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Volumn 519, Issue 2, 2013, Pages 251-259

Distinct function of P63 isoforms during embryonic skeletal development

Author keywords

Col10a1; Col2a1; Embryonic skeletal development; P63 isoforms; Transgenic mice

Indexed keywords

COLLAGEN 10A1; COLLAGEN TYPE 10; ISOPROTEIN; NP63 ALPHA; PROTEIN P63; TAP63 ALPHA; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG;

EID: 84875583877     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2013.02.021     Document Type: Article
Times cited : (11)

References (33)
  • 1
    • 0036830491 scopus 로고    scopus 로고
    • The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
    • Akiyama H., Chaboissier M.C., Martin J.F., Schedl A., de Crombrugghe B. The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev. 2001, 16(21):2813-2828.
    • (2001) Genes Dev. , vol.16 , Issue.21 , pp. 2813-2828
    • Akiyama, H.1    Chaboissier, M.C.2    Martin, J.F.3    Schedl, A.4    de Crombrugghe, B.5
  • 2
    • 60349120776 scopus 로고    scopus 로고
    • Genetic diseases of connective tissues: cellular and extracellular effects of ECM mutations
    • Bateman J.F., Boot-Handford R.P., Lamandé S.R. Genetic diseases of connective tissues: cellular and extracellular effects of ECM mutations. Nat. Rev. Genet. 2009, 10(3):173-183. 10.1038/nrg2520.
    • (2009) Nat. Rev. Genet. , vol.10 , Issue.3 , pp. 173-183
    • Bateman, J.F.1    Boot-Handford, R.P.2    Lamandé, S.R.3
  • 3
    • 84864192630 scopus 로고    scopus 로고
    • Role of p63 in Development, Tumorigenesis and Cancer Progression
    • (Epub 2012 Jul 31)
    • Bergholz J., Xiao Z.X. Role of p63 in Development, Tumorigenesis and Cancer Progression. Cancer Microenviron. 2012, 5(3):311-322. (Epub 2012 Jul 31). 10.1007/s12307-012-0116-9.
    • (2012) Cancer Microenviron. , vol.5 , Issue.3 , pp. 311-322
    • Bergholz, J.1    Xiao, Z.X.2
  • 4
    • 0035810951 scopus 로고    scopus 로고
    • Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization
    • (Epub 2001 May 22)
    • Bi W., et al. Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization. Proc. Natl. Acad. Sci. U. S. A. 2001, 98(12):6698-6703. (Epub 2001 May 22).
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , Issue.12 , pp. 6698-6703
    • Bi, W.1
  • 5
    • 33847023954 scopus 로고    scopus 로고
    • TAp63 and DeltaNp63 in cancer and epidermal development
    • (Epub 2007 Feb 3)
    • Candi E., et al. TAp63 and DeltaNp63 in cancer and epidermal development. Cell Cycle 2007, 6(3):274-285. (Epub 2007 Feb 3).
    • (2007) Cell Cycle , vol.6 , Issue.3 , pp. 274-285
    • Candi, E.1
  • 6
    • 77958108690 scopus 로고    scopus 로고
    • SOX9 determines RUNX2 transactivity by directing intracellular degradation
    • Cheng A., Genever P.G. SOX9 determines RUNX2 transactivity by directing intracellular degradation. J. Bone Miner. Res. 2010, 25:2404-2013.
    • (2010) J. Bone Miner. Res. , vol.25 , pp. 2404-2013
    • Cheng, A.1    Genever, P.G.2
  • 7
    • 0035574614 scopus 로고    scopus 로고
    • Regulatory mechanisms in the pathways of cartilage and bone formation
    • (Review)
    • de Crombrugghe B., Lefebvre V., Nakashima K. Regulatory mechanisms in the pathways of cartilage and bone formation. Curr. Opin. Cell Biol. 2001, 13(6):721-727. (Review).
    • (2001) Curr. Opin. Cell Biol. , vol.13 , Issue.6 , pp. 721-727
    • de Crombrugghe, B.1    Lefebvre, V.2    Nakashima, K.3
  • 8
    • 84862537126 scopus 로고    scopus 로고
    • Targeting Runx2 expression in hypertrophic chondrocytes impairs endochondral ossification during early skeletal development
    • Ding M., et al. Targeting Runx2 expression in hypertrophic chondrocytes impairs endochondral ossification during early skeletal development. J. Cell. Physiol. 2012, 227(10):3446-3456. 10.1002/jcp.24045.
    • (2012) J. Cell. Physiol. , vol.227 , Issue.10 , pp. 3446-3456
    • Ding, M.1
  • 9
    • 77950345356 scopus 로고    scopus 로고
    • SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification
    • Hattori T., et al. SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification. Development 2010, 137:901-911.
    • (2010) Development , vol.137 , pp. 901-911
    • Hattori, T.1
  • 10
    • 3142702789 scopus 로고    scopus 로고
    • Coat color-tagged green mouse with EGFP expressed from the RNA polymerase II promoter
    • Hsiao Y.C., et al. Coat color-tagged green mouse with EGFP expressed from the RNA polymerase II promoter. Genesis 2004, 39(2):122-129.
    • (2004) Genesis , vol.39 , Issue.2 , pp. 122-129
    • Hsiao, Y.C.1
  • 11
    • 0942301281 scopus 로고    scopus 로고
    • P63 is the molecular switch for initiation of an epithelial stratification program
    • (Epub 2004 Jan 16)
    • Koster M.I., Kim S., Mills A.A., DeMayo F.J., Roop D.R. p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev. 2004, 18(2):126-131. (Epub 2004 Jan 16).
    • (2004) Genes Dev. , vol.18 , Issue.2 , pp. 126-131
    • Koster, M.I.1    Kim, S.2    Mills, A.A.3    DeMayo, F.J.4    Roop, D.R.5
  • 12
    • 0034079520 scopus 로고    scopus 로고
    • The p53/p63/p73 family of transcription factors: overlapping and distinct functions
    • Levrero M., De Laurenzi V., Costanzo A., Gong J., Wang J.Y., Melino G. The p53/p63/p73 family of transcription factors: overlapping and distinct functions. J. Cell Sci. 2000, 113(Pt. 10):1661-1670.
    • (2000) J. Cell Sci. , vol.113 , Issue.PART. 10 , pp. 1661-1670
    • Levrero, M.1    De Laurenzi, V.2    Costanzo, A.3    Gong, J.4    Wang, J.Y.5    Melino, G.6
  • 13
    • 84862778169 scopus 로고    scopus 로고
    • Putative function of TAP63α during endochondral bone formation
    • (Epub 2012 Jan 5)
    • Li F., et al. Putative function of TAP63α during endochondral bone formation. Gene 2012, 495(2):95-103. (Epub 2012 Jan 5).
    • (2012) Gene , vol.495 , Issue.2 , pp. 95-103
    • Li, F.1
  • 14
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 15
    • 70350674206 scopus 로고    scopus 로고
    • Identification and functional characterization of two new transcriptional variants of the human p63 gene
    • (Epub 2009 Aug 21)
    • Mangiulli M., et al. Identification and functional characterization of two new transcriptional variants of the human p63 gene. Nucleic Acids Res. 2009, 37(18):6092-6104. (Epub 2009 Aug 21).
    • (2009) Nucleic Acids Res. , vol.37 , Issue.18 , pp. 6092-6104
    • Mangiulli, M.1
  • 16
    • 0033594491 scopus 로고    scopus 로고
    • P63 is a p53 homologue required for limb and epidermal morphogenesis
    • Mills A.A., Zheng B., Wang X.J., Vogel H., Roop D.R., Bradley A. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 1999, 398(6729):708-713.
    • (1999) Nature , vol.398 , Issue.6729 , pp. 708-713
    • Mills, A.A.1    Zheng, B.2    Wang, X.J.3    Vogel, H.4    Roop, D.R.5    Bradley, A.6
  • 17
    • 3543110350 scopus 로고    scopus 로고
    • P63 and p73: roles in development and tumor formation
    • Moll U.M., Slade N. p63 and p73: roles in development and tumor formation. Mol. Cancer Res. 2004, 2(7):371-386.
    • (2004) Mol. Cancer Res. , vol.2 , Issue.7 , pp. 371-386
    • Moll, U.M.1    Slade, N.2
  • 18
    • 0037097976 scopus 로고    scopus 로고
    • FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease
    • Ornitz D.M., Marie P.J. FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease. Genes Dev. 2002, 16(12):1446-1465.
    • (2002) Genes Dev. , vol.16 , Issue.12 , pp. 1446-1465
    • Ornitz, D.M.1    Marie, P.J.2
  • 19
    • 0030666372 scopus 로고    scopus 로고
    • Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
    • Otto F., et al. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 1997, 89:765-771.
    • (1997) Cell , vol.89 , pp. 765-771
    • Otto, F.1
  • 20
    • 65749098589 scopus 로고    scopus 로고
    • Alcian blue/alizarin red staining of cartilage and bone in mouse
    • (pdb.prot5170)
    • Ovchinnikov D. Alcian blue/alizarin red staining of cartilage and bone in mouse. Cold Spring Harb. Protoc. 2009, 3. (pdb.prot5170).
    • (2009) Cold Spring Harb. Protoc. , vol.3
    • Ovchinnikov, D.1
  • 21
    • 40549104468 scopus 로고    scopus 로고
    • Properties of the six isoforms of p63: p53-like regulation in response to genotoxic stress and cross talk with DeltaNp73
    • (Epub 2007 Nov 28)
    • Petitjean A., et al. Properties of the six isoforms of p63: p53-like regulation in response to genotoxic stress and cross talk with DeltaNp73. Carcinogenesis 2008, 29(2):273-281. (Epub 2007 Nov 28).
    • (2008) Carcinogenesis , vol.29 , Issue.2 , pp. 273-281
    • Petitjean, A.1
  • 22
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001, 29:e45.
    • (2001) Nucleic Acids Res. , vol.29
    • Pfaffl, M.W.1
  • 23
    • 84856188471 scopus 로고    scopus 로고
    • δNp63 knockout mice reveal its indispensable role as a master regulator of epithelial
    • Romano R.A., et al. δNp63 knockout mice reveal its indispensable role as a master regulator of epithelial. Development 2012, 139(4):772-782.
    • (2012) Development , vol.139 , Issue.4 , pp. 772-782
    • Romano, R.A.1
  • 24
    • 80054878182 scopus 로고    scopus 로고
    • TAp63 is important for cardiac differentiation of embryonic stem cells and heart Development
    • Rouleau M., et al. TAp63 is important for cardiac differentiation of embryonic stem cells and heart Development. Stem Cells 2011, 29(11):1672-1683. 10.1002/stem.723.
    • (2011) Stem Cells , vol.29 , Issue.11 , pp. 1672-1683
    • Rouleau, M.1
  • 25
    • 0034892604 scopus 로고    scopus 로고
    • P63 Gene mutations in EEC syndrome, limb-mammary syndrome, and isolated split hand-split foot malformation suggest a genotype-phenotype correlation
    • (Epub 2001 Jul 17)
    • van Bokhoven H., et al. p63 Gene mutations in EEC syndrome, limb-mammary syndrome, and isolated split hand-split foot malformation suggest a genotype-phenotype correlation. Am. J. Hum. Genet. 2001, 69(3):481-492. (Epub 2001 Jul 17).
    • (2001) Am. J. Hum. Genet. , vol.69 , Issue.3 , pp. 481-492
    • van Bokhoven, H.1
  • 26
    • 0037507296 scopus 로고    scopus 로고
    • DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development
    • Wu G., et al. DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development. Cancer Res. 2003, 15;63(10):2351-2357.
    • (2003) Cancer Res. , Issue.10 , pp. 2351-2357
    • Wu, G.1
  • 27
    • 13444250890 scopus 로고    scopus 로고
    • DeltaNp63alpha up-regulates the Hsp70 gene in human cancer
    • Wu G., et al. DeltaNp63alpha up-regulates the Hsp70 gene in human cancer. Cancer Res. 2005, 65(3):758-766.
    • (2005) Cancer Res. , vol.65 , Issue.3 , pp. 758-766
    • Wu, G.1
  • 28
    • 41849131480 scopus 로고    scopus 로고
    • Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin
    • Wu Q., Chen D., Zuscik M.J., O'Keefe R.J., Rosier R.N. Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J. Bone Miner. Res. 2008, 23(4):552-563.
    • (2008) J. Bone Miner. Res. , vol.23 , Issue.4 , pp. 552-563
    • Wu, Q.1    Chen, D.2    Zuscik, M.J.3    O'Keefe, R.J.4    Rosier, R.N.5
  • 29
    • 0033594485 scopus 로고    scopus 로고
    • P63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
    • Yang A., et al. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 1999, 398(6729):714-718.
    • (1999) Nature , vol.398 , Issue.6729 , pp. 714-718
    • Yang, A.1
  • 30
    • 66349137046 scopus 로고    scopus 로고
    • Localization of the cis-enhancer element for mouse type X collagen expression in hypertrophic chondrocytes in vivo
    • Zheng Q., et al. Localization of the cis-enhancer element for mouse type X collagen expression in hypertrophic chondrocytes in vivo. J. Bone Miner. Res. 2009, 24:1022-1032.
    • (2009) J. Bone Miner. Res. , vol.24 , pp. 1022-1032
    • Zheng, Q.1
  • 31
    • 0029558172 scopus 로고
    • A 182bp fragment of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte expression in transgenic mice
    • Zhou G., et al. A 182bp fragment of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte expression in transgenic mice. J. Cell Sci. 1995, (Pt. 12):3677-3684.
    • (1995) J. Cell Sci. , Issue.PART. 12 , pp. 3677-3684
    • Zhou, G.1
  • 32
    • 34447500094 scopus 로고    scopus 로고
    • Dominance of SOX9 function over RUNX2 during skeletogenesis
    • Zhou G., et al. Dominance of SOX9 function over RUNX2 during skeletogenesis. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:19004-19009.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 19004-19009
    • Zhou, G.1
  • 33
    • 0032978712 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
    • Zufferey R., Donello J.E., Trono D., Hope T.J. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J. Virol. 1999, 73(4):2886-2892.
    • (1999) J. Virol. , vol.73 , Issue.4 , pp. 2886-2892
    • Zufferey, R.1    Donello, J.E.2    Trono, D.3    Hope, T.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.