Limbic hyperactivity associated to verbal memory deficit in schizophrenia

Journal of Psychiatric Research

Volumn 47, Issue 6, 2013, Pages 843-850

  Suazo, Vanessa ^a,b   Díez, álvaro ^a,c   Tamayo, Pilar ^a,d   Montes, Carlos ^a,d   Molina, Vicente ^a,b,e,f  

^a INSTITUTO DE INVESTIGACIÓN BIOMÉDICA DE SALAMANCA IBSAL   (Spain)

^b UNIVERSITY OF SALAMANCA   (Spain)

^c UNIVERSITY OF SALAMANCA   (Spain)

^d HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

^e HOSPITAL CLÍNICO UNIVERSITARIO DE VALLADOLID   (Spain)

^f UNIVERSITY OF VALLADOLID   (Spain)

Author keywords

DLPFC region; Hippocampus; P300; Perfusion; Schizophrenia

Indexed keywords

ADULT; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN PERFUSION; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HIPPOCAMPUS; HUMAN; HYPERACTIVITY; MALE; MEMORY DISORDER; PARANOID SCHIZOPHRENIA; PHOTON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; PRIORITY JOURNAL; VERBAL MEMORY; WORKING MEMORY;

EID: 84875881356     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2013.02.007     Document Type: Article

References (38)

1. Ashburner J., Barnes G., Chen C.-C., Daunizeau J., Flandin G., Friston K., et al. SPM8. User manual 2012, The FIL Methods Group, London.
2. Blanchard J.J., Neale J.M. The neuropsychological signature of schizophrenia: generalized or differential deficit?. American Journal of Psychiatry 1994, 151:40-48.
3. Bledowski C., Prvulovic D., Hoechstetter K., Scherg M., Wibral M., Goebel R., et al. Localizing P300 generators in visual target and distractor processing: a combined event-related potential and functional magnetic resonance imaging study. Journal of Neuroscience 2004, 24:9353-9360.
4. Brain vision analyzer: user manual 2006, Brain Products GmbH, 55-56.
5. Brown G.G., McCarthy G., Bischoff-Grethe A., Ozyurt B., Greve D., Potkin S.G., et al. Brain-performance correlates of working memory retrieval in schizophrenia: a cognitive modeling approach. Schizophrenia Bulletin 2009, 35:32-46.
6. Buckner R.L., Andrews-Hanna J.R., Schacter D.L. The brain's default network: anatomy, function, and relevance to disease. Annals of the New York Academy of Sciences 2008, 1124:1-38.
7. Callicott J.H., Bertolino A., Mattay V.S., Langheim F.J., Duyn J., Coppola R., et al. Physiological dysfunction of the dorsolateral prefrontal cortex in schizophrenia revisited. Cerebral Cortex 2000, 10:1078-1092.
8. Diwadkar V.A., Pruitt P., Zhang A., Radwan J., Keshavan M.S., Murphy E., et al. The neural correlates of performance in adolescents at risk for schizophrenia: inefficiently increased cortico-striatal responses measured with fMRI. Journal of Psychiatric Research 2012, 46:12-21.
9. Habel U., Pauly K., Koch K., Kellermann T., Reske M., Backes V., et al. Emotion-cognition interactions in schizophrenia. World Journal of Biological Psychiatry 2010, 11:934-944.
10. Hasan A., Wobrock T., Falkai P., Schneider-Axmann T., Guse B., Backens M., et al. Hippocampal integrity and neurocognition in first-episode schizophrenia: a multidimensional study. World Journal of Biological Psychiatry 2011.
11. Heckers S., Rauch S.L., Goff D., Savage C.R., Schacter D.L., Fischman A.J., et al. Impaired recruitment of the hippocampus during conscious recollection in schizophrenia. Nature Neuroscience 1998, 1:318-323.
12. Hoff A.L., Riordan H., O'Donnell D.W., Morris L., DeLisi L.E. Neuropsychological functioning of first-episode schizophreniform patients. American Journal of Psychiatry 1992, 149:898-903.
13. Holcomb H.H., Cascella N.G., Thaker G.K., Medoff D.R., Dannals R.F., Tamminga C.A. Functional sites of neuroleptic drug action in the human brain: PET/FDG studies with and without haloperidol. American Journal of Psychiatry 1996, 153:41-49.
14. Kay S.R., Fiszbein A., Opler L.A. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin 1987, 13:261-276.
15. Kircher T., Weis S., Leube D., Freymann K., Erb M., Jessen F., et al. Anterior hippocampus orchestrates successful encoding and retrieval of non-relational memory: an event-related fMRI study. European Archives of Psychiatry and Clinical Neurosciences 2008, 258:363-372.
16. Klar A.A., Ballmaier M., Leopold K., Hake I., Schaefer M., Bruhl R., et al. Interaction of hippocampal volume and N-acetylaspartate concentration deficits in schizophrenia: a combined MRI and 1H-MRS study. Neuroimage 2010, 53:51-57.
17. Konradi C., Yang C.K., Zimmerman E.I., Lohmann K.M., Gresch P., Pantazopoulos H., et al. Hippocampal interneurons are abnormal in schizophrenia. Schizophrenia Research 2011, 131:165-173.
18. Lahti A.C., Holcomb H.H., Weiler M.A., Medoff D.R., Tamminga C.A. Functional effects of antipsychotic drugs: comparing clozapine with haloperidol. Biological Psychiatry 2003, 53:601-608.
19. Liddle E.B., Bates A.T., Das D., White T.P., Groom M.J., Jansen M., et al. Inefficient cerebral recruitment as a vulnerability marker for schizophrenia. Psychological Medicine 2013, 43:169-182.
20. Linden D.E., Prvulovic D., Formisano E., Vollinger M., Zanella F.E., Goebel R., et al. The functional neuroanatomy of target detection: an fMRI study of visual and auditory oddball tasks. Cerebral Cortex 1999, 9:815-823.
21. Ludowig E., Bien C.G., Elger C.E., Rosburg T. Two P300 generators in the hippocampal formation. Hippocampus 2010, 20:186-195.
22. Manoach D.S. Prefrontal cortex dysfunction during working memory performance in schizophrenia: reconciling discrepant findings. Schizophrenia Research 2003, 60:285-298.
23. Manoach D.S., Press D.Z., Thangaraj V., Searl M.M., Goff D.C., Halpern E., et al. Schizophrenic subjects activate dorsolateral prefrontal cortex during a working memory task, as measured by fMRI. Biological Psychiatry 1999, 45:1128-1137.
24. Manoach D.S., Gollub R.L., Benson E.S., Searl M.M., Goff D.C., Halpern E., et al. Schizophrenic subjects show aberrant fMRI activation of dorsolateral prefrontal cortex and basal ganglia during working memory performance. Biological Psychiatry 2000, 48:99-109.
25. Manschreck T.C., Maher B.A., Candela S.F., Redmond D., Yurgelun-Todd D., Tsuang M. Impaired verbal memory is associated with impaired motor performance in schizophrenia: relationship to brain structure. Schizophrenia Research 2000, 43:21-32.
26. Mason M.F., Norton M.I., Van Horn J.D., Wegner D.M., Grafton S.T., Macrae C.N. Wandering minds: the default network and stimulus-independent thought. Science 2007, 315:393-395.
27. Molina V., Gispert J.D., Reig S., Sanz J., Pascau J., Santos A., et al. Cerebral metabolic changes induced by clozapine in schizophrenia. Psychopharmacology 2005, 178:17-26.
28. Molina V., Sarramea F., Sanz J., Benito C., Palomo T. Prefrontal atrophy in first episodes of schzophrenia associated with limbic hyperactivity. Journal of Psychiatric Research 2005, 39:117-127.
29. Molina V., Solera S., Sanz J., Sarramea F., Luque R., Rodriguez R., et al. Association between cerebral metabolic and structural abnormalities and cognitive performance in schizophrenia. Psychiatry Research 2009, 173:88-93.
30. Ongur D., Lundy M., Greenhouse I., Shinn A.K., Menon V., Cohen B.M., et al. Default mode network abnormalities in bipolar disorder and schizophrenia. Psychiatry Research 2010, 183:59-68.
31. Pomarol-Clotet E., Salvador R., Sarro S., Gomar J., Vila F., Martinez A., et al. Failure to deactivate in the prefrontal cortex in schizophrenia: dysfunction of the default mode network?. Psychological Medicine 2008, 38:1185-1193.
32. Ragland J.D., Gur R.C., Valdez J., Turetsky B.I., Elliott M., Kohler C., et al. Event-related fMRI of frontotemporal activity during word encoding and recognition in schizophrenia. American Journal of Psychiatry 2004, 161:1004-1015.
33. Segarra N., Bernardo M., Gutierrez F., Justicia A., Fernadez-Egea E., Allas M., et al. Spanish validation of the Brief Assessment in Cognition in Schizophrenia (BACS) in patients with schizophrenia and healthy controls. European Psychiatry 2011, 26:69-73.
34. Steen R.G., Hamer R.M., Lieberman J.A. Measurement of brain metabolites by 1H magnetic resonance spectroscopy in patients with schizophrenia: a systematic review and meta-analysis. Neuropsychopharmacology 2005, 30:1949-1962.
35. Weiss A.P., Ellis C.B., Roffman J.L., Stufflebeam S., Hamalainen M.S., Duff M., et al. Aberrant frontoparietal function during recognition memory in schizophrenia: a multimodal neuroimaging investigation. Journal of Neuroscience 2009, 29:11347-11359.
36. Whitfield-Gabrieli S., Thermenos H.W., Milanovic S., Tsuang M.T., Faraone S.V., McCarley R.W., et al. Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia. Proceedings of the National Academy of Sciences 2009, 106:1279-1284.
37. Woods S.W. Chlorpromazine equivalent doses for the newer atypical antipsychotics. Journal of Clinical Psychiatry 2003, 64:663-667.
38. Zimmerman M.E., Pan J.W., Hetherington H.P., Katz M.J., Verghese J., Buschke H., et al. Hippocampal neurochemistry, neuromorphometry, and verbal memory in nondemented older adults. Neurology 2008, 70:1594-1600.