A comparative study of glycerin fatty acid ester and magnesium stearate on the dissolution of acetaminophen tablets using the analysis of available surface area

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 78, Issue 3, 2011, Pages 492-498

  Uchimoto, Takeaki ^a   Iwao, Yasunori ^a   Takahashi, Kana ^a   Tanaka, Shoko ^a   Agata, Yasuyoshi ^a   Iwamura, Takeru ^a   Miyagishima, Atsuo ^a   Itai, Shigeru ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Available surface area; Dissolution rate; Extensibility; Glycerin fatty acid esters; Magnesium stearate

Indexed keywords

FATTY ACID ESTER; GLYCEROL; LUBRICATING AGENT; MAGNESIUM STEARATE; PARACETAMOL; SOLVENT;

ARTICLE; COMPARATIVE STUDY; DRUG SOLUBILITY; SCANNING ELECTRON MICROSCOPY;

ACETAMINOPHEN; ADHESIVES; ANALGESICS, NON-NARCOTIC; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; ESTERS; EXCIPIENTS; FATTY ACIDS; GLYCEROL; LUBRICANTS; PHARMACOKINETICS; SOLUBILITY; STEARIC ACIDS; SURFACE-ACTIVE AGENTS; TABLETS;

EID: 79960578096     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.01.014     Document Type: Article

References (22)

1. W.A. Strickland Jr., E. Nelson, L.W. Busse, and T. Higuchi The physics of tablet compression. IX. Fundamental aspects of tablet lubrication J. Am. Pharm. Assoc. Am. Pharm. (Baltim) 45 1956 51 55
2. O.K. Udeala, J.O. Onyechi, and S.I. Agu Preliminary evaluation of dika fat, a new tablet lubricant J. Pharm. Pharmacol. 32 1980 6 9 (Pubitemid 10184744)
3. L.E. Flores, R.L. Arellano, and J.J.D. Esquivel Lubricant susceptibility of cellactose and Avicel PH-200: a quantitative relationship Drug Dev. Ind. Pharm. 26 2000 297 305 (Pubitemid 30164744)
4. G. Levy, and R.H. Gumtow Effect of certain tablet formulation factors on dissolution rate of the active ingredient III. Tablet lubricants J. Pharm. Sci. 52 1963 1139 1144
5. K.S. Murthy, and J.C. Samyn Effect of shear mixing on in vitro drug release of capsule formulations containing lubricants J. Pharm. Sci. 66 1977 1215 1219
6. S.J. Homg, and S.K. Kim Effect of formulation factors on dissolution rate of nitrofurantoin tablet Soul Taehakkyo Yakhak Nonmunjip 10 1985 25 38
7. A.W. Hölzer, and J. Sjögren Evaluation of sodium stearyl fumarate as a tablet lubricant Int. J. Pharm. 2 1979 145 153 (Pubitemid 9151005)
8. Z.T. Chowhan, and L.H. Chi Drug-excipient interactions resulting from powder mixing. IV: role of lubricants and their effect on in vitro dissolution J. Pharm. Sci. 75 1986 542 545 (Pubitemid 16098034)
9. A.M. Salpekar, and L.L. Augsburger Magnesium lauryl sulfate in tableting: effect on ejection force and compressibility J. Pharm. Sci. 63 1974 289 293
10. T. Uurlu, and M. Turkolu Hexagonal boron nitride as a tablet lubricant and a comparison with conventional lubricants Int. J. Pharm. 353 2008 45 51
11. H. Aoshima, A. Miyagishima, Y. Nozawa, Y. Sadzuka, and T. Sonobe Glycerin fatty acid esters as a new lubricant of tablets Int. J. Pharm. 293 2005 25 34 (Pubitemid 40381077)
12. T. Uchimoto, Y. Iwao, Y. Ikegami, T. Murata, A. Miyagishima, T. Sonobe, and S. Itai Lubrication properties of potential alternative lubricants, glycerin fatty acid esters, to magnesium stearate Int. J. Pharm. 386 2010 91 98
13. Z.T. Chowhan, and L.H. Chi Drug-excipient interactions resulting from powder mixing. III: solid state properties and their effect on drug dissolution J. Pharm. Sci. 75 1986 534 541 (Pubitemid 16098033)
14. D. Shibata, Y. Shimada, Y. Yonezawa, H. Sunada, N. Otomo, and K. Kasahara Application and evaluation of sucrose fatty acid esters as lubricants in the production of pharmaceuticals J. Pharm. Sci. Technol. Jpn. 62 2002 133 145
15. M.R. Billany, and J.H. Richards Batch variation of magnesium stearate and its effect on the dissolution rate of salicylic acid from solid dosage forms Drug Dev. Ind. Pharm. 8 1982 497 511 (Pubitemid 13226634)
16. V.M. Lethola, J.T. Heinamaki, P. Nikupaavo, and J.K. Yliruusi Effect of some excipients and compression pressure on the adhesion of aqueous-based hydroxypropyl methylcellulose film coatings to tablet surfaces Drug Dev. Ind. Pharm. 21 1995 1365 1375
17. S. Kouchiwa, M. Nemoto, S. Itai, H. Murayama, and T. Nagai Prediction of available surface area of powdered particles of flufenamic acid in tablets Chem. Pharm. Bull. 33 1985 1641 1651 (Pubitemid 15046094)
18. S. Itai, S. Kouchiwa, M. Nemoto, H. Murayama, and T. Nagai Effect of compression pressure and formulation on the available surface area of flufenamic acid in tablets Chem. Pharm. Bull. 34 1986 1264 1274 (Pubitemid 16103745)
19. J. Wang, H. Wen, and D. Desai Lubrication in tablet formulations Eur. J. Pharm. Biopharm. 75 2010 1 15
20. Y. Agata, Y. Iwao, A. Miyagishima, and S. Itai Novel mathematical model for predicting the dissolution profile of spherical particles under non-sink conditions Chem. Pharm. Bull. 58 2010 511 515
21. A.C. Shah, and A.R. Mlodozeniec Mechanism of surface lubrication: influence of duration of lubricant-excipient mixing on processing characteristics of powders and properties of compressed tablets J. Pharm. Sci. 66 1977 1377 1382
22. F. Ebba, P. Piccerelle, P. Prinderre, D. Opota, and J. Joachim Stress relaxation studies of granules as a function of different lubricants Eur. J. Pharm. Biopharm. 52 2001 211 220 (Pubitemid 32761681)