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Volumn 98, Issue 4, 2013, Pages 626-634

Association between B-cell receptor responsiveness and disease progression in B-cell chronic lymphocytic leukemia: Results from single cell network profiling studies

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD38 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN M ANTIBODY; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE SYK; PROTEIN KINASE ZAP 70; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; SYNAPTOTAGMIN I;

EID: 84875678492     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2012.071910     Document Type: Article
Times cited : (31)

References (34)
  • 1
    • 34249733155 scopus 로고    scopus 로고
    • Prognostic nomogram and index for overall survival in previously untreated patients with chronic lymphocytic leukemia
    • Wierda WG, O'Brien S, Wang X, Faderl S, Ferrajoli A, Do KA, et al. Prognostic nomogram and index for overall survival in previously untreated patients with chronic lymphocytic leukemia. Blood. 2007;109(11): 4679-85.
    • (2007) Blood. , vol.109 , Issue.11 , pp. 4679-4685
    • Wierda, W.G.1    O'Brien, S.2    Wang, X.3    Faderl, S.4    Ferrajoli, A.5    Do, K.A.6
  • 2
    • 59449108884 scopus 로고    scopus 로고
    • Validation of a new prognostic index for patients with chronic lymphocytic leukemia
    • Shanafelt TD, Jenkins G, Call TG, Zent CS, Slager S, Bowen DA, et al. Validation of a new prognostic index for patients with chronic lymphocytic leukemia. Cancer. 2009;115(2):363-72.
    • (2009) Cancer. , vol.115 , Issue.2 , pp. 363-372
    • Shanafelt, T.D.1    Jenkins, G.2    Call, T.G.3    Zent, C.S.4    Slager, S.5    Bowen, D.A.6
  • 3
    • 80755127112 scopus 로고    scopus 로고
    • Multivariable model for time to first treatment in patients with chronic lymphocytic leukemia
    • Wierda WG, O'Brien S, Wang X, Faderl S, Ferrajoli A, Do KA, et al. Multivariable model for time to first treatment in patients with chronic lymphocytic leukemia. J Clin Oncol. 2011;29(31):4088-95.
    • (2011) J Clin Oncol. , vol.29 , Issue.31 , pp. 4088-4095
    • Wierda, W.G.1    O'Brien, S.2    Wang, X.3    Faderl, S.4    Ferrajoli, A.5    Do, K.A.6
  • 4
    • 85027920745 scopus 로고    scopus 로고
    • Prognostic factors in chronic lymphocytic leukemia-what do we need to know?
    • Cramer P, Hallek M. Prognostic factors in chronic lymphocytic leukemia-what do we need to know? Nat Rev Clin Oncol. 2011;8(1):38-47.
    • (2011) Nat Rev Clin Oncol. , vol.8 , Issue.1 , pp. 38-47
    • Cramer, P.1    Hallek, M.2
  • 5
    • 77949447063 scopus 로고    scopus 로고
    • Predicting clinical outcome in CLL: How and why
    • Shanafelt TD. Predicting clinical outcome in CLL: how and why. Hematology Am Soc Hematol Educ Program. 2009;2009(1): 421-9.
    • (2009) Hematology Am Soc Hematol Educ Program. , vol.2009 , Issue.1 , pp. 421-429
    • Shanafelt, T.D.1
  • 7
    • 84863807029 scopus 로고    scopus 로고
    • Signaling pathways activated by the B-cell receptor in chronic lymphocytic leukemia
    • Scupoli MT, Pizzolo G. Signaling pathways activated by the B-cell receptor in chronic lymphocytic leukemia. Expert Rev Hematol. 2012;5(3):341-8.
    • (2012) Expert Rev Hematol. , vol.5 , Issue.3 , pp. 341-348
    • Scupoli, M.T.1    Pizzolo, G.2
  • 8
  • 9
    • 84864075343 scopus 로고    scopus 로고
    • The degree of BCR and NFAT activation predicts clinical outcomes in chronic lymphocytic leukemia
    • Le Roy C, Deglesne PA, Chevallier N, Beitar T, Eclache V, Quettier M, et al. The degree of BCR and NFAT activation predicts clinical outcomes in chronic lymphocytic leukemia. Blood. 2012;120(2):356-65.
    • (2012) Blood. , vol.120 , Issue.2 , pp. 356-365
    • Le Roy, C.1    Deglesne, P.A.2    Chevallier, N.3    Beitar, T.4    Eclache, V.5    Quettier, M.6
  • 10
    • 84857497433 scopus 로고    scopus 로고
    • Mechanisms and clinical significance of BIM phosphorylation in chronic lymphocytic leukemia
    • Paterson A, Mockridge CI, Adams JE, Krysov S, Potter KN, Duncombe AS, et al. Mechanisms and clinical significance of BIM phosphorylation in chronic lymphocytic leukemia. Blood. 2012;119(7):1726-36.
    • (2012) Blood. , vol.119 , Issue.7 , pp. 1726-1736
    • Paterson, A.1    Mockridge, C.I.2    Adams, J.E.3    Krysov, S.4    Potter, K.N.5    Duncombe, A.S.6
  • 11
    • 84866547889 scopus 로고    scopus 로고
    • T-cell independent, B-cell receptor-mediated induction of telomerase activity differs among IGHV mutation-based subgroups of chronic lymphocytic leukemia patients
    • Damle RN, Temburni S, Banapour T, Paul S, Mongini PK, Allen SL, et al. T-cell independent, B-cell receptor-mediated induction of telomerase activity differs among IGHV mutation-based subgroups of chronic lymphocytic leukemia patients. Blood. 2012;120(12):2438-49.
    • (2012) Blood. , vol.120 , Issue.12 , pp. 2438-2449
    • Damle, R.N.1    Temburni, S.2    Banapour, T.3    Paul, S.4    Mongini, P.K.5    Allen, S.L.6
  • 12
    • 64849113027 scopus 로고    scopus 로고
    • Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells
    • Gobessi S, Laurenti L, Longo PG, Carsetti L, Berno V, Sica S, et al. Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells. Leukemia. 2009;23(4):686-97.
    • (2009) Leukemia. , vol.23 , Issue.4 , pp. 686-697
    • Gobessi, S.1    Laurenti, L.2    Longo, P.G.3    Carsetti, L.4    Berno, V.5    Sica, S.6
  • 13
    • 84859256604 scopus 로고    scopus 로고
    • Inhibiting B-cell receptor signaling pathways in chronic lymphocytic leukemia
    • Burger JA. Inhibiting B-cell receptor signaling pathways in chronic lymphocytic leukemia. Curr Hematol Malig Rep. 2012;7 (1):26-33.
    • (2012) Curr Hematol Malig Rep. , vol.7 , Issue.1 , pp. 26-33
    • Burger, J.A.1
  • 14
    • 3242683662 scopus 로고    scopus 로고
    • Single cell profiling of potentiated phospho-protein networks in cancer cells
    • Irish JM, Hovland R, Krutzik PO, Perez OD, Bruserud Ø, Gjertsen BT, et al. Single cell profiling of potentiated phospho-protein networks in cancer cells. Cell. 2004;118(2):217-28.
    • (2004) Cell. , vol.118 , Issue.2 , pp. 217-228
    • Irish, J.M.1    Hovland, R.2    Krutzik, P.O.3    Perez, O.D.4    Bruserud, O.5    Gjertsen, B.T.6
  • 15
    • 33644833555 scopus 로고    scopus 로고
    • Mapping normal and cancer cell signalling networks: Towards single-cell proteomics
    • Irish JM, Kotecha N, Nolan GP. Mapping normal and cancer cell signalling networks: towards single-cell proteomics. Nat Rev Cancer. 2006;6(2):146-55.
    • (2006) Nat Rev Cancer. , vol.6 , Issue.2 , pp. 146-155
    • Irish, J.M.1    Kotecha, N.2    Nolan, G.P.3
  • 16
    • 78649515407 scopus 로고    scopus 로고
    • Modulated multiparametric phosphoflow cytometry in hematological malignancies: Technology and clinical applications
    • Covey TM, Cesano A. Modulated multiparametric phosphoflow cytometry in hematological malignancies: technology and clinical applications. Best Pract Res Clin Haematol. 2010;23(3):319-31.
    • (2010) Best Pract Res Clin Haematol. , vol.23 , Issue.3 , pp. 319-331
    • Covey, T.M.1    Cesano, A.2
  • 17
    • 77954710869 scopus 로고    scopus 로고
    • Dynamic singlecell network profiles in acute myelogenous leukemia are associated with patient response to standard induction therapy
    • Kornblau SM, Minden MD, Rosen DB, Putta S, Cohen A, Covey T, et al. Dynamic singlecell network profiles in acute myelogenous leukemia are associated with patient response to standard induction therapy. Clin Cancer Res. 2010;16(14): 3721-33.
    • (2010) Clin Cancer Res. , vol.16 , Issue.14 , pp. 3721-3733
    • Kornblau, S.M.1    Minden, M.D.2    Rosen, D.B.3    Putta, S.4    Cohen, A.5    Covey, T.6
  • 18
    • 78149431428 scopus 로고    scopus 로고
    • Functional characterization of FLT3 receptor signaling deregulation in acute myeloid leukemia by single cell network profiling (SCNP)
    • Rosen DB, Minden MD, Kornblau SM, Cohen A, Gayko U, Putta S, et al. Functional characterization of FLT3 receptor signaling deregulation in acute myeloid leukemia by single cell network profiling (SCNP). PLoS One. 2010;5(10):e13543.
    • (2010) PLoS One. , vol.5 , Issue.10
    • Rosen, D.B.1    Minden, M.D.2    Kornblau, S.M.3    Cohen, A.4    Gayko, U.5    Putta, S.6
  • 19
    • 84856917555 scopus 로고    scopus 로고
    • Single-cell network profiling of peripheral blood mononuclear cells from healthy donors reveals age-and race-associated differences in immune signaling pathway activation
    • Longo DM, Louie B, Putta S, Evensen E, Ptacek J, Cordeiro J, et al. Single-cell network profiling of peripheral blood mononuclear cells from healthy donors reveals age-and race-associated differences in immune signaling pathway activation. J Immunol. 2012;188(4):1717-25.
    • (2012) J Immunol. , vol.188 , Issue.4 , pp. 1717-1725
    • Longo, D.M.1    Louie, B.2    Putta, S.3    Evensen, E.4    Ptacek, J.5    Cordeiro, J.6
  • 20
    • 77957978115 scopus 로고    scopus 로고
    • Single-cell network profiling (SCNP) by flow cytometry in autoimmune disease
    • Covey TM, Cesano A, Parkinson DR. Single-cell network profiling (SCNP) by flow cytometry in autoimmune disease. Autoimmunity. 2010;43(7):550-9.
    • (2010) Autoimmunity. , vol.43 , Issue.7 , pp. 550-559
    • Covey, T.M.1    Cesano, A.2    Parkinson, D.R.3
  • 21
    • 0029981025 scopus 로고    scopus 로고
    • National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment
    • Cheson BD, Bennett JM, Grever M, Kay N, Keating MJ, O'Brien S, et al. National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood. 1996;87(12):4990-7.
    • (1996) Blood. , vol.87 , Issue.12 , pp. 4990-4997
    • Cheson, B.D.1    Bennett, J.M.2    Grever, M.3    Kay, N.4    Keating, M.J.5    O'Brien, S.6
  • 22
    • 45149100665 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
    • Hallek M, Cheson BD, Catovsky D, Caligaris-Cappio F, Dighiero G, Döhner H, et al. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood. 2008;111 (12):5446-56.
    • (2008) Blood. , vol.111 , Issue.12 , pp. 5446-5456
    • Hallek, M.1    Cheson, B.D.2    Catovsky, D.3    Caligaris-Cappio, F.4    Dighiero, G.5    Döhner, H.6
  • 23
    • 33845538314 scopus 로고    scopus 로고
    • ZAP-70 expression, as detected by immunohistochemistry on bone marrow biopsies from earlyphase CLL patients, is a strong adverse prognostic factor
    • Zanotti R, Ambrosetti A, Lestani M, Ghia P, Pattaro C, Remo A, et al. ZAP-70 expression, as detected by immunohistochemistry on bone marrow biopsies from earlyphase CLL patients, is a strong adverse prognostic factor. Leukemia. 2007;21(1): 102-9.
    • (2007) Leukemia. , vol.21 , Issue.1 , pp. 102-109
    • Zanotti, R.1    Ambrosetti, A.2    Lestani, M.3    Ghia, P.4    Pattaro, C.5    Remo, A.6
  • 24
    • 84863393783 scopus 로고    scopus 로고
    • Functional pathway analysis in acute myeloid leukemia using single cell network profiling (SCNP) assay: Effect of specimen source (bone marrow or peripheral blood) on assay readouts
    • Cesano A, Rosen DB, O'Meara P, Putta S, Gayko U, Spellmeyer DC, et al. Functional pathway analysis in acute myeloid leukemia using single cell network profiling (SCNP) assay: effect of specimen source (bone marrow or peripheral blood) on assay readouts. Cytometry B Clin Cytom. 2012;82(3):158-72.
    • (2012) Cytometry B Clin Cytom. , vol.82 , Issue.3 , pp. 158-172
    • Cesano, A.1    Rosen, D.B.2    O'Meara, P.3    Putta, S.4    Gayko, U.5    Spellmeyer, D.C.6
  • 25
    • 0030069896 scopus 로고    scopus 로고
    • Multivariable prognostic models: Issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors
    • Harrell FE Jr, Lee KL, Mark DB. Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med. 1996;15(4):361-87.
    • (1996) Stat Med. , vol.15 , Issue.4 , pp. 361-387
    • Harrell Jr., F.E.1    Lee, K.L.2    Mark, D.B.3
  • 27
    • 84863393559 scopus 로고    scopus 로고
    • Surface IgM stimulation induces MEK1/2-dependent MYC expression in chronic lymphocytic leukemia cells
    • Krysov S, Dias S, Paterson A, Mockridge CI, Potter KN, Smith KA, et al. Surface IgM stimulation induces MEK1/2-dependent MYC expression in chronic lymphocytic leukemia cells. Blood. 2012;119(1):170-9.
    • (2012) Blood. , vol.119 , Issue.1 , pp. 170-179
    • Krysov, S.1    Dias, S.2    Paterson, A.3    Mockridge, C.I.4    Potter, K.N.5    Smith, K.A.6
  • 28
    • 33845526567 scopus 로고    scopus 로고
    • The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease
    • Longo PG, Laurenti L, Gobessi S, Petlickovski A, Pelosi M, Chiusolo P, et al. The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease. Leukemia. 2007;21(1):110-20.
    • (2007) Leukemia. , vol.21 , Issue.1 , pp. 110-120
    • Longo, P.G.1    Laurenti, L.2    Gobessi, S.3    Petlickovski, A.4    Pelosi, M.5    Chiusolo, P.6
  • 29
    • 0036584284 scopus 로고    scopus 로고
    • Regulation of B-cell signal transduction by adaptor proteins
    • Kurosaki T. Regulation of B-cell signal transduction by adaptor proteins. Nat Rev Immunol. 2002;2(5):354-63.
    • (2002) Nat Rev Immunol. , vol.2 , Issue.5 , pp. 354-363
    • Kurosaki, T.1
  • 30
    • 18244413206 scopus 로고    scopus 로고
    • Ras mediates effector pathways responsible for pre-B cell survival, which is essential for the developmental progression to the late pre-B cell stage
    • Nagaoka H, Takahashi Y, Hayashi R, Nakamura T, Ishii K, Matsuda J, et al. Ras mediates effector pathways responsible for pre-B cell survival, which is essential for the developmental progression to the late pre-B cell stage. J Exp Med. 2000;192(2):171-82.
    • (2000) J Exp Med. , vol.192 , Issue.2 , pp. 171-182
    • Nagaoka, H.1    Takahashi, Y.2    Hayashi, R.3    Nakamura, T.4    Ishii, K.5    Matsuda, J.6
  • 32
    • 47249152803 scopus 로고    scopus 로고
    • Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: A molecular signature of anergy
    • Muzio M, Apollonio B, Scielzo C, Frenquelli M, Vandoni I, Boussiotis V, et al. Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergy. Blood. 2008;112(1):188-95.
    • (2008) Blood. , vol.112 , Issue.1 , pp. 188-195
    • Muzio, M.1    Apollonio, B.2    Scielzo, C.3    Frenquelli, M.4    Vandoni, I.5    Boussiotis, V.6
  • 33
    • 84866152172 scopus 로고    scopus 로고
    • Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling
    • Dühren-von Minden M, Ubelhart R, Schneider D, Wossning T, Bach MP, Buchner M, et al. Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling. Nature. 2012;489(7415):309-12.
    • (2012) Nature. , vol.489 , Issue.7415 , pp. 309-312
    • Dühren-von Minden, M.1    Ubelhart, R.2    Schneider, D.3    Wossning, T.4    Bach, M.P.5    Buchner, M.6
  • 34
    • 34248591612 scopus 로고    scopus 로고
    • Targeting the Raf-MEKERK mitogen-activated protein kinase cascade for the treatment of cancer
    • Roberts PJ, Der CJ. Targeting the Raf-MEKERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene. 2007;26(22): 3291-310.
    • (2007) Oncogene. , vol.26 , Issue.22 , pp. 3291-3310
    • Roberts, P.J.1    Der, C.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.