Induction of matrix metalloproteinase-2 and -9 via Erk1/2-NF-κB pathway in human astroglia infected with Toxoplasma gondii

Acta Tropica

Volumn 127, Issue 1, 2013, Pages 14-20

  Lu, Cheng You ^a   Lai, Shih Chan ^a,b  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Erk1 2; MMP 2; MMP 9; NF B; T. gondii; Toxoplasmic encephalitis

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

DISEASE TREATMENT; ENCEPHALITIS; ENZYME; GENE EXPRESSION; INFECTIOUS DISEASE; NERVOUS SYSTEM;

ARTICLE; ASTROCYTE; BINDING SITE; CELL FREE SYSTEM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; MACROGLIA; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; TACHYZOITE; TOXOPLASMA GONDII; TOXOPLASMOSIS;

ASTROCYTES; CELL LINE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; LEUPEPTINS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NF-KAPPA B; PROMOTER REGIONS, GENETIC; TOXOPLASMA;

TOXOPLASMA GONDII;

EID: 84875919758     PISSN: 0001706X     EISSN: 18736254     Source Type: Journal    
DOI: 10.1016/j.actatropica.2013.03.004     Document Type: Article

References (31)

1. Ambroise-Thomas P., Pelloux H. Toxoplasmosis-congenital and in immunocompromised patients: a parallel. Parasitol. Today 1993, 9:61-63.
2. Camps M., Nichols A., Arkinstall S. Dual specificity phosphatases: a gene family for control of MAP kinase function. FASEB J. 2000, 14:6-16.
3. Chen K.M., Lee H.H., Lu K.H., Tseng Y.K., Hsu L.S., Chou H.L., Lai S.C. Association of matrix metalloproteinase-9 and Purkinje cell degeneration in mouse cerebellum caused by Angiostrongylus cantonensis. Int. J. Parasitol. 2004, 34:1147-1156.
4. Chen P., Li J., Barnes J., Kokkonen G.C., Lee J.C., Liu Y. Restraint of proinflammatory cytokine biosynthesis by mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages. J. Immunol. 2002, 169:6408-6416.
5. Doddareddy M.R., Rawling T., Ammit A.J. Targeting mitogen-activated protein kinase phosphatase-1 (MKP-1): structure-based design of MKP-1 inhibitors and upregulators. Curr. Med. Chem. 2012, 19:163-173.
6. Farina A.R., Tacconelli A., Vacca A., Maroder M., Gulino A., Mackay A.R. Transcriptional up-regulation of matrix metalloproteinase-9 expression during spontaneous epithelial to neuroblast phenotype conversion by SK-N-SH neuroblastoma cells, involved in enhanced invasivity, depends upon GTbox and nuclear factor kappa B elements. Cell Growth Differ. 1999, 10:353-367.
7. Fields R.D., Stevens-Graham B. New insights into neuron-glia communication. Science 2002, 298:556-562.
8. Hovsepian E., Mirkin G.A., Penas F., Manzano A., Bartrons R., Goren N.B. Modulation of inflammatory response and parasitism by 15-Deoxy- δ(12,14) prostaglandin J(2) incruzi-infected cardiomyocytes. Int. J. Parasitol. 2011, 41:553-562.
9. Hsieh H.L., Wang H.H., Wu W.B., Chu P.J., Yang C.M. Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways. J. Neuroinflammation. 2010, 7:88.
10. Hunter C.A., Roberts C.W., Alexander J. Kinetics of cytokine mRNA production in the brains of mice with progressive toxoplasmic encephalitis. Eur. J. Immunol. 1992, 22:2317-2322.
11. Johnson G.L., Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002, 298:1911-1912.
12. Ju C.H., Chockalingam A., Leifer C.A. Early response of mucosal epithelial cells during Toxoplasma gondii infection. J. Immunol. 2009, 183:7420-7427.
13. Ju S.M., Song H.Y., Lee J.A., Lee S.J., Choi S.Y., Park J. Extracellular HIV-1 Tat up-regulates expression of matrix metalloproteinase-9 via a MAPK-NF-κB dependent pathway in human astrocytes. Exp. Mol. Med. 2009, 41:86-93.
14. Keyse S.M. Protein phosphatases and the regulation of mitogen-activated protein kinase signalling. Curr. Opin. Cell Biol. 2000, 12:186-192.
15. Kim L., Butcher B.A., Denkers E.Y. Toxoplasma gondii interferes with lipopolysaccharide-induced mitogen-activated protein kinase activation by mechanisms distinct from endotoxin tolerance. J. Immunol. 2004, 172:3003-3010.
16. Kim J.Y., Ahn M.H., Song H.O., Choi J.H., Ryu J.S., Min D.Y., Cho M.H. Involvement of MAPK activation in chemokine or COX-2 productions by Toxoplasma gondii. Korean J. Parasitol. 2006, 44:197-207.
17. Kim L., Denkers E.Y. Toxoplasma gondii triggers Gi-dependent PI 3-kinase signaling required for inhibition of host cell apoptosis. J. Cell Sci. 2006, 119:2119-2126.
18. Lee H.H., Chou H.L., Chen K.M., Lai S.C. Association of matrix metalloproteinase-9 in eosinophilic meningitis of BALB/c mice caused by Angiostrongylus cantonensis. Parasitol. Res. 2004, 94:321-328.
19. Lee W.J., Shin C.Y., Yoo B.K., Ryu J.R., Choi E.Y., Cheong J.H., Ryu J.H., Ko K.H. Induction of matrix metalloproteinase-9 (MMP-9) in lipopolysaccharide-stimulated primary astrocytes is mediated by extracellular signal-regulated protein kinase 1/2 (Erk1/2). Glia 2003, 41:15-24.
20. Lu C.Y., Lai S.C. Matrix metalloproteinase-2 and -9 lead to fibronectin degradation in astroglia infected with Toxoplasma gondii. Acta Trop. 2013, 125:320-329.
21. Pagenstecher A., Stalder A.K., Kincaid C.L., Shapiro S.D., Campbell I.L. Differential expression of matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase genes in the mouse central nervous system in normal and inflammatory states. Am. J. Pathol. 1998, 152:729-741.
22. Pelloux H., Pernod G., Polack B., Coursange E., Ricard J., Verna J.M., Ambroise-Thomas P. Influence of cytokines on Toxoplasma gondii growth in human astrocytoma-derived cells. Parasitol. Res. 1996, 82:598-603.
23. Peterson P.K., Gekker G., Hu S., Chao C.C. Intracellular survival and multiplication of Toxoplasma gondii in astrocytes. J. Infect. Dis. 1993, 168:1472-1478.
24. Qin L.Y., Li M.N., Ren W.J., Zhang D., Zhang J.L., Zhang Y.H., Cheng N.L. Silencing pin1 suppresses the expression and bioactivity of MMP-9 through NF-κB in colorectal carcinoma SW480 Cells. Clin. Oncol. Cancer. Res. 2010, 7:12-17.
25. Sabin A.B., Olitsky P.K. Toxoplasma and obligate intracellular parasitism. Science 1937, 85:336-338.
26. Shim Y.J., Kang B.H., Jeon H.S., Park I.S., Lee K.U., Lee I.K., Park G.H., Lee K.M., Schedin P., Min B.H. Clusterin induces matrix metalloproteinase-9 expression via ERK1/2 and PI3K/Akt/NF-κB pathways in monocytes/macrophages. J. Leukoc. Biol. 2011, 90:761-769.
27. Sun H., Charles C.H., Lau L.F., Tonks N.K. MKP-1(3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell 1993, 75:487-493.
28. Valère A., Garnotel R., Villena I., Guenounou M., Pinon J.M., Aubert D. Activation of the cellular mitogen-activated protein kinase pathways ERK, P38 and JNK during Toxoplasma gondii invasion. Parasite 2003, 10:59-64.
29. Wilson E.H., Hunter C.A. The role of astrocytes in the immunopathogenesis of toxoplasmic encephalitis. Int. J. Parasitol. 2004, 34:543-548.
30. Wu C.Y., Hsieh H.L., Jou M.J., Yang C.M. Involvement of p42/p44 MAPK, p38 MAPK, JNK and nuclear factor-kappa B in interleukin-1 beta-induced matrix metalloproteinase-9 expression in rat brain astrocytes. J. Neurochem. 2004, 90:1477-1488.
31. Yeh J.L., Hsu J.H., Hong Y.S., Wu J.R., Liang J.C., Wu B.N., Chen I.J., Liou S.F. Eugenolol and glyceryl-isoeugenol suppress LPS-induced iNOS expression by down-regulating NF-kappaB AND AP-1 through inhibition of MAPKS and AKT/IkappaBalpha signaling pathways in macrophages. Int. J. Immunopathol. Pharmacol. 2011, 24:345-356.