Histamine-2 receptor blockers alter the fecal microbiota in premature infants

Journal of Pediatric Gastroenterology and Nutrition

Volumn 56, Issue 4, 2013, Pages 397-400

  Gupta, Raegan W ^a   Tran, Lynn ^b   Norori, Johana ^c   Ferris, Michael J ^a   Eren, A Murat ^d   Taylor, Christopher M ^e   Dowd, Scot E ^f   Penn, Duna ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Baton Rouge General   (United States)

^c CHILDREN S HOSPITAL   (United States)

^d MARINE BIOLOGICAL LABORATORY   (United States)

^e USA   (United States)

^f MR DNA Molecular Research LP   (United States)

Author keywords

fecal microbiota; H2 blockers; necrotizing enterocolitis; premature infants

Indexed keywords

RANITIDINE; RNA 16S;

ARTICLE; BACTERIAL COLONIZATION; COLON FLORA; CONTROLLED STUDY; DNA EXTRACTION; ENTEROBACTERIACEAE; FECES ANALYSIS; FECES MICROFLORA; FEMALE; FIRMICUTES; GENE AMPLIFICATION; GESTATIONAL AGE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MICROBIAL COMMUNITY; MICROBIAL DIVERSITY; MOLECULAR BIOLOGY; NEWBORN; POLYMERASE CHAIN REACTION; PREMATURITY; PRIORITY JOURNAL; PROTEOBACTERIA; PYROSEQUENCING;

BACTERIA (MICROORGANISMS); ENTEROBACTERIACEAE; FIRMICUTES; PROTEOBACTERIA;

EID: 84875820195     PISSN: 02772116     EISSN: 15364801     Source Type: Journal    
DOI: 10.1097/MPG.0b013e318282a8c2     Document Type: Article

References (32)

1. Fitzgibbons SC, Ching Y, Yu D, et al. Mortality of necrotizing enter-ocolitis expressed by birth weight categories. J Pediatr Surg 2009; 44:1072-5.
2. Hunter CJ, Upperman JS, Ford HR, et al. Understanding the susceptibility of the premature infant to necrotizing enterocolitis (NEC). Pediatr Res 2008;63:117-23.
3. Neu J, Walker WA. Necrotizing enterocolitis. N Engl J Med 2011; 364:255-64.
4. Palmer C, Bik EM, DiGiulio DB, et al. Development of the human infant intestinal microbiota. PLoS Biol 2007;5:e177.
5. Wang Y, Hoenig JD, Malin KJ, et al. 16S rRNA gene-based analysis of fecal microbiota from preterm infants with and without necrotizing enterocolitis. Isme J 2009;3:944-54.
6. Mai V, Young CM, Ukhanova M, et al. Fecal microbiota in premature infants prior to necrotizing enterocolitis. PLoS One 2011;6:e20647.
7. Bergholz TM, Whittam TS. Variation in acid resistance among enter-ohaemorrhagic Escherichia coli in a simulated gastric environment. J Appl Microbiol 2007;102:352-62.
8. Wilson M. The gastrointestinal tract and its indigenous microbiota. In: Microbial Inhabitants of Humans: Their Ecology and Role in Health and Disease. London: Cambridge University Press; 2005:278-282.
9. Iseki K. [Development of intestinal flora in neonates]. Hokkaido Igaku Zasshi 1987;62:895-906.
10. Bullen JJ. Iron-binding proteins and other factors in milk responsible for resistance to Escherichia coli. Ciba Found Symp 1976;(42):149-69.
11. Carrion V, Egan EA. Prevention of neonatal necrotizing enterocolitis. J Pediatr Gastroenterol Nutr 1990;11:317-23.
12. Guillet R, Stoll BJ, Cotten CM, et al. Association of H2-blocker therapy and higher incidence of necrotizing enterocolitis in very low birth weight infants. Pediatrics 2006;117:e137-42.
13. Terrin G, Passariello A, De Curtis M, et al. Ranitidine is associated with infections, necrotizing enterocolitis, and fatal outcome in newborns. Pediatrics 2012;129:e40-5.
14. Caporaso JG, Kuczynski J, Stombaugh J, et al. QIIME allows analysis of high-throughput community sequencing data. Nat Methods 2010;7: 335-6.
15. Edgar RC. Search and clustering orders of magnitude faster than BLAST. Bioinformatics 2010;26:2460-1.
16. Caporaso JG, Bittinger K, Bushman FD, et al. PyNAST: a flexible tool for aligning sequences to a template alignment. Bioinformatics 2010; 26:266-7.
17. DeSantis TZ, Hugenholtz P, Larsen N, et al. Greengenes, a chimera-checked 16S rRNA gene database and workbench compatible with ARB. Appl Environ Microbiol 2006;72:5069-72.
18. Wang Q, Garrity GM, Tiedje JM, et al. Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy. Appl Environ Microbiol 2007;73:5261-7.
19. Price MN, Dehal PS, Arkin AP. FastTree 2-approximately maximum-likelihood trees for large alignments. PLoS One 2010;5:e9490.
20. Lozupone C, Knight R. UniFrac: a new phylogenetic method for comparing microbial communities. Appl Environ Microbiol 2005;71: 8228-35.
21. O'May GA, Reynolds N, Macfarlane GT. Effect of pH on an in vitro model of gastric microbiota in enteral nutrition patients. Appl Environ Microbiol 2005;71:4777-83.
22. Kelly EJ, Newell SJ, Brownlee KG, et al. Gastric acid secretion in preterm infants. Early Hum Dev 1993;35:215-20.
23. Hyman PE, Clarke DD, Everett SL, et al. Gastric acid secretory function in preterm infants. J Pediatr 1985;106:467-71.
24. Kuusela AL. Long-term gastric pH monitoring for determining optimal dose of ranitidine for critically ill preterm and term neonates. Arch Dis Child Fetal Neonatal Ed 1998;78:F151-3.
25. Joseph S, Forsythe SJ. Predominance of Cronobacter sakazakii sequence type 4 in neonatal infections. Emerg Infect Dis 2011;17: 1713-5.
26. Pagotto FJ, Nazarowec-White M, Bidawid S, et al. Enterobacter saka-zakii: infectivity and enterotoxin production in vitro and in vivo. J Food Prot 2003;66:370-5.
27. Oelschlaeger TA, Dobrindt U, Hacker J. Virulence factors of uropatho-gens. Curr Opin Urol 2002;12:33-8.
28. Korhonen TK, Valtonen MV, Parkkinen J, et al. Serotypes, hemolysin production, and receptor recognition of Escherichia coli strains associated with neonatal sepsis and meningitis. Infect Immun 1985;48:486-91.
29. Hallet B. Playing Dr Jekyll and Mr Hyde: combined mechanisms of phase variation in bacteria. Curr Opin Microbiol 2001;4:570-81.
30. Young GM, Schmiel DH, Miller VL. A new pathway for the secretion of virulence factors by bacteria: the flagellar export apparatus functions as a protein-secretion system. Proc Natl Acad Sci USA 1999;96:6456-61.
31. Hansen LH, Bentzon-Tilia M, Bentzon-Tilia S, et al. Design and synthesis of a quintessential self-transmissible IncX1 plasmid, pX1.0. PLoS One 2011;6:e19912.
32. Boccia D, Stolfi I, Lana S, et al. Nosocomial necrotising enterocolitis outbreaks: epidemiology and control measures. Eur J Pediatr 2001; 160:385-91.