Pro- and antiarrhythmic effects of ATP-sensitive potassium current activation on reentry during early afterdepolarization-mediated arrhythmias

Heart Rhythm

Volumn 10, Issue 4, 2013, Pages 575-582

  Chang, Marvin G ^a   De Lange, Enno ^a   Calmettes, Guillaume ^a   Garfinkel, Alan ^a   Qu, Zhilin ^a   Weiss, James N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

ATP sensitive K channels; Bi excitability; Early afterdepolarizations; Pinacidil; Reentry; Torsades de pointes

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; NITRENDIPINE; PINACIDIL;

ANIMAL CELL; ARTICLE; COMPUTER SIMULATION; HEART ARRHYTHMIA; HEART DEPOLARIZATION; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HEART REPOLARIZATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIAS, CARDIAC; BODY SURFACE POTENTIAL MAPPING; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; HEART CONDUCTION SYSTEM; KATP CHANNELS; MYOCYTES, CARDIAC; PINACIDIL; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY; TORSADES DE POINTES;

EID: 84875696273     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2012.12.017     Document Type: Article

References (30)

1. M.G. Chang, D. Sato, and E. de Lange Bi-stable wave propagation and early afterdepolarization-mediated cardiac arrhythmias Heart Rhythm 9 2012 115 122
2. F.A. Fish, C. Prakash, and D.M. Roden Suppression of repolarization- related arrhythmias in vitro and in vivo by low-dose potassium channel activators Circ Res 82 1990 1362 1369
3. W. Spinelli, S. Sorota, and M. Siegal Antiarrhythmic actions of the ATP-regulated K current activated by pinacidil Circ Res 68 1991 1127 1137
4. L. Carlsson, C. Abrahamsson, and L. Drews Antiarrhythmic effects of potassium channel openers in rhythm abnormalities related to delayed repolarization Circulation 85 1992 1491 1500
5. T. Sato, Y. Hata, M. Yamamoto, and H. Morita Early afterdepolarization abolished by potassium channel opener in a patient with idiopathic long QT syndrome J Cardiovasc Electrophysiol 6 1995 279 282
6. ATP channel opener, rilmakalim, in rabbit cardiac cells Gen Pharmacol 29 1997 201 205
7. O. Watanabe, T. Okumura, and H. Takeda Nicorandil, a potassium channel opener, abolished torsades de pointes in a patient with complete atrioventricular block Pacing Clin Electrophysiol 22 1999 686 688
8. W. Shimizu, and C. Antzelevitch Effects of a K channel opener to reduce transmural dispersion of repolarization and prevent torsade de pointes in LQT1, LQT2, and LQT3 models of the long-QT syndrome Circulation 102 2000 706 712
9. M. Chinushi, H. Kasai, and M. Tagawa Triggers of ventricular tachyarrhythmias and therapeutic effects of nicorandil in canine models of LQT2 and LQT3 syndromes J Am Coll Cardiol 40 2002 555 562
10. D.M. Krikler, and P.V. Curry Torsade de pointes, an atypical ventricular tachycardia Br Heart J 38 1976 117 120
11. N. El-Sherif, and G. Turitto Torsade de pointes Curr Opin Cardiol 18 2003 6 13
12. B.J. Drew, M.J. Ackerman, and M. Funk Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart association and the American College of Cardiology Foundation Circulation 121 2010 1047 1060
13. M.R. Abraham, C.A. Henrikson, and L. Tung Antiarrhythmic engineering of skeletal myoblasts for cardiac transplantation Circ Res 97 2005 159 167
14. C. de Diego, R.K. Pai, and A.S. Dave Spatially discordant alternans in cardiomyocyte monolayers Am J Physiol Heart Circ Physiol 294 2008 H1417 H1425
15. G. Calmettes, G.B. Drummond, and S.L. Vowler Making do with what we have: use your bootstraps J Physiol 590 2012 3403 3406
16. A. Mahajan, Y. Shiferaw, and D. Sato A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates Biophys J 94 2008 392 410
17. J.M. Ferrero Jr, J. Saiz, and J.M. Ferrero Simulation of action potentials from metabolically impaired cardiac myocytes: role of ATP-sensitive K current Circ Res 79 1996 208 221
18. M.G. Chang, C.Y. Chang, and E. de Lange Dynamics of early afterdepolarization- mediated triggered activity in cardiac monolayers Biophys J 102 2012 2706 2714
19. M.G. Chang, Y. Zhang, and C.Y. Chang Spiral waves and reentry dynamics in an in vitro model of the healed infarct border zone Circ Res 105 2009 1062 1071
20. Y. Asano, J.M. Davidenko, and W.T. Baxter Optical mapping of drug-induced polymorphic arrhythmias and torsade de pointes in the isolated rabbit heart J Am Coll Cardiol 29 1997 831 842
21. B.R. Choi, F. Burton, and G. Salama Cytosolic Ca triggers early afterdepolarizations and torsade de pointes in rabbit hearts with type 2 long QT syndrome J Physiol 543 2002 615 631
22. S. Nattel, J. Kneller, and R. Zou Mechanisms of termination of atrial fibrillation by class I antiarrhythmic drugs: Evidence from clinical, experimental, and mathematical modeling studies J Cardiovasc Electrophysiol 14 2003 S133 S139
23. Z. Qu, and J.N. Weiss Effects of Na and K channel blockade on vulnerability to and termination of fibrillation in simulated normal cardiac tissue Am J Physiol Heart Circ Physiol 289 2005 H1692 H1701
24. Z. Qu Critical mass hypothesis revisited: Role of dynamical wave stability in spontaneous termination of cardiac fibrillation Am J Physiol 290 2006 H255 H263
25. M. Yamazaki, H. Honjo, and H. Nakagawa Mechanisms of destabilization and early termination of spiral wave reentry in the ventricle by a class III antiarrhythmic agent, nifekalant Am J Physiol Heart Circ Physiol 292 2007 H539 H548
26. R.B. Sekar, E. Kizana, and H.C. Cho IK1 heterogeneity affects genesis and stability of spiral waves in cardiac myocyte monolayers Circ Res 104 2009 355 364
27. D.M. Pedrotty, R.Y. Klinger, and R.D. Kirkton Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes Cardiovasc Res 83 2009 688 697
28. C.E. Kossmann The long QT interval and syndromes Adv Intern Med 32 1987 87 110
29. J.T. Vermeulen Mechanisms of arrhythmias in heart failure J Cardiovasc Electrophysiol 9 1998 208 221
30. I. Splawski, K.W. Timothy, and N. Decher Inaugural article: Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations Proc Natl Acad Sci 102 2005 8089 8096