Cholesteryl ester transfer protein and ATP-binding cassette transporter A1 genotype alter the atorvastatin and simvastatin efficacy: Time for genotype-guided therapy?

Angiology

Volumn 64, Issue 4, 2013, Pages 266-272

  Kolovou, Genovefa ^a   Kolovou, Vana ^a   Mihas, Constantinos ^b   Giannakopoulou, Vasiliki ^a   Vasiliadis, Iannis ^a   Boussoula, Elena ^a   Kollia, Aikaterini ^a   Boutsikou, Maria ^a   Katsiki, Niki ^c   Mavrogeni, Sophie ^a  

^a ONASSIS CARDIAC SURGERY CENTER   (Greece)

^b Kimi General Hospital   (Greece)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

atorvastatin; ATP binding cassette transporter A1 (ABCA1) gene; cholesteryl ester transfer protein (CETP) gene; simvastatin

Indexed keywords

ABC TRANSPORTER A1; ATORVASTATIN; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SIMVASTATIN; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; CHOLESTEROL BLOOD LEVEL; COHORT ANALYSIS; DRUG EFFICACY; DRUG RESPONSE; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; HYPERCHOLESTEROLEMIA; MAJOR CLINICAL STUDY; MALE; PHARMACOGENETICS; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TRIACYLGLYCEROL BLOOD LEVEL;

AGED; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL MARKERS; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEINS; CHOLESTEROL, HDL; CHOLESTEROL, LDL; FEMALE; GENE FREQUENCY; GENOTYPE; HEPTANOIC ACIDS; HUMANS; HYPERCHOLESTEROLEMIA; INDIVIDUALIZED MEDICINE; MALE; MIDDLE AGED; PATIENT SELECTION; PHENOTYPE; POLYMORPHISM, GENETIC; PYRROLES; SIMVASTATIN; TREATMENT OUTCOME;

EID: 84875929331     PISSN: 00033197     EISSN: 19401574     Source Type: Journal    
DOI: 10.1177/0003319712444594     Document Type: Article

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