Neural lineage-specific homeoprotein BRN2 is directly involved in TTF1 expression in small-cell lung cancer

Laboratory Investigation

Volumn 93, Issue 4, 2013, Pages 408-421

  Sakaeda, Masashi ^a,b   Sato, Hanako ^c   Ishii, Jun ^a,b   Miyata, Chie ^c   Kamma, Hiroshi ^b   Shishido Hara, Yukiko ^b   Shimoyamada, Hiroaki ^b   Fujiwara, Masachika ^b   Endo, Tetsuya ^a,d   Tanaka, Ryota ^b   Kondo, Haruhiko ^b   Goya, Tomoyuki ^b   Aoki, Ichiro ^a   Yazawa, Takuya ^b  

^a YOKOHAMA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

BRN2; homeoprotein; small cell lung cancer; TTF1

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 3ALPHA; HEPATOCYTE NUCLEAR FACTOR 3BETA; HOMEODOMAIN PROTEIN; HOMEODOMAIN PROTEIN BRN2; RETROVIRUS VECTOR; SMALL INTERFERING RNA; THYROID TRANSCRIPTION FACTOR 1; TRANSCRIPTION FACTOR GATA 6; TRANSCRIPTION FACTOR PAX4; TRICHOSTATIN A; UNCLASSIFIED DRUG;

ADENOCARCINOMA; ARTICLE; BINDING SITE; CARCINOID; CELL LINEAGE; CHROMATIN IMMUNOPRECIPITATION; DEACETYLATION; EPIGENETICS; GENE ACTIVATION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LUNG SMALL CELL CANCER; METHYLATION; NERVE CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMALL CELL CARCINOMA; SQUAMOUS CELL CARCINOMA; TERMINAL SEQUENCE; TRANSCRIPTION INITIATION SITE; TRANSIENT TRANSFECTION;

CELL LINE, TUMOR; CELL LINEAGE; DNA-BINDING PROTEINS; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; HUMANS; LUNG NEOPLASMS; POU DOMAIN FACTORS; PROMOTER REGIONS, GENETIC; SMALL CELL LUNG CARCINOMA; TRANSCRIPTIONAL ACTIVATION;

EID: 84875753911     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2013.2     Document Type: Article

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