Identification of inhibitors of α2β1 integrin, members of C-lectin type proteins, in Echis sochureki venom

Toxicology and Applied Pharmacology

Volumn 269, Issue 1, 2013, Pages 34-42

  Jakubowski, Piotr ^a   Calvete, Juan J ^b   Eble, Johannes A ^c   Lazarovici, Philip ^d   Marcinkiewicz, Cezary ^a  

^a Temple University   (United States)

^b INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

^c UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^d HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

C lectin type proteins; Cell adhesion; Collagen receptors; Glioma cells; Integrins; Snake venom proteins

Indexed keywords

COLLAGEN TYPE 1; FIBRONECTIN; HETERODIMER; PROTEIN; SNAKE VENOM; SOCHICETIN A; SOCHICETIN B; SOCHICETIN C; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 2; VINCULIN;

ARTICLE; CANCER CELL CULTURE; CELL ADHESION; CONTROLLED STUDY; ECHIS SOCHUREKI; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL FILTRATION CHROMATOGRAPHY; GLIOMA CELL; HUMAN; HUMAN CELL; ION EXCHANGE CHROMATOGRAPHY; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN QUATERNARY STRUCTURE; PROTEIN STRUCTURE; REVERSED PHASE LIQUID CHROMATOGRAPHY; SNAKE; THROMBOCYTE AGGREGATION;

ANIMALS; CELL ADHESION; CELL SHAPE; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; CHROMATOGRAPHY, REVERSE-PHASE; COLLAGEN TYPE I; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBRONECTINS; GLIOMA; GLUTATHIONE TRANSFERASE; HUMANS; INTEGRIN ALPHA2BETA1; ISOENZYMES; K562 CELLS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; VIPER VENOMS;

ECHIS CARINATUS SOCHUREKI;

EID: 84875662036     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.03.002     Document Type: Article

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