Temporal properties of fear extinction - Does time matter?

Behavioral Neuroscience

Volumn 127, Issue 1, 2013, Pages 59-69

  Golkar, Armita ^a   Bellander, Martin ^a   öhman, Arne ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Associative learning; Exposure; Extinction; Fear conditioning

Indexed keywords

ADULT; ARTICLE; CONDITIONED REFLEX; CONDITIONING; FEAR; HUMAN; HUMAN EXPERIMENT; LONG TERM EXPOSURE; MALE; NORMAL HUMAN; PREDICTION; REINFORCEMENT; STARTLE REFLEX; STATE DEPENDENT LEARNING; TASK PERFORMANCE; TIME;

ADOLESCENT; ADULT; ASSOCIATION LEARNING; CONDITIONING, CLASSICAL; ELECTROMYOGRAPHY; EXTINCTION, PSYCHOLOGICAL; FEAR; FEMALE; HUMANS; MALE; PHOTIC STIMULATION; REINFORCEMENT (PSYCHOLOGY); STARTLE REACTION; TIME FACTORS;

EID: 84875489473     PISSN: 07357044     EISSN: 19390084     Source Type: Journal    
DOI: 10.1037/a0030892     Document Type: Article

References (37)

1. Barlow, D. H. (2002). Anxiety and its disorders: The nature and treatment of anxiety and panic (2nd ed.). New York, NY: Guilford Press.
2. Bouton, M. E. (1993). Context, time, and memory retrieval in the interference paradigms of Pavlovian learning. Psychological Bulletin, 114, 80-99.
3. Bouton, M. E., & Bolles, R. C. (1979a). Contextual control of the extinction of conditioned fear. Learning and Motivation, 10, 445-466.
4. Bouton, M. E., & Bolles, R. C. (1979b). Role of conditioned contextual stimuli in reinstatement of extinguished fear. Journal of Experimental Psychology: Animal Behavior Processes, 5, 368-378.
5. Bouton, M. E., & King, D. A. (1983). Contextual control of the extinction of conditioned fear - Test for the associative value of the context. Journal of Experimental Psychology: Animal Behavior Processes, 9, 248-265.
6. Brandon, S. E., Vogel, E. H., & Wagner, A. R., (2002). Computational theories of classical conditioning. In J. W. Moore (Ed.), A neuroscientist's guide to classical conditioning (pp. 232-310). New York, NY: Springer-Verlag.
7. Craske, M. G., Kircanski, K., Zelikowsky, M., Mystkowski, J., Chowdhury, N., & Baker, A. (2008). Optimizing inhibitory learning during exposure therapy. Behaviour Research and Therapy, 46, 5-27.
8. Davis, M., & Whalen, P. J. (2001). The amygdala: Vigilance and emotion. Molecular Psychiatry, 6, 13-34.
9. Drew, M. R., Yang, C., Ohyama, T., & Balsam, P. D. (2004). Temporal specificity of extinction in autoshaping. Journal of Experimental Psychology: Animal Behavior Processes, 30, 163-176.
10. Gallistel, C. R., & Gibbon, J. (2000). Time, rate, and conditioning. Psychological Review, 107, 289-344.
11. Golkar, A., & öhman, A. (2012). Fear extinction in humans: Effects of acquisition-extinction delay and masked stimulus presentations. Biological Psychology, 91, 292-301.
12. Golkar, A., Fürth, D., öhman, A., & Olsson, A. (2012). Extinction of conditioned fear to fear-relevant and fear-irrelevant stimuli. Manuscript in preparation.
13. Grillon, C., Ameli, R., Merikangas, K., Woods, S. W., & Davis, M. (1993). Measuring the time-course of anticipatory anxiety using the fear-potentiated startle reflex. Psychophysiology, 30, 340-346.
14. Grossberg, S., & Schmajuk, N. A. (1991). Neural dynamics of adaptive timing and temporal discrimination during associative learning. In S. Grossberg (Ed.), Pattern recognition by self-organizing neural networks (pp. 637-674). Cambridge, MA: MIT Press.
15. Haselgrove, M., & Pearce, J. M. (2003). Facilitation of extinction by an increase or a decrease in trial duration. Journal of Experimental Psychology: Animal Behavior Processes, 29, 153-166.
16. Kindt, M., Soeter, M., & Vervliet, B. (2009). Beyond extinction: Erasing human fear responses and preventing the return of fear. Nature Neuroscience, 12, 256-258.
17. LaBar, K. S., Gatenby, J. C., Gore, J. C., LeDoux, J. E., & Phelps, E. A. (1998). Human amygdala activation during conditioned fear acquisition and extinction: A mixed-trial fMRI study. Neuron, 20, 937-945.
18. Lang, P. J., Davis, M., & öhman, A. (2000). Fear and anxiety: Animal models and human cognitive psychophysiology. Journal of Affective Disorders, 61, 137-159.
19. LeDoux, J. E. (2000). Emotion circuits in the brain. Annual Review of Neuroscience, 23, 155-184.
20. Lundqvist, D., Flykt, A., & öhman, A. (1998). KDEF: The Karolinska Directed Emotional Faces [CD-ROM]. Stockholm, Sweden: Karolinska Institutet, Department of Clinical Neuroscience, Psychology Section.
21. Maren, S., & Quirk, G. J. (2004). Neuronal signalling of fear memory. Nature Reviews Neuroscience, 5, 844-852.
22. Norrholm, S. D., Jovanovic, T., Vervliet, B., Myers, K. M., Davis, M., Rothbaum, B. O., & Duncan, E. J. (2006). Conditioned fear extinction and reinstatement in a human fear-potentiated startle paradigm. Learning & Memory, 13, 681-685.
23. Norrholm, S. D., Vervliet, B., Jovanovic, T., Boshoven, W., Myers, K. M., Davis, M., . . . Duncan, E. J. (2008). Timing of extinction relative to acquisition: A Parametric analysis of fear extinction in humans. Behavioral Neuroscience, 122, 1016-1030.
24. öhman, A., Fredrikson, M., Hugdahl, K., & Rimmo, P. A. (1976). Premise of equipotentiality in human classical-conditioning: Conditioned electrodermal responses to potentially phobic stimuli. Journal of Experimental Psychology: General, 105, 313-337.
25. öhman, A., & Mineka, S. (2001). Fears, phobias, and preparedness: Toward an evolved module of fear and fear learning. Psychological Review, 108, 483-522.
26. Phelps, E. A., Delgado, M. R., Nearing, K. I., & LeDoux, J. E. (2004). Extinction learning in humans: Role of the amygdala and vmPFC. Neuron, 43, 897-905.
27. Plendl, W., & Wotjak, C. T. (2010). Dissociation of withinand between-session extinction of conditioned fear. The Journal of Neuroscience, 30, 4990-4998.
28. Prenoveau, J. M., Craske, M. G., Liao, B., & Ornitz, E. M. (2012). Human fear conditioning and extinction: Timing is everything . . . or is it? Biological Psychology. Advance online publication.
29. Quirk, G. J., & Gehlert, D. R. (2003). Inhibition of the amygdala: Key to pathological states? Annals of New York Academy of Sciences, 985, 263-272.
30. Rescorla, R. A. (2004). Spontaneous recovery. Learning & Memory, 11, 501-509.
31. Rescorla, R. A., & Heth, C. D. (1975). Reinstatement of fear to an extinguished conditioned stimulus. Journal of Experimental Psychology: Animal Behavior Processes, 1, 88-96.
32. Rescorla, R. A., & Wagner, A. R. (1972). A theory of Pavlovian conditioning: Variations in the effectiveness of reinforcement and nonreinforcement. In A. H. B. W. F. Prokasy (Ed.), Classical conditioning: II. Current research and theory (pp. 64-99). New York, NY: AppletonCentury-Crofts.
33. Shipley, R. H. (1974). Extinction of conditioned fear in rats as a function of several parameters of CS exposure. Journal of Comparative and Physiological Psychology, 87, 699-707.
34. Sotres-Bayon, F., Bush, D. E., LeDoux, J. E., Sotres-Bayon, F., Bush, D. E. A., & LeDoux, J. E. (2004). Emotional perseveration: An update on prefrontal-amygdala interactions in fear extinction. Learning & Memory, 11, 525-535.
35. Weike, A. I., Hamm, A. O., Schupp, H. T., Runge, U., Schroeder, H. W. S., & Kessler, C. (2005). Fear conditioning following unilateral temporal lobectomy: Dissociation of conditioned startle potentiation and autonomic learning. The Journal of Neuroscience, 25, 11117-11124.
36. Weike, A. I., Schupp, H. T., & Hamm, A. O. (2007). Fear acquisition requires awareness in trace but not delay conditioning. Psychophysiology, 44, 170-180.
37. Westbrook, R. F., Iordanova, M., McNally, G., Richardson, R., & Harris, J. A. (2002). Reinstatement of fear to an extinguished conditioned stimulus: Two roles for context. Journal of Experimental Psychology: Animal Behavior Processes, 28, 97-110.