Effects of calcium binding and the hypertrophic cardiomyopathy A8V mutation on the dynamic equilibrium between closed and open conformations of the regulatory N-domain of isolated cardiac troponin C

Biochemistry

Volumn 52, Issue 11, 2013, Pages 1950-1962

  Cordina, Nicole M ^a   Liew, Chu K ^b,d   Gell, David A ^b,e   Fajer, Piotr G ^c   MacKay, Joel P ^b   Brown, Louise J ^a  

^a MACQUARIE UNIVERSITY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c FLORIDA STATE UNIVERSITY   (United States)

^d VICTOR CHANG CARDIAC RESEARCH INSTITUTE   (Australia)

^e UNIVERSITY OF TASMANIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIAC TROPONIN C; DYNAMIC EQUILIBRIA; FAMILIAL HYPERTROPHIC CARDIOMYOPATHIES; HYDROPHOBIC PATCH; HYPERTROPHIC CARDIOMYOPATHY; OPEN CONFORMATION; PARAMAGNETIC RELAXATION ENHANCEMENTS; STRUCTURAL EFFECT;

CALCIUM; MUSCLE; PARAMAGNETISM; POPULATION STATISTICS;

CONFORMATIONS;

CALCIUM; CYSTEINE; MAGNESIUM ION; TROPONIN C;

ANALYSIS; ARTICLE; BINDING AFFINITY; CALCIUM BINDING; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; HEART MUSCLE CELL; HYPERTROPHIC CARDIOMYOPATHY; MUTATION; NONHUMAN; PARAMAGNETIC RELAXATION ENHANCEMENT; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; RAT;

ANIMALS; CALCIUM; CARDIOMYOPATHY, HYPERTROPHIC; CHICKENS; HUMANS; MODELS, MOLECULAR; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; RATS; TROPONIN C;

EID: 84875416080     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi4000172     Document Type: Article

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