메뉴 건너뛰기




Volumn 80, Issue 5, 2013, Pages 578-581

Suggested involvement of ketone bodies in the pathogenesis of the metabolic syndrome

Author keywords

[No Author keywords available]

Indexed keywords

ACETOACETIC ACID; ALPHA TOCOPHEROL; BUTYRIC ACID; GLUTAMIC ACID; HYDROGEN PEROXIDE; KETONE BODY; LIPOPOLYSACCHARIDE; PYRUVIC ACID; SHORT CHAIN FATTY ACID;

EID: 84875601518     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2013.01.029     Document Type: Article
Times cited : (2)

References (44)
  • 1
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil G.S. Inflammation and metabolic disorders. Nature 2006, 444:860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 2
    • 33644633736 scopus 로고    scopus 로고
    • Biomarkers and potential mechanisms of obesity-induced oxidant stress in humans
    • Vincent H.K., Taylor A.G. Biomarkers and potential mechanisms of obesity-induced oxidant stress in humans. Int J Obes (Lond) 2006, 30:400-418.
    • (2006) Int J Obes (Lond) , vol.30 , pp. 400-418
    • Vincent, H.K.1    Taylor, A.G.2
  • 3
    • 0034137696 scopus 로고    scopus 로고
    • Suppression of feed intake after parenteral administration of d-(-)-hydroxybutirate in pygmy goats
    • Rossi R., Dorig S., Del prete E., Sharrer E. Suppression of feed intake after parenteral administration of d-(-)-hydroxybutirate in pygmy goats. J Vet Med 2000, 47:9-16.
    • (2000) J Vet Med , vol.47 , pp. 9-16
    • Rossi, R.1    Dorig, S.2    Del prete, E.3    Sharrer, E.4
  • 4
    • 0021999068 scopus 로고
    • Ketone kinetics and d-(-)-3-hydroxybutyrate-induced inhibition of feeding in rats
    • Langhans W., Pantel K., Scharrer E. Ketone kinetics and d-(-)-3-hydroxybutyrate-induced inhibition of feeding in rats. Physiol Behav 1985, 34:579-582.
    • (1985) Physiol Behav , vol.34 , pp. 579-582
    • Langhans, W.1    Pantel, K.2    Scharrer, E.3
  • 6
    • 77957777952 scopus 로고    scopus 로고
    • Mitochondrial HMGCoA synthase partially contributes to antioxidant protection in the kidney of stroke-prone spontaneously hypertensive rats
    • Yi W., Fu P., Fan Z., Aso H., Tian C., Meng Y., et al. Mitochondrial HMGCoA synthase partially contributes to antioxidant protection in the kidney of stroke-prone spontaneously hypertensive rats. Nutrition 2010, 26:1176-1180.
    • (2010) Nutrition , vol.26 , pp. 1176-1180
    • Yi, W.1    Fu, P.2    Fan, Z.3    Aso, H.4    Tian, C.5    Meng, Y.6
  • 8
    • 1042299789 scopus 로고    scopus 로고
    • The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, insulin resistance, and mitochondrial metabolism
    • Veech R. The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, insulin resistance, and mitochondrial metabolism. Prostaglandins Leukot Essent Fatty Acids 2004, 70:309-319.
    • (2004) Prostaglandins Leukot Essent Fatty Acids , vol.70 , pp. 309-319
    • Veech, R.1
  • 9
    • 0019940133 scopus 로고
    • Utilization of nutrients by isolated epithelial cells of the rat colon
    • Roediger W.E. Utilization of nutrients by isolated epithelial cells of the rat colon. Gastroenterology 1982, 83:424-429.
    • (1982) Gastroenterology , vol.83 , pp. 424-429
    • Roediger, W.E.1
  • 10
    • 69549114504 scopus 로고    scopus 로고
    • Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in caco-2 cell monolayers
    • Peng L., Li Z.-R., Green R.S., Holzman I.R., Lin J. Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in caco-2 cell monolayers. J Nutr 2009, 139:1619-1625.
    • (2009) J Nutr , vol.139 , pp. 1619-1625
    • Peng, L.1    Li, Z.-R.2    Green, R.S.3    Holzman, I.R.4    Lin, J.5
  • 11
    • 1642539992 scopus 로고    scopus 로고
    • Expression of mitochondrial HMGCoA synthase and glutaminase in the colonic mucosa is modulated by bacterial species
    • Cherbuy C., Andrieux C., Honvo-Houeto E., et al. Expression of mitochondrial HMGCoA synthase and glutaminase in the colonic mucosa is modulated by bacterial species. Eur J Biochem 2004, 271:87-95.
    • (2004) Eur J Biochem , vol.271 , pp. 87-95
    • Cherbuy, C.1    Andrieux, C.2    Honvo-Houeto, E.3
  • 12
    • 69449089135 scopus 로고    scopus 로고
    • Butyrate-induced transcriptional changes in human colonic mucosa
    • Vanhoutvin S.A.L.W., Troost F.J., Hamer H.M., et al. Butyrate-induced transcriptional changes in human colonic mucosa. PLoS One 2009, 4:e6759.
    • (2009) PLoS One , vol.4
    • Vanhoutvin, S.A.L.W.1    Troost, F.J.2    Hamer, H.M.3
  • 13
    • 59149103242 scopus 로고    scopus 로고
    • Butyrate modulates oxidative stress in the colonic mucosa of healthy humans
    • Hamer H.M., Jonkers D.M.A.E., Bast A., et al. Butyrate modulates oxidative stress in the colonic mucosa of healthy humans. Clin Nutr 2008, 28:88-93.
    • (2008) Clin Nutr , vol.28 , pp. 88-93
    • Hamer, H.M.1    Jonkers, D.M.A.E.2    Bast, A.3
  • 15
    • 0029907385 scopus 로고    scopus 로고
    • Withdrawal of butyrate from the colonic mucosa triggers " mass apoptosis" primarily in the G0/G1 phase of the cell cycle
    • Luciano L., Hass R., Busch W., von Engelhardt W., Reale E. Withdrawal of butyrate from the colonic mucosa triggers " mass apoptosis" primarily in the G0/G1 phase of the cell cycle. Cell Tissue Res 1996, 286:81-92.
    • (1996) Cell Tissue Res , vol.286 , pp. 81-92
    • Luciano, L.1    Hass, R.2    Busch, W.3    von Engelhardt, W.4    Reale, E.5
  • 16
    • 79960501919 scopus 로고    scopus 로고
    • Interaction between obesity and the gut microbiota: relevance in nutrition
    • Delzenne N., Cani P.D. Interaction between obesity and the gut microbiota: relevance in nutrition. Annu Rev Nutr 2011, 31:15-31.
    • (2011) Annu Rev Nutr , vol.31 , pp. 15-31
    • Delzenne, N.1    Cani, P.D.2
  • 17
    • 34848912627 scopus 로고    scopus 로고
    • Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxemia
    • Cani P.D., Neyrinck A.M., Fava F., et al. Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxemia. Diabetologia 2007, 50:2374-2383.
    • (2007) Diabetologia , vol.50 , pp. 2374-2383
    • Cani, P.D.1    Neyrinck, A.M.2    Fava, F.3
  • 18
    • 0030061922 scopus 로고    scopus 로고
    • IRS 1- mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha and obesity-induced insulin resistance
    • Hotamisligil G., Peraldi P., Budavari A., Ellis R., White M., Spigelman B. IRS 1- mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha and obesity-induced insulin resistance. Science 1996, 271:665-668.
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.5    Spigelman, B.6
  • 19
    • 34347399563 scopus 로고    scopus 로고
    • Metabolic endotoxemia initiates obesity and insulin resistance
    • Cani P.D., Amar J., Iglesias M.A., et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 2007, 56:1761-1772.
    • (2007) Diabetes , vol.56 , pp. 1761-1772
    • Cani, P.D.1    Amar, J.2    Iglesias, M.A.3
  • 20
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani P.D., Bibiloni R., Knauf C., et al. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 2008, 57:1470-1481.
    • (2008) Diabetes , vol.57 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3
  • 21
    • 33847040759 scopus 로고    scopus 로고
    • Increased intestinal permeability in obese mice: new evidence in the pathogenesis of non-alcoholic steatohepatitis
    • Brun P., Castagliuolo I., Di Leo V., et al. Increased intestinal permeability in obese mice: new evidence in the pathogenesis of non-alcoholic steatohepatitis. Am J Physiol Gastrointest Liver Physiol 2007, 292:g518-g525.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Brun, P.1    Castagliuolo, I.2    Di Leo, V.3
  • 22
    • 35848947008 scopus 로고    scopus 로고
    • Modulation of glucagons-like peptide 1 and energy metabolism by inulin and oligofructose: experimental data
    • Delzenne N.M., Cani P.D., Neyrinck A.M. Modulation of glucagons-like peptide 1 and energy metabolism by inulin and oligofructose: experimental data. J Nutr 2007, 137:2547s-2551s.
    • (2007) J Nutr , vol.137
    • Delzenne, N.M.1    Cani, P.D.2    Neyrinck, A.M.3
  • 23
    • 65249099918 scopus 로고    scopus 로고
    • Changes ion gut microbiota control inflammation in obese mice through a mechanism involving GLP-2 driven improvement of gut permeability
    • Cani P.D., Possemiers S., Van de Viele T., et al. Changes ion gut microbiota control inflammation in obese mice through a mechanism involving GLP-2 driven improvement of gut permeability. Gut 2009, 58:1091-1103.
    • (2009) Gut , vol.58 , pp. 1091-1103
    • Cani, P.D.1    Possemiers, S.2    Van de Viele, T.3
  • 24
    • 0037012406 scopus 로고    scopus 로고
    • Postprandial endothelial activation in healthy subjects and in type 2 diabetic patients. Role of fat and carbohydrate meals
    • Nappo F., Esposito K., Cioffi M., et al. Postprandial endothelial activation in healthy subjects and in type 2 diabetic patients. Role of fat and carbohydrate meals. J Am Coll Card 2002, 39:1145-1150.
    • (2002) J Am Coll Card , vol.39 , pp. 1145-1150
    • Nappo, F.1    Esposito, K.2    Cioffi, M.3
  • 25
    • 63449098729 scopus 로고    scopus 로고
    • Chylomicrons promote intestinal absorption of lipopolysaccharides
    • Goshal S., Witta J., Zhong J., de Villiers W., Eckardt E. Chylomicrons promote intestinal absorption of lipopolysaccharides. J Lipid Res 2009, 50:90-97.
    • (2009) J Lipid Res , vol.50 , pp. 90-97
    • Goshal, S.1    Witta, J.2    Zhong, J.3    de Villiers, W.4    Eckardt, E.5
  • 26
    • 0025356947 scopus 로고
    • Absorption, transport and distribution of vitamin E
    • Bjorneboe A., Bjorneboe Gunn-Elin A., Drevon C.A. Absorption, transport and distribution of vitamin E. J Nutr 1990, 120:233-242.
    • (1990) J Nutr , vol.120 , pp. 233-242
    • Bjorneboe, A.1    Bjorneboe, G.E.A.2    Drevon, C.A.3
  • 27
    • 23844475827 scopus 로고    scopus 로고
    • Bile acid modulates transepithelial permeability via the generation of reactive oxygen species in the Caco-2 cell line
    • Araki Y., Katoh T., Ogawa A., et al. Bile acid modulates transepithelial permeability via the generation of reactive oxygen species in the Caco-2 cell line. Free Radic Biol Med 2005, 39:769-780.
    • (2005) Free Radic Biol Med , vol.39 , pp. 769-780
    • Araki, Y.1    Katoh, T.2    Ogawa, A.3
  • 28
    • 70350306941 scopus 로고    scopus 로고
    • Western style diets induce oxidative stress and dysregulate immune responses in the colon in a mouse model of sporadic colon cancer
    • Erdelyi H., Levenkova N., Llin E.I., et al. Western style diets induce oxidative stress and dysregulate immune responses in the colon in a mouse model of sporadic colon cancer. J Nutr 2009, 139:2072-2078.
    • (2009) J Nutr , vol.139 , pp. 2072-2078
    • Erdelyi, H.1    Levenkova, N.2    Llin, E.I.3
  • 29
    • 55849086542 scopus 로고    scopus 로고
    • Intestinal, adipose and liver inflammation in diet-induced obese mice
    • Li H., Lelliott C., Hakansson P., et al. Intestinal, adipose and liver inflammation in diet-induced obese mice. Metabolism 2008, 57:1704-1710.
    • (2008) Metabolism , vol.57 , pp. 1704-1710
    • Li, H.1    Lelliott, C.2    Hakansson, P.3
  • 30
    • 77955845526 scopus 로고    scopus 로고
    • Acute oxidative stress and systemic Nrf2 activation by ketogenic diet
    • Milder J.B, Liang L.-P, Patel M. Acute oxidative stress and systemic Nrf2 activation by ketogenic diet. Neurobiol Dis 2010, 40:238-244.
    • (2010) Neurobiol Dis , vol.40 , pp. 238-244
    • Milder, J.B.1    Liang, L.-P.2    Patel, M.3
  • 31
    • 10044261914 scopus 로고    scopus 로고
    • Long term effects of a ketogenic diet in obese patients
    • Dashti H.M., Hussein T., Asfar S.K., et al. Long term effects of a ketogenic diet in obese patients. Exp Clin Cardiol 2004, 9:200-204.
    • (2004) Exp Clin Cardiol , vol.9 , pp. 200-204
    • Dashti, H.M.1    Hussein, T.2    Asfar, S.K.3
  • 32
    • 33847233644 scopus 로고    scopus 로고
    • Reduced dietary intake of carbohydrates by obese subjects by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces
    • Duncan S.H., Belenguer A., Holtrop G., et al. Reduced dietary intake of carbohydrates by obese subjects by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces. Appl Environ microbial 2007, 1073-1078.
    • (2007) Appl Environ microbial , pp. 1073-1078
    • Duncan, S.H.1    Belenguer, A.2    Holtrop, G.3
  • 33
    • 79251479402 scopus 로고    scopus 로고
    • Diet-induced weight loss reduces colorectal inflammation: implications for colorectal carcinogenesis
    • Pendayala F., Neff L.M., Suares-Farinas M., Holt P.R. Diet-induced weight loss reduces colorectal inflammation: implications for colorectal carcinogenesis. Am J Clin Nutr 2011, 93:234-242.
    • (2011) Am J Clin Nutr , vol.93 , pp. 234-242
    • Pendayala, F.1    Neff, L.M.2    Suares-Farinas, M.3    Holt, P.R.4
  • 34
    • 56049117986 scopus 로고    scopus 로고
    • Butyrylated starch protects colonocyte DNA against dietary protein-induced damage in rats
    • Bajka B.H., Clarke J.M., Cobiac L., Topping D.L. Butyrylated starch protects colonocyte DNA against dietary protein-induced damage in rats. Carcinogenesis 2008, 29:2169-2174.
    • (2008) Carcinogenesis , vol.29 , pp. 2169-2174
    • Bajka, B.H.1    Clarke, J.M.2    Cobiac, L.3    Topping, D.L.4
  • 35
    • 84857833863 scopus 로고    scopus 로고
    • Butyrate attenuates lipopolysaccharide-induced inflammation in intestinal cells and Crohn's mucosa through modulation of antioxidant defense machinery
    • Russo I., Luciani A., De Cicco P., Troncone E., Ciacci C. Butyrate attenuates lipopolysaccharide-induced inflammation in intestinal cells and Crohn's mucosa through modulation of antioxidant defense machinery. Plos One 2012, 7:e32841.
    • (2012) Plos One , vol.7
    • Russo, I.1    Luciani, A.2    De Cicco, P.3    Troncone, E.4    Ciacci, C.5
  • 36
    • 79955492715 scopus 로고    scopus 로고
    • Fecal butyrate levels vary widely among individuals but are usually increased by a diet high in resistant starch
    • McOrist A.L., Miller R.B., Bird A.R., Keogh J.B., Noakes M., Topping D.L., et al. Fecal butyrate levels vary widely among individuals but are usually increased by a diet high in resistant starch. J Nutr 2011, 141:883-889.
    • (2011) J Nutr , vol.141 , pp. 883-889
    • McOrist, A.L.1    Miller, R.B.2    Bird, A.R.3    Keogh, J.B.4    Noakes, M.5    Topping, D.L.6
  • 37
  • 38
    • 0031882108 scopus 로고    scopus 로고
    • Sulfides impair short chain fatty acid beta-oxidation at acylCoA dehydrogenase level in colonocytes. Implications for ulcerative colitis
    • Babidge W., Millard S., Roediger W. Sulfides impair short chain fatty acid beta-oxidation at acylCoA dehydrogenase level in colonocytes. Implications for ulcerative colitis. Mol Cell Biochem 1998, 181:117-124.
    • (1998) Mol Cell Biochem , vol.181 , pp. 117-124
    • Babidge, W.1    Millard, S.2    Roediger, W.3
  • 39
    • 77955630626 scopus 로고    scopus 로고
    • Interactions between gut microbiota host genetics and diet relevant to development of metabolic syndromes in mice
    • Zhang C., Zhang M., Wang S., et al. Interactions between gut microbiota host genetics and diet relevant to development of metabolic syndromes in mice. ISME J 2009, 1-10.
    • (2009) ISME J , pp. 1-10
    • Zhang, C.1    Zhang, M.2    Wang, S.3
  • 40
    • 0038678001 scopus 로고    scopus 로고
    • Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells
    • Cremin J.D., Fitch M.D., Fleming S.E. Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells. Am J Physiol Gastrointest Liver Physiol 2003, 285:G105-G114.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.285
    • Cremin, J.D.1    Fitch, M.D.2    Fleming, S.E.3
  • 41
    • 78650848337 scopus 로고    scopus 로고
    • MTORC1 controls fasting-induced ketogenesis and its modulation by ageing
    • Sangupta S., Peterson T.R., Laplante M., OH S., Sabatini D. mTORC1 controls fasting-induced ketogenesis and its modulation by ageing. Nature 2010, 468:1100-1104.
    • (2010) Nature , vol.468 , pp. 1100-1104
    • Sangupta, S.1    Peterson, T.R.2    Laplante, M.3    OH, S.4    Sabatini, D.5
  • 42
    • 66249088672 scopus 로고    scopus 로고
    • Rapamycin protects against high fat diet-induced obesity in C57BL/6J mice
    • Chang G.R., Chiu Y.-S., Wu Y.Y., et al. Rapamycin protects against high fat diet-induced obesity in C57BL/6J mice. J Pharmacol Sci 2009, 109:496-503.
    • (2009) J Pharmacol Sci , vol.109 , pp. 496-503
    • Chang, G.R.1    Chiu, Y.-S.2    Wu, Y.Y.3
  • 43
    • 0037276069 scopus 로고    scopus 로고
    • A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway
    • Kimura N., Tokunga C., Dalal S., et al. A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway. Genes Cell 2003, 8:65-79.
    • (2003) Genes Cell , vol.8 , pp. 65-79
    • Kimura, N.1    Tokunga, C.2    Dalal, S.3
  • 44
    • 84863413720 scopus 로고    scopus 로고
    • A high fat diet is associated with endotoxemia that originates from the gut
    • Pendyala S., Walker J.M., Holt P.R. A high fat diet is associated with endotoxemia that originates from the gut. Gastroenterology 2012, 142:1100-1101.
    • (2012) Gastroenterology , vol.142 , pp. 1100-1101
    • Pendyala, S.1    Walker, J.M.2    Holt, P.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.