Carbapenem-hydrolysing β-lactamase KPC-2 in Klebsiella pneumoniae isolated in Rio de Janeiro, Brazil

Journal of Antimicrobial Chemotherapy

Volumn 63, Issue 2, 2009, Pages 265-268

  Peirano, Gisele ^a   Seki, Liliane M ^a   Val Passos, Vera Lúcia ^b   Pinto, Maria Cristina F G ^c   Guerra, Lília R ^c   Asensi, Marise D ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b HOSPITAL GERAL DE BONSUCESSO   (Brazil)

^c HOSPITAL UNIVERSITÁRIO ANTÔNIO PEDRO   (Brazil)

Author keywords

Class 1 integrons; Multidrug resistance; PCR; PFGE

Indexed keywords

AMIKACIN; AZTREONAM; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; BETA LACTAMASE CTX M 2; BETA LACTAMASE CTX M 8; BETA LACTAMASE IMP; BETA LACTAMASE KPC 2; BETA LACTAMASE SHV; BETA LACTAMASE VIM; CARBAPENEM; CARBAPENEMASE; CEFEPIME; CEFOTAXIME; CEFTAZIDIME; CIPROFLOXACIN; ERTAPENEM; EXTENDED SPECTRUM BETA LACTAMASE; GENTAMICIN; IMIPENEM; MEROPENEM; METALLO BETA LACTAMASE; PIPERACILLIN PLUS TAZOBACTAM; POLYMYXIN B; TIGECYCLINE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATION; BRAZIL; DNA SEQUENCE; ENZYME SYNTHESIS; INTEGRON; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PULSED FIELD GEL ELECTROPHORESIS;

ANTI-BACTERIAL AGENTS; BACTERIAL TYPING TECHNIQUES; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; BETA-LACTAMS; BRAZIL; CROSS INFECTION; DNA, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; GENOTYPE; HUMANS; INTEGRONS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TESTS; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA;

EID: 58849090055     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkn484     Document Type: Article

References (10)

1. Queenan AM, Bush K. Carbapenemases: The versatile β-lactamases. Clin Microbiol Rev 2007; 20: 440-58.
2. Walther-Rasmussen J, Høiby N. Class A carbapenemases. J Antimicrob Chemother 2007; 60: 470-82.
3. Woodford N, Tierno PM Jr, Young K et al. Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A β-lactamase, KPC-3, in a New York medical center. Antimicrob Agents Chemother 2004; 48: 4793-9.
4. Yigit H, Queenan AM, Anderson GJ et al. Novel carbapenemhydrolyzing β-lactamase KPC-1 from a carbapenem-resistant strain of Klebsiella pneumoniae. Antimicrob Agents Chemother 2001; 45: 1151-61.
5. Monteiro J, Henriques APC, Santos AF et al. Carbapenem-resistant Klebsiella pneumoniae outbreak: Emergence of KPC-2-producing strains in Brazil. In: Abstracts of the Forty-seventh Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, IL, 2007 Oral presentation C2-1929, p. 141. American Society for Microbiology, Washington, DC, USA.
6. Anderson KF, Lonsway DR, Rasheed JK et al. Evaluation of methods to identify the Klebsiella pneumoniae carbapenemase in Enterobacteriaceae. J Clin Microbiol 2007; 45: 2723-5.
7. Bonnet R, Sampaio JLM, Labia R et al. A novel CTX-M β-lactamase (CTX-M-8) in cefotaxime-resistant Enterobacteriaceae isolated in Brazil. Antimicrob Agents Chemother 2000; 44: 1936-42.
8. Canton R, Coque TM. The CTX-M b-lactamase pandemic. Curr Opin Microbiol 2006; 9: 466-75.
9. Villegas MV, Kattan JN, Quinteros MG et al. Prevalence of extended-spectrum β-lactamases in South America. Clin Microbiol Infect 2008; 14 Suppl 1: 154-8.
10. Fonseca EL, Freitas FS, Amorim FC et al. Detection of new arr-4 and arr-5 gene cassettes in clinical Pseudomonas aeruginosa and Klebsiella pneumoniae strains from Brazil. Antimicrob Agents Chemother 2008; 52: 1865-7.