A structural and molecular dynamics approach to understanding the peptide-receptive transition state of MHC-I molecules

Molecular Immunology

Volumn 55, Issue 2, 2013, Pages 123-125

  Mage, Michael G ^a   Dolan, Michael A ^a   Wang, Rui ^a   Boyd, Lisa F ^a   Revilleza, Maria Jamela ^a   Robinson, Howard ^b   Natarajan, Kannan ^a   Myers, Nancy B ^c   Hansen, Ted H ^c   Margulies, David H ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antigen presentation; MHC I structure and function; Molecular dynamics; Peptide loading; X ray crystallography

Indexed keywords

AMINO ACID; CHAPERONE; MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ANTIGEN PRESENTATION; CD8+ T LYMPHOCYTE; CELL SURFACE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENDOPLASMIC RETICULUM; ENDOSOME; HYDROGEN BOND; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULE; PRIORITY JOURNAL; PROTEIN STRUCTURE; REVIEW; X RAY DIFFRACTION;

ANTIBODIES, MONOCLONAL; ANTIGEN PRESENTATION; CD8-POSITIVE T-LYMPHOCYTES; CRYSTALLOGRAPHY, X-RAY; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, PATTERN RECOGNITION;

EID: 84875593289     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2012.10.021     Document Type: Review

References (6)

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