-
1
-
-
77950930674
-
Simple and selective method for the determination of various tyrosine kinase inhibitors used in the clinical setting by liquid chromatography tandem mass spectrometry
-
Honeywell R, Yarzadah K, Giovannetti E, et al: Simple and selective method for the determination of various tyrosine kinase inhibitors used in the clinical setting by liquid chromatography tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 878:1059-1068, 2010
-
(2010)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.878
, pp. 1059-1068
-
-
Honeywell, R.1
Yarzadah, K.2
Giovannetti, E.3
-
2
-
-
78649727711
-
The therapy of kidney cancer with biomolecular drugs
-
Di Lorenzo G, Buonerba C, Biglietto M, et al: The therapy of kidney cancer with biomolecular drugs. Cancer Treat Rev 36:S16-S20, 2010 (suppl 3)
-
(2010)
Cancer Treat Rev
, vol.36
, Issue.SUPPL. 3
-
-
Di Lorenzo, G.1
Buonerba, C.2
Biglietto, M.3
-
3
-
-
12244301581
-
In vivo antitumor activity of su11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/ pharmacodynamic relationship
-
Mendel DB, Laird AD, Xin X, et al: In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/ pharmacodynamic relationship. Clin Cancer Res 9:327-337, 2003
-
(2003)
Clin Cancer Res
, vol.9
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
-
4
-
-
33644847440
-
Safety, pharmacokinetic, and antitumor activity of su11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer
-
Faivre S, Delbaldo C, Vera K, et al: Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer. J Clin Oncol 24:25-35, 2006
-
(2006)
J Clin Oncol
, vol.24
, pp. 25-35
-
-
Faivre, S.1
Delbaldo, C.2
Vera, K.3
-
5
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
Motzer RJ, Hutson TE, Tomczak P, et al: Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 356:115-124, 2007
-
(2007)
N Engl J Med
, vol.356
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
-
6
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
Escudier B, Eisen T, Stadler WM, et al: Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 356:125-134, 2007
-
(2007)
N Engl J Med
, vol.356
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
-
7
-
-
84875735553
-
-
Pfizer: Summary of product characteristics: Sutent (sunitinib).
-
Pfizer: Summary of product characteristics: Sutent (sunitinib). http://www- .medicines.org.uk/emc/medicine/18531/SPC
-
-
-
-
9
-
-
59649129538
-
Sunitinib (sutent, su11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the atpbinding cassette (abc) transporters p-glycoprotein (abcb1) and abcg2
-
Shukla S, Robey RW, Bates SE, et al: Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATPbinding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2. Drug Metab Dispos 37:359-365, 2009
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 359-365
-
-
Shukla, S.1
Robey, R.W.2
Bates, S.E.3
-
10
-
-
67651172794
-
Abcg2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin
-
Keskitalo JE, Zolk O, Fromm MF, et al: ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin. Clin Pharmacol Ther 86:197-203, 2009
-
(2009)
Clin Pharmacol Ther
, vol.86
, pp. 197-203
-
-
Keskitalo, J.E.1
Zolk, O.2
Fromm, M.F.3
-
11
-
-
77953967726
-
Abcg2 421ca polymorphism and high exposure of sunitinib in a patient with renal cell carcinoma
-
Mizuno T, Terada T, Kamba T, et al: ABCG2 421CA polymorphism and high exposure of sunitinib in a patient with renal cell carcinoma. Ann Oncol 21:1382- 1383, 2010
-
(2010)
Ann Oncol
, vol.21
, pp. 1382-1383
-
-
Mizuno, T.1
Terada, T.2
Kamba, T.3
-
12
-
-
41949140593
-
Pharmacogenomic and pharmacokinetic determinants of erlotinib toxicity
-
Rudin CM, Liu W, Desai A, et al: Pharmacogenomic and pharmacokinetic determinants of erlotinib toxicity. J Clin Oncol 26:1119-1127, 2008
-
(2008)
J Clin Oncol
, vol.26
, pp. 1119-1127
-
-
Rudin, C.M.1
Liu, W.2
Desai, A.3
-
13
-
-
40549099027
-
Common atp-binding cassette b1 variants are associated with increased digoxin serum concentration
-
Aarnoudse AJ, Dieleman JP, Visser LE, et al: Common ATP-binding cassette B1 variants are associated with increased digoxin serum concentration. Pharmacogenet Genomics 18:299-305, 2008
-
(2008)
Pharmacogenet Genomics
, vol.18
, pp. 299-305
-
-
Aarnoudse, A.J.1
Dieleman, J.P.2
Visser, L.E.3
-
14
-
-
34248140167
-
Dose-dependent effects of the 3435 ct genotype of abcb1 gene on the steady-state plasma concentration of fluvoxamine in psychiatric patients
-
Fukui N, Suzuki Y, Sawamura K, et al: Dose-dependent effects of the 3435 CT genotype of ABCB1 gene on the steady-state plasma concentration of fluvoxamine in psychiatric patients. Ther Drug Monit 29:185-189, 2007
-
(2007)
Ther Drug Monit
, vol.29
, pp. 185-189
-
-
Fukui, N.1
Suzuki, Y.2
Sawamura, K.3
-
15
-
-
37349034567
-
Cyp2b6 genetic variants are associated with nevirapine pharmacokinetics and clinical response in hiv-1- infected children
-
Saitoh A, Sarles E, Capparelli E, et al: CYP2B6 genetic variants are associated with nevirapine pharmacokinetics and clinical response in HIV-1- infected children. AIDS 21:2191-2199, 2007
-
(2007)
AIDS
, vol.21
, pp. 2191-2199
-
-
Saitoh, A.1
Sarles, E.2
Capparelli, E.3
-
16
-
-
33749267293
-
Role of pharmacogenetics of atp-binding cassette transporters in the pharmacokinetics of drugs
-
Cascorbi I: Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs. Pharmacol Ther 112:457-473, 2006
-
(2006)
Pharmacol Ther
, vol.112
, pp. 457-473
-
-
Cascorbi, I.1
-
17
-
-
79551701442
-
Genetic polymorphisms associated with a prolonged progression-free survival in patients with metastatic renal cell cancer treated with sunitinib
-
van der Veldt AA, Eechoute K, Gelderblom H, et al: Genetic polymorphisms associated with a prolonged progression-free survival in patients with metastatic renal cell cancer treated with sunitinib. Clin Cancer Res 17:620- 629, 2011
-
(2011)
Clin Cancer Res
, vol.17
, pp. 620-629
-
-
Van Der Veldt, A.A.1
Eechoute, K.2
Gelderblom, H.3
-
18
-
-
70349342710
-
Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity
-
van Erp NP, Eechoute K, van der Veldt AA, et al: Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity. J Clin Oncol 27:4406- 4412, 2009
-
(2009)
J Clin Oncol
, vol.27
, pp. 4406-4412
-
-
Van Erp, N.P.1
Eechoute, K.2
Van Der Veldt, A.A.3
-
19
-
-
0023447098
-
Cellular localization of the multidrugresistance gene product p-glycoprotein in normal human tissues
-
Thiebaut F, Tsuruo T, Hamada H, et al: Cellular localization of the multidrugresistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci U S A 84:7735-7738, 1987
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
-
20
-
-
82555189379
-
Lysosomal sequestration of sunitinib: A novel mechanism of drug resistance
-
Gotink KJ, Broxterman HJ, Labots M, et al: Lysosomal sequestration of sunitinib: A novel mechanism of drug resistance. Clin Cancer Res 17:7337-7346, 2011
-
(2011)
Clin Cancer Res
, vol.17
, pp. 7337-7346
-
-
Gotink, K.J.1
Broxterman, H.J.2
Labots, M.3
-
21
-
-
19744365702
-
A small molecule-kinase interaction map for clinical kinase inhibitors
-
Fabian MA, Biggs WH 3rd, Treiber DK, et al: A small molecule-kinase interaction map for clinical kinase inhibitors. Nat Biotechnol 23:329-336, 2005
-
(2005)
Nat Biotechnol
, vol.23
, pp. 329-336
-
-
Fabian, M.A.1
Biggs III, W.H.2
Treiber, D.K.3
|