메뉴 건너뛰기




Volumn 49, Issue 2, 2013, Pages 369-379

Effects of erythropoietin on blood-brain barrier tight junctions in ischemia-reperfusion rats

Author keywords

Blood brain barrier; Cerebral ischemia reperfusion; NF kB; rhEPO; Tight junction; TNF

Indexed keywords

BETA ACTIN; CLAUDIN 5; EVANS BLUE; MESSENGER RNA; OCCLUDIN; PROTEIN ZO1; RECOMBINANT ERYTHROPOIETIN; SODIUM CHLORIDE; TRANSCRIPTION FACTOR RELA; TRIPHENYLTETRAZOLIUM; TUMOR NECROSIS FACTOR ALPHA;

EID: 84875754299     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9883-5     Document Type: Article
Times cited : (33)

References (37)
  • 1
    • 84855447337 scopus 로고    scopus 로고
    • TNF-alpha induced NFκB signaling and p65 (RelA) overexpression repress Cldn5 promoter in mouse brain endothelial cells
    • 22138107 10.1016/j.cyto.2011.10.016 1:CAS:528:DC%2BC38XlsVKqtw%3D%3D
    • Aslam M, Ahmad N, Srivastava R, Hemmer B (2012) TNF-alpha induced NFκB signaling and p65 (RelA) overexpression repress Cldn5 promoter in mouse brain endothelial cells. Cytokine 57(2):269-275
    • (2012) Cytokine , vol.57 , Issue.2 , pp. 269-275
    • Aslam, M.1    Ahmad, N.2    Srivastava, R.3    Hemmer, B.4
  • 2
    • 33847247310 scopus 로고    scopus 로고
    • The relationship between erythropoietin pretreatment with blood-brain barrier and lipid peroxidation after ischemia/reperfusion in rats
    • 10.1016/j.lfs.2006.12.014
    • Bachekapili N, Uzum G, Gokkusu C, Kuru A, Ziylan YZ (2007) The relationship between erythropoietin pretreatment with blood-brain barrier and lipid peroxidation after ischemia/reperfusion in rats. Life Sci 80(14):1245-1251
    • (2007) Life Sci , vol.80 , Issue.14 , pp. 1245-1251
    • Bachekapili, N.1    Uzum, G.2    Gokkusu, C.3    Kuru, A.4    Ziylan, Y.Z.5
  • 4
    • 0029049342 scopus 로고
    • Isolation and culture of human brain microvessel endothelial cells for the study of blood-brain barrier properties in vitro
    • 8548302 10.1016/0006-8993(95)00511-N 1:CAS:528:DyaK2MXot1yrsbs%3D
    • Biegel D, Spencer DD, Pachter JS (1995) Isolation and culture of human brain microvessel endothelial cells for the study of blood-brain barrier properties in vitro. Brain Res 692(1-2):183-189
    • (1995) Brain Res , vol.692 , Issue.1-2 , pp. 183-189
    • Biegel, D.1    Spencer, D.D.2    Pachter, J.S.3
  • 5
    • 33746137372 scopus 로고    scopus 로고
    • Discovering erythropoietin's extra-hematopoietic functions: Biology and clinical promise
    • DOI 10.1038/sj.ki.5001546, PII 5001546
    • Brines M, Cerami A (2006) Discovering erythropoietin's extra-hematopoietic functions: biology and clinical promise. Kidney Int 70(2):246-250 (Pubitemid 44086573)
    • (2006) Kidney International , vol.70 , Issue.2 , pp. 246-250
    • Brines, M.1    Cerami, A.2
  • 8
    • 70450263474 scopus 로고    scopus 로고
    • Cellular elements of the blood-brain barrier
    • 19856206 10.1007/s11064-009-0081-y 1:CAS:528:DC%2BD1MXhtlSkurjJ
    • Correale J, Villa A (2009) Cellular elements of the blood-brain barrier. Neurochem Res 34(12):2067-2077
    • (2009) Neurochem Res , vol.34 , Issue.12 , pp. 2067-2077
    • Correale, J.1    Villa, A.2
  • 9
    • 0028390146 scopus 로고
    • Microvascular changes during cerebral ischemia and reperfusion
    • 8186069
    • del Zoppo GJ (1994) Microvascular changes during cerebral ischemia and reperfusion. Cerebrovasc Brain Metab Rev 6(1):47-96
    • (1994) Cerebrovasc Brain Metab Rev , vol.6 , Issue.1 , pp. 47-96
    • Del Zoppo, G.J.1
  • 10
    • 0029914446 scopus 로고    scopus 로고
    • 'Malignant' middle cerebral artery territory infarction: Clinical course and prognostic signs
    • Hacke W, Schwab S, Horn M, Spranger M, De Georgia M, von Kummer R (1996) Malignant middle cerebral artery territory infarction: clinical course and prognostic signs. Arch Neurol 53(4):309-315 (Pubitemid 26110085)
    • (1996) Archives of Neurology , vol.53 , Issue.4 , pp. 309-315
    • Hacke, W.1    Schwab, S.2    Horn, M.3    Spranger, M.4    De Georgia, M.5    Von Kummer, R.6
  • 11
    • 33646846617 scopus 로고    scopus 로고
    • The brain erythropoietin system and its potential for therapeutic exploitation in brain disease
    • DOI 10.1097/00008506-200604000-00007, PII 0000850620060400000007
    • Hasselblatt M, Ehrenreich H, Siren AL (2006) The brain erythropoietin system and its potential for therapeutic exploitation in brain disease. J Neurosurg Anesthesiol 18(2):132-138 (Pubitemid 44510112)
    • (2006) Journal of Neurosurgical Anesthesiology , vol.18 , Issue.2 , pp. 132-138
    • Hasselblatt, M.1    Ehrenreich, H.2    Siren, A.-L.3
  • 12
    • 0027760815 scopus 로고
    • Ischemia-mediated neuronal injury
    • DOI 10.1016/0300-9572(93)90143-E
    • Hossmann KA (1993) Ischemia-mediated neuronal injury. Resuscitation 26(3):225-235 (Pubitemid 24009827)
    • (1993) Resuscitation , vol.26 , Issue.3 , pp. 225-235
    • Hossmann, K.-A.1
  • 14
    • 33846963814 scopus 로고    scopus 로고
    • Erythropoietin after a century of research: Younger than ever
    • 17253966 10.1111/j.1600-0609.2007.00818.x 1:CAS:528:DC%2BD2sXjvFOitLc%3D
    • Jelkmann W (2007) Erythropoietin after a century of research: younger than ever. Eur J Haematol 78(3):183-205
    • (2007) Eur J Haematol , vol.78 , Issue.3 , pp. 183-205
    • Jelkmann, W.1
  • 15
    • 79955922988 scopus 로고    scopus 로고
    • Specific role of tight junction proteins claudin-5, occludin, and ZO-1 of the blood-brain barrier in a focal cerebral ischemic insult
    • 21318404 10.1007/s12031-011-9496-4 1:CAS:528:DC%2BC3MXlsVWit7g%3D
    • Jiao HX, Wang ZH, Liu YH, Wang P, Xue YX (2011) Specific role of tight junction proteins claudin-5, occludin, and ZO-1 of the blood-brain barrier in a focal cerebral ischemic insult. J Mol Neurosci 44(2):130-139
    • (2011) J Mol Neurosci , vol.44 , Issue.2 , pp. 130-139
    • Jiao, H.X.1    Wang, Z.H.2    Liu, Y.H.3    Wang, P.4    Xue, Y.X.5
  • 16
    • 0035914398 scopus 로고    scopus 로고
    • Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia
    • 11504731 10.1074/jbc.M105832200 1:CAS:528:DC%2BD3MXnvVemt7Y%3D
    • Kawakami M, Sekiguchi M, Sato K, Kozak S, Takahashi M (2001) Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia. J Biol Chem 276(42):39469-39475
    • (2001) J Biol Chem , vol.276 , Issue.42 , pp. 39469-39475
    • Kawakami, M.1    Sekiguchi, M.2    Sato, K.3    Kozak, S.4    Takahashi, M.5
  • 17
    • 33645580435 scopus 로고    scopus 로고
    • Erythropoietin downregulates bax and DP5 proapoptotic gene expression in neonatal hypoxic-ischemic brain injury
    • 16319448 10.1159/000089951 1:CAS:528:DC%2BD28Xjt1Clsrk%3D
    • Kumral A, Genc S, Ozer E, Yilmaz O, Gokmen N, Koroglu TF, Duman N, Genc K, Ozkan H (2006) Erythropoietin downregulates bax and DP5 proapoptotic gene expression in neonatal hypoxic-ischemic brain injury. Biol Neonate 89(3):205-210
    • (2006) Biol Neonate , vol.89 , Issue.3 , pp. 205-210
    • Kumral, A.1    Genc, S.2    Ozer, E.3    Yilmaz, O.4    Gokmen, N.5    Koroglu, T.F.6    Duman, N.7    Genc, K.8    Ozkan, H.9
  • 18
    • 26444520755 scopus 로고    scopus 로고
    • Lack of effects of 1439 MHz electromagnetic near field exposure on the blood-brain barrier in immature and young rats
    • DOI 10.1002/bem.20138
    • Kuribayashi M, Wang J, Fujiwara O, Doi Y, Nabae K, Tamano S, Ogiso T, Asamoto M, Shirai T (2005) Lack of effects of 1439 MHz electromagnetic near field exposure on the blood-brain barrier in immature and young rats. Bioelectromagnetics 26(7):578-588 (Pubitemid 41437413)
    • (2005) Bioelectromagnetics , vol.26 , Issue.7 , pp. 578-588
    • Kuribayashi, M.1    Wang, J.2    Fujiwara, O.3    Doi, Y.4    Nabae, K.5    Tamano, S.6    Ogiso, T.7    Asamoto, M.8    Shirai, T.9
  • 19
    • 0022410974 scopus 로고
    • The biphasic opening of the blood-brain barrier to proteins following temporary middle cerebral artery occlusion
    • DOI 10.1007/BF00688633
    • Kuroiwa T, Ting P, Martinez H, Klatzo I (1985) The biphasic opening of the blood-brain barrier to proteins following temporary middle cerebral artery occlusion. Acta Neuropathol 68(2):122-129 (Pubitemid 16242137)
    • (1985) Acta Neuropathologica , vol.68 , Issue.2 , pp. 122-129
    • Kuroiwa, T.1    Ting, P.2    Martinez, H.3    Klatzo, I.4
  • 20
    • 34247468355 scopus 로고    scopus 로고
    • Erythropoietin-induced neurovascular protection, angiogenesis, and cerebral blood flow restoration after focal ischemia in mice
    • DOI 10.1038/sj.jcbfm.9600417, PII 9600417
    • Li Y, Lu Z, Keogh CL, Yu SP, Wei L (2007) Erythropoietin-induced neurovascular protection, angiogenesis, and cerebral blood flow restoration after focal ischemia in mice. J Cereb Blood Flow Metab 27(5):1043-1054 (Pubitemid 46659037)
    • (2007) Journal of Cerebral Blood Flow and Metabolism , vol.27 , Issue.5 , pp. 1043-1054
    • Li, Y.1    Lu, Z.2    Keogh, C.L.3    Yu, S.P.4    Wei, L.5
  • 21
    • 85052609749 scopus 로고    scopus 로고
    • Erythropoietin attenuates intracerebral hemorrhage by diminishing matrix metalloproteinases and maintaining blood-brain barrier integrity in mice
    • 19066093 10.1007/978-3-211-09469-3-22 1:STN:280:DC%2BD1cjps1yqtg%3D%3D
    • Li Y, Ogle ME, Wallace GC 4th, Lu ZY, Yu SP, Wei L (2008) Erythropoietin attenuates intracerebral hemorrhage by diminishing matrix metalloproteinases and maintaining blood-brain barrier integrity in mice. Acta Neurochir Suppl 105:105-112
    • (2008) Acta Neurochir Suppl , vol.105 , pp. 105-112
    • Li, Y.1    Ogle, M.E.2    Wallace IV, G.C.3    Lu, Z.Y.4    Yu, S.P.5    Wei, L.6
  • 22
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • Longa EZ, Weinstein PR, Carlson S, Cummins R (1989) Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20(1):84-91 (Pubitemid 19040218)
    • (1989) Stroke , vol.20 , Issue.1 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 23
    • 1342280570 scopus 로고    scopus 로고
    • TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation
    • 14766535 10.1152/ajpgi.00173.2003 1:CAS:528:DC%2BD2cXitlSgt7w%3D
    • Ma TY, Iwamoto GK, Hoa NT, Akotia V, Pedram A, Boivin MA, Said HM (2004) TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation. Am J Physiol Gastrointest Liver Physiol 286(3):G367-G376
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.286 , Issue.3
    • Ma, T.Y.1    Iwamoto, G.K.2    Hoa, N.T.3    Akotia, V.4    Pedram, A.5    Boivin, M.A.6    Said, H.M.7
  • 24
    • 4644318784 scopus 로고    scopus 로고
    • Erythropoietin and the hypoxic brain
    • DOI 10.1242/jeb.01049
    • Marti HH (2004) Erythropoietin and the hypoxic brain. Exp Biol 207(pt 18):3233-3242 (Pubitemid 39275297)
    • (2004) Journal of Experimental Biology , vol.207 , Issue.18 , pp. 3233-3242
    • Marti, H.H.1
  • 27
    • 0033796377 scopus 로고    scopus 로고
    • Angiotensin II at (1) blockade normalizes cerebrovascular autoregulation and reduces cerebral ischemia in spontaneously hypertensive rats
    • 11022082 10.1161/01.STR.31.10.2478 1:CAS:528:DC%2BD3cXnsVKqt7w%3D
    • Nishimura Y, Ito T, Saavedra JM (2000) Angiotensin II AT (1) blockade normalizes cerebrovascular autoregulation and reduces cerebral ischemia in spontaneously hypertensive rats. Stroke 31(10):2478-2486
    • (2000) Stroke , vol.31 , Issue.10 , pp. 2478-2486
    • Nishimura, Y.1    Ito, T.2    Saavedra, J.M.3
  • 28
    • 33845400063 scopus 로고    scopus 로고
    • Exogenous expression of claudin-5 induces barrier properties in cultured rat brain capillary endothelial cells
    • DOI 10.1002/jcp.20823
    • Ohtsuki S, Sato S, Yamaguchi H, Kamio M, Asashima T, Terasaki T (2007) Exogenous expression of claudin-5 induces barrier properties in cultured rat brain capillary endothelial cells. J Cell Physiol 210(1):81-86 (Pubitemid 44904703)
    • (2007) Journal of Cellular Physiology , vol.210 , Issue.1 , pp. 81-86
    • Ohtsuki, S.1    Sato, S.2    Yamaguchi, H.3    Kamoi, M.4    Asashima, T.5    Terasaki, T.6
  • 29
    • 53749096762 scopus 로고    scopus 로고
    • Blood-brain barrier tight junction permeability and ischemic stroke
    • 18790057 10.1016/j.nbd.2008.08.005 1:CAS:528:DC%2BD1cXht1Kns7nI
    • Sandoval KE, Witt KA (2008) Blood-brain barrier tight junction permeability and ischemic stroke. Neurobiol Dis 32(2):200-219
    • (2008) Neurobiol Dis , vol.32 , Issue.2 , pp. 200-219
    • Sandoval, K.E.1    Witt, K.A.2
  • 32
    • 1542677112 scopus 로고    scopus 로고
    • Role of phosphatidylinositol 3-kinase in oxidative stress-induced disruption of tight junctions
    • 14500730 10.1074/jbc.M305654200 1:CAS:528:DC%2BD3sXptlGrsLc%3D
    • Sheth P, Basuroy S, Li C, Naren AP, Rao RK (2003) Role of phosphatidylinositol 3-kinase in oxidative stress-induced disruption of tight junctions. J Biol Chem 278(49):49239-49245
    • (2003) J Biol Chem , vol.278 , Issue.49 , pp. 49239-49245
    • Sheth, P.1    Basuroy, S.2    Li, C.3    Naren, A.P.4    Rao, R.K.5
  • 33
    • 0033956503 scopus 로고    scopus 로고
    • Neutrophil elastase inhibition reduces cerebral ischemic damage in the middle cerebral artery occlusion
    • DOI 10.1016/S0006-8993(99)02431-2, PII S0006899399024312
    • Shimakura A, Kamanaka Y, Ikeda Y, Kondo K, Suzuki Y, Umemura K (2000) Neutrophil elastase inhibition reduces cerebral ischemia damage in the middle cerebral artery occlusion. Brain Res 858(1):55-60 (Pubitemid 30105781)
    • (2000) Brain Research , vol.858 , Issue.1 , pp. 55-60
    • Shimakura, A.1    Kamanaka, Y.2    Ikeda, Y.3    Kondo, K.4    Suzuki, Y.5    Umemura, K.6
  • 35
    • 70449369248 scopus 로고    scopus 로고
    • The roles of tumor necrosis factor-alpha in colon tight junction protein expression and intestinal mucosa structure in a mouse model of acute liver failure
    • 19772664 10.1186/1471-230X-9-70
    • Song HL, Lv S, Liu P (2009) The roles of tumor necrosis factor-alpha in colon tight junction protein expression and intestinal mucosa structure in a mouse model of acute liver failure. BMC Gastroenterol 9:70
    • (2009) BMC Gastroenterol , vol.9 , pp. 70
    • Song, H.L.1    Lv, S.2    Liu, P.3
  • 36
    • 0027196253 scopus 로고
    • Changes in amino acid neurotransmitters and cerebral blood flow in the ischemic penumbral region following middle cerebral artery occlusion in the rat: Correlation with histopathology
    • Takagi K, Ginsberg MD, Globus MY, Dietrich WD, Martinez E, Kraydieh S, Busto R (1993) Changes in amino acid neurotransmitters and cerebral blood flow in the ischemia penumbral region following middle cerebral artery occlusion in the rat: correlation with histopathology. J Cereb Blood Flow Metab 13(4):575-585 (Pubitemid 23187500)
    • (1993) Journal of Cerebral Blood Flow and Metabolism , vol.13 , Issue.4 , pp. 575-585
    • Takagi, K.1    Ginsberg, M.D.2    Globus, M.Y.-T.3    Dietrich, W.D.4    Martinez, E.5    Kraydieh, S.6    Busto, R.7
  • 37
    • 0036627211 scopus 로고    scopus 로고
    • Tight junctions of the blood-brain barrier: Development, composition and regulation
    • DOI 10.1016/S1537-1891(02)00200-8, PII S1537189102002008
    • Wolburg H, Lippoldt A (2002) Tight junctions of the blood-brain barrier: development, composition and regulation. Vascul Pharmacol 38(6):323-337 (Pubitemid 36398254)
    • (2002) Vascular Pharmacology , vol.38 , Issue.6 , pp. 323-337
    • Wolburg, H.1    Lippoldt, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.