Azithromycin: A new concept in adjuvant treatment of periodontitis

European Journal of Pharmacology

Volumn 705, Issue 1-3, 2013, Pages 135-139

  Muniz, Francisco Wilker Mustafa Gomes ^a   De Oliveira, Camila Carvalho ^b   De Sousa Carvalho, Rosimary ^a   Moreira, Maria Mônica Studart Mendes ^a   De Moraes, Maria Elisabete Amaral ^a   Martins, Ricardo Souza ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b Federal University   (Brazil)

Author keywords

Azithromycin; Periodontitis; Treatment

Indexed keywords

AMOXICILLIN; AZITHROMYCIN; METRONIDAZOLE; PLACEBO;

ADJUVANT THERAPY; AGGRESSIVE PERIODONTITIS; ANTIBIOTIC RESISTANCE; BACTERIAL FLORA; CHRONIC PERIODONTITIS; DRUG EFFICACY; DRUG HALF LIFE; DRUG HYPERSENSITIVITY; DRUG PENETRATION; DRUG TISSUE LEVEL; DRUG TOLERABILITY; GASTROINTESTINAL DISEASE; HUMAN; INTERMETHOD COMPARISON; PATIENT COMPLIANCE; PERIODONTIUM; PREVENTIVE DENTISTRY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SINGLE DRUG DOSE; SYSTEMATIC REVIEW; TREATMENT DURATION; TREATMENT OUTCOME;

ADJUVANTS, PHARMACEUTIC; ANTI-BACTERIAL AGENTS; AZITHROMYCIN; HUMANS; PERIODONTITIS;

EID: 84875962479     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.02.044     Document Type: Review

References (26)

1. J.W. Costerton, Z. Lewandowski, D.E. Caldwell, D.R. Korber, and H.M. Lappin-Scott Microbial biofilms Annu. Rev. Microbiol. 49 1995 711 745
2. K. Gomi, A. Yashima, T. Nagano, M. Kanazashi, N. Maeda, and T. Arai Effects of full-mouth scaling and root planing in conjunction with systemically administered azithromycin J. Periodontol. 78 2007 422 429
3. R.N. Greenberg Overview of patient compliance with medication dosing: a literature review Clin. Ther. 6 1984 592 599
4. A.N. Haas, G.D. Castro, T. Moreno, C. Susin, J.M. Albandar, R.V. Oppermann, and C.K. Rösing Azithromycin as an adjunctive treatment of aggressive periodontitis: 12-months randomized clinical trial J. Clin. Periodontol. 35 2008 696 704
5. A.D. Haffajee, M. Patel, and S.S. Socransky Microbiological changes associated with four different periodontal therapies for the treatment of chronic periodontitis Oral Microbiol. Immunol. 23 2008 148 157
6. A.D. Haffajee, and S.S. Socransky Microbial etiological agents of destructive periodontal disease Periodontol. 2000 1994 78 111 5 1994 78 111
7. A.D. Haffajee, S.S. Socransky, and J.C. Gunsolley Systemic anti-infective periodontal therapy. A systematic review Ann. Periodontol. 8 2003 115 181
8. A.D. Haffajee, G. Torresyap, and S.S. Socransky Clinical changes following four different periodontal therapies for the treatment of chronic periodontitis: 1-year results J. Clin. Periodontol. 34 2007 243 253
9. D. Herrera, M. Sanz, S. Jepsen, I. Needleman, and S. Roldan A systematic review on the effect of systemic antimicrobials as an adjunct to scaling and root planing in periodontitis patients J. Clin. Periodontol. 29 Suppl 2002 136 159
10. W. Ho, T. Eubank, B. Leblebicioglu, C. Marsh, and J. Walters Azythomycin decreases crevicular fluid volume and mediator content J. Dent. Res. 89 2010 831 835
11. P.D. Marsh Dental plaque as a biofilm and a microbial community-implications for health and disease BMC Oral Health. 6 suppl 2006 1 7
12. P. Mascarenhas, R. Gapski, K. Al-Shammari, R. Hill, S. Soehren, J.C. Fenno, W.V. Giannobile, and H.L. Wang Clinical response of Azithromycin as an adjunct to non-surgical periodontal therapy in smokers J. Periodontol. 76 2005 426 436
13. R.J. McDonald, and H. Pruul Phagocytic uptake and transport of azithromycin Eur. J. Clin. Microbiol. Infect. Dis. 10 1991 828 833
14. T. Morozumi, T. Kubota, D. Abe, T. Shimizu, Y. Komatsu, and H. Yoshie Effects of irrigation with an antiseptic and oral administration of azithromycin on bacteremia caused by scaling and root planing J. Periodontol. 81 2010 1555 1563
15. H.P. Müller, S. Holderrieth, U. Burkhardt, and U. Höffler In vitro antimicrobial susceptibility of oral strains of Actinobacillus actinomycetemcomitans to seven antibiotics J. Clin. Periodontol. 29 2002 736 742
16. A. Oteo, D. Herrera, E. Figuero, A. O'Connor, I. Gonzáles, and M. Sanz Azithromycin as an adjunct to scaling and root planing in the treatment of Porphyromonas gingivalis-associated periodontitis: a pilot study J. Clin. Periodontol. 37 2010 1005 1015
17. J.C. Plaza, F. Gallardo, L. Davila, and M. Rioseco Efectos de uma terapia sistémica con azitromicina em el tratamento de la periodontites crónica Av. Periodon. Implantol. 16 2003 35 42
18. A.R. Pradeep, S.V. Sagar, and H. Daisy Clinical and microbiologic effects of subgingivally delivered 0.5% azithromycin in the treatment of chronic periodontitis J. Periodontol. 79 2008 2125 2135
19. S.P. Ramfjord, J.W. Knowles, R.R. Nissle, F.G. Burgett, and R.A. Shick Results following three modality of periodontal therapy J. Periodontol. 46 1975 522 526
20. J. Retsema, A. Girard, W. Schelkly, M. Manousos, M. Anderson, G. Bright, R. Borovoy, L. Brennan, and R. Mason Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring macrolide with improved potency against gram-negative organisms Antimicrob. Agents. Chemother. 31 1987 1939 1947
21. E. Sampaio, M. Rocha, L.C. Figueiredo, M. Faveri, P.M. Duarte, E.A.G. Lira, and M. Feres Clinical and microbiological effects of azithromycin in the treatment of generalized chronic periodontitis: a randomized placebo-controlled clinical trial J. Clin. Periodontol. 38 2011 838 846
22. J.J. Schentag, and C.H. Ballow Tissue-directed pharmacokinetics Am. J. Med. 91 1991 5S 11S
23. S.R. Smith, D.M. Foyle, J. Daniels, S. Joyston-Bechal, F.C. Smales, A. Sefton, and J. Williams A double-blind placebo-controlled trial of azithromycin as an adjunct to non-surgical treatment of periodontitis in adults: clinical results J. Clin. Periodontol. 29 2002 54 61
24. A. Tanner, M.F.J. Maiden, P. Machuch, L.L. Murray, and R.L. Kent Jr. Microbiota of health, gingivitis and initial periodontitis J. Clin. Periodontol. 25 1998 85 89
25. M. Wilson Susceptibility of oral bacterial biofilms to antimicrobial agents J. Med. Microbiol. 44 1996 79 87
26. A. Yashima, K. Gomi, N. Maeda, and T. Arai One-stage full-mouth versus partial-mouth scaling and root planing during the effective half-life of systemically administered Azithromycin J. Periodontol. 80 2009 1406 1413