Polysaccharide biosynthesis protein CapD is a novel pathogenicity-associated determinant of Haemophilus parasuis involved in serum-resistance ability

Veterinary Microbiology

Volumn 164, Issue 1-2, 2013, Pages 184-189

  Wang, Xiangru ^a   Xu, Xiaojuan ^a   Wu, Yucong ^a   Li, Lanying ^a   Cao, Ruijuan ^a   Cai, Xuwang ^a   Chen, Huanchun ^a  

^a HUAZHONG AGRICULTURAL UNIVERSITY   (China)

Author keywords

Haemophilus parasuis; Pathogenicity; Polysaccharide biosynthesis protein; Serum resistance

Indexed keywords

CAPD PROTEIN; POLYSACCHARIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBIOTIC RESISTANCE; ARTICLE; ASCITES; AUTOPSY; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CAPD GENE; CARBOHYDRATE SYNTHESIS; DELETION MUTANT; DISEASE ASSOCIATION; GENE; GENE DELETION; GENETIC COMPLEMENTATION; HAEMOPHILUS PARASUIS; HYDROTHORAX; NONHUMAN; PATHOGENICITY; PIGLET; PLEURISY; RESPIRATORY DISTRESS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BACTERIAL PROTEINS; ESCHERICHIA COLI; GENE DELETION; HAEMOPHILUS INFECTIONS; HAEMOPHILUS PARASUIS; RANDOM ALLOCATION; SWINE; SWINE DISEASES;

HAEMOPHILUS PARASUIS;

EID: 84875856065     PISSN: 03781135     EISSN: 18732542     Source Type: Journal    
DOI: 10.1016/j.vetmic.2013.01.037     Document Type: Article

References (8)

1. Cai X., Chen H., Blackall P.J., Yin Z., Wang L., Liu Z., Jin M. Serological characterization of Haemophilus parasuis isolates from China. Vet. Microbiol. 2005, 111:231-236.
2. Chen L., Wu D., Cai X., Guo F., Blackall P.J., Xu X., Chen H. Electrotransformation of Haemophilus parasuis with in vitro modified DNA based on a novel shuttle vector. Vet. Microbiol. 2012, 155:310-316.
3. Donahue J.P., Israel D.A., Peek R.M., Blaser M.J., Miller G.G. Overcoming the restriction barrier to plasmid transformation of Helicobacter pylori. Mol. Microbiol. 2000, 37:1066-1074.
4. Oliveira S., Pijoan C. Haemophilus parasuis: new trends on diagnosis, epidemiology and control. Vet. Microbiol. 2004, 99:1-12.
5. Tatum F.M., Briggs R.E. Construction of in-frame aroA deletion mutants of Mannheimia haemolytica, Pasteurella multocida, and Haemophilus somnus by using a new temperature-sensitive plasmid. Appl. Environ. Microbiol. 2005, 71:7196-7202.
6. Xu Z., Yue M., Zhou R., Jin Q., Fan Y., Bei W., Chen H. Genomic characterization of Haemophilus parasuis SH0165, a highly virulent strain of serovar 5 prevalent in China. PLoS One 2011, 6:e19631.
7. Zhang B., He Y., Xu C., Xu L., Feng S., Liao M., Ren T. Cytolethal distending toxin (CDT) of the Haemophilus parasuis SC096 strain contributes to serum resistance and adherence to and invasion of PK-15 and PUVEC cells. Vet. Microbiol. 2012, 157:237-242.
8. Zhou H., Yang B., Xu F., Chen X., Wang J., Blackall P.J., Zhang P., Xia Y., Zhang J., Ma R. Identification of putative virulence-associated genes of Haemophilus parasuis through suppression subtractive hybridization. Vet. Microbiol. 2010, 144:377-383.