Novel 5-(benzyloxy)pyridin-2(1H)-one derivatives as potent c-Met inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 8, 2013, Pages 2408-2413

  Zhang, Dengyou ^a   Ai, Jing ^a   Liang, Zhongjie ^b   Zhu, Wei ^a   Peng, Xia ^a   Chen, Xianjie ^a   Ji, Yinchun ^a   Jiang, Hualiang ^a,c   Luo, Cheng ^a   Geng, Meiyu ^a   Liu, Hong ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b SOOCHOW UNIVERSITY   (China)

^c EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

c Met; EBC 1 cell; Tyrosine kinase receptor

Indexed keywords

AMIDE; BENZIMIDAZOLE DERIVATIVE; PYRIDONE DERIVATIVE; SCATTER FACTOR RECEPTOR;

ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; IC 50; MOLECULAR DOCKING;

CELL LINE, TUMOR; DRUG DESIGN; HUMANS; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-MET; PYRIDONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84875424710     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.02.037     Document Type: Article

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