Attenuated Escherichia coli strains expressing the colonization factor antigen I (CFA/I) and a detoxified heat-labile enterotoxin (LThK63) enhance clearance of ETEC from the lungs of mice and protect mice from intestinal ETEC colonization and LT-induced fluid accumulation

Veterinary Immunology and Immunopathology

Volumn 152, Issue 1-2, 2013, Pages 57-67

  Byrd, Wyatt ^a,b   Boedeker, Edgar C ^a,b  

^a NEW MEXICO VA HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

CFA I; ETEC; Intragastric; Intranasal; LThK63

Indexed keywords

BACTERIAL ANTIGEN; COLONIZATION FACTOR ANTIGEN I; ESCHERICHIA COLI ENTEROTOXIN; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; UNCLASSIFIED DRUG; VACCINE;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN EXPRESSION; ARTICLE; ATTENUATION; BACTERIAL COLONIZATION; CONTROLLED STUDY; ENTEROTOXIGENIC ESCHERICHIA COLI; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOGLOBULIN BLOOD LEVEL; IN VIVO STUDY; LUNG LAVAGE; MOUSE; NONHUMAN; WILD TYPE;

ANIMALS; BACTERIAL TOXINS; ENTEROTOXIGENIC ESCHERICHIA COLI; ENTEROTOXINS; ESCHERICHIA COLI INFECTIONS; ESCHERICHIA COLI PROTEINS; ESCHERICHIA COLI VACCINES; FECES; FEMALE; FIMBRIAE PROTEINS; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INTESTINES; LUNG; MICE; MICE, INBRED BALB C; RANDOM ALLOCATION; VACCINES, ATTENUATED;

ESCHERICHIA COLI; MUS;

EID: 84875498461     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2012.10.001     Document Type: Article

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