Outbreak of carbapenem-resistant Klebsiella pneumoniae: Two-year epidemiologic follow-up in a tertiary hospital

Memorias do Instituto Oswaldo Cruz

Volumn 108, Issue 1, 2013, Pages 113-115

  Hanna Pereira, Graziella ^a   Garcia, Doroti O ^b   Mostardeiro, Marcelo ^a   Fanti, Karina S V N ^a   Levin, Anna S ^c  

^a HOSPITAL BRIGADEIRO   (Brazil)

^b INSTITUTO ADOLFO LUTZ   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Carbapenem resistant k. pneumoniae; Nosocomial outbreak; Polymyxin resistance

Indexed keywords

ANTIINFECTIVE AGENT; BACTERIAL DNA; BETA LACTAMASE; CARBAPENEM DERIVATIVE;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC RESISTANCE; ARTICLE; CHILD; CROSS INFECTION; DRUG EFFECT; EPIDEMIC; FEMALE; GENETICS; GENOTYPE; HUMAN; KLEBSIELLA INFECTION; KLEBSIELLA PNEUMONIAE; MALE; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MIDDLE AGED; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PULSED FIELD GEL ELECTROPHORESIS; TERTIARY HEALTH CARE; VERY ELDERLY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CARBAPENEMS; CHILD; CHILD, PRESCHOOL; CROSS INFECTION; DISEASE OUTBREAKS; DNA, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; FEMALE; GENOTYPE; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; POLYMERASE CHAIN REACTION; TERTIARY CARE CENTERS; YOUNG ADULT;

KLEBSIELLA PNEUMONIAE;

EID: 84875467393     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/S0074-02762013000100019     Document Type: Article

References (15)

1. Antoniadou A, Kontopidou F, Poulakou G, Koratzanis E, Galani I, Papadomichelakis E, Kopterides P, Souli M, Armaganidis A, Giamarellou H 2007. Colistin-resistant isolates of Klebsiella pneumoniae emerging in intensive care unit patients: first report of a multiclonal cluster. J Antimicrob Chemother 59: 786-790.
2. Ben-David D, Maor Y, Keller N, Regev-Yochay G, Tal I, Shachar D, Zlotkin A, Smollan G, Rahav G 2010. Potential role of active surveillance in the control of a hospital-wide outbreak of carbapenem-resistant Klebsiella pneumoniae infection. Infect Control Hosp Epidemiol 31: 620-626.
3. CLSI - Clinical and Laboratory Standards Institute 2010. Performance standards for antimicrobial susceptibility testing, 20th informational supplement, CLSI document M100-S20, CLSI, Wayne, USA, 153 pp.
4. Gautom RK 1997. Rapid pulsed-field gel electrophoresis protocol for typing of Escherichia coli O157:H7 and other Gram negative organisms in 1 day. J Clin Microbiol 35: 2977-2980.
5. Lee J, Patel G, Huprikar S, Calfee DP, Jenkins SG 2009. Decreased susceptibility to polymyxin B during treatment for carbapenem-resistant Klebsiella pneumoniae infection. J Clin Microbiol 47: 1611-1612.
6. Maltezou HC 2009. Metallo-beta-lactamases in Gram-negative bacteria: introducing the era of pan-resistance? Int J Antimicrob Agents 33: 405-e1-7.
7. Peirano G, Seki LM, Val Passos VL, MCFG Pinto, Guerra LR, Asensi MD 2009. Carbapenem-hydrolysing b-lactamase KPC-2 in Klebsiella pneumoniae isolated in Rio de Janeiro, Brazil. J Anticrob Chemother 63: 265-268.
8. Pereira GH, Garcia DO, Mostardeiro M, Ogassavara CT, Levin AS 2011. Spread of carbapenem-resistant Klebsiella pneumoniae in a tertiary hospital in São Paulo, Brazil. J Hosp Infect 79: 182-183.
9. Rasheed JK, Biddle JW, Anderson KF, Washer L, Chenoweth C, Perrin J, Newton DW, Patel JB 2008. Detection of the Klebsiella pneumoniae carbapenemase type 2 carbapenem-hydrolyzing enzyme in clinical isolates of Citrobacter freundii and K. oxytoca carrying a common plasmid. J Clin Microbiol 46: 2066-2069.
10. Seki LM, Pereira PS, de Souza M da P, Conceição M de S, Marques EA, Porto CO, Colnago EM, Alves C de F, Gomes D, Assef AP, Samuelsen Ø, Asensi MD 2011. Molecular epidemiology of KPC-2-producing Klebsiella pneumoniae isolates in Brazil: the predominance of sequence type 437. Diagn Microbiol Infect Dis 70: 274-277.
11. Souli M, Galani I, Antoniadou A, Papadomichelakis E, Poulakou G, Panagea T, Vourli S, Zerva L, Armaganidis A, Kanellakopoulou K, Giamarellou H 2010. An outbreak of infection due to beta-lactamase Klebsiella pneumoniae carbapenemase 2-producing K. pneumoniae in a Greek University Hospital: molecular characterization, epidemiology and outcomes. Clin Infect Dis 50: 364-373.
12. Souli M, Kontopidou FV, Papadomichelakis E, Galani I, Armaganidis A, Giamarellou H 2008. Clinical experience of serious infections caused by Enterobacteriaceae producing VIM-1 metallo-beta-lactamase in a Greek University Hospital. Clin Infect Dis 46: 847-854.
13. Suh JY, Son JS, Chung DR, Peck KR, Ko KS, Song JH 2010. Nonclonal emergence of colistin-resistant Klebsiella pneumoniae isolates from blood samples in South Korea. Antimicrob Agents Chemother 54: 560-562.
14. Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH, Swaminathan B 1995. Interpreting chromossomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 33: 2233-2239.
15. Wiener-Well Y, Rudensky B, Yinnon AM, Kopuit P, Schlesinger Y, Broide E, Lachish T, Raveh DJ 2010. Carriage rate of carbapenem-resistant Klebsiella pneumoniae in hospitalised patients during a national outbreak. J Hosp Infect 74: 344-349.