Intratumoral injection of attenuated Salmonella vaccine can induce tumor microenvironmental shift from immune suppressive to immunogenic

Vaccine

Volumn 31, Issue 10, 2013, Pages 1377-1384

  Hong, Eun Hye ^a   Chang, Sun Young ^b   Lee, Bo Ra ^a   Pyun, A Rim ^a   Kim, Ji Won ^a   Kweon, Mi Na ^c   Ko, Hyun Jeong ^a  

^a Kangwon National University   (South Korea)

^b Ajou University   (South Korea)

^c International Vaccine Institute   (South Korea)

Author keywords

CTL; MDSC; Salmonella; Treg; Tumor

Indexed keywords

CANCER VACCINE; CD11B ANTIGEN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GEMCITABINE; RECOMBINANT ATTENUATED SALMONELLA ENTERICA VACCINE; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOTRANSFORMATION; BONE MARROW CELL; CANCER GROWTH; CD4+ CD25+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; COLON CARCINOMA; COLONY FORMING UNIT; COMPETITIVE INHIBITION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; IMMUNE RESPONSE; IMMUNOGENICITY; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SALMONELLA ENTERICA; TUMOR MICROENVIRONMENT;

ANIMALS; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; HUMANS; IMMUNOLOGIC FACTORS; INJECTIONS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEOPLASMS; SALMONELLA TYPHIMURIUM; SALMONELLA VACCINES; T-LYMPHOCYTE SUBSETS; VACCINATION; VACCINES, ATTENUATED; VACCINES, SYNTHETIC;

EID: 84875806673     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2013.01.006     Document Type: Article

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