-
1
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
Dang L., White D.W., Gross S., Bennett B.D., Bittinger M.A., Driggers E.M., Fantin V.R., Jang H.G., Jin S., Keenan M.C., Marks K.M., Prins R.M., Ward P.S., Yen K.E., Liau L.M., Rabinowitz J.D., Cantley L.C., Thompson C.B., Vander Heiden M.G., Su S.M. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 2009, 462:739-744.
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
Bennett, B.D.4
Bittinger, M.A.5
Driggers, E.M.6
Fantin, V.R.7
Jang, H.G.8
Jin, S.9
Keenan, M.C.10
Marks, K.M.11
Prins, R.M.12
Ward, P.S.13
Yen, K.E.14
Liau, L.M.15
Rabinowitz, J.D.16
Cantley, L.C.17
Thompson, C.B.18
Vander Heiden, M.G.19
Su, S.M.20
more..
-
2
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan H., Parsons D.W., Jin G., McLendon R., Rasheed B.A., Yuan W., Kos I., Batinic-Haberle I., Jones S., Riggins G.J., Friedman H., Friedman A., Reardon D., Herndon J., Kinzler K.W., Velculescu V.E., Vogelstein B., Bigner D.D. IDH1 and IDH2 mutations in gliomas. N. Engl. J. Med. 2009, 360:765-773.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
McLendon, R.4
Rasheed, B.A.5
Yuan, W.6
Kos, I.7
Batinic-Haberle, I.8
Jones, S.9
Riggins, G.J.10
Friedman, H.11
Friedman, A.12
Reardon, D.13
Herndon, J.14
Kinzler, K.W.15
Velculescu, V.E.16
Vogelstein, B.17
Bigner, D.D.18
-
3
-
-
82255183048
-
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome
-
Pansuriya T.C., van Eijk R., d'Adamo P., van Ruler M.A., Kuijjer M.L., Oosting J., Cleton-Jansen A.M., van Oosterwijk J.G., Verbeke S.L., Meijer D., van Wezel T., Nord K.H., Sangiorgi L., Toker B., Liegl-Atzwanger B., San-Julian M., Sciot R., Limaye N., Kindblom L.G., Daugaard S., Godfraind C., Boon L.M., Vikkula M., Kurek K.C., Szuhai K., French P.J., Bovee J.V. Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome. Nat. Genet. 2011, 43:1256-1261.
-
(2011)
Nat. Genet.
, vol.43
, pp. 1256-1261
-
-
Pansuriya, T.C.1
van Eijk, R.2
dAdamo, P.3
van Ruler, M.A.4
Kuijjer, M.L.5
Oosting, J.6
Cleton-Jansen, A.M.7
van Oosterwijk, J.G.8
Verbeke, S.L.9
Meijer, D.10
van Wezel, T.11
Nord, K.H.12
Sangiorgi, L.13
Toker, B.14
Liegl-Atzwanger, B.15
San-Julian, M.16
Sciot, R.17
Limaye, N.18
Kindblom, L.G.19
Daugaard, S.20
Godfraind, C.21
Boon, L.M.22
Vikkula, M.23
Kurek, K.C.24
Szuhai, K.25
French, P.J.26
Bovee, J.V.27
more..
-
4
-
-
82255183051
-
Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2
-
Amary M.F., Damato S., Halai D., Eskandarpour M., Berisha F., Bonar F., McCarthy S., Fantin V.R., Straley K.S., Lobo S., Aston W., Green C.L., Gale R.E., Tirabosco R., Futreal A., Campbell P., Presneau N., Flanagan A.M. Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2. Nat. Genet. 2011, 43:1262-1265.
-
(2011)
Nat. Genet.
, vol.43
, pp. 1262-1265
-
-
Amary, M.F.1
Damato, S.2
Halai, D.3
Eskandarpour, M.4
Berisha, F.5
Bonar, F.6
McCarthy, S.7
Fantin, V.R.8
Straley, K.S.9
Lobo, S.10
Aston, W.11
Green, C.L.12
Gale, R.E.13
Tirabosco, R.14
Futreal, A.15
Campbell, P.16
Presneau, N.17
Flanagan, A.M.18
-
5
-
-
77649305610
-
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
-
Ward P.S., Patel J., Wise D.R., Abdel-Wahab O., Bennett B.D., Coller H.A., Cross J.R., Fantin V.R., Hedvat C.V., Perl A.E., Rabinowitz J.D., Carroll M., Su S.M., Sharp K.A., Levine R.L., Thompson C.B. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell 2010, 17:225-234.
-
(2010)
Cancer Cell
, vol.17
, pp. 225-234
-
-
Ward, P.S.1
Patel, J.2
Wise, D.R.3
Abdel-Wahab, O.4
Bennett, B.D.5
Coller, H.A.6
Cross, J.R.7
Fantin, V.R.8
Hedvat, C.V.9
Perl, A.E.10
Rabinowitz, J.D.11
Carroll, M.12
Su, S.M.13
Sharp, K.A.14
Levine, R.L.15
Thompson, C.B.16
-
6
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons D.W., Jones S., Zhang X., Lin J.C., Leary R.J., Angenendt P., Mankoo P., Carter H., Siu I.M., Gallia G.L., Olivi A., McLendon R., Rasheed B.A., Keir S., Nikolskaya T., Nikolsky Y., Busam D.A., Tekleab H., Diaz L.A., Hartigan J., Smith D.R., Strausberg R.L., Marie S.K., Shinjo S.M., Yan H., Riggins G.J., Bigner D.D., Karchin R., Papadopoulos N., Parmigiani G., Vogelstein B., Velculescu V.E., Kinzler K.W. An integrated genomic analysis of human glioblastoma multiforme. Science 2008, 321:1807-1812.
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
Mankoo, P.7
Carter, H.8
Siu, I.M.9
Gallia, G.L.10
Olivi, A.11
McLendon, R.12
Rasheed, B.A.13
Keir, S.14
Nikolskaya, T.15
Nikolsky, Y.16
Busam, D.A.17
Tekleab, H.18
Diaz, L.A.19
Hartigan, J.20
Smith, D.R.21
Strausberg, R.L.22
Marie, S.K.23
Shinjo, S.M.24
Yan, H.25
Riggins, G.J.26
Bigner, D.D.27
Karchin, R.28
Papadopoulos, N.29
Parmigiani, G.30
Vogelstein, B.31
Velculescu, V.E.32
Kinzler, K.W.33
more..
-
7
-
-
70349594347
-
Analysis of IDH1 and IDH2 mutations in Japanese glioma patients
-
Sonoda Y., Kumabe T., Nakamura T., Saito R., Kanamori M., Yamashita Y., Suzuki H., Tominaga T. Analysis of IDH1 and IDH2 mutations in Japanese glioma patients. Cancer sci. 2009, 100:1996-1998.
-
(2009)
Cancer sci.
, vol.100
, pp. 1996-1998
-
-
Sonoda, Y.1
Kumabe, T.2
Nakamura, T.3
Saito, R.4
Kanamori, M.5
Yamashita, Y.6
Suzuki, H.7
Tominaga, T.8
-
8
-
-
56749156414
-
Analysis of the IDH1 codon 132 mutation in brain tumors
-
Balss J., Meyer J., Mueller W., Korshunov A., Hartmann C., von Deimling A. Analysis of the IDH1 codon 132 mutation in brain tumors. Acta Neuropathol. 2008, 116:597-602.
-
(2008)
Acta Neuropathol.
, vol.116
, pp. 597-602
-
-
Balss, J.1
Meyer, J.2
Mueller, W.3
Korshunov, A.4
Hartmann, C.5
von Deimling, A.6
-
9
-
-
69949114447
-
Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1010 diffuse gliomas
-
Hartmann C., Meyer J., Balss J., Capper D., Mueller W., Christians A., Felsberg J., Wolter M., Mawrin C., Wick W., Weller M., Herold-Mende C., Unterberg A., Jeuken J.W., Wesseling P., Reifenberger G., von Deimling A. Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1010 diffuse gliomas. Acta Neuropathol. 2009, 118:469-474.
-
(2009)
Acta Neuropathol.
, vol.118
, pp. 469-474
-
-
Hartmann, C.1
Meyer, J.2
Balss, J.3
Capper, D.4
Mueller, W.5
Christians, A.6
Felsberg, J.7
Wolter, M.8
Mawrin, C.9
Wick, W.10
Weller, M.11
Herold-Mende, C.12
Unterberg, A.13
Jeuken, J.W.14
Wesseling, P.15
Reifenberger, G.16
von Deimling, A.17
-
10
-
-
78650018623
-
The next generation of glioma biomarkers: MGMT methylation, BRAF fusions and IDH1 mutations
-
von Deimling A., Korshunov A., Hartmann C. The next generation of glioma biomarkers: MGMT methylation, BRAF fusions and IDH1 mutations. Brain Pathol. 2011, 21:74-87.
-
(2011)
Brain Pathol.
, vol.21
, pp. 74-87
-
-
von Deimling, A.1
Korshunov, A.2
Hartmann, C.3
-
11
-
-
70449518400
-
Monoclonal antibody specific for IDH1 R132H mutation
-
Capper D., Zentgraf H., Balss J., Hartmann C., von Deimling A. Monoclonal antibody specific for IDH1 R132H mutation. Acta Neuropathol. 2009, 118:599-601.
-
(2009)
Acta Neuropathol.
, vol.118
, pp. 599-601
-
-
Capper, D.1
Zentgraf, H.2
Balss, J.3
Hartmann, C.4
von Deimling, A.5
-
12
-
-
70449708940
-
A monoclonal antibody IMab-1 specifically recognizes IDH1R132H, the most common glioma-derived mutation
-
Kato Y., Jin G., Kuan C.T., McLendon R.E., Yan H., Bigner D.D. A monoclonal antibody IMab-1 specifically recognizes IDH1R132H, the most common glioma-derived mutation. Biochem. Biophys. Res. Commun. 2009, 390:547-551.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.390
, pp. 547-551
-
-
Kato, Y.1
Jin, G.2
Kuan, C.T.3
McLendon, R.E.4
Yan, H.5
Bigner, D.D.6
-
13
-
-
79953024539
-
Establishment of a novel monoclonal antibody SMab-1 specific for IDH1-R132S mutation
-
Kaneko M.K., Tian W., Takano S., Suzuki H., Sawa Y., Hozumi Y., Goto K., Yamazaki K., Kitanaka C., Kato Y. Establishment of a novel monoclonal antibody SMab-1 specific for IDH1-R132S mutation. Biochem. Biophys. Res. Commun. 2011, 406:608-613.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.406
, pp. 608-613
-
-
Kaneko, M.K.1
Tian, W.2
Takano, S.3
Suzuki, H.4
Sawa, Y.5
Hozumi, Y.6
Goto, K.7
Yamazaki, K.8
Kitanaka, C.9
Kato, Y.10
-
14
-
-
84864030931
-
Immunohistochemical detection of IDH1 mutation, p53, and internexin as prognostic factors of glial tumors
-
Takano S., Kato Y., Yamamoto T., Kaneko M.K., Ishikawa E., Tsujimoto Y., Matsuda M., Nakai K., Yanagiya R., Morita S., Tsuboi K., Matsumura A. Immunohistochemical detection of IDH1 mutation, p53, and internexin as prognostic factors of glial tumors. J. Neurooncol. 2012, 108:361-373.
-
(2012)
J. Neurooncol.
, vol.108
, pp. 361-373
-
-
Takano, S.1
Kato, Y.2
Yamamoto, T.3
Kaneko, M.K.4
Ishikawa, E.5
Tsujimoto, Y.6
Matsuda, M.7
Nakai, K.8
Yanagiya, R.9
Morita, S.10
Tsuboi, K.11
Matsumura, A.12
-
15
-
-
84875368172
-
Establishment of novel monoclonal antibodies KMab-1 and MMab-1 specific for IDH2 mutations
-
Kaneko M., Morita S., Tsujimoto Y., Yanagiya R., Nasu K., Sasaki H., Hozumi Y., Goto K., Natsume A., Watanabe M., Kumabe T., Takano S., Kato Y. Establishment of novel monoclonal antibodies KMab-1 and MMab-1 specific for IDH2 mutations. Biochem. Biophys. Res. Commun. 2013, 432:40-45.
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.432
, pp. 40-45
-
-
Kaneko, M.1
Morita, S.2
Tsujimoto, Y.3
Yanagiya, R.4
Nasu, K.5
Sasaki, H.6
Hozumi, Y.7
Goto, K.8
Natsume, A.9
Watanabe, M.10
Kumabe, T.11
Takano, S.12
Kato, Y.13
-
16
-
-
84876498207
-
Generation of a novel monoclonal antibody WMab-1 specific for IDH2-R172W mutation
-
in press.
-
Y. Kato, M.K. Kaneko, Generation of a novel monoclonal antibody WMab-1 specific for IDH2-R172W mutation, Biochem. Biophys. Res. Commun. (2013), in press.
-
(2013)
Biochem. Biophys. Res. Commun.
-
-
Kato, Y.1
Kaneko, M.K.2
|