Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State in Cats

Veterinary Clinics of North America - Small Animal Practice

Volumn 43, Issue 2, 2013, Pages 367-379

  Rand, Jacquie S ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Diabetes mellitus; Feline; Hyperosmolar state; Ketoacidosis

Indexed keywords

GLUCOSE; INSULIN; INSULIN DETEMIR; INSULIN GLARGINE; ISOPHANE INSULIN; KETONE; NEUTRAL INSULIN; PHOSPHATE; POTASSIUM;

ACUTE HEMORRHAGIC PANCREATITIS; CAT; CLINICAL FEATURE; DIABETIC KETOACIDOSIS; DIAGNOSTIC PROCEDURE; DRUG EFFICACY; ELECTROLYTE EXCRETION; FLUID RESUSCITATION; FLUID THERAPY; GLUCOSURIA; HYPERGLYCEMIA; HYPEROSMOLAR HYPERGLYCEMIC STATE; KETONURIA; MEDICAL ASSESSMENT; NONHUMAN; OSMOLARITY; POLYDIPSIA; REVIEW; SENSITIVITY AND SPECIFICITY;

ANIMALS; CAT DISEASES; CATS; DIABETES COMPLICATIONS; DIABETES MELLITUS; DIABETIC KETOACIDOSIS; HYPERGLYCEMIA; OSMOLAR CONCENTRATION;

FELIDAE;

EID: 84875594607     PISSN: 01955616     EISSN: 18781306     Source Type: Journal    
DOI: 10.1016/j.cvsm.2013.01.004     Document Type: Review

References (40)

1. Rand J.S., Fleeman L.M., Farrow H.A., et al. Canine and feline diabetes mellitus: nature or nurture?. J Nutr 2004, 134(Suppl 8):2072S-2080S.
2. Nichols R. Complications and concurrent disease associated with diabetes mellitus. Semin Vet Med Surg 1997, 12(4):263-267.
3. Bruskiewicz K., Nelson R., Feldman E., et al. Diabetic ketosis and ketoacidosis in cats: 42 cases (1980-1995). J Am Vet Med Assoc 1997, 211(2):188.
4. Kley S, Casella M, CR. Diabetic ketoacidosis in 22 cats (1997-2002) [abstract]. 12th ECVIM-C. A/ESVIM Congress. Munich (Germany): 2002. http://www.vin.com/ecvim/2002.
5. Marshall R., Rand J., Gunew M., et al. Intramuscular glargine with or without concurrent subcutaneous administration for treatment of feline diabetic ketoacidosis: a preliminary study. Journal of Veterinary Emergency and Critical Care 2013, http://dx.doi.org/10.111/vec.12038.
6. Claus M.A., Silverstein D.C., Shofer F.S., et al. Comparison of regular insulin infusion doses in critically ill diabetic cats: 29 cases (1999-2007). J Vet Emerg Crit Care 2010, 20(5):509-517.
7. Sieber-Ruckstuhl N., Kley S., Tschuor F., et al. Remission of diabetes mellitus in cats with diabetic ketoacidosis. J Vet Intern Med 2008, 22(6):1326-1332.
8. O'Brien M.A. Diabetic emergencies in small animals. Vet Clin North Am Small Anim Pract 2010, 40(2):317.
9. Link KRJ, Allio I, Reinecke M, et al. The effect of experimentally induced chronic hyperglycaemia on serum and pancreatic insulin, pancreatic islet IGF-I and plasma and urinary ketones in domestic cat (Felis felis) Journal of General and Comparative Endocrinology in press March 2013.
10. Niessen S.J., Petrie G., Gaudiano F., et al. Feline acromegaly: an underdiagnosed endocrinopathy?. J Vet Intern Med 2007, 21(5):899-905.
11. Zeugswetter F., Rebuzzi L. Point-of-care β-hydroxybutyrate measurement for the diagnosis of feline diabetic ketoacidaemia. J Small Anim Pract 2012, 53(6):328-331.
12. Weingart C., Lotz F., Kohn B. Validation of a portable hand-held whole-blood ketone meter for use in cats. Vet Clin Pathol 2012, 41(1):114-118.
13. Zeugswetter F., Pagitz M. Ketone measurements using dipstick methodology in cats with diabetes mellitus. J Small Anim Pract 2009, 50(1):4-8.
14. Aroch I., Shechter-Polak M., Segev G. A retrospective study of serum β-hydroxybutyric acid in 215 ill cats: clinical signs, laboratory findings and diagnoses. Vet J 2012, 191(2):240-245.
15. Zeugswetter F., Handl S., Iben C., et al. Efficacy of plasma ß-hydroxybutyrate concentration as a marker for diabetes mellitus in acutely sick cats. J Feline Med Surg 2010, 12(4):300-305.
16. Schermerhorn T., Barr S.C. Relationships between glucose, sodium and effective osmolality in diabetic dogs and cats. J Vet Emerg Crit Care 2006, 16(1):19-24.
17. Koenig A., Drobatz K.J., Beale A.B., et al. Hyperglycemic, hyperosmolar syndrome in feline diabetics: 17 cases (1995-2001). J Vet Emerg Crit Care 2004, 14(1):30-40.
18. Goossens M.M., Nelson R.W., Feldman E.C., et al. Response to insulin treatment and survival in 104 cats with diabetes mellitus (1985-1995). J Vet Intern Med 1998, 12(1):1-6.
19. De Cock H., Forman M., Farver T., et al. Prevalence and histopathologic characteristics of pancreatitis in cats. Vet Pathol 2007, 44(1):39-49.
20. Forman M., Marks S., Cock H., et al. Evaluation of serum feline pancreatic lipase immunoreactivity and helical computed tomography versus conventional testing for the diagnosis of feline pancreatitis. J Vet Intern Med 2004, 18(6):807-815.
21. Forman M., Shiroma J., Armstrong P., et al. Evaluation of feline pancreas-specific lipase (Spec fPL) for the diagnosis of feline pancreatitis. J Vet Intern Med 2009, 23(3):733-734. [ACVIM abstract 165].
22. Zoran D.L. Pancreatitis in cats: diagnosis and management of a challenging disease. J Am Anim Hosp Assoc 2006, 42(1):1-9.
23. Panciera D. Fluid therapy in endocrine and metabolic disorders. Fluid, electrolyte and acid-base disorders in small animal practice 2006, Saunders, Philadelphia, p. 478-89. 3rd edition.
24. Stowe M.L. Plasma-Lyte vs. normal saline: preventing hyperchloremic acidosis in fluid resuscitation for diabetic ketoacidosis. MSc thesis 2012, 2012. http://commons.pacificu.edu/pa/296.
25. Kraus M., Calvert C., Jacobs G., et al. Feline diabetes mellitus: a retrospective mortality study of 55 cats (1982-1994). J Am Anim Hosp Assoc 1997, 33(2):107-111.
26. Roomp K., Rand J. Intensive blood glucose control is safe and effective in diabetic cats using home monitoring and treatment with glargine. J Feline Med Surg 2009, 11(8):668-682.
27. Peterson M.E., Taylor R.S., Greco D.S., et al. Acromegaly in 14 cats. J Vet Intern Med 1990, 4(4):192-201.
28. Little C., Gettinby G. Heart failure is common in diabetic cats: findings from a retrospective case-controlled study in first-opinion practice. J Small Anim Pract 2008, 49(1):17-25.
29. Monaghan K., Nolan B., Labato M. Feline acute kidney injury 2. Approach to diagnosis, treatment and prognosis. J Feline Med Surg 2012, 14(11):785-793.
30. Kerl M.E. Diabetic ketoacidosis: treatment recommendations. Compend Contin Educ Vet 2001, 23(4):330-340.
31. Marshall R.D., Rand J.S., Morton J.M. Glargine and protamine zinc insulin have a longer duration of action and result in lower mean daily glucose concentrations than lente insulin in healthy cats. J Vet Pharmacol Ther 2008, 31:205-212.
32. Adams L.G., Hardy R.M., Weiss D.J., et al. Hypophosphatemia and hemolytic anemia associated with diabetes mellitus and hepatic lipidosis in cats. J Vet Intern Med 1993, 7(5):266-271.
33. Macintire D.K. Emergency therapy of diabetic crises: insulin overdose, diabetic ketoacidosis, and hyperosmolar coma. Vet Clin North Am Small Anim Pract 1995, 25:639-650.
34. Wiener R.S., Wiener D.C., Larson R.J. Benefits and risks of tight glucose control in critically ill adults. JAMA 2008, 300(8):933-944.
35. Feldman E., Nelson R. Diabetic ketoacidosis. Canine and feline endocrinology and reproduction 2004, WB Saunders Co, St Louis (MO), p. 580-615. 3rd edition.
36. Chastain C., Nichols C. Low-dose intramuscular insulin therapy for diabetic ketoacidosis in dogs. J Am Vet Med Assoc 1981, 178(6):561-564.
37. Rand J.S., Marshall R.D. Diabetes mellitus in cats. Vet Clin North Am Small Anim Pract 2005, 35(1):211.
38. Scholtz H., Pretorius S., Wessels D., et al. Equipotency of insulin glargine and regular human insulin on glucose disposal in healthy subjects following intravenous infusion. Acta Diabetol 2003, 40(4):156-162.
39. Umpierrez G.E., Jones S., Smiley D., et al. Insulin analogs versus human insulin in the treatment of patients with diabetic ketoacidosis: a randomized controlled trial. Diabetes Care 2009, 32(7):1164-1169.
40. Shankar V., Haque A., Churchwell K.B., et al. Insulin glargine supplementation during early management phase of diabetic ketoacidosis in children. Intensive Care Med 2007, 33(7):1173-1178.