Performance status during and after radiotherapy plus concomitant and adjuvant temozolomide in elderly patients with glioblastoma multiforme

Journal of Clinical Neuroscience

Volumn 20, Issue 4, 2013, Pages 503-508

  Lee, Jeong Heon ^a   Jung, Tae Young ^a   Jung, Shin ^a   Kim, In Young ^a   Jang, Woo Youl ^a   Moon, Kyung Sub ^a   Jeong, Eun Hui ^b  

^a Chonnam National University Hwasun Hospital and Medical School   (South Korea)

^b Chonnam National University   (South Korea)

Author keywords

Concomitant; Elderly; Glioblastoma multiforme; Performance; Prognosis; Radiotherapy; Temozolomide

Indexed keywords

TEMOZOLOMIDE;

ADJUVANT THERAPY; AGE; AGED; ARTICLE; BRAIN SURGERY; CANCER GRADING; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CLINICAL ARTICLE; DIARRHEA; DRUG DOSE INCREASE; ELDERLY CARE; FEMALE; GENERAL CONDITION DETERIORATION; GLIOBLASTOMA; HUMAN; INFECTION; LEUKOPENIA; MALE; MULTIPLE CYCLE TREATMENT; NEUTROPENIA; OVERALL SURVIVAL; PNEUMONIA; PRIORITY JOURNAL; THROMBOCYTOPENIA; TREATMENT OUTCOME;

AGED; ANTINEOPLASTIC AGENTS, ALKYLATING; BRAIN NEOPLASMS; CHEMORADIOTHERAPY, ADJUVANT; DACARBAZINE; FEMALE; GLIOBLASTOMA; HUMANS; KAPLAN-MEIER ESTIMATE; KARNOFSKY PERFORMANCE STATUS; MALE; PROGNOSIS; RADIOTHERAPY; TREATMENT OUTCOME;

EID: 84875528013     PISSN: 09675868     EISSN: 15322653     Source Type: Journal    
DOI: 10.1016/j.jocn.2012.03.044     Document Type: Article

References (15)

1. A. Fleury, F. Menegoz, and P. Grosclaude Descriptive epidemiology of cerebral gliomas in France Cancer 79 1997 1195 1202
2. I. Chakrabarti, M. Cockburn, and W. Cozen A population-based description of glioblastoma multiforme in Los Angeles County, 1974-1999 Cancer 104 2005 2798 2806
3. A.A. Brandes, A. Compostella, and V. Blatt Glioblastoma in the elderly: current and future trends Crit Rev Oncol Hematol 60 2006 256 266
4. R. Stupp, W.P. Mason, and M.J. van den Bent Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma N Engl J Med 352 2005 987 996
5. G. Minniti, V. De Sanctis, and R. Muni Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma in elderly patients J Neurooncol 88 2008 97 103
6. S.E. Combs, J. Wagner, and M. Bischof Postoperative treatment of primary glioblastoma multiforme with radiation and concomitant temozolomide in elderly patients Int J Radiat Oncol Biol Phys 70 2008 987 992
7. A.A. Brandes, E. Franceschi, and A. Tosoni Temozolomide concomitant and adjuvant to radiotherapy in elderly patients with glioblastoma correlation with MGMT promoter methylation status Cancer 115 2009 3512 3518
8. F. Fiorica, M. Berretta, and C. Colosimo Glioblastoma in elderly patients: safety and efficacy of adjuvant radiotherapy with concomitant temozolomide Arch Gerontol Geriatr 51 2010 31 35
9. M.M. Oken, R.H. Creech, and D.C. Tormey Toxicity and response criteria of the Eastern Cooperative Oncology Group Am J Clin Oncol 5 1982 649 655
10. R. Stupp, W.P. Mason, and M.J. van den Bent Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma N Engl J Med 352 2005 987 996
11. A.E. Sijben, J.B. McIntyre, and G.B. Roldan Toxicity from chemoradiotherapy in older patients with glioblastoma multiforme J Neurooncol 89 2008 97 103
12. M. Piccirilli, S. Bistazzoni, and F.M. Gagliardi Treatment of glioblastoma multiforme in elderly patients. Clinico-therapeutic remarks in 22 patients older than 80 years Tumori 92 2006 98 103
13. A.J. Chalmers, E.M. Ruff, and C. Martindale Cytotoxic effects of temozolomide and radiation are additive- and schedule-dependent Int J Radiat Oncol Biol Phys 75 2009 1511 1519
14. F. Keime-Guibert, O. Chinot, and L. Taillandier Radiotherapy for glioblastoma in the elderly N Engl J Med 356 2007 1527 1535
15. W. Roa, P.M. Brasher, and G. Bauman Abbreviated course of radiation therapy in older patients with glioblastoma multiforme: a prospective randomized clinical trial J Clin Oncol 22 2004 1583 1588