Cytoskeletal changes during development and aging in the cortex of neurofilament light protein knockout mice

Journal of Comparative Neurology

Volumn 521, Issue 8, 2013, Pages 1817-1827

  Liu, Yao ^a   Staal, Jerome A ^b   Canty, Alison J ^c   Kirkcaldie, Matthew T K ^c   King, Anna E ^a   Bibari, Olivier ^a   Mitew, Stan T ^b   Dickson, Tracey C ^b   Vickers, James C ^a,c  

^a Wicking Dementia Research and Education Centre   (Australia)

^b UNIVERSITY OF TASMANIA   (Australia)

^c UNIVERSITY OF TASMANIA   (Australia)

Author keywords

Cytoskeletal protein; Interneuron; Neurofilament; Pyramidal neurons

Indexed keywords

ALPHA INTERNEXIN; BETA ACTIN; BETA TUBULIN; CALRETININ; CYTOSKELETON PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 2; NEUROFILAMENT LIGHT PROTEIN; NEUROFILAMENT PROTEIN; UNCLASSIFIED DRUG;

AGE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN NERVE CELL; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; INTERNEURON; KNOCKOUT MOUSE; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEPHOSPHORYLATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PYRAMIDAL NERVE CELL;

AGING; ANALYSIS OF VARIANCE; ANIMALS; CEREBRAL CORTEX; CYTOSKELETAL PROTEINS; CYTOSKELETON; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEUROFILAMENT PROTEINS; NEURONS;

EID: 84875852008     PISSN: 00219967     EISSN: 10969861     Source Type: Journal    
DOI: 10.1002/cne.23261     Document Type: Article

References (39)

1. Benson DL, Mandell JW, Shaw G, Banker G. 1996. Compartmentation of alpha internexin and neurofilament triplet proteins in cultured hippocampal neurons. J Neurocytol 25: 181-196.
2. Blizzard CA, Chuckowree JA, King AE Hosie KA, McCormack GH, Chapman JA, Vickers JC, Dickson TC. 2011. Focal damage to the adult rat neocortex induces wound healing accompanied by axonal sprouting and dendritic structural plasticity. Cereb Cortex 21: 281-291.
3. Camp AJ, Wijesinghe R. 2009. Calretinin: modulator of neuronal excitability. Int J Biochem Cell Biol 41: 2118-2121.
4. Carter JE, Robertson J, Anderton BH, Gallo JM. 1997. Incorporation of NF-L into keratin filaments in transfected epithelial cells. Neuroreport 8: 2225-2228.
5. Conde F, Lund JS, Jacoboowitz DM, Baimbridge KG, Lewis DA. 1994. Local circuit neurons immunoreactive for calretinin, calbindin D-28k or parvalbumin in monkey prefrontal cortex: distribution and morphology. J Comp Neurol 341: 95-116.
6. DeFelipe J, Gonzalez-Albo M, Del Rio M, Elston G. 1999. Distribution and patterns of connectivity of interneuronscontaining calbindin, calretinin, and parvalbumin in visual areas of the occipital and temporal lobes of the macaque monkey. J Comp Neurol 412: 515-526.
7. Dickson TC, King CE, McCormack GH, Vickers JC. 1999. Neurochemical diversity of dystrophic neurites in the early and late stages of Alzheimer's disease. Exp Neurol. 156: 100-110.
8. Dickson TC, Chuckowree JA, Chuah MI, West AK, Vickers JC. 2005. Alpha-Internexin immunoreactivity reflects variable neuronal vulnerability in Alzheimer's disease and supports the role of the beta-amyloid plaques in inducing neuronal injury. Neurobiol Dis 18: 286-295.
9. Dubois M, Strazielle C, Julien JP, Lalonde R. 2005. Mice with the deleted neurofilament of low molecular weight (Nefl) gene: 2. Effects on motor functions and spatial orientation. J Neurosci Res 80: 751-758.
10. Evans J, Sumners C, Moore J, Huentelman MJ, Deng J, Gelband CH, Shaw G. 2002. Characterization of mitotic neurons derived from adult rat hypothalamus and brain stem. J Neurophysiol 87: 1076-1085.
11. Fan Y, Dickman KG, Zong WX. 2010. Akt and c-myc differentially activate cellular metabolic programs and prime cells to bioenergetic inhibition. J Biol Chem 285: 7324-7333.
12. Fliegner KH, Liem RK. 1991. Cellular and molecular biology of neuronal intermediate filaments. Int Rev Cytol 131: 109-167.
13. Haase D, Keiner S, Mawrin C, Wolf G. 2009. Reduced Morg1 expression in ischemic human brain. Neurosci Lett 455: 46-50.
14. Julien JP, Beaulieu JM. 2000. Cytoskeletal abnormalities in amyotrophic lateral sclerosis: beneficial or detrimental effects? J Neurol Sci 180: 7-14.
15. King AE, Chung JC, Vickers JC, Dickson TC. 2006. Localization of glutamate receptors in developing cortical neurons in culture and relationship to susceptibility to excitotoxicity. J Comp Neurol 498: 277-294.
16. Kirkcaldie MTK. 2012. Neocortex. In: Watson CR, Paxinos G, Puelles L, editors. The mouse nervous system, 1st ed. San Diego: Academic Press. p 52-111.
17. Kirkcaldie MTK, Dickson TC, King CE, Grasby D, Riederer BM, Vickers JC. 2002. Neurofilament triplet proteins are restricted to a subset of neurons in the rat neocortex. J Chem Neuroanat 24: 163-171.
18. Klugmann M, Schwab MH, Pühlhofer A, Schneider A, Zimmermann F, Griffiths IR, Nave KA. 1997. Assembly of CNS myelin in the absence of proteolipid protein. Neuron 18: 59-70.
19. Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
20. Lee MK, Cleveland DW. 1996. Neuronal intermediate filament. Annu Rev Neurosci 19: 187-217.
21. Li ZH, Lu J, Tay SS, Wu YJ, Strong MJ, He BP. 2006. Mice with targeted disruption of neurofilament light subunit display formation of protein aggregation in motoneurons and downregulation of complement receptor type 3 alpha subunit in microglia in the spinal cord at their earlier age: a possible feature in pre-clinical development of neurodegenerative diseases. Brain Res 1113: 200-209.
22. Liu SJ, Zhang JY, Li HL, Fang ZY, Wang Q, Deng HM, Gong CX, Grundke-Iqbel I, Iqbel K, Wang JZ. 2004. Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain. J Biol Chem 279: 50078-50088.
23. Matsunaga W, Miyata S, Kiyohara T. 1999. Redistribution of MAP2 immunoreactivity in the neurohypophysial astrocytes of adult rats during dehydration. Brain Res 829: 7-17.
24. Park HJ, Lee SN, Lim HR, Kong JH, Jeon CJ. 2000. Calcium-binding protein calbindin D28K, calretinin, and parvalbumin immunoreactivity in the rabbit visual cortex. Mol Cell 10: 206-212.
25. Paulussen M, Jacobs S, van der Gucht E, Hof PR, Arckens L. 2011. Cytoarchitecture of the mouse neocortex revealed by the low-molecular-weight neurofilament protein subunit. Brain Struct Funct 216: 183-199.
26. Sampson VL, Morrison JH, Vickers JC. 1997. The cellular basis for the relative resistance of parvalbumin and calretinin immunoreactive neocortical neurons to the pathology of Alzheimer's disease. Exp Neurol 145: 295-302.
27. Schwaller B, Buchwald P, Blümcke I, Celio MR, Hunziker W. 1994. Characterization of a polyclonal antiserum against the purified human recombinant calcium-binding protein calretinin. Cell Calcium 14: 639-648.
28. Staal JA, Alexander SR, Liu Y, Dickson TD, Vickers JC. 2011. Characterization of cortical neuronal and glial alterations during culture of organotypic whole brain slices from neonatal and mature mice. PLoS ONE 6: e22040.
29. Sternberger LA, Sternberger NH. 1983. Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ. Proc Natl Acad Sci U S A 80: 6126-6130.
30. Toyoshima I, Kato K, Sugawara M, Wada C, Okawa S, Kobayashi M, Masamune O, Watanabe S. 2000. Massive accumulation of M and H subunits of neurofilament proteins in spinal motor neurons of neurofilament deficient Japanese quail, Quv. Neurosci Lett 287: 175-178.
31. Van der Gucht E, Hof PR, Van Brussel L, Burnat K, Arckens L. 2007. Neurofilament protein and neuronal activity markers define regional architectonic parcellation in the mouse cortex. Cereb Cortex 17: 2805-2819.
32. Vickers JC, Costa M. 1992. The neurofilament triplet is present in distinct subpopulations of neurons in the central nervous system of the guinea-pig. Neuroscience 49: 73-100.
33. Wong NK, He BP, Strong MJ. 2000. Characterization of neuronal intermediate filament protein expression in cervical spinal motor neurons in sporadic amyotrophic lateral sclerosis (ALS). J Neuropathol Exp Neurol 59: 972-982.
34. Woodhouse A, Shepherd CE, Sokolova A, Carroll VL, King AE, Halliday GM, Dickson TC, Vickers JC. 2009. Cytoskeletal alterations differentiate presenilin-1 and sporadic Alzheimer's disease. Acta Neuropathol 117: 19-29.
35. Yamashita A, Valkova K, Gonchar Y, Burkhalter A. 2003. Rearrangement of synaptic connections with inhibitory neurons in developing mouse visual cortex. J Comp Neurol 464: 426-437.
36. Yuan A, Rao MV, Chen Y, Kumar A, Veeranna, Liem RK, Eyer J, Peterson AC, Julien JP, Nixon RA. 2006. Alpha-internexin is structurally and functionally associated with the neurofilament triplet proteins in the mature CNS. J Neurosci 26: 10006-10019.
37. Yum SW, Zhang J, Mo K, Li J, Scherer SS. 2009. A novel recessive Nefl mutation causes a severe, early-onset axonal neuropathy. Ann Neurol 66: 759-770.
38. Zhang Z, Casey DM, Julien JP, Xu Z. 2002. Normal dendritic arborization in spinal motoneurons requires neurofilament subunit L. J Comp Neurol 450: 144-152.
39. Zhu Q, Couillard-Després S, Julien JP. 1997. Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments. Exp Neurol 148: 299-316.