TRPA1 receptors in cough

Pulmonary Pharmacology and Therapeutics

Volumn 24, Issue 3, 2011, Pages 286-288

  Grace, Megan S ^a   Belvisi, Maria G ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Cough; Lung; Sensory nerves

Indexed keywords

ACROLEIN; ANKYRIN; ANTITUSSIVE AGENT; CALCIUM; CAPSAICIN; IRRITANT AGENT; PROTON; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; VANILLOID RECEPTOR AGONIST;

AIR POLLUTION; ARTICLE; BREATHING PATTERN; COUGHING; DYSPNEA; ELECTROPHILICITY; GUINEA PIG; HUMAN; HYPERALGESIA; INFLAMMATION; LUNG; MECHANICAL STIMULATION; NEUROGENIC INFLAMMATION; NOCICEPTIVE STIMULATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RESPIRATORY SYSTEM; RODENT; SENSORY NERVE; SMOKE; STIMULATION; TEMPERATURE; THERMORECEPTOR; VAGUS NERVE;

ANIMALS; ANTITUSSIVE AGENTS; CALCIUM; CALCIUM CHANNELS; COUGH; DRUG DELIVERY SYSTEMS; DRUG DESIGN; HUMANS; INFLAMMATION; LUNG; NERVE TISSUE PROTEINS; NEURONS, AFFERENT; OXIDATIVE STRESS; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 79955732680     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2010.11.002     Document Type: Article

References (37)

1. Laude E.A., Higgins K.S., Morice A.H. A comparative study of the effects of citric acid, capsaicin and resiniferatoxin on the cough challenge in guinea-pig and man. Pulm Pharmacol 1993, 6:171-175.
2. Lalloo U.G., Fox A.J., Belvisi M.G., Chung K.F., Barnes P.J. Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs. J Appl Physiol 1995, 79:1082-1087.
3. Trevisani M., Milan A., Gatti R., Zanasi A., Harrison S., Fontana G., et al. Antitussive activity of iodo-resiniferatoxin in guinea pigs. Thorax 2004, 59:769-772.
4. Groneberg D.A., Niimi A., Dinh Q.T., Cosio B., Hew M., Fischer A., et al. Increased expression of transient receptor potential vanilloid-1 in airway nerves of chronic cough. Am J Respir Crit Care Med 2004, 170:1276-1280.
5. Bautista D.M., Jordt S.E., Nikai T., Tsuruda P.R., Read A.J., Poblete J., et al. TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell 2006, 124:1269-1282.
6. Jaquemar D., Schenker T., Trueb B. An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts. J Biol Chem 1999, 274:7325-7333.
7. Story G.M., Peier A.M., Reeve A.J., Eid S.R., Mosbacher J., Hricik T.R., et al. ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 2003, 112:819-829.
8. McNamara C.R., Mandel-Brehm J., Bautista D.M., Siemens J., Deranian K.L., Zhao M., et al. TRPA1 mediates formalin-induced pain. Proc Natl Acad Sci USA 2007, 104:13525-13530.
9. Andrè E., Campi B., Materazzi S., Trevisani M., Amadesi S., Massi D., et al. Cigarette smoke-induced neurogenic inflammation is mediated by alpha, beta-unsaturated aldehydes and the TRPA1 receptor in rodents. J Clin Invest 2008, 118:2574-2582.
10. Bandell M., Story G.M., Hwang S.W., Viswanath V., Eid S.R., Petrus M.J., et al. Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron 2004, 41:849-857.
11. Jordt S.-E., Bautista D.M., Chuang H., McKemy D.D., Zygmunt P.M., Högestätt E.D., et al. Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 2004, 427:260-265.
12. Bautista D.M., Movahed P., Hinman A., Alexsson H.E., Sterner O., Högestätt E.D., et al. Pungent products from garlic activate the sensory ion channel TRPA1. PNAS 2005, 102:12248-12252.
13. Taylor-Clark T.E., McAlexander M.A., Nassenstein C., Sheardown S.A., Wilson S., Thornton J., et al. Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C-fibres by the endogenous autocoid 4-oxononenal. J Physiol 2008, 586:3447-3459.
14. Simon S.A., Liedtke W. How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways. J Clin Invest 2008, 118:2383-2386.
15. Macpherson L.J., Dubin A.D., Evans M.J., Marr F., Schultz P.G., Cravatt B.F., et al. Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nat Lett 2007, 445:541-545.
16. 2+. Nat Neurosci 2007, 10:277-279.
17. Kwan K.Y., Allchorne A.J., Vollrath M.A., Christiensen A.P., Zhang D.-S., Woolf C.J., et al. TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction. Neuron 2006, 50:277-289.
18. Trevisani M., Siemens J., Materazzi S., Bautista D.M., Nassini R., Campi B., et al. 4-hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. PNAS 2007, 104:13519-13524.
19. Karashima Y., Talavera K., Everaerts W., Janssens A., Kwan K.Y., Vennekens R., et al. TRPA1 acts as a cold sensor in vitro and in vivo. PNAS 2009, 106:1273-1278.
20. Nagata K., Duggan A., Kumar G., Garcia Anoveros J. Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing. J Neurosci 2005, 25:4052-4061.
21. McCormick A., Fleming D.M., Charlton J. Office of population censuses and surveys. Series MB5 no 3 1995, HMSO, London.
22. Ford A.C., Forman D., Moayyedi P., Morice A.H. Cough in the community: a cross sectional survey and the relationship to gastrointestinal symptoms. Thorax 2006, 61:975-979.
23. Schroeder K., Fahey T. Systematic review of randomised controlled trials of over the counter cough medicines for acute cough in adults. BMJ 2002, 324:329-331.
24. Reynolds S.M., Mackenzie A.J., Spina D., Page C.P. The pharmacology of cough. Trends Pharmacol Sci 2004, 25:569-576.
25. Belvisi M.G., Geppetti P. Cough 7: Current and future drugs for the treatment of chronic cough. Thorax 2004, 59:438-440.
26. Karlsson J.-A., Fuller R.W. Pharmacological regulation of the cough reflex-from experimental models to antitussive effects in man. Pulm Pharmacol Ther 1999, 12:215-228.
27. Bessac B.F., Sivula M., von Hehn C.A., Escalera J., Cohn L., Jordt S.-E. TRPA1 is a major oxidant sensor in murine airway sensory neurons. J Clin Invest 2008, 118:1899-1910.
28. Nassenstein C., Kwong K., Taylor-Clark T., Kollarik M., Macglashan D.M., Braun A., et al. Expression and function of the ion channel TRPA1 in vagal afferent nerves innervating mouse lungs. J Physiol 2008, 586:1595-1604.
29. Taylor-Clark T.E., Nassenstein C., McAlexander M.A., Undem B.J. TRPA1: a potential target for antitussive therapy. Pulm Pharmacol Ther 2009, 22:71-74.
30. Birrell M.A., Belvisi M.G., Grace M., Sadofsky L., Faruqi S., Hele D.J., et al. TRPA1 agonists evoke coughing in guinea pig and human volunteers. Am J Respir Crit Care Med 2009, 180:1042-1047.
31. Andrè E., Gatti R., Trevisani M., Preti D., Baraldi P.G., Patacchini R., et al. Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents. Br J Pharmacol 2009, 158:1621-1628.
32. Doherty M.J., Mister R., Pearson M.G., Calverley P.M.A. Capsaicin responsiveness and cough in asthma and chronic obstructive pulmonary disease. Thorax 2000, 55:643-649.
33. Pecova R., Zucha J., Pec M., Neuschlova M., Hanzel P., Tatar M. Cough reflex sensitivity testing in seasonal allergic rhinitis patients and healthy volunteers. J Physiol Pharmacol 2008, 59(Suppl. 6):557-564.
34. Nemoto T., Aoki H., Ike A., Yamada K., Kondo T. Serum prostaglandin levels in asthmatic patients. J Allergy Clin Immunol 1976, 57:89-94.
35. Montuschi P., Kharitonov S.A., Ciabattoni G., Barnes P.J. Exhaled leukotrienes and prostaglandins in COPD. Thorax 2003, 58:585-588.
36. 2 concentrations and cyclooxygenase-2 expression in asthmatic subjects with sputum eosinophilia. J Allergy Clin Immunol 2003, 112:709-716.
37. 2+ reveals different functional channel states. Neuroscience 2008, 154:1467-1476.