메뉴 건너뛰기




Volumn 8, Issue 3, 2013, Pages

The Tumor-Suppressive miR-497-195 Cluster Targets Multiple Cell-Cycle Regulators in Hepatocellular Carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; CYCLIN D3; CYCLIN DEPENDENT KINASE 4; MICRORNA; MICRORNA 101; MICRORNA 195; MICRORNA 378; MICRORNA 497; PROTEIN CCNE1; PROTEIN CDC25A; TUMOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84875413595     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060155     Document Type: Article
Times cited : (133)

References (33)
  • 2
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B, Kinzler KW, (2004) Cancer genes and the pathways they control. Nat Med 10: 789-799.
    • (2004) Nat Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 3
    • 0037025173 scopus 로고    scopus 로고
    • Cancer. Addiction to oncogenes-the Achilles heal of cancer
    • Weinstein IB, (2002) Cancer. Addiction to oncogenes-the Achilles heal of cancer. Science 297: 63-64.
    • (2002) Science , vol.297 , pp. 63-64
    • Weinstein, I.B.1
  • 4
    • 0038647568 scopus 로고    scopus 로고
    • Consequences of nonadaptive alterations in cancer
    • Kamb A, (2003) Consequences of nonadaptive alterations in cancer. Mol Biol Cell 14: 2201-2205.
    • (2003) Mol Biol Cell , vol.14 , pp. 2201-2205
    • Kamb, A.1
  • 5
    • 37249003928 scopus 로고    scopus 로고
    • Oncogene addiction: setting the stage for molecularly targeted cancer therapy
    • Sharma SV, Settleman J, (2007) Oncogene addiction: setting the stage for molecularly targeted cancer therapy. Genes Dev 21: 3214-3231.
    • (2007) Genes Dev , vol.21 , pp. 3214-3231
    • Sharma, S.V.1    Settleman, J.2
  • 6
    • 25444497278 scopus 로고    scopus 로고
    • The concept of synthetic lethality in the context of anticancer therapy
    • Kaelin WG Jr, (2005) The concept of synthetic lethality in the context of anticancer therapy. Nat Rev Cancer 5: 689-698.
    • (2005) Nat Rev Cancer , vol.5 , pp. 689-698
    • Kaelin Jr, W.G.1
  • 7
    • 80155191242 scopus 로고    scopus 로고
    • Oncogene addiction as a foundational rationale for targeted anti-cancer therapy: promises and perils
    • Torti D, Trusolino L, (2011) Oncogene addiction as a foundational rationale for targeted anti-cancer therapy: promises and perils. EMBO Mol Med 3: 623-636.
    • (2011) EMBO Mol Med , vol.3 , pp. 623-636
    • Torti, D.1    Trusolino, L.2
  • 8
    • 84858126071 scopus 로고    scopus 로고
    • MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review
    • Iorio MV, Croce CM, (2012) MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review. EMBO Mol Med 4: 143-159.
    • (2012) EMBO Mol Med , vol.4 , pp. 143-159
    • Iorio, M.V.1    Croce, C.M.2
  • 9
    • 78751477191 scopus 로고    scopus 로고
    • Gene silencing by microRNAs: contributions of translational repression and mRNA decay
    • Huntzinger E, Izaurralde E, (2011) Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat Rev Genet 12: 99-110.
    • (2011) Nat Rev Genet , vol.12 , pp. 99-110
    • Huntzinger, E.1    Izaurralde, E.2
  • 10
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • Bartel DP, (2009) MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 11
    • 33748928159 scopus 로고    scopus 로고
    • The diverse functions of microRNAs in animal development and disease
    • Kloosterman WP, Plasterk RH, (2006) The diverse functions of microRNAs in animal development and disease. Dev Cell 11: 441-450.
    • (2006) Dev Cell , vol.11 , pp. 441-450
    • Kloosterman, W.P.1    Plasterk, R.H.2
  • 12
    • 77953286512 scopus 로고    scopus 로고
    • Roles of small RNAs in tumor formation
    • Di Leva G, Croce CM, (2010) Roles of small RNAs in tumor formation. Trends Mol Med 16: 257-267.
    • (2010) Trends Mol Med , vol.16 , pp. 257-267
    • Di Leva, G.1    Croce, C.M.2
  • 13
    • 59149098054 scopus 로고    scopus 로고
    • MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity
    • Su H, Yang JR, Xu T, Huang J, Xu L, et al. (2009) MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity. Cancer Res 69: 1135-1142.
    • (2009) Cancer Res , vol.69 , pp. 1135-1142
    • Su, H.1    Yang, J.R.2    Xu, T.3    Huang, J.4    Xu, L.5
  • 14
    • 67651154718 scopus 로고    scopus 로고
    • MicroRNA-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells
    • Xu T, Zhu Y, Xiong Y, Ge YY, Yun JP, et al. (2009) MicroRNA-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells. Hepatology 50: 113-121.
    • (2009) Hepatology , vol.50 , pp. 113-121
    • Xu, T.1    Zhu, Y.2    Xiong, Y.3    Ge, Y.Y.4    Yun, J.P.5
  • 15
    • 27244433702 scopus 로고    scopus 로고
    • Real-time expression profiling of microRNA precursors in human cancer cell lines
    • Jiang J, Lee EJ, Gusev Y, Schmittgen TD, (2005) Real-time expression profiling of microRNA precursors in human cancer cell lines. Nucleic Acids Res 33: 5394-5403.
    • (2005) Nucleic Acids Res , vol.33 , pp. 5394-5403
    • Jiang, J.1    Lee, E.J.2    Gusev, Y.3    Schmittgen, T.D.4
  • 16
    • 38049103266 scopus 로고    scopus 로고
    • MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression
    • Lee DY, Deng Z, Wang CH, Yang BB, (2007) MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression. Proc Natl Acad Sci U S A 104: 20350-20355.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 20350-20355
    • Lee, D.Y.1    Deng, Z.2    Wang, C.H.3    Yang, B.B.4
  • 17
    • 77951491191 scopus 로고    scopus 로고
    • MicroRNAs control hepatocyte proliferation during liver regeneration
    • Song G, Sharma AD, Roll GR, Ng R, Lee AY, et al. (2010) MicroRNAs control hepatocyte proliferation during liver regeneration. Hepatology 51: 1735-1743.
    • (2010) Hepatology , vol.51 , pp. 1735-1743
    • Song, G.1    Sharma, A.D.2    Roll, G.R.3    Ng, R.4    Lee, A.Y.5
  • 18
    • 59149091973 scopus 로고    scopus 로고
    • Potentially important microRNA cluster on chromosome 17p13.1 in primary peritoneal carcinoma
    • Flavin RJ, Smyth PC, Laios A, O'Toole SA, Barrett C, et al. (2009) Potentially important microRNA cluster on chromosome 17p13.1 in primary peritoneal carcinoma. Mod Pathol 22: 197-205.
    • (2009) Mod Pathol , vol.22 , pp. 197-205
    • Flavin, R.J.1    Smyth, P.C.2    Laios, A.3    O'Toole, S.A.4    Barrett, C.5
  • 19
    • 79953330808 scopus 로고    scopus 로고
    • Analysis of MiR-195 and MiR-497 expression, regulation and role in breast cancer
    • Li D, Zhao Y, Liu C, Chen X, Qi Y, et al. (2011) Analysis of MiR-195 and MiR-497 expression, regulation and role in breast cancer. Clin Cancer Res 17: 1722-1730.
    • (2011) Clin Cancer Res , vol.17 , pp. 1722-1730
    • Li, D.1    Zhao, Y.2    Liu, C.3    Chen, X.4    Qi, Y.5
  • 20
    • 47249091921 scopus 로고    scopus 로고
    • The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
    • Korpal M, Lee ES, Hu G, Kang Y, (2008) The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 283: 14910-14914.
    • (2008) J Biol Chem , vol.283 , pp. 14910-14914
    • Korpal, M.1    Lee, E.S.2    Hu, G.3    Kang, Y.4
  • 21
    • 63249099917 scopus 로고    scopus 로고
    • Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer
    • Kim YK, Yu J, Han TS, Park SY, Namkoong B, et al. (2009) Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer. Nucleic Acids Res 37: 1672-1681.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1672-1681
    • Kim, Y.K.1    Yu, J.2    Han, T.S.3    Park, S.Y.4    Namkoong, B.5
  • 22
    • 77957225240 scopus 로고    scopus 로고
    • Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death
    • Zhang X, Wang X, Zhu H, Zhu C, Wang Y, et al. (2010) Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death. J Mol Cell Cardiol 49: 841-850.
    • (2010) J Mol Cell Cardiol , vol.49 , pp. 841-850
    • Zhang, X.1    Wang, X.2    Zhu, H.3    Zhu, C.4    Wang, Y.5
  • 23
    • 63849206509 scopus 로고    scopus 로고
    • Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues
    • Guo J, Miao Y, Xiao B, Huan R, Jiang Z, et al. (2009) Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues. J Gastroenterol Hepatol 24: 652-657.
    • (2009) J Gastroenterol Hepatol , vol.24 , pp. 652-657
    • Guo, J.1    Miao, Y.2    Xiao, B.3    Huan, R.4    Jiang, Z.5
  • 24
    • 67449087324 scopus 로고    scopus 로고
    • Identification of novel microRNA targets based on microRNA signatures in bladder cancer
    • Ichimi T, Enokida H, Okuno Y, Kunimoto R, Chiyomaru T, et al. (2009) Identification of novel microRNA targets based on microRNA signatures in bladder cancer. Int J Cancer 125: 345-352.
    • (2009) Int J Cancer , vol.125 , pp. 345-352
    • Ichimi, T.1    Enokida, H.2    Okuno, Y.3    Kunimoto, R.4    Chiyomaru, T.5
  • 25
    • 73349137922 scopus 로고    scopus 로고
    • miR-195 and miR-483-5p Identified as Predictors of Poor Prognosis in Adrenocortical Cancer
    • Soon PS, Tacon LJ, Gill AJ, Bambach CP, Sywak MS, et al. (2009) miR-195 and miR-483-5p Identified as Predictors of Poor Prognosis in Adrenocortical Cancer. Clin Cancer Res 15: 7684-7692.
    • (2009) Clin Cancer Res , vol.15 , pp. 7684-7692
    • Soon, P.S.1    Tacon, L.J.2    Gill, A.J.3    Bambach, C.P.4    Sywak, M.S.5
  • 27
    • 80052195502 scopus 로고    scopus 로고
    • Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer
    • Suzuki H, Takatsuka S, Akashi H, Yamamoto E, Nojima M, et al. (2011) Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer. Cancer Res 71: 5646-5658.
    • (2011) Cancer Res , vol.71 , pp. 5646-5658
    • Suzuki, H.1    Takatsuka, S.2    Akashi, H.3    Yamamoto, E.4    Nojima, M.5
  • 28
    • 77956937207 scopus 로고    scopus 로고
    • The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases
    • Finnerty JR, Wang WX, Hebert SS, Wilfred BR, Mao G, et al. (2010) The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases. J Mol Biol 402: 491-509.
    • (2010) J Mol Biol , vol.402 , pp. 491-509
    • Finnerty, J.R.1    Wang, W.X.2    Hebert, S.S.3    Wilfred, B.R.4    Mao, G.5
  • 29
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, et al. (2002) Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 99: 15524-15529.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3    Bichi, R.4    Zupo, S.5
  • 31
    • 77955497665 scopus 로고    scopus 로고
    • The role of the miR-200 family in epithelial-mesenchymal transition
    • Mongroo PS, Rustgi AK, (2010) The role of the miR-200 family in epithelial-mesenchymal transition. Cancer Biol Ther 10: 219-222.
    • (2010) Cancer Biol Ther , vol.10 , pp. 219-222
    • Mongroo, P.S.1    Rustgi, A.K.2
  • 32
    • 84863314557 scopus 로고    scopus 로고
    • Integrative Array-Based Approach Identifies MZB1 as a Frequently Methylated Putative Tumor Suppressor in Hepatocellular Carcinoma
    • Matsumura S, Imoto I, Kozaki KI, Matsui T, Muramatsu T, et al. (2012) Integrative Array-Based Approach Identifies MZB1 as a Frequently Methylated Putative Tumor Suppressor in Hepatocellular Carcinoma. Clin Cancer Res 18: 3541-3551.
    • (2012) Clin Cancer Res , vol.18 , pp. 3541-3551
    • Matsumura, S.1    Imoto, I.2    Kozaki, K.I.3    Matsui, T.4    Muramatsu, T.5
  • 33
    • 77952299722 scopus 로고    scopus 로고
    • miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma
    • Furuta M, Kozaki KI, Tanaka S, Arii S, Imoto I, et al. (2010) miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. Carcinogenesis 31: 766-776.
    • (2010) Carcinogenesis , vol.31 , pp. 766-776
    • Furuta, M.1    Kozaki, K.I.2    Tanaka, S.3    Arii, S.4    Imoto, I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.