메뉴 건너뛰기




Volumn 48, Issue 3, 2013, Pages 352-357

The role of Kupffer cells in the morphogenesis of nonalcoholic steatohepatitis-ultrastructural findings. the first report in pediatric patients

Author keywords

Activated Kupffer cells macrophages; Erythrophagocytosis; Fibrosis; Hepatic nonparenchymal cells; Morphogenesis of pediatric nonalcoholic steatohepatitis; Ultrastructure

Indexed keywords

GLUTARALDEHYDE; PARAFORMALDEHYDE;

EID: 84875530122     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2012.746390     Document Type: Article
Times cited : (28)

References (35)
  • 1
    • 63349106888 scopus 로고    scopus 로고
    • Portal chronic inflammation in nonalcoholic liver disease (NAFLD): A histologic marker of advanced NAFLD-Clinicopathologic correlations from the nonalcoholic steatohepatitis clinical research network
    • Brunt EM, Kleiner DE, Wilson LA, Unalp A, Behling CE, Lavine JE, et al. Portal chronic inflammation in nonalcoholic liver disease (NAFLD): a histologic marker of advanced NAFLD-Clinicopathologic correlations from the nonalcoholic steatohepatitis clinical research network. Hepatology 2009;49:809-20.
    • (2009) Hepatology , vol.49 , pp. 809-820
    • Brunt, E.M.1    Kleiner, D.E.2    Wilson, L.A.3    Unalp, A.4    Behling, C.E.5    Lavine, J.E.6
  • 2
    • 0036302288 scopus 로고    scopus 로고
    • Expanding the natural history of nonalcoholic steatohepatitis: From cryptogenic cirrhosis to hepato-cellular carcinoma
    • Bugianesi E, Leone N, Vanni E, Marchesini G, Brunello F, Carucci P, et al. Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepato-cellular carcinoma. Gastroentetrology 2002;123:134-40.
    • (2002) Gastroentetrology , vol.123 , pp. 134-140
    • Bugianesi, E.1    Leone, N.2    Vanni, E.3    Marchesini, G.4    Brunello, F.5    Carucci, P.6
  • 3
    • 73149109067 scopus 로고    scopus 로고
    • Hypoxia and non alcoholic fatty liver disease
    • Byrne CD. Hypoxia and non alcoholic fatty liver disease. Clin Sci (Lond) 2009;118:397-400.
    • (2009) Clin Sci (Lond) , vol.118 , pp. 397-400
    • Byrne, C.D.1
  • 4
    • 56649083495 scopus 로고    scopus 로고
    • Mechanisms of disease progression in nonalcoholic fatty liver disease
    • Jou J, Choi SS, Diehl AM. Mechanisms of disease progression in nonalcoholic fatty liver disease. Semin Liver Dis 2008; 28:370-9.
    • (2008) Semin Liver Dis , vol.28 , pp. 370-379
    • Jou, J.1    Choi, S.S.2    Diehl, A.M.3
  • 5
    • 79952361224 scopus 로고    scopus 로고
    • Physical activity recommendations, exercise intensity, and histological severity of nonalcoholic fatty liver disease
    • Kistler KD, Brunt EM, Clark JM, Diehl AM, Sallis JF, Schwimmer JB, et al. Physical activity recommendations, exercise intensity, and histological severity of nonalcoholic fatty liver disease. Am J Gastroenterol 2011;106:460-8.
    • (2011) Am J Gastroenterol , vol.106 , pp. 460-468
    • Kistler, K.D.1    Brunt, E.M.2    Clark, J.M.3    Diehl, A.M.4    Sallis, J.F.5    Schwimmer, J.B.6
  • 8
    • 70349773095 scopus 로고    scopus 로고
    • Histopathology of non-alcoholic fatty liver disease
    • Brunt EM. Histopathology of non-alcoholic fatty liver disease. Clin Liver Dis 2009;13:533-44.
    • (2009) Clin Liver Dis , vol.13 , pp. 533-544
    • Brunt, E.M.1
  • 9
  • 10
    • 77956119396 scopus 로고    scopus 로고
    • Simple non-invasive fibrosis scoring systems can reliably exclude advanced fibrosis in patients with non-alcoholic fatty liver disease
    • McPherson S, Stewart SF, Henderson E, Burt AD, Day CP. Simple non-invasive fibrosis scoring systems can reliably exclude advanced fibrosis in patients with non-alcoholic fatty liver disease. Gut 2010;59:1265-9.
    • (2010) Gut , vol.59 , pp. 1265-1269
    • McPherson, S.1    Stewart, S.F.2    Henderson, E.3    Burt, A.D.4    Day, C.P.5
  • 12
    • 0038118138 scopus 로고    scopus 로고
    • Ultrastructure of hepatocyte mitochondria in nonalcoholic steatohepatitis in pediatric patients: Usefulness of electron microscopy in the diagnosis of the disease
    • Sobaniec-Lotowska ME, Lebensztejn DM. Ultrastructure of hepatocyte mitochondria in nonalcoholic steatohepatitis in pediatric patients: usefulness of electron microscopy in the diagnosis of the disease. Am J Gastroenterol 2003;98: 1664-5.
    • (2003) Am J Gastroenterol , vol.98 , pp. 1664-1665
    • Sobaniec-Lotowska, M.E.1    Lebensztejn, D.M.2
  • 15
    • 77958468753 scopus 로고    scopus 로고
    • A novel non-alcoholic steatohepatitis animal model featured with insulin resistance, hepatic inflammation and fibrosis
    • Zhao J, Zhou G, Li M, Li W, Lü J, Xiong L, et al. A novel non-alcoholic steatohepatitis animal model featured with insulin resistance, hepatic inflammation and fibrosis. Scand J Gastroenterol 2010;45:1360-71.
    • (2010) Scand J Gastroenterol , vol.45 , pp. 1360-1371
    • Zhao, J.1    Zhou, G.2    Li, M.3    Li, W.4    Lü, J.5    Xiong, L.6
  • 16
    • 0035258553 scopus 로고    scopus 로고
    • The role of Kupffer cells in non-alcoholic steatohepatitis of rats chronically fed with high-fat diet
    • Fan J, Zhong L, Wang G, Wu X, Jing D, Zhang P. The role of Kupffer cells in non-alcoholic steatohepatitis of rats chronically fed with high-fat diet. Zhonghua Gan Zang Bing Za Zhi 2001;9:16-18.
    • (2001) Zhonghua Gan Zang Bing Za Zhi , vol.9 , pp. 16-18
    • Fan, J.1    Zhong, L.2    Wang, G.3    Wu, X.4    Jing, D.5    Zhang, P.6
  • 17
    • 34249810078 scopus 로고    scopus 로고
    • Role of oxidative stress and Kupffer cells in hepatic fibrosis
    • Kawada N, Otogawa K. Role of oxidative stress and Kupffer cells in hepatic fibrosis. J Gastroenterol Hepatol 2007;22: S85-6.
    • (2007) J Gastroenterol Hepatol , vol.22
    • Kawada, N.1    Otogawa, K.2
  • 18
    • 38449093343 scopus 로고    scopus 로고
    • Effect of high fat diet on the volume of liver and quantitative feature of Kupffer cells in the female rat: A stereological and ultrastructural study
    • Kiki I, Altunkaynak BZ, Altunkaynak ME, Vuraler O, Unal D, Kaplan S. Effect of high fat diet on the volume of liver and quantitative feature of Kupffer cells in the female rat: a stereological and ultrastructural study. Obes Surg 2007; 17:1381-8.
    • (2007) Obes Surg , vol.17 , pp. 1381-1388
    • Kiki, I.1    Altunkaynak, B.Z.2    Altunkaynak, M.E.3    Vuraler, O.4    Unal, D.5    Kaplan, S.6
  • 19
    • 34247844680 scopus 로고    scopus 로고
    • Erythrophagocytosis by liver macrophages (Kupffer cells) promotes oxidative stress, inflammation, and fibrosis in a rabbit model of steatohepatitis: Implications for the pathogenesis of human nonalcoholic steatohepatitis
    • Otogawa K, Kinoshita K, Fujii H, Sakabe M, Shiga R, Nakatani K, et al. Erythrophagocytosis by liver macrophages (Kupffer cells) promotes oxidative stress, inflammation, and fibrosis in a rabbit model of steatohepatitis: implications for the pathogenesis of human nonalcoholic steatohepatitis. Am J Pathol 2007;170:967-80.
    • (2007) Am J Pathol , vol.170 , pp. 967-980
    • Otogawa, K.1    Kinoshita, K.2    Fujii, H.3    Sakabe, M.4    Shiga, R.5    Nakatani, K.6
  • 20
    • 34249780405 scopus 로고    scopus 로고
    • Central role of mitochondria in metabolic regulation of liver pathophysiology
    • Sato N. Central role of mitochondria in metabolic regulation of liver pathophysiology. J Gastroenterol Hepatol 2007;22: S1-6.
    • (2007) J Gastroenterol Hepatol , vol.22
    • Sato, N.1
  • 21
    • 33144463511 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice
    • Tomita K, Tamiya G, Ando S, Ohsumi K, Chiyo T, Mizutani A, et al. Tumour necrosis factor alpha signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice. Gut 2006;55:415-24.
    • (2006) Gut , vol.55 , pp. 415-424
    • Tomita, K.1    Tamiya, G.2    Ando, S.3    Ohsumi, K.4    Chiyo, T.5    Mizutani, A.6
  • 22
    • 49649110937 scopus 로고    scopus 로고
    • Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
    • Wouters K, van Gorp PJ, Bieghs V, Gijbels MJ, Duimel H, Lütjohann D, et al. Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis. Hepatology 2008;48:474-86.
    • (2008) Hepatology , vol.48 , pp. 474-486
    • Wouters, K.1    Van Gorp, P.J.2    Bieghs, V.3    Gijbels, M.J.4    Duimel, H.5    Lütjohann, D.6
  • 25
    • 33747751924 scopus 로고    scopus 로고
    • Chitotriosidase gene expression in Kupffer cells from patients with non-alcoholic fatty liver disease
    • Malaguarnera L, Di Rosa M, Zambito AM, dell'Ombra N, Nicoletti F, Malaguarnera M. Chitotriosidase gene expression in Kupffer cells from patients with non-alcoholic fatty liver disease. Gut 2006;55:1313-20.
    • (2006) Gut , vol.55 , pp. 1313-1320
    • Malaguarnera, L.1    Di Rosa, M.2    Zambito, A.M.3    Dell'Ombra, N.4    Nicoletti, F.5    Malaguarnera, M.6
  • 26
    • 33947261669 scopus 로고    scopus 로고
    • Predictors reflecting the pathological severity of non-alcoholic fatty liver disease: Comprehensive study of clinical and immunohisto-chemical findings in younger Asian patients
    • Park JW, Jeong G, Kim SJ, Kim MK, Park SM. Predictors reflecting the pathological severity of non-alcoholic fatty liver disease: comprehensive study of clinical and immunohisto-chemical findings in younger Asian patients. J Gastroenterol Hepatol 2007;22:461-3.
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. 461-463
    • Park, J.W.1    Jeong, G.2    Kim, S.J.3    Kim, M.K.4    Park, S.M.5
  • 27
    • 69249233513 scopus 로고    scopus 로고
    • Role of hepatic iron in non-alcoholic steatohepatitis
    • Sumida Y, Yoshikawa T, Okanoue T. Role of hepatic iron in non-alcoholic steatohepatitis. Hepatol Res 2009;39:213-22.
    • (2009) Hepatol Res , vol.39 , pp. 213-222
    • Sumida, Y.1    Yoshikawa, T.2    Okanoue, T.3
  • 28
    • 80052661748 scopus 로고    scopus 로고
    • Iron overload in nonalcoholic steatohe-patitis
    • Fujita N, Takei Y. Iron overload in nonalcoholic steatohe-patitis. Adv Clin Chem 2011;55:105-32.
    • (2011) Adv Clin Chem , vol.55 , pp. 105-132
    • Fujita, N.1    Takei, Y.2
  • 29
    • 51549116759 scopus 로고    scopus 로고
    • The obesity epidemic and nonalcoholic fatty liver disease in children
    • Dunn W, Schwimmer JB. The obesity epidemic and nonalcoholic fatty liver disease in children. Curr Gastroenterol Rep 2008;10:67-72.
    • (2008) Curr Gastroenterol Rep , vol.10 , pp. 67-72
    • Dunn, W.1    Schwimmer, J.B.2
  • 30
    • 73349119128 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease in children living in the obeseogenic society
    • Hesham A-Kader H. Nonalcoholic fatty liver disease in children living in the obeseogenic society. World J Pediatr 2009;5:245-54.
    • (2009) World J Pediatr , vol.5 , pp. 245-254
    • Hesham A-Kader, H.1
  • 31
    • 57249103570 scopus 로고    scopus 로고
    • Nonalcoholic Steatohepatitis Clinical Research Network. Clinical correlations of histopa-thology in pediatric nonalcoholic steatohepatitis
    • Patton HM, Lavine JE, Van Natta ML, Schwinmmer JB, Kleiner D, Molleston J. Nonalcoholic Steatohepatitis Clinical Research Network. Clinical correlations of histopa-thology in pediatric nonalcoholic steatohepatitis. Gastroen-terology 2008;135:1961-71.
    • (2008) Gastroen-terology , vol.135 , pp. 1961-1971
    • Patton, H.M.1    Lavine, J.E.2    Van Natta, M.L.3    Schwinmmer, J.B.4    Kleiner, D.5    Molleston, J.6
  • 32
    • 77956339546 scopus 로고    scopus 로고
    • Association between metabolic syndrome and liver histology among children with nonalcoholic fatty liver disease
    • Patton HM, Yates K, Unalp-Arida A, Behling CA, Huang TT, Rosenthal P, et al. Association between metabolic syndrome and liver histology among children with nonalcoholic fatty liver disease. Am J Gastroenterol 2010; 105:2093-102.
    • (2010) Am J Gastroenterol , vol.105 , pp. 2093-2102
    • Patton, H.M.1    Yates, K.2    Unalp-Arida, A.3    Behling, C.A.4    Huang, T.T.5    Rosenthal, P.6
  • 33
    • 21344475102 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease (NAFLD) in children
    • Roberts EA. Non-alcoholic fatty liver disease (NAFLD) in children. Front Biosci 2005;10:2306-18.
    • (2005) Front Biosci , vol.10 , pp. 2306-2318
    • Roberts, E.A.1
  • 35
    • 84898837904 scopus 로고    scopus 로고
    • The role of Kupffer cells in the pathogenesis of non-alcoholic steatohepatitis: Immunohistochemical and ultrastructural findings in pediatric patients
    • Munich/Germany, February 8-9
    • Sobaniec-Lotowska ME, Lotowska JM. The role of Kupffer cells in the pathogenesis of non-alcoholic steatohepatitis: immunohistochemical and ultrastructural findings in pediatric patients. Falk Symposium 181, Munich/Germany, February 8-9, 2012;28.
    • (2012) Falk Symposium , vol.181 , pp. 28
    • Sobaniec-Lotowska, M.E.1    Lotowska, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.