GPR34 as a lysophosphatidylserine receptor

Journal of Biochemistry

Volumn 153, Issue 4, 2013, Pages 327-329

  Makide, Kumiko ^a,b   Aoki, Junken ^a,b  

^a TOHOKU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

GPR34; lysophosphatidylserine

Indexed keywords

FATTY ACID; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 34; LYSOPHOSPHATIDYLSERINE; UNCLASSIFIED DRUG;

PROTEIN ANALYSIS; PROTEIN INDUCTION; PROTEIN STRUCTURE; REVIEW;

ANIMALS; FATTY ACIDS; HUMANS; LYSOPHOSPHOLIPIDS; RECEPTORS, LYSOPHOSPHOLIPID;

EID: 84875749991     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvt010     Document Type: Review

References (23)

1. Marchese, A., Sawzdargo, M., Nguyen, T., Cheng, R., Heng, H.H., Nowak, T., Im, D.S., Lynch, K.R., George, S.R., and O'Dowd, B.F. (1999) Discovery of three novel orphan G-protein-coupled receptors. Genomics 56, 12-21
2. Schoneberg, T., Schulz, A., Grosse, R., Schade, R., Henklein, P., Schultz, G., and Gudermann, T. (1999) A novel subgroup of class I G-protein-coupled receptors. Biochim. Biophys. Acta 1446, 57-70
3. Yanagida, K. and Ishii, S. (2011) Non-Edg family LPA receptors: the cutting edge of LPA research. J. Biochem. 150, 223-232
4. Makide, K., Kitamura, H., Sato, Y., Okutani, M., and Aoki, J. (2009) Emerging lysophospholipid mediators, lysophosphatidylserine, lysophosphatidylthreonine, lysophosphatidylethanolamine and lysophosphatidylglycerol. Prostaglandins Other Lipid Mediat. 89, 135-139
5. Frasch, S.C. and Bratton, D.L. (2012) Emerging roles for lysophosphatidylserine in resolution of inflammation. Prog. Lipid Res. 51, 199-207
6. Martin, T.W. and Lagunoff, D. (1979) Interactions of lysophospholipids and mast cells. Nature 279, 250-252
7. Smith, G.A., Hesketh, T.R., Plumb, R.W., and Metcalfe, J.C. (1979) The exogenous lipid requirement for histamine release from rat peritoneal mast cells stimulated by concanavalin A. FEBS Lett. 105, 58-62
8. Lourenssen, S. and Blennerhassett, M.G. (1998) Lysophosphatidylserine potentiates nerve growth factor-induced differentiation of PC12 cells. Neurosci. Lett. 248, 77-80
9. Park, K.S., Lee, H.Y., Kim, M.K., Shin, E.H., Jo, S.H., Kim, S.D., Im, D.S., and Bae, Y.S. (2006) Lysophosphatidylserine stimulates L2071 mouse fibroblast chemotactic migration via a process involving pertussis toxin-sensitive trimeric G-proteins. Mol. Pharmacol. 69, 1066-1073
10. Lee, S.Y., Lee, H.Y., Kim, S.D., Jo, S.H., Shim, J.W., Lee, H.J., Yun, J., and Bae, Y.S. (2008) Lysophosphatidylserine stimulates chemotactic migration in U87 human glioma cells. Biochem. Biophys. Res. Commun. 374, 147-151
11. Frasch, S.C., Fernandez-Boyanapalli, R.F., Berry, K.Z., Leslie, C.C., Bonventre, J.V., Murphy, R.C., Henson, P.M., and Bratton, D.L. (2011) Signaling via macrophage G2A enhances efferocytosis of dying neutrophils by augmentation of Rac activity. J. Biol. Chem. 286, 12108-12122
12. Sugo, T., Tachimoto, H., Chikatsu, T., Murakami, Y., Kikukawa, Y., Sato, S., Kikuchi, K., Nagi, T., Harada, M., Ogi, K., Ebisawa, M., and Mori, M. (2006) Identification of a lysophosphatidylserine receptor on mast cells. Biochem. Biophys. Res. Commun. 341, 1078-1087
13. Iwashita, M., Makide, K., Nonomura, T., Misumi, Y., Otani, Y., Ishida, M., Taguchi, R., Tsujimoto, M., Aoki, J., Arai, H., and Ohwada, T. (2009) Synthesis and evaluation of lysophosphatidylserine analogues as inducers of mast cell degranulation. Potent activities of lysophosphatidylthreonine and its 2-deoxy derivative. J. Med. Chem. 52, 5837-5863
14. Liebscher, I., Muller, U., Teupser, D., Engemaier, E., Engel, K.M., Ritscher, L., Thor, D., Sangkuhl, K., Ricken, A., Wurm, A., Piehler, D., Schmutzler, S., Fuhrmann, H., Albert, F. W., Reichenbach, A., Thiery, J., Schoneberg, T., and Schulz, A. (2011) Altered immune response in mice deficient for the G protein-coupled receptor GPR34. J. Biol. Chem. 286, 2101-2110
15. Kitamura, H., Makide, K., Shuto, A., Ikubo, M., Inoue, A., Suzuki, K., Sato, Y., Nakamura, S., Otani, Y., Ohwada, T., and Aoki, J. (2012) GPR34 is a receptor for lysophosphatidylserine with a fatty acid at the sn-2 position. J. Biochem. 151, 511-518
16. Inoue, A., Ishiguro, J., Kitamura, H., Arima, N., Okutani, M., Shuto, A., Higashiyama, S., Ohwada, T., Arai, H., Makide, K., and Aoki, J. (2012) TGFalpha shedding assay: an accurate and versatile method for detecting GPCR activation. Nat. Methods 9, 1021-1029
17. Sato, T., Aoki, J., Nagai, Y., Dohmae, N., Takio, K., Doi, T., Arai, H., and Inoue, K. (1997) Serine phospholipid-specific phospholipase A that is secreted from activated platelets. A new member of the lipase family. J. Biol. Chem. 272, 2192-2198
18. Kazantseva, A., Goltsov, A., Zinchenko, R., Grigorenko, A.P., Abrukova, A.V., Moliaka, Y.K., Kirillov, A.G., Guo, Z., Lyle, S., Ginter, E.K., and Rogaev, E.I. (2006) Human hair growth deficiency is linked to a genetic defect in the phospholipase gene LIPH. Science 314, 982-985
19. Shimomura, Y., Wajid, M., Petukhova, L., Shapiro, L., and Christiano, A.M. (2009) Mutations in the lipase H gene underlie autosomal recessive woolly hair/hypotrichosis. J. Invest. Dermatol. 129, 622-628
20. Pasternack, S.M., von Kugelgen, I., Aboud, K.A., Lee, Y.A., Ruschendorf, F., Voss, K., Hillmer, A.M., Molderings, G.J., Franz, T., Ramirez, A., Nurnberg, P., Nothen, M.M., and Betz, R.C. (2008) G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth. Nat. Genet. 40, 329-334
21. Shimomura, Y., Wajid, M., Ishii, Y., Shapiro, L., Petukhova, L., Gordon, D., and Christiano, A.M. (2008) Disruption of P2RY5, an orphan G proteincoupled receptor, underlies autosomal recessive woolly hair. Nat. Genet. 40, 335-339
22. Aoki, J., Inoue, A., Makide, K., Saiki, N., and Arai, H. (2007) Structure and function of extracellular phospholipase A1 belonging to the pancreatic lipase gene family. Biochimie 89, 197-204
23. Rao, S., Garrett-Sinha, L.A., Yoon, J., and Simon, M.C. (1999) The Ets factors PU.1 and Spi-B regulate the transcription in vivo of P2Y10, a lymphoid restricted heptahelical receptor. J. Biol. Chem. 274, 34245-34252