Antimicrobial photodynamic therapy with RLP068 kills methicillin-resistant Staphylococcus aureus and improves wound healing in a mouse model of infected skin abrasion PDT with RLP068/Cl in infected mouse skin abrasion

Journal of Biophotonics

Volumn 6, Issue 9, 2013, Pages 733-742

  Vecchio, Daniela ^a,b   Dai, Tianhong ^a   Huang, Liyi ^a,b,c   Fantetti, Lia ^d   Roncucci, Gabrio ^d   Hamblin, Michael R ^a,b,e  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c GUANGXI MEDICAL UNIVERSITY   (China)

^d Molteni Therapeutics srl   (Italy)

^e HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

Author keywords

Antimicrobial photodynamic therapy; Cationic zinc phthalocyanine bioluminescence imaging; Methicillin resistant Staphylococcus aureus; Skin abrasion; Skin and soft tissue infection; Wound healing

Indexed keywords

BACTERIAL INACTIVATION; BIOLUMINESCENCE IMAGING; DRUG-RESISTANT BACTERIA; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; PHOTODYNAMIC THERAPY (PDT); SOFT TISSUE INFECTIONS; WOUND HEALING; WOUND HEALING PROCESS;

ABRASION; BIOLUMINESCENCE; MAMMALS; PHOSPHORESCENCE; PHOTODYNAMIC THERAPY; TISSUE; TRIBOLOGY; ZINC COMPOUNDS;

BACTERIA;

ANTIINFECTIVE AGENT; INDOLE DERIVATIVE; ORGANOMETALLIC COMPOUND; PHOTOSENSITIZING AGENT; RLP068; TOLONIUM CHLORIDE;

ANIMAL; ANTIMICROBIAL PHOTODYNAMIC THERAPY; ARTICLE; BAGG ALBINO MOUSE; CATIONIC ZINC PHTHALOCYANINE BIOLUMINESCENCE IMAGING; DISEASE MODEL; DRUG EFFECT; FEMALE; LUMINESCENCE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOUSE; PHOTOCHEMOTHERAPY; PHYSIOLOGY; SKIN ABRASION; SKIN AND SOFT TISSUE INFECTION; STAPHYLOCOCCAL SKIN INFECTION; WOUND HEALING;

ANTIMICROBIAL PHOTODYNAMIC THERAPY; CATIONIC ZINC PHTHALOCYANINE BIOLUMINESCENCE IMAGING; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; SKIN ABRASION; SKIN AND SOFT TISSUE INFECTION; WOUND HEALING;

ANIMALS; ANTI-INFECTIVE AGENTS; DISEASE MODELS, ANIMAL; FEMALE; INDOLES; LUMINESCENT MEASUREMENTS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICE; MICE, INBRED BALB C; ORGANOMETALLIC COMPOUNDS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; STAPHYLOCOCCAL SKIN INFECTIONS; TOLONIUM CHLORIDE; WOUND HEALING;

EID: 84875416768     PISSN: 1864063X     EISSN: 18640648     Source Type: Journal    
DOI: 10.1002/jbio.201200121     Document Type: Article

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