Effects of full-mouth scaling and root planning in conjunction with systematically administered azithromycin

Journal of Periodontology

Volumn 78, Issue 3, 2007, Pages 422-429

  Gomi, Kazuhiro ^a   Yashima, Akihiro ^a   Nagano, Takatoshi ^a   Kanazashi, Mikimoto ^a   Maeda, Nobuko ^a   Arai, Takashi ^a  

^a TSURUMI UNIVERSITY   (Japan)

Author keywords

Azithromycin; Bacteria; Dental scaling; Oral administration; Periodontitis; Root planing

Indexed keywords

ANTIINFECTIVE AGENT; AZITHROMYCIN;

ANAEROBIC BACTERIUM; ARTICLE; BACTERIAL COUNT; BODY TEMPERATURE; CHRONIC DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; MALE; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MIDDLE AGED; MULTIMODALITY CANCER THERAPY; ORAL DRUG ADMINISTRATION; PERIODONTICS; PERIODONTITIS; PREOPERATIVE CARE; PREVENTIVE DENTISTRY; RANDOMIZED CONTROLLED TRIAL;

ADMINISTRATION, ORAL; ANTI-BACTERIAL AGENTS; AZITHROMYCIN; BACTERIA, ANAEROBIC; BODY TEMPERATURE; CHRONIC DISEASE; COLONY COUNT, MICROBIAL; COMBINED MODALITY THERAPY; DENTAL SCALING; FEMALE; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; PERIODONTAL INDEX; PERIODONTAL POCKET; PERIODONTITIS; PREOPERATIVE CARE; ROOT PLANING;

EID: 33947675798     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2007.060247     Document Type: Article

References (34)

1. Listgarten MA. Structure of the microbial flora associated with periodontal health and disease in man. A light and electron microscopic study. J Periodontol 1976; 47:1-18.
2. Slots J, Rams TE. Antibiotics in periodontal therapy: Advantages and disadvantages. J Clin Periodontol 1990; 17:479-493.
3. Loesche WJ, Schmidt E, Smith BA, Morrison EC, Caffesse R, Hujoel PP. Effects of metronidazole on periodontal treatment needs. J Periodontol 1991;62: 247-257.
4. Russell RR. Bacteriology of periodontal disease. Curr Opin Dent 1992;2:66-71.
5. Hardie JM. Oral microbiology: Current concepts in the microbiology of dental caries and periodontal disease. Br Dent J 1992; 172:271-278.
6. Tani M, Shibata Y, Hara Y, Kato I. Effects of scaling and root planing on clinical parameters and bacterial flora in periodontal pockets. Nippon Shishubyo Gakkai Kaishi 1989;31:895-904.
7. Magnusson I, Lindhe J, Yoneyama T, Liljenberg B. Recolonization of a subgingival microbiota following scaling in deep pockets. J Clin Periodontol 1984; 11: 193-207.
8. Mousques T, Listgarten MA, Phillips RW. Effect of scaling and root planing on the composition of human subgingival microbial flora. J Periodontal Res 1980; 15:114-151.
9. Sumida S, Ishihara K, Kishi M, Okuda K. Transmission of periodontal disease-associated bacteria from teeth to osseointegrated implant regions. Int J Oral Maxillofac Implants 2002; 17:696-702.
10. Quirynen M, Bollen CML, Vandekerckhove BNA, Dekeyser C, Papaioannou W, Eyssen H. Full- vs. partial-mouth disinfection in the treatment of periodontal infection: Short-term clinical and microbiological observations. J Dent Res 1995;74:1459-1467.
11. Bollen CML, Mongardini C, Papaioannou W, van Steenberghe D, Quirynen M. The effect of a one-stage full-mouth disinfection on different intra-oral niches. Clinical and microbiological observations. J Clin Periodontol 1998;25:56-66.
12. Papaioannou W, Bollen CM, Quirynen M. One-stage full-mouth disinfection to overcome intra-oral transmission of periodontopathogens. Anaerobe 1997;3: 163-168.
13. Vandekerckhove BN, Bollen CM, Dekeyser C, Darius P, Quirynen M. Full- versus partial-mouth disinfection in the treatment of periodontal infections. Long-term clinical observations of a pilot study. Microbiological findings. J Periodontol 1996;67:1251-1259.
14. Apatzidou DA, Kinane DF. Quadrant root planing versus same-day full-mouth root planing. II. Microbiological findings. J Clin Periodontol 2004;31:141-148.
15. Apatzidou DA, Kinane DF. Quadrant root planing versus same-day full-mouth root planing. I. Clinical findings. J Clin Periodontol 2004;31:132-140.
16. Greenstein G. Full-mouth therapy versus individual quadrant root planing: A critical commentary. J Periodontol 2002;73:797-812.
17. Quirynen M, Mongardini C, De Soete M, et al. The role of chlorhexidine in the one-stage full-mouth disfection treatment of patients with advanced adult periodontitis: Long-term clinical and microbiological observations. J Clin Periodontol 2000;27: 578-589.
18. Aguillon JC, Ferreira V, Nunez E, et al. Immunomodulation of LPS ability to induce the local Shwartzman reaction. Scand J Immunol 1996;44:551-555.
19. Gladue RP, Bright GM, Isaacson RE, Newborg MF. In vitro and in vivo uptake of azithromycin (CP-62,993) by phagocytic cells: Possible mechanism of delivery and release at sites of infection. Antimicrob Agents Chemother 1989;33:277-282.
20. Foulds G, Shepard RM, Johnson RB. The pharmacokinetics of azithromycin in human serum and tissue. J Antimicrob Chemother 1990;25(Suppl. A):73-82.
21. McDonald PJ, Pruul H. Phagocyte uptake and transport of azithromycin. Eur J Clin Microbiol Infect Dis 1991;10:828-833.
22. Schentag JJ, Ballow CH. Tissue-directed pharmacokinetics. Am J Med 199 1;91:5S-11S.
23. Gomi K, Yashima A, lino F, et al. Drug concentration in inflamed periodontal tissues following systemically administrated azithromycin. J Periodontol 2007; in press.
24. Löe H, Silness J. Periodontal disease in pregnancy. 3. Response to local treatment. Acta Odontol Scand 1963; 21:533-551.
25. Ashimoto A, Chen C, Bakker I, Slots J. Polymerase chain reaction detection of 8 putative periodontal pathogens in subgingival plaque of gingivitis and advanced periodontitis lesions. Oral Microbiol Immunol 1996; 11:266-273.
26. Socransky SS, Haffajee AD, Ximenez-Fyvie LA, Feres M, Mager D. Ecological considerations in the treatment of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis periodontal infections. Periodontol 2000 1999;20:341-362.
27. Takeda K. Quorum-sensing system that modulates both bacterial virulence factor expression and host responses. Bacterial Adherence Biofilm 2002;16: 11-17.
28. Flemmig TF, Milian E, Kopp C, Karch H, Klaiber B. Differential effects of systemic metronidazole and amoxicillin on Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in intraoral habitats. J Clin Periodontol 1998;25:1-10.
29. Lopez NJ, Gamonal JA, Martinez B. Repeated metronidazole and amoxicillin treatment of periodontitis: A follow-up study. J Periodontol 2000;71:79-89.
30. Winkel EG, van Winkelhoff AJ, Timmerman MF, van der Velden, van der Weijden GA. Amoxicillin plus metronidazole in the treatment of adult periodontitis patient: A double-blind placebo-controlled study. J Clin Periodontol 2001;28:296-305.
31. Feres M, Haffajee AD, Allard K, Som S, Socransky SS. Change in subgingival microbial profiles in adult periodontitis subjects receiving either systemically-administered amoxicillin or metronidazole. J Clin Periodontol 2001;28:597-609.
32. Haffajee AD, Uzel NG, Arguello EL, Torresyap G, Guerrero DM, Socransky SS. Clinical and microbiological changes associated with the use of combined antimicrobial therapies to treat "refractory" periodontitis. J Clin Periodontol 2004;31:869-877.
33. Retsema JA, Bergeron JM, Girard D, Milisen WB, Girard AE. Preferential concentration of azithromycin in an infected mouse thigh model. J Antimicrob Chemother 1993;31 (Suppl. E):5-16.
34. Fiese EF, Steffen SH. Comparison of the acid stability of azithromycin and erythromycin A. J Antimicrob Chemother 1990;25(Suppl. A):39-47.