Pneumocystis molecular phylogeny: A way to understand both pneumocystosis natural history and host taxonomy

New Frontiers of Molecular Epidemiology of Infectious Diseases

Volumn 9789400721142, Issue , 2012, Pages 149-178

  Chabé, Magali ^a   Hugot, Jean Pierre ^b   Dei Cas, Eduardo ^a,c  

^a UNIV LILLE   (France)

^b MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^c LILLE UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84875498851     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-94-007-2114-2_8     Document Type: Chapter

References (190)

1. Aliouat EM, Dei-Cas E, Ouaissi A et al (1993a) In vitro attachment of Pneumocystis carinii from mouse and rat origin. Biol Cell 77:209-217
2. Aliouat EM, Mazars E, Dei-Cas E et al (1993b) Intranasal inoculation of mouse, rat or rabbitderived Pneumocystis in SCID mice. J Protozool Res 3:94-98
3. Aliouat EM, Mazars E, Dei-Cas E et al (1994) Pneumocystis cross infection experiments using SCID mice and nude rats as recipient host, showed strong host-species specificity. J Eukaryot Microbiol 41:S71
4. Aliouat EM, Escamilla R, Cariven C et al (1998) Surfactant changes during experimental pneumocystosis are related to the Pneumocystis development. Eur Respir J 11:542-547
5. Aliouat EM, Dujardin L, Martinez A et al (1999) Pneumocystis carinii growth kinetics in culture systems and in hosts: involvement of each life cycle parasite stage. J Eukaryot Microbiol 46:S116-S117
6. Aliouat-Denis CM, Chabé M, Demanche C et al (2008) Pneumocystis species, co-evolution and pathogenic power. Infect Genet Evol 8:708-726
7. Aliouat-Denis CM, Martinez A, Aliouat EM et al (2009) The Pneumocystis life cycle. Mem Inst Oswaldo Cruz 104:419-426
8. Allaert A, Levasseur P, Jouault T et al (1996) Role of alveolar macrophages during the spontaneous Pneumocystis carinii pneumonia of rabbits at weaning. J Eukaryot Microbiol 43:23S
9. Allaert A, Jouault T, Rajagopalan-Levasseur P et al (1997) Detection of cytokine mRNA in the lung during spontaneous Pneumocystis carinii pneumonia of the young rabbit. J Eukaryot Microbiol 44:45S
10. Banerji S, Lugli EB, Miller RF et al (1995) Analysis of genetic diversity at the arom locus in isolates of Pneumocystis carinii. J Eukaryot Microbiol 42:675-679
11. Barton EG, Campbell WG (1967) Further observations on the ultrastructure of Pneumocystis. Arch Pathol 83:527-534
12. Bauer NL, Paulsrud JR, Bartlett MS et al (1993) Pneumocystis carinii organisms obtained from rats, ferrets and mice are antigenically different. Infect Immun 61:1315-1319
13. Beard CB, Roux P, Nevez G et al (2004) Strain typing methods and molecular epidemiology of Pneumocystis pneumonia. Emerg Infect Dis 10:1729-1735
14. Beck JM, Preston AM, Wagner JG et al (1998) Interaction of rat Pneumocystis carinii and rat alveolar epithelial cells in vitro. Am J Physiol 275:L118-L125
15. Bishop R, Gurnell J, Laakkonen J et al (1997) Detection of Pneumocystis DNA in the lungs of several species of wild mammal. J Eukaryot Microbiol 44:57S
16. Blazec K (1960) Die Pneumocystis-pneumonia beim feldhasen (Lepus europeus Pallas, 1778). Zentralbl Allg Pathol Anat 101:484-489
17. Brooks DR, McLennan DA (1993) Parascript. In: Funk VA, Cannell PF (eds) Parasites and the language of evolution. Smithsonian Institution Press, Washington, DC, p 429
18. Burgess JW, Kottom TJ, Limper AH (2008) Pneumocystis carinii exhibits a conserved meiotic control pathway. Infect Immun 76:417-425
19. Cailliez JC, Séguy N, Denis CM et al (1996) Pneumocystis carinii: an atypical fungal microorganism. J Med Vet Mycol 34:227-239
20. Calderón EJ, Regordan C, Medrano FJ et al (1996) Pneumocystis carinii infection in patients with chronic bronchial disease. Lancet 347:977
21. Calderón EJ, Varela JM, Medrano FJ et al (2004) Epidemiology of Pneumocystis carinii pneumonia in southern Spain. Clin Microbiol Infect 10:673-676
22. Calderón EJ, Rivero L, Respaldiza N et al (2007) Systemic inflammation in patients with chronic obstructive pulmonary disease who are colonized with Pneumocystis jirovecii. Clin Infect Dis 45:17-19
23. Campbell WG (1972) Ultrastructure of Pneumocystis in human lungs: life cycle of human pneumocystosis. Arch Pathol 93:312-324
24. Cavallini Sanches EM, Pacheco SM, Cericatto AS et al (2009) Detection of Pneumocystis in lungs of bats from Brazil by PCR amplification. Pesqui Vet Bras 29:469-473
25. Ceré N, Drouet-Viard F, Dei-Cas E et al (1997) In utero transmission of Pneumocystis carinii sp. f. oryctolagi. Parasite 4:325-330
26. Chabé M, Dei-Cas E, Creusy C et al (2004) Immunocompetent hosts as a reservoir of Pneumocystis organisms: histological and RT-PCR data demonstrate active replication. Eur J Clin Microbiol Infect Dis 23:89-97
27. Chabé M, Nevez G, Totet A et al (2009) Transmission de Pneumocystis. J Mycol Med 19:276-284
28. Chabé M, Herbreteau V, Hugot JP et al (2010) Pneumocystis carinii and Pneumocystis wakefieldiae in wild Rattus norvegicus trapped in Thailand. J Eukaryot Microbiol 57:213-217
29. Chabé M, Aliouat-Denis CM, Delhaes L et al (2011) Pneumocystis: from a doubtful unique entity to a group of highly diversified fungal species. FEMS Yeast Res 11:2-17
30. Chagas C (1909) Nova tripanozomiazaea humana. Mem Inst Oswaldo Cruz 1:159-218
31. Christensen CBV, Settnes OP, Bille-Hansen V et al (1996) Pneumocystis carinii from pigs and humans are antigenically distinct. J Med Vet Mycol 34:431-433
32. Cornillot E, Keller B, Cushion MT et al (2002) Fine analysis of the Pneumocystis carinii f. sp. carinii genome by two-dimensional pulsed-field gel electrophoresis. Gene 293:87-95
33. Creusy C, Bahon-le Capon J, Fleurisse L et al (1996) Pneumocystis carinii pneumonia in four mammal species: histopathology and ultrastructure. J Eukaryot Microbiol 43:47S-48S
34. Cross JH, Hung CK (1975) Latent P. carinii infections in some mammals from Taipei Hsien, Taiwan. J Formos Med Assoc 74:564-567
35. Cushion MT (1998) Genetic heterogeneity of rat-derived Pneumocystis. FEMS Immunol Med Microbiol 22:51-58
36. Cushion MT (2004) Pneumocystis: unraveling the cloak of obscurity. Trends Microbiol 12:243-249
37. Cushion MT, Kaselis M, Stringer SL et al (1993) Genetic stability and diversity of Pneumocystis carinii infecting rat colonies. Infect Immun 61:4801-4813
38. Cushion M, Keely S, Stringer J (2004) Molecular and phenotypic description of Pneumocystis wakefieldiae sp.nov., a new species in rats. Mycologia 96:429-438
39. Cushion MT, Smulian AG, Slaven BE et al (2007) Transcriptome of Pneumocystis carinii during fulminate infection: carbohydrate metabolism and the concept of a compatible parasite. PLoS One 2:e423. doi:10.1371/journal.pone.0000423
40. Cushion MT, Linke MJ, Ashbaugh A et al (2010) Echinocandin treatment of Pneumocystis pneumonia in rodent models depletes cysts leaving trophic burdens that cannot transmit the infection. PLoS One 5:e8524
41. De Hoog GS, Guarro J, Gené J et al (eds) (2000) Atlas of clinical fungi, 2nd edn. Centraalbureau voor Schimmelcultures (CBS)/Universitat Rovira i Virgili, Utrecht/Reus
42. de Souza W, Benchimol M (2005) Basic biology of Pneumocystis carinii: a mini review. Mem Inst Oswaldo Cruz 100:903-908
43. De Stefano JA, Cushion MT, Sleught R et al (1990) Analysis of Pneumocystis carinii cyst wall. I. Evidence for an outer surface membrane. J Protozool 37:428-435
44. Dei-Cas E (2000) Pneumocystis Infections: the iceberg? Med Mycol 1:23-32
45. Dei-Cas E, Vernes A (1986) Parasitic adaptation of pathogenic fungi to the mammalian hosts. CRC Crit Rev Microbiol 13:173-218
46. Dei-Cas E, Jackson H, Palluault F et al (1991) Ultrastructural observations on the attachment of Pneumocystis carinii in vitro. J Protozool 38:S205-S207
47. Dei-Cas E, Cailliez JC, Palluault F et al (1992) Is Pneumocystis carinii a deep mycosis-like agent? Eur J Epidemiol 8:460-470
48. Dei-Cas E, Mazars E, Ödberg-Ferragut C et al (1994) Ultrastructural, genomic, isoenzymatic and biological features make it possible to distinguish rabbit Pneumocystis from other mammal Pneumocystis strains. J Eukaryot Microbiol 41:S84
49. Dei-Cas E, Mazars E, Aliouat EM et al (1998) The host-specificity of Pneumocystis carinii. J Mycol Med 8:1-6
50. Dei-Cas E, Aliouat EM, Cailliez JC (2004) Cellular structure. In: Walzer PD, Cushion MT (eds) Pneumocystis pneumonia, 3rd edn. Marcel Dekker Inc, New York, pp 61-94
51. Dei-Cas E, Chabé M, Moukhlis R et al (2006) Pneumocystis oryctolagi sp. nov., an uncultured fungus causing pneumonia in rabbits at weaning: review of current knowledge, and description of a new taxon on genotypic, phylogenetic and phenotypic bases. FEMS Microbiol Rev 80:853-871
52. Delanoë P, Delanoë E (1912) Sur les rapports des kystes de carinii du poumon des rats avec le Trypanosoma lewisi. CR Acad Sci 155:658-660
53. Demanche C, Berthelemy M, Petit T et al (2001) Phylogeny of Pneumocystis carinii from 18 primate species confirms host specificity and suggests coevolution. J Clin Microbiol 39:2126-2133
54. Demanche C, Petit T, Moisson P et al (2003) Assessment of Pneumocystis species carriage in captive primates. Vet Rec 152:811-813
55. Demanche C, Wanert F, Barthelemy M et al (2005) Molecular and serological evidence of Pneumocystis circulation in a social organization of healthy macaques (Macaca fascicularis). Microbiology 151:3117-3125
56. Denis CM, Mazars E, Guyot K et al (2000) Genetic divergence at the SOD-A locus of six different formae speciales of Pneumocystis carinii. Med Mycol 38:289-300
57. Derouiche S, Deville M, Taylor ML et al (2009) Pneumocystis diversity as a phylogeographic tool. Mem Inst Oswaldo Cruz 104:112-117
58. Doby JM, Kombila-Favry M (1978) Presence of sexual forms (cleistothecia and Hülle cells) in a case of human maxillary sinus aspergillosis caused by Aspergillus nidulans in association with Aspergillus fumigatus. Mycopathologia 64:157-163
59. Dumoulin A, Mazars E, Seguy N et al (2000) Transmission of Pneumocystis carinii disease from immunocompetent contacts of infected hosts to susceptible hosts. Eur J Clin Microbiol Infect Dis 19:671-678
60. Durand-Joly I, Wakefield AE, Palmer RJ et al (2000) Ultrastructural and molecular characterization of Pneumocystis carinii isolated from a rhesus monkey (Macaca mulatta). Med Mycol 38:61-72
61. Durand-Joly I, Aliouat EM, Recourt C et al (2002) Pneumocystis carinii f. sp. hominis is not infectious for SCID mice. J Clin Microbiol 40:1862-1865
62. Edman JC, Kovacs JA, Masur H et al (1988) Ribosomal RNA sequence shows Pneumocystis carinii to be a member of the fungi. Nature 334:519-522
63. Edman JC, Kovacs JA, Masur H et al (1989) Ribosomal RNA sequence shows Pneumocystis carinii to be a member of the fungi. J Protozool 36:S18-S20
64. English K, Peters SE, Maskell DJ et al (2001) DNA analysis of Pneumocystis infecting a Cavalier King Charles spaniel. J Eukaryot Microbiol 48:106S
65. Eriksson OE (1994) Pneumocystis carinii, a parasite in lungs of mammals, referred to a new family and order (Pneumocystidaceae, Pneumocystidales, Ascomycota). Systema Ascomycetum 13:165-180
66. Eriksson OE, Winka K (1997) Supraordinal taxa of the Ascomycota. Myconet 1:1-16
67. Esteves F, Gaspar J, Tavares A et al (2010) Population structure of Pneumocystis jirovecii isolated from immunodeficiency virus-positive patients. Infect Genet Evol 10:192-199
68. Fabre PH, Rodrigues A, Douzery EJP (2009) Patterns of macroevolution among primates inferred from a supermatrix of mitochondrial and nuclear DNA. Mol Phylogenet Evol 53:808-825
69. Fischer JM, Keely SP, Stringer JR (2006) Evolutionary rate of Ribosomal DNA in Pneumocystis species is normal despite the extraordinarily low copy-number of rDNA genes. J Eukaryot Microbiol 53:S156-S158
70. François F, Noël T, Pépin R et al (2001) Alternative identification test relying upon sexual reproductive abilities of Candida lusitaniae strains isolated from hospitalized patients. J Clin Microbiol 39:3906-3914
71. Fréalle E, Noël C, Viscogliosi E et al (2005) Manganese superoxide dismutase in pathogenic fungi: an issue with pathophysiological and phylogenetic involvements. FEMS Immunol Med Microbiol 45:411-422
72. Fréalle E, Noël C, Nolard N et al (2006) Manganese superoxide dismutase based phylogeny of pathogenic fungi. Mol Phylogenet Evol 41:28-39
73. Frenkel JK (1976) Pneumocystis jiroveci n. sp. from man: morphology, physiology, and immunology in relation to pathology. Natl Cancer Inst Monogr 43:13-30
74. Frenkel JK (1999) Pneumocystis pneumonia, an immunodeficiency-dependent disease (IDD): a critical historical overview. J Eukaryot Microbiol 46:S89-S92
75. Furuta T, Ueda K (1987) Intra-and interspecies transmission and antigenic difference of Pneumocystis carinii derived from rat and mouse. Jpn J Exp Med 57:11-17
76. Gigliotti F (1992) Host species-specific antigenic variation of a mannosylated surface glycoprotein of Pneumocystis carinii. J Infect Dis 165:329-336
77. Gigliotti F, Harmsen AG, Haidaris CG et al (1993) Pneumocystis carinii is not universally transmissible between mammalian species. Infect Immun 61:2886-2890
78. Gigliotti F, Harmsen AG, Wright TW (2003) Characterization of transmission of Pneumocystis carinii f.sp. muris through immunocompetent BALB/c mice. Infect Immun 71:3852-3856
79. Giuntoli D, Stringer SL, Stringer JR (1994) Extraordinarily low number of ribosomal RNA genes in P. carinii. J Eukaryot Microbiol 41:88S
80. Goyot P, Mojon M, Petavy AF (1986) Arvicola terrestris, Linnaeus 1758, a reservoir of Pneumocystis sp. Delanoë and Delanoë 1912.
81. Z Parasitenkd 72:685-687
82. Guarro J, Gené J, Stchigel AM (1999) Developments in fungal taxonomy. Clin Microbiol Rev 12:454-500
83. Guillot J, Chevalier V, Queney G et al (1999) Acquisition and biodiversity of Pneumocystis carinii in a colony of wild rabbits (Oryctolagus cuniculus). J Eukaryot Microbiol 46:100S-101S
84. Guillot J, Demanche C, Hugot JP et al (2001) Parallel phylogenies of Pneumocystis species and their mammalian hosts. J Eukaryot Microbiol 47:S113-S115
85. Haque AU, Plattner SB, Cook RT et al (1987) Pneumocystis carinii: taxonomy as viewed by electron microscopy. Am J Clin Pathol 87:504-510
86. Huang L, Friedly J, Morris AM et al (2001) Pneumocystis carinii dihydropteroate synthase genotypes in HIV-infected persons residing in San Francisco: possible implications for disease transmission. J Eukaryot Microbiol 48:137S-138S
87. Hugot JP (1999) Primates and their pinworm parasites: the Cameron hypothesis revisited. Syst Biol 48:523-546
88. Hugot JP, Demanche C, Barriel V et al (2003) Phylogenetic systematics and evolution of primatederived Pneumocystis based on mitochondrial or nuclear DNA sequence comparison. Syst Biol 52:735-744
89. Humphery-Smith I (1989) The evolution of phylogenetic specificity among parasitic organisms. Parasitol Today 5:385-387
90. Hunter JA, Wakefield AE (1996) Genetic divergence at the mitochondrial small subunit ribosomal RNA gene among isolates of Pneumocystis carinii from five mammalian host species. J Eukaryot Microbiol 43:S24-S25
91. Itatani CA (1994) Ultrastructural demonstration of a pore in the cyst wall of Pneumocystis carinii. J Parasitol 80:644-648
92. Itatani CA (1996) Ultrastructural morphology of intermediate forms and forms suggestive of conjugation in the life cycle of Pneumocystis carinii. J Parasitol 82:163-171
93. Ito M, Nozu R, Kuramochi T et al (2000) Prophylactic effect of FK463, a novel antifungal lipopeptide, against Pneumocystis carinii infection in mice. Antimicrob Agents Chemother 44:2259-2262
94. Kaneshiro ES, Collins MS, Cushion MT (2000) Inhibitors of sterol biosynthesis and amphotericin B reduce the viability of Pneumocystis carinii f.sp. carinii. Antimicrob Agents Chemother 44:1630-1638
95. Kazanjian P, Armstrong W, Hossler PA et al (2000) Pneumocystis carinii mutations are associated with duration of sulfa or sulfone prophylaxis exposure in AIDS patients. J Infect Dis 182:551-557
96. Keely SP, Fischer JM, Stringer JR (2003) Evolution and speciation of Pneumocystis. J Eukaryot Microbiol 50:S624-S626
97. Keely SP, Fischer JM, Cushion MT et al (2004) Phylogenetic identification of Pneumocystis murina sp. nov., a new species in laboratory mice. Microbiology 150:1153-1165
98. Kirkbride CA (1992) Etiologic agents detected in a 10-year study of bovine abortions and stillbirths. J Vet Diagn Invest 4:175-180
99. Kondo H, Taguchi M, Abe N et al (1993) Pathological changes in epidemic porcine Pneumocystis carinii pneumonia. J Comp Pathol 108:261-268
100. Kottom TJ, Thomas CF Jr, Mubarak KK et al (2000) Pneumocystis carinii uses a functional cdc13 B-type cyclin complex during its life cycle. Am J Respir Cell Mol Biol 22:722-731
101. Kottom TJ, Köhler JR, Thomas CF et al (2003) Lung epithelial cells and extracellular matrix components induce expression of Pneumocystis carinii STE20, a gene complementing the mating and pseudohyphal growth defects of STE20 mutant yeast. Infect Immun 71:6463-6471
102. Laakkonen J (1998) Pneumocystis carinii in wildlife. Int J Parasitol 28:241-252
103. Laakkonen J, Sukura A (1997) Pneumocystis carinii of the common shrew, Sorex araneus, shows a discrete phenotype. J Eukaryot Microbiol 44:117-121
104. Laakkonen J, Sukura A, Haukisalmi V et al (1993) Pneumocystis carinii and helminth parasitism in shrews Sorex araneus and Sorex caecutiens. J Wildl Dis 29:273-277
105. Laakkonen J, Fisher RN, Case TJ (2001) Pneumocystosis in wild small mammals from California. J Wildl Dis 37:408-412
106. Laakkonen J, Nyyssönen T, Hiltunen M et al (2006) Effects of Protostrongylus sp. And Pneumocystis sp. on the pulmonary tissue and the condition of mountain and brown hares from Finland. J Wildl Dis 42:780-787
107. Lainson R, Shaw JJ (1975) Pneumocystis and Histoplasma infections in wild animals from the Amazon region of Brazil. Trans R Soc Trop Med Hyg 69:505-508
108. Li Z, Feng X, Lu S et al (2008) Molecular phylogeny of Pneumocystis based on 5.8S rRNA gene and the internal transcribed spacers of rRNA gene sequences. Sci China C Life Sci 51: 445-452
109. Linke MJ, Cushion MT, Walzer PD (1989) Properties of the major antigens of rat and human Pneumocystis carinii. Infect Immun 57:1547-1555
110. Liu Y, Leigh JW, Brinkmann H et al (2009) Phylogenomic analyses support the monophyly of Taphrinomycotina, including Schizosaccharomyces fission yeasts. Mol Biol Evol 26:27-34
111. Lobetti RG, Leisewitz AL, Spencer JA (1996) Pneumocystis carinii in the miniature dachshund: case report and literature review. J Small Anim Pract 37:280-285
112. Ma L, Imamichi H, Sukura A et al (2001) Genetic divergence of the dihydrofolate reductase and dihydropteroate synthase genes in Pneumocystis carinii from 7 different host species. J Infect Dis 184:1485-1488
113. Matsumoto Y, Yoshida Y (1984) Sporogony in Pneumocystis carinii: synaptonemal complexes and meiotic nuclear divisions observed in precysts. J Protozool 31:420-428
114. Mazars E, Dei-Cas E (1998) Epidemiological and taxonomic impact of Pneumocystis biodiversity. FEMS Immunol Med Microbiol 22:75-80
115. Mazars E, Ödberg-Ferragut C, Durand I et al (1994) Genomic and isoenzymatic markers of Pneumocystis from different host species. J Eukaryot Microbiol 41:S104
116. Mazars E, Ödberg-Ferragut C, Dei-Cas E et al (1995) Polymorphism of Pneumocystis carinii from different host species. J Eukaryot Microbiol 42:26-32
117. Mazars E, Guyot K, Fourmaintraux S et al (1997a) Detection of Pneumocystis in European wild Animals. J Eukaryot Microbiol 44:39S
118. Mazars E, Guyot K, Durand I et al (1997b) Isoenzyme diversity in Pneumocystis carinii from rats, mice and rabbits. J Infect Dis 175:655-660
119. Mc Connell EE, Basson PA, Pienaar JG (1971) Pneumocystosis in a domestic goat. Onderstepoort J Vet Res 38:117-124
120. Mitchell RG, Chaplin AJ, Mackenzie DW (1987) Emericella nidulans in a maxillary sinus fungal mass. J Med Vet Mycol 25:339-341
121. Montes-Cano MA, Chabé M, Fontillon-Alberdi M et al (2009) Vertical transmission of Pneumocystis jirovecii in humans. Emerg Infect Dis 15:125-127
122. Nahimana A, Cushion MT, Blanc DS et al (2001) Rapid PCR-single-strand conformation polymorphism method to differentiate and estimate relative abundance of Pneumocystis carinii special forms infecting rats. J Clin Microbiol 39:4563-4565
123. Nevez G, Chabé M, Rabodonirina M et al (2008) Nosocomial Pneumocystis jirovecii infections. Parasite 15:359-365
124. Nielsen MH, Settnes OP, Aliouat EM et al (1998) Different ultrastructural morphology of Pneumocystis carinii derived from mice, rats, and rabbits. APMIS 106:771-779
125. Nishida H, Sugiyama J (1993) Phylogenetic relationships among Taphrina, Saitoella, and other higher fungi. Mol Biol Evol 10:431-436
126. O'Connell RJ, Panstruga R (2006) Tête à tête inside a plant cell: establishing compatibility between plants and biotrophic fungi and oomycetes. New Phytol 4:699-718
127. O'Connor BM (1985) Host associations and coevolutionary relationships of astigmatid mite parasites of new world primates. I. Families Psoroptidae and Audycoptidae. Fieldiana, Zoology (new series) 39:245-260
128. Ortiz-Rivera M, Liu Y, Felder R et al (1995) Comparison of coding and spacer region sequences of chromosomal rRNA-coding genes of two sequevars of Pneumocystis carinii. J Eukaryot Microbiol 42:44-49
129. Page RDM (1995) Parallel phylogenies: reconstructing the history of host-parasite assemblages. Cladistics 10:155-173
130. Palluault F, Slomianny C, Soulez B et al (1992) High osmotic pressure enables fine ultrastructural and cytochemical studies on Pneumocystis carinii. I: Epon embedding. Parasitol Res 78:437-444
131. Palmer RJ, Cushion MT, Wakefield AE (1999) Discrimination of rat-derived Pneumocystis carinii f. sp. carinii and Pneumocystis carinii f. sp. ratti using the polymerase chain reaction. Mol Cell Probes 13:147-155
132. Palmer RJ, Settnes OP, Lodal J et al (2000) Population structure of rat-derived Pneumocystis carinii in Danish wild rats. Appl Environ Microbiol 66:4954-4961
133. Perron Lepage MF, Gerber V, Suter MM (1999) A case of interstitial pneumonia associated with Pneumocystis carinii in a foal. Vet Pathol 36:621-624
134. Peters SE, English K, Laakkonen J et al (1994a) DNA analysis of Pneumocystis carinii infecting Finnish and English shrews. J Eukaryot Microbiol 41:108S
135. Peters SE, Wakefield AE, Whitwell KE et al (1994b) Pneumocystis carinii pneumonia in thoroughbred foals: identification of a genetically distinct organism by DNA amplification. J Clin Microbiol 32:213-216
136. Peters SE, English K, Rana A et al (2001) Synaptonemal complexes in the pre-cyst of Pneumocystis carinii. J Eukaryot Microbiol 48:S134
137. Peterson JC, Cushion MT (2005) Pneumocystis: not just pneumonia. Curr Opin Microbiol 8:393-398
138. Poelma FG (1975) Pneumocystis carinii in zoo animals. Parasitenkd 46:61
139. Powles MA, Liberator P, Anderson J et al (1998) Efficacy of MK-991 (L-743,872), a semisynthetic pneumocandin, in murine models of Pneumocystis carinii. Antimicrob Agents Chemother 42:1985-1989
140. Prévost MC, Aliouat EM, Escamilla R et al (1997) Pneumocystosis in humans or in corticosteroiduntreated animal models: interactions between pulmonary surfactant changes and Pneumocystis carinii in vivo or in vitro growth. J Eukaryot Microbiol 44:58S
141. Rajagopalan-Levasseur P, Allaert A, Dridba M et al (1998) Response to Pneumocystis infection in an immunocompetent host. FEMS Immunol Med Microbiol 22:107-121
142. Reed C, O'Donoghue JL (1979) A new guinea pig mutant with abnormal hair production and immunodeficiency. Lab Anim Sci 29:744-748
143. Reed DL, Smith VS, Hammond SL et al (2004) Genetic analysis of lice supports direct contact between modern and archaic humans. PLoS Biol 2:e340
144. Rivero L, de la Horra C, Montes-Cano MA et al (2008) Pneumocystis jirovecii transmission from immunocompetent carriers to infant. Emerg Infect Dis 14:1116-1118
145. Sanches EM, Pescador C, Rozza D et al (2007) Detection of Pneumocystis spp. in lung samples from pigs in Brazil. Med Mycol 45:395-399
146. Sanchez CA, Chabé M, Aliouat EM et al (2007) Exploring transplacental transmission of Pneumocystis oryctolagi in first-time pregnant and multiparous rabbit does. Med Mycol 45:701-707
147. Schaffzin JK, Stringer JR (2000) The major surface glycoprotein expression sites of two special forms of rat Pneumocystis carinii differ in structure. J Infect Dis 181:1729-1739
148. Settnes OP, Hasselager E (1984) Occurrence of Pneumocystis carinii Delanoë & Delanoë, 1912 in dogs and cats in Denmark. Nord Vet Med 36:179-181
149. Settnes OP, Henriksen SA (1989) Pneumocystis carinii in large domestic animals in Denmark. A preliminary report. Acta Vet Scand 30:437-440
150. Settnes OP, Lodal J (1980) Prevalence of Pneumocystis carinii Delanoë & Delanoë, 1912 in rodents in Denmark. Nord Vet Med 32:17-27
151. Settnes OP, Nielsen MJ (1991) Host-parasite relationship in Pneumocystis carinii infection: activation of the plasmalemmal vesicular system in type I alveolar epithelial cells. J Protozool 38:S174-S176
152. Settnes OP, Elvestad K, Clausen B (1986) Pneumocystis carinii Delanoë & Delanoë, 1912 found in lungs of freeliving animals in Denmark at autopsy. Nord Vet Med 38:11-15
153. Settnes OP, Bille-Hansen V, Jorsal SE, Henriksen SA (1991) The piglet as a potential model of Pneumocystis carinii pneumonia. J Protozool 38:140S-141S
154. Settnes OP, Nielsen PB, Bucala R et al (1994) A survey of birds in Denmark for the presence of Pneumocystis carinii. Avian Dis 38:1-10
155. Sexton AC, Howlett BJ (2006) Parallels in fungal pathogenesis on plant and animal hosts. Eukaryot Cell 5:1941-1949
156. Shimizu A, Kimura F, Kimura S (1985) Occurrence of Pneumocystis carinii in animals in Japan. Nippon Juigaku Zasshi 47:309-311
157. Shiota T, Shimada Y, Kurimoto H, Oikawa H (1990) Pneumocystis carinii infection in corticosteroidtreated cats. J Parasitol 76:441-445
158. Siddall ME (1997) The AIDS pandemic is new, but is HIV not new? Cladistics 13:267-274
159. Sinclair K, Wakefield AE, Banerji S et al (1991) Pneumocystis carinii organisms derived from rat and human hosts are genetically distinct. Mol Biochem Parasitol 45:183-184
160. Smulian AG, Sesterhenn T, Tanaka R et al (2001) The ste3 pheromone receptor gene of Pneumocystis carinii is surrounded by a cluster of signal transduction genes. Genetics 157:991-1002
161. Soulez B, Dei-Cas E, Charet P et al (1989) The young rabbit: a nonimmunosuppressed model for Pneumocystis carinii pneumonia. J Infect Dis 160:355-356
162. Stedman TT, Butler DR, Buck GA (1998) The HSP70 gene family in Pneumocystis carinii: molecular and phylogenetic characterization of cytoplasmic members. J Eukaryot Microbiol 45:589-599
163. Stringer JR, Stringer SL, Zhang J (1993) Molecular genetic distinction of Pneumocystis carinii from rats and humans. J Eukaryot Microbiol 40:733-741
164. Stringer JR, Cushion MT, Wakefield AE (2001) New nomenclature for the genus Pneumocystis. J Eukaryot Microbiol 48:184-189
165. Sukura A, Saari S, Järvinen AK, Olsson M, Kärkkäinen M, Ilvesniemi T (1996) Pneumocystis carinii pneumonia in dogs-a diagnostic challenge. J Vet Diagn Invest 8:124-130
166. Tamburrini E, Ortona E, Visconti E et al (1999) Pneumocystis carinii infection in young nonimmunosuppressed rabbits. Kinetics of infection and of the primary specific immune response. Med Microbiol Immunol 188:1-7
167. Tang X, Bartlett MS, Smith JW et al (1998) Determination of copy number of rRNA genes in Pneumocystis carinii f. sp. hominis. J Clin Microbiol 36:2491-2494
168. Taylor JW, Jacobson DJ, Kroken S et al (2000) Phylogenetic species recognition and species concepts in fungi. Fungal Genet Biol 31:21-32
169. Thomas CF Jr, Limper AH (2007) Current insights into the biology and pathogenesis of Pneumocystis pneumonia. Nat Rev Microbiol 5:298-308
170. Thomas CF, Anders RA, Gustafson MP et al (1998) Pneumocystis carinii contains a functional cell-division-cycle Cdc2 homologue. Am J Respir Cell Mol Biol 18:297-306
171. Totet A, Latouche S, Lacube P et al (2004) Pneumocystis jirovecii dihydropteroate synthase genotypes in immunocompetent infants and immunosuppressed adults, Amiens, France. Emerg Infect Dis 10:667-673
172. Utili R, Durante-Mangoni E, Basilico C et al (2007) Efficacy of caspofungin addition to trimethoprimsulfamethoxazole treatment for severe Pneumocystis pneumonia in solid organ transplant recipients. Transplantation 84:685-688
173. Vargas SL, Ponce CA, Gigliotti F et al (2000) Transmission of Pneumocystis carinii DNA from a patient with P. carinii pneumonia to immunocompetent contact health care workers. J Clin Microbiol 38:1536-1538
174. Vasquez J, Smulian AG, Linke MJ et al (1996) Antigenic differences associated with genetically distinct Pneumocystis carinii from rats. Infect Immun 64:290-297
175. Vavra J, Kucera K (1970) Pneumocystis carinii Delanoë, its ultrastructure and ultrastructural affinities. J Protozool 17:463-483
176. Villegas LR, Kottom TJ, Limper AH (2009) Characterization of PCEng2 a {beta}-1,3-endoglucanase homologue in Pneumocystis carinii with activity in cell wall regulation. Am J Respir Cell Mol Biol 43(2):192-200
177. Vohra PK, Puri V, Thomas CF Jr (2003a) Complementation and characterization of the Pneumocystis carinii MAPK, PCM. FEBS Lett 551:139-146
178. Vohra PK, Puri V, Kottom TJ et al (2003b) Pneumocystis carinii STE11, an HMG-box protein, is phosphorylated by the mitogen activated protein kinase PCM. Gene 312:173-179
179. Vohra PK, Park JG, Sanyal B et al (2004) Expression analysis of PCSTE3, a putative pheromone receptor from the lung pathogenic fungus Pneumocystis carinii. Biochem Biophys Res Commun 319:193-199
180. Wakefield AE (1998) Genetic heterogeneity in Pneumocystis carinii: an introduction. FEMS Immunol Med Microbiol 22:97-101
181. Wakefield AE (2002) Pneumocystis carinii. Br Med Bull 61:175-188
182. Wakefield AE, Peters SE, Banerji S et al (1992) Pneumocystis carinii shows DNA homology with the ustomycetous red yeast fungi. Mol Microbiol 6:1903-1911
183. Wakefield AE, Keely SP, Stringer JR et al (1997) Identification of porcine Pneumocystis carinii as a genetically distinct organism by DNA amplification. APMIS 105:317-321
184. Weinberg GA, Bartlett MS (1991) Comparison of pulsed field gel electrophoresis karyotypes of Pneumocystis carinii derived from rat lung, cell culture and ferret lung. J Protozool 38:64-65
185. Wilson DE, Bartsch RC, Bigalke RD et al (1974) Observations on mortality rates and disease in roan and sable antelope on nature reserves in the Transvaal. J S Afr Wildl Manage Assoc 4:203-206
186. Wyder MA, Rasch EM, Kaneshiro ES (1998) Quantitation of absolute Pneumocystis carinii nuclear DNA content. Trophic and cystic forms isolated from infected rat lungs are haploid organisms. J Eukaryot Microbiol 45:233-239
187. Yonushonis WP, Elwell MR, Lawyer PG et al (1986) Infection of a three-toed sloth (Bradypus variegatus) by a Pneumocystis-like organism in Panama. Wildl Dis 22:572-575
188. Yoshida Y (1989) Ultrastructural studies of Pneumocystis carinii. J Protozool 36:53-60
189. Yoshida Y, Yamada M, Shiota T et al (1981) Provocation experiment: Pneumocystis carinii in several kinds of animals. Zentralbl Bakteriol Mikrobiol Hyg A 250:206-212
190. Yoshida Y, Matsumoto Y, Yamada M et al (1984) Pneumocystis carinii: electron microscopic investigation on the interaction of trophozoite and alveolar lining cell. Zentralbl Bakteriol Mikrobiol Hyg A 256:390-399