Biochemical and hematologic effects of polyvinylpyrrolidone-wrapped fullerene C60 after oral administration

Pharmazie

Volumn 68, Issue 1, 2013, Pages 54-57

  Yamashita, K ^a   Yoshioka, Y ^a   Pan, H ^a   Taira, M ^a   Ogura, T ^a   Nagano, T ^a   Aoyama, M ^a   Nagano, K ^b   Abe, Y ^c   Kamada, H ^a,b   Tsunoda, S I ^a,b   Aoshima, H ^d   Nabeshi, H ^e   Yoshikawa, T ^a   Tsutsumi, Y ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^c SANFORD RESEARCH   (United States)

^d Vitamin C60 BioResearch Corporation   (Japan)

^e NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FULLERENE C60; FULLERENE DERIVATIVE; POVIDONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON; CONTROLLED STUDY; FEMALE; KIDNEY INJURY; LIVER INJURY; MOUSE; NONHUMAN; ACUTE KIDNEY FAILURE; ANIMAL; BLOOD CELL COUNT; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; COLITIS; LIGHT; ORAL DRUG ADMINISTRATION; PATHOLOGY; RADIATION SCATTERING; TISSUE FIXATION; TOXIC HEPATITIS;

ACUTE KIDNEY INJURY; ADMINISTRATION, ORAL; ANIMALS; BLOOD CELL COUNT; COLITIS; DRUG-INDUCED LIVER INJURY; FEMALE; FULLERENES; LIGHT; MICE; MICE, INBRED C57BL; POVIDONE; SCATTERING, RADIATION; TISSUE FIXATION;

MLCS; MLOWN;

EID: 84875770236     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2013.2708     Document Type: Article

References (26)

1. Aoshima H, Kokubo K, Shirakawa S, Ito M, Yamana S, Oshima T (2009) Antimicrobial activity of fullerenes and their hydroxylated derivatives. Biocontrol Sci 14: 69-72.
2. Aoshima H, Yamana S, Nakamura S, Mashino T (2010) Biological safety of water-soluble fullerenes evaluated using tests for genotoxicity, phototoxicity, and pro-oxidant activity. J Toxicol Sci 35: 401-409.
3. Augustin MA, Sanguansri P (2009) Nanostructured materials in the food industry. Adv Food Nutr Res 58: 183-213.
4. Benn TM,Westerhoff P, Herckes P (2011) Detection of fullerenes (C60 and C70) in commercial cosmetics. Environ Pollut 159: 1334-1342.
5. Bimbo LM, Sarparanta M, Santos HA, Airaksinen AJ, Makila E, Laaksonen T, Peltonen L, Lehto VP, Hirvonen J, Salonen J (2010) Biocompatibility of thermally hydrocarbonized porous silicon nanoparticles and their biodistribution in rats. ACS Nano 4: 3023-3032.
6. Bowman DM, van Calster G, Friedrichs S (2010) Nanomaterials and regulation of cosmetics. Nat Nanotechnol 5: 92.
7. Chen Z, Ma L, Liu Y, Chen C (2012) Applications of functionalized fullerenes in tumor theranostics. Theranostics 2: 238-250.
8. Ema M, Tanaka J, Kobayashi N, Naya M, Endoh S, Maru J, Hosoi M, Nagai M, Nakajima M, Hayashi M, Nakanishi J (2012) Genotoxicity evaluation of fullerene C60 nanoparticles in a comet assay using lung cells of intratracheally instilled rats. Regul Toxicol Pharmacol 62: 419-424.
9. Gharbi N, Pressac M, Hadchouel M, Szwarc H,Wilson SR, Moussa F (2005) [60]fullerene is a powerful antioxidant in vivo with no acute or subacute toxicity. Nano Lett 5: 2578-2585.
10. Hu Z, Liu S,Wei Y, Tong E, Cao F, GuanW(2007) Synthesis of glutathione C60 derivative and its protective effect on hydrogen peroxide-induced apoptosis in rat pheochromocytoma cells. Neurosci Lett 429: 81-86.
11. Kato S, Aoshima H, Saitoh Y, Miwa N (2009) Biological safety of Lipo-Fullerene composed of squalane and fullerene-C60 upon mutagenesis, photocytotoxicity, and permeability into the human skin tissue. Basic Clin Pharmacol Toxicol 104: 483-487.
12. Kato S, Taira H, Aoshima H, SaitohY, MiwaN(2010) Clinical evaluation of fullerene-C60 dissolved in squalane for anti-wrinkle cosmetics. J Nanosci Nanotechnol 10: 6769-6774.
13. Kokubo K, Tochika S, Kato M, SolY, Oshima T (2008) AlCl3-catalyzed tandem acetylation of hydroarylated [60]fullerenes. Org Lett 10: 3335-3338.
14. Konstantatos G, Sargent EH (2010) Nano structured materials for photon detection. Nat Nanotechnol 5: 391-400.
15. Krusic PJ,Wasserman E, Keizer PN, Morton JR, Preston KF (1991) Radical reactions of c60. Science 254: 1183-1185.
16. Lin CM, Lu TY (2012) C60 Fullerene Derivatized Nanoparticles and their Application to Therapeutics. Recent Pat Nanotechnol 6: 105-113.
17. Metanawin T, Tang T, Chen R, Vernon D, Wang X (2011) Cytotoxicity and photocytotoxicity of structure-defined water-soluble C60/micelle supramolecular nanoparticles. Nanotechnology 22: 235604.
18. Nielsen GD, Roursgaard M, Jensen KA, Poulsen SS, Larsen ST (2008) In vivo biology and toxicology of fullerenes and their derivatives. Basic Clin Pharmacol Toxicol 103: 197-208.
19. Petros RA, DeSimone JM (2010) Strategies in the design of nanoparticles for therapeutic applications. Nat Rev Drug Discov 9: 615-627.
20. Shinohara N, Matsumoto K, Endoh S, Maru J, Nakanishi J (2009) In vitro and in vivo genotoxicity tests on fullerene C60 nanoparticles. Toxicol Lett 191: 289-296.
21. Xiao L, Matsubayashi K, Miwa N (2007) Inhibitory effect of the water-soluble polymer-wrapped derivative of fullerene on UVA-induced melanogenesis via downregulation of tyrosinase expression in human melanocytes and skin tissues. Arch Dermatol Res 299: 245-257.
22. Yamago S, Tokuyama H, Nakamura E, Kikuchi K, Kananishi S, Sueki K, Nakahara H, Enomoto S, Ambe F (1995) In vivo biological behavior of a water-miscible fullerene: 14C labeling, absorption, distribution, excretion and acute toxicity. Chem Biol 2: 385-389.
23. Yin JJ, Lao F, Fu PP, Wamer WG, Zhao Y, Wang PC, Qiu Y, Sun B, Xing G, Dong J, Liang XJ, Chen C (2009) The scavenging of reactive oxygen species and the potential for cell protection by functionalized fullerene materials. Biomaterials 30: 611-621.
24. Yudoh K, Karasawa R, Masuko K, Kato T (2009a) Water-soluble fullerene (C60) inhibits the development of arthritis in the rat model of arthritis. Int J Nanomedicine 4: 217-225.
25. Yudoh K, Karasawa R, Masuko K, Kato T (2009b) Water-soluble fullerene (C60) inhibits the osteoclast differentiation and bone destruction in arthritis. Int J Nanomedicine 4: 233-239.
26. Zhang LW, Yang J, Barron AR, Monteiro-Riviere NA (2009) Endocytic mechanisms and toxicity of a functionalized fullerene in human cells. Toxicol Lett 191: 149-157.