Cost-effectiveness of enhancing adherence to therapy with blood pressure-lowering drugs in the setting of primary cardiovascular prevention

Value in Health

Volumn 16, Issue 2, 2013, Pages 318-324

  Scotti, Lorenza ^a   Baio, Gianluca ^a   Merlino, Luca ^b   Cesana, Giancarlo ^a   Mancia, Giuseppe ^a,c   Corrao, Giovanni ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b Operative Unit of Territorial Health Services   (Italy)

^c SAN GERARDO HOSPITAL   (Italy)

Author keywords

adherence; administrative database; blood pressure lowering drugs; cardiovascular events; cost effectiveness

Indexed keywords

ANTIHYPERTENSIVE AGENT;

ADULT; AGED; ARTICLE; CARDIOVASCULAR DISEASE; COMORBIDITY; CONFIDENCE INTERVAL; COST EFFECTIVENESS ANALYSIS; DRUG COST; FEMALE; FOLLOW UP; HOSPITALIZATION; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PRESCRIPTION; PRIMARY PREVENTION; PRIORITY JOURNAL;

ADULT; AGED; ANTIHYPERTENSIVE AGENTS; CEREBROVASCULAR DISORDERS; COHORT STUDIES; CORONARY DISEASE; COST-BENEFIT ANALYSIS; HUMANS; HYPERTENSION; ITALY; MEDICATION ADHERENCE; MIDDLE AGED; MODELS, ECONOMIC; PRIMARY PREVENTION; PROPORTIONAL HAZARDS MODELS;

EID: 84875445706     PISSN: 10983015     EISSN: 15244733     Source Type: Journal    
DOI: 10.1016/j.jval.2012.11.008     Document Type: Article

References (41)

1. G. Mancia, G. De Backer, and A. Dominiczak 2007 Guidelines for the management of arterial hypertension J Hypertens 25 2007 1105 1187
2. K. Wolf-Maier, R.S. Cooper, and H. Kramer Hypertension treatment and control in five European countries, Canada, and the United States Hypertension 43 2004 10 17
3. P.M. Kearney, M. Whelton, and K. Reynolds Worldwide prevalence of hypertension: a systematic review J Hypertens 22 2004 11 19
4. G. Mancia, and G. Grassi Systolic and diastolic blood pressure control in antihypertensive drug trials J Hypertens 20 2002 1461 1464
5. A.V. Chobanian, G.L. Bakris, and H.R. Black National High Blood Pressure Education Program Coordinating Committee. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure Hypertension 42 2003 1206 1252
6. M.A. Weber, S. Julius, and S.E. Kjeldsen Blood pressure dependent and independent effects of antihypertensive treatment on clinical events in the VALUE Trial Lancet 363 2004 2049 2051
7. N. Fitz-Simon, K. Bennett, and J. Feely A review of studies of adherence with antihypertensive drugs using prescription databases Ther Clin Risk Manag 1 2005 93 106
8. B. Vrijens, G. Vincze, and P. Kristanto Adherence to prescribed antihypertensive drug treatments: longitudinal study of electronically compiled dosing histories BMJ 336 2008 1114 1117
9. M.R. DiMatteo, P.J. Giordani, and H.S. Lepper Patient adherence and medical treatment outcomes: a meta-analysis Med Care 40 2002 794 811
10. G. Mazzaglia, E. Ambrosioni, and M. Alacqua Adherence to antihypertensive medications and cardiovascular morbidity among newly diagnosed hypertensive patients Circulation 120 2009 1598 1605
11. F.Z. Kettani, A. Dragomir, and R. Côté Impact of a better adherence to antihypertensive agents on cerebrovascular disease for primary prevention Stroke 40 2009 213 220
12. S. Perreault, A. Dragomir, and M. White Better adherence to antihypertensive agents and risk reduction of chronic heart failure J Intern Med 266 2009 207 218
13. S. Perreault, A. Dragomir, and L. Roy Adherence level of antihypertensive agents in coronary artery disease Br J Clin Pharmacol 69 2010 74 84
14. A. Dragomir, R. Côté, and L. Roy Impact of adherence to antihypertensive agents on clinical outcomes and hospitalization costs Med Care 48 2010 418 425
15. G. Corrao, A. Parodi, and F. Nicotra Better compliance to antihypertensive medications reduces cardiovascular risk J Hypertens 29 2011 610 618
16. H.P. McDonald, A. Garg, and R.B. Haynes Interventions to enhance patient adherence to medication prescriptions: scientific review JAMA 288 2002 2868 2879
17. M.F. Drummond, B. O'Brien, and G.L. Stoddart Methods for the Economic Evaluation of Health Care Programmes 2nd ed.) 1997 Oxfordrk: Oxford University Press
18. G. Corrao, G. Cesana, and L. Merlino Pharmacoepidemiological research and the linking of electronic healthcare databases available in the Italian region of Lombardy BioMed Stat Clin Epidemiol 2 2008 117 125
19. M.R. DiMatteo, P.J. Giordani, and H.S. Lepper Patient adherence and medical treatment outcomes: a meta-analysis Med Care 40 2002 794 811
20. L.K. Newby, N.M. LaPointe, and A.Y. Chen Long-term adherence to evidence-based secondary prevention therapies in coronary artery disease Circulation 113 2006 203 212
21. H. Tunstall-Pedoe, K. Kuulasmaa, and P. Amouyel Myocardial infarction and coronary deaths in the World Health Organization MONICA Project: registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four continents Circulation 90 1994 583 612
22. K. Asplund, R. Bonita, and K. Kuulasmaa Multinational comparisons of stroke epidemiology: evaluation of case ascertainment in the WHO MONICA stroke study Stroke 26 1995 355 360
23. R.A. Deyo, D.C. Cherkin, and M.A. Ciol Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases J Clin Epidemiol 45 1992 613 619
24. E. Marubini, and M.G. Valsecchi Analysing Survival Data from Clinical Trials and Observational Studies 1995 John Wiley & Sons New York
25. C.P. Robert Simulation of truncated normal variables Stat Comput 5 1995 121 125
26. A.S. Detsky, and A. Laupacis Relevance for cost-effectiveness analysis to clinicians and policy makers JAMA 298 2007 221 224
27. H. Wang, and H. Zhao A study on confidence intervals for incremental cost-effectiveness ratios Biometr J 50 2008 505 514
28. L.G. Mantovani, C. Fornari, and F. Madotto Burden of acute myocardial infarction Int J Cardiol 150 2011 111 112
29. P.L. Kolominsky-Rabas, P.U. Heuschmann, and D. Marschall Lifetime cost of ischemic stroke in Germany: results and national projections from a population-based stroke registry: the Erlangen Stroke Project Stroke 37 2006 1179 1183
30. B.L.G. Van Wijk, O.H. Klungel, E.R. Heerdink, and A. de Boer Generic substitution of antihypertensive drugs: does it affect adherence? Ann Pharmacother 40 2006 15 20
31. G. Corrao, A. Zambon, and A. Parodi Incidence of cardiovascular events in Italian patients with early discontinuations of antihypertensive, lipid-lowering, and antidiabetic treatments Am J Hypertens 25 2012 549 555
32. G. Corrao, A. Zambon, and F. Nicotra Persistence with oral and transdermal hormone replacement therapy and hospitalisation for cardiovascular outcomes Maturitas 57 2007 315 324
33. G. Corrao, A. Parodi, and A. Zambon Reduced discontinuation of antihypertensive treatment by two-drug combination as first step: evidence from daily life practice J Hypertens 28 2010 1584 1590
34. G. Corrao, V. Conti, and L. Merlino Results of a retrospective database analysis of adherence to statin therapy and risk of nonfatal ischemic heart disease in daily clinical practice in Italy Clin Ther 32 2010 300 310
35. Danzon PM, Furukawa MF. International prices and availability of pharmaceuticals in 2005: drugs spending differences reflect availability and use, not just prices. Health Affairs 2011;27:221-33.
36. H. Tunstall-Pedoe, K. Kuulasmaa, and H. Tolonen, for the WHO MONICA Project. MONICA H. Tunstall-Pedoe, Monograph and Multimedia Source Book. Genevea: 2003 World Health Organization
37. R.H. Chapman, C.P. Ferrufino, and S.L. Kowal The cost and effectiveness of adherence-improving interventions for antihypertensive and lipid-lowering drugs Int J Clin Pract 64 2010 169 181
38. E. Poluzzi, P. Strahinja, and A. Vargiu Initial treatment of hypertension and adherence to therapy in general practice in Italy Eur J Clin Pharmacol 61 2005 603 609
39. F. Turnbull Blood Pressure Lowering Treatment Trialists' Collaboration. Effect of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials Lancet 362 2003 1527 1535
40. K.T. Copeland, H. Checkoway, A.J. McMichael, and R.H. Holbrook Bias due to misclassification in the estimation of relative risk Am J Epidemiol 105 1977 488 495
41. M.A. Brookhart, A.R. Patrick, and C. Dormuth Adherence to lipid-lowering therapy and the use of preventive health services: an investigation of the healthy user effect Am J Epidemiol 166 2007 348 354