837-853.
    • (1998) Lancet , vol.352 , Issue.9131 , pp. 837-853
  • 25
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet. 1998;352(9131):854-865.
    • (1998) Lancet , vol.352 , Issue.9131 , pp. 854-865
  • 26
    • 38149042694 scopus 로고    scopus 로고
    • An overview of pancreatic beta-cell defects in human type 2 diabetes: Implications for treatment
    • Marchetti P, Dotta F, Lauro D, Purrello F. An overview of pancreatic beta-cell defects in human type 2 diabetes: implications for treatment. Regul Pept. 2008;146(1-3):4-11.
    • (2008) Regul Pept , vol.146 , Issue.1-3 , pp. 4-11
    • Marchetti, P.1    Dotta, F.2    Lauro, D.3    Purrello, F.4
  • 27
    • 0035150648 scopus 로고    scopus 로고
    • Predictors of response to glimepiride in patients with type 2 diabetes mellitus
    • for DIAMETRE
    • Charpentier G, Vaur L, Halimi S, et al; for DIAMETRE. Predictors of response to glimepiride in patients with type 2 diabetes mellitus. Diabetes Metab. 2001;27(5 Pt 1):563-571.
    • (2001) Diabetes Metab , vol.27 , Issue.5 PT. 1 , pp. 563-571
    • Charpentier, G.1    Vaur, L.2    Halimi, S.3
  • 28
    • 84871710499 scopus 로고    scopus 로고
    • Exenatide twice daily: Analysis of effectiveness and safety data stratified by age, sex, race, duration of diabetes, and body mass index
    • Pencek R, Blickensderfer A, Li Y, Brunell SC, Anderson PW. Exenatide twice daily: analysis of effectiveness and safety data stratified by age, sex, race, duration of diabetes, and body mass index. Postgrad Med. 2012;124(4):21-32.
    • (2012) Postgrad Med , vol.124 , Issue.4 , pp. 21-32
    • Pencek, R.1    Blickensderfer, A.2    Li, Y.3    Brunell, S.C.4    Anderson, P.W.5
  • 29
    • 0025148179 scopus 로고
    • Weight as a risk factor for clinical diabetes in women
    • Colditz GA, Willett WC, Stampfer MJ, et al. Weight as a risk factor for clinical diabetes in women. Am J Epidemiol. 1990;132(3):501-513.
    • (1990) Am J Epidemiol , vol.132 , Issue.3 , pp. 501-513
    • Colditz, G.A.1    Willett, W.C.2    Stampfer, M.J.3
  • 30
    • 40949147782 scopus 로고    scopus 로고
    • Gender modulates the relationship between body weight and plasma glucose in overweight or obese subjects
    • Seghieri G, Tesi F, Anichini R, et al. Gender modulates the relationship between body weight and plasma glucose in overweight or obese subjects. Diabetes Res Clin Pract. 2008;80(1):134-138.
    • (2008) Diabetes Res Clin Pract , vol.80 , Issue.1 , pp. 134-138
    • Seghieri, G.1    Tesi, F.2    Anichini, R.3
  • 31
    • 84856758245 scopus 로고    scopus 로고
    • Do women exhibit greater differences in established and novel risk factors between diabetes and non-diabetes than men? The British Regional Heart Study and British Women's Heart Health Study
    • Wannamethee SG, Papacosta O, Lawlor DA, et al. Do women exhibit greater differences in established and novel risk factors between diabetes and non-diabetes than men? The British Regional Heart Study and British Women's Heart Health Study. Diabetologia. 2012;55(1):80-87.
    • (2012) Diabetologia , vol.55 , Issue.1 , pp. 80-87
    • Wannamethee, S.G.1    Papacosta, O.2    Lawlor, D.A.3


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