Endogenous stromal cell-derived factor-1 (CXCL12) supports autonomous growth of acute myeloid leukemia cells

Leukemia Research

Volumn 37, Issue 5, 2013, Pages 566-572

  Kim, Ha Yon ^a,b   Oh, Yoon Suk ^a,b   Song, Ik Chan ^a,b   Kim, Seong Woo ^a   Lee, Hyo Jin ^a,b   Yun, Hwan Jung ^a,b   Kim, Samyong ^a,b   Jo, Deog Yeon ^a,b  

^a Chungnam National University   (South Korea)

^b Daejeon Regional Cancer Center   (South Korea)

Author keywords

Acute myeloid leukemia; Apoptosis; Cell proliferation; CXCL12; CXCR4; SDF 1

Indexed keywords

CD34 ANTIGEN; SMALL INTERFERING RNA; STROMAL CELL DERIVED FACTOR 1;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CANCER GROWTH; CELL FUNCTION; CELL PROLIFERATION; CELL SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; LEUKEMIA CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

CELL PROLIFERATION; CHEMOKINE CXCL12; FEMALE; GENE EXPRESSION REGULATION, LEUKEMIC; GENE KNOCKDOWN TECHNIQUES; HL-60 CELLS; HUMANS; K562 CELLS; LEUKEMIA, MYELOID, ACUTE; MALE; NEOPLASM PROTEINS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; U937 CELLS;

EID: 84875889588     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2013.01.016     Document Type: Article

References (22)

1. Peled A., Petit I., Kollet O., Magid M., Ponomaryov T., Byk T., et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science 1999, 283:845-848.
2. + hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1. Blood 1998, 91:4523-4530.
3. Mohle R., Schittenhelm M., Failenschmid C., Bautz F., Kratz-Albers K., Serve H., et al. Functional response of leukaemic blasts to stromal cell-derived factor-1 correlates with preferential expression of the chemokine receptor CXCR4 in acute myelomonocytic and lymphoblastic leukaemia. Br J Haematol 2000, 110:563-572.
4. Voermans C., van Heese W.P., de Jong I., Gerritsen W.R., van Der Schoot C.E. Migratory behavior of leukemic cells from acute myeloid leukemia patients. Leukemia 2002, 16:650-657.
5. Tavor S., Petit I., Porozov S., Avigdor A., Dar A., Leider-Trejo L., et al. CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice. Cancer Res 2004, 64:2817-2824.
6. Majka M., Rozmyslowicz T., Honczarenko M., Ratajczak J., Wasik M.A., Gaulton G.N., et al. Biological significance of the expression of HIV-related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines. Leukemia 2000, 14:1821-1832.
7. Rombouts E.J., Pavic B., Lowenberg B., Ploemacher R.E. Relation between CXCR-4 expression, Flt3 mutations, and unfavorable prognosis of adult acute myeloid leukemia. Blood 2004, 104:550-557.
8. Dommange F., Cartron G., Espanel C., Gallay N., Domenech J., Benboubker L., et al. CXCL12 polymorphism and malignant cell dissemination/tissue infiltration in acute myeloid leukemia. FASEB J 2006, 20:1913-1915.
9. Kalinkovich A., Tavor S., Avigdor A., Kahn J., Brill A., Petit I., et al. Functional CXCR4-expressing microparticles and SDF-1 correlate with circulating acute myelogenous leukemia cells. Cancer Res 2006, 66:11013-11020.
10. Lataillade J.J., Clay D., Bourin P., Herodin F., Dupuy C., Jasmin C., et al. Stromal cell-derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G(0)/G(1) transition in CD34(+) cells: evidence for an autocrine/paracrine mechanism. Blood 2002, 99:1117-1129.
11. Liesveld J.L., Bechelli J., Rosell K., Lu C., Bridger G., Phillips G., et al. Effects of AMD3100 on transmigration and survival of acute myelogenous leukemia cells. Leuk Res 2007, 31:1553-1563.
12. Tavor S., Eisenbach M., Jacob-Hirsch J., Golan T., Petit I., Benzion K., et al. The CXCR4 antagonist AMD3100 impairs survival of human AML cells and induces their differentiation. Leukemia 2008, 22:2151-5158.
13. Kim H.Y., Hwang J.Y., Oh Y.S., Kim S.W., Lee H.J., Yun H.J., et al. Differential effects of CXCR4 antagonists on the survival and proliferation of myeloid leukemia cells in vitro. Korean J Hematol 2011, 46:244-252.
14. Beider K., Abraham M., Begin M., Wald H., Weiss I.D., Wald O., et al. Interaction between CXCR4 and CCL20 pathways regulates tumor growth. PLoS One 2009, 4:e5125.
15. Balabanian K., Lagane B., Infantino S., Chow K.Y., Harriague J., Moepps B., et al. The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes. J Biol Chem 2005, 280:35760-35766.
16. Miao Z., Luker K.E., Summers B.C., Berahovich R., Bhojani M.S., Rehemtulla A., et al. CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature. Proc Natl Acad Sci U S A 2007, 104:15735-15740.
17. Meijer J., Ogink J., Roos E. Effect of the chemokine receptor CXCR7 on proliferation of carcinoma cells in vitro and in vivo. Br J Cancer 2008, 99:1493-1501.
18. Moepps B., Frodl R., Rodewald H.R., Baggiolini M., Gierschik P. Two murine homologues of the human chemokine receptor CXCR4 mediating stromal cell-derived factor 1alpha activation of Gi2 are differentially expressed in vivo. Eur J Immunol 1997, 27:2102-2112.
19. Rajagopal S., Kim J., Ahn S., Craig S., Lam C.M., Gerard N.P., et al. Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7. Proc Natl Acad Sci U S A 2010, 107:628-632.
20. Teicher B.A., Fricker S.P. CXCL12 (SDF-1)/CXCR4 pathway in cancer. Clin Cancer Res 2010, 16:2927-2931.
21. Lataillade J.J., Clay D., Dupuy C., Rigal S., Jasmin C., Bourin P., et al. Chemokine SDF-1 enhances circulating CD34(+) cell proliferation in synergy with cytokines: possible role in progenitor survival. Blood 2000, 95:756-768.
22. Lee Y., Gotoh A., Kwon H.J., You M., Kohli L., Mantel C., et al. Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines. Blood 2002, 99:4307-4317.