Underexpression of tumour suppressor LKB1 in clear cell renal cell carcinoma is common and confers growth advantage in vitro and in vivo

British Journal of Cancer

Volumn 108, Issue 2, 2013, Pages 327-333

  Duivenvoorden, W C ^a   Beatty, L K ^a   Lhotak, S ^a   Hill, B ^a   Mak, I ^a   Paulin, G ^a   Gallino, D ^a   Popovic, S ^a   Austin, R C ^a   Pinthus, J H ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

AMPK; Kidney cancer; LKB1; Metabolism; Renal cell carcinoma

Indexed keywords

PROTEIN KINASE LKB1; VASCULOTROPIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA; STK11 PROTEIN, HUMAN; VASCULOTROPIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CARCINOMA; KIDNEY PARENCHYMA; MALE; METABOLIC REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAINING; TISSUE MICROARRAY; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CANCER INVASION; GENETICS; KIDNEY TUMOR; METABOLISM; NUDE MOUSE; PHOSPHORYLATION; RNA INTERFERENCE; SECRETION (PROCESS); SIGNAL TRANSDUCTION; TUMOR CELL LINE; XENOGRAFT;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; KIDNEY NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM INVASIVENESS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSPLANTATION, HETEROLOGOUS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MLCS; MLOWN;

EID: 84875652331     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2012.574     Document Type: Article

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