메뉴 건너뛰기




Volumn 92, Issue 10, 2013, Pages 547-554

Hyperoxia and transforming growth factor β1 signaling in the post-ischemic mouse heart

Author keywords

Fibrosis; Hyperoxia; Ischemia reperfusion injury; Nitric oxide; Oximetry

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CARBOGEN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PROTEIN P21; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84875409959     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.01.018     Document Type: Article
Times cited : (7)

References (48)
  • 1
    • 0006372120 scopus 로고    scopus 로고
    • Fatal cardiac rupture among patients treated with thrombolytic agents and adjunctive thrombin antagonists: Observations from the thrombolysis and thrombin inhibition in myocardial infarction 9 study
    • R.C. Becker, J.S. Hochman, C.P. Cannon, F.A. Spencer, S.P. Ball, and M.J. Rizzo Fatal cardiac rupture among patients treated with thrombolytic agents and adjunctive thrombin antagonists: observations from the thrombolysis and thrombin inhibition in myocardial infarction 9 study J Am Coll Cardiol 33 1999 479 487
    • (1999) J Am Coll Cardiol , vol.33 , pp. 479-487
    • Becker, R.C.1    Hochman, J.S.2    Cannon, C.P.3    Spencer, F.A.4    Ball, S.P.5    Rizzo, M.J.6
  • 2
    • 16944366340 scopus 로고    scopus 로고
    • Complement C5a, TGF-beta 1, and MCP-1, in sequence, induce migration of monocytes into ischemic canine myocardium within the first one to five hours after reperfusion
    • H.H. Birdsall, D.M. Green, J. Trial, K.A. Youker, A.R. Burns, and C.R. MacKay Complement C5a, TGF-beta 1, and MCP-1, in sequence, induce migration of monocytes into ischemic canine myocardium within the first one to five hours after reperfusion Circulation 95 1997 684 692
    • (1997) Circulation , vol.95 , pp. 684-692
    • Birdsall, H.H.1    Green, D.M.2    Trial, J.3    Youker, K.A.4    Burns, A.R.5    MacKay, C.R.6
  • 3
    • 0030069832 scopus 로고    scopus 로고
    • The early and late phases of preconditioning against myocardial stunning and the essential role of oxyradicals in the late phase: An overview
    • R. Bolli The early and late phases of preconditioning against myocardial stunning and the essential role of oxyradicals in the late phase: an overview Basic Res Cardiol 91 1996 57 63
    • (1996) Basic Res Cardiol , vol.91 , pp. 57-63
    • Bolli, R.1
  • 4
    • 0027501246 scopus 로고
    • Limitation of infarct expansion and ventricular remodeling by late reperfusion. Study of time course and mechanism in a rat model
    • M.P. Boyle, and H.F. Weisman Limitation of infarct expansion and ventricular remodeling by late reperfusion. Study of time course and mechanism in a rat model Circulation 88 1993 2872 2883
    • (1993) Circulation , vol.88 , pp. 2872-2883
    • Boyle, M.P.1    Weisman, H.F.2
  • 5
    • 0029661975 scopus 로고    scopus 로고
    • Altered regulation of G1 cyclins in oxidant-induced growth arrest of lung alveolar epithelial cells. Accumulation of inactive cyclin E-DCK2 complexes
    • S. Corroyer, B. Maitre, V. Cazals, and A. Clement Altered regulation of G1 cyclins in oxidant-induced growth arrest of lung alveolar epithelial cells. Accumulation of inactive cyclin E-DCK2 complexes J Biol Chem 271 1996 25117 25125
    • (1996) J Biol Chem , vol.271 , pp. 25117-25125
    • Corroyer, S.1    Maitre, B.2    Cazals, V.3    Clement, A.4
  • 6
    • 0027212686 scopus 로고
    • Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
    • A. Desmouliere, A. Geinoz, F. Gabbiani, and G. Gabbiani Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts J Cell Biol 122 1993 103 111
    • (1993) J Cell Biol , vol.122 , pp. 103-111
    • Desmouliere, A.1    Geinoz, A.2    Gabbiani, F.3    Gabbiani, G.4
  • 7
    • 77956627158 scopus 로고    scopus 로고
    • Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction
    • M. Dobaczewski, M. Bujak, N. Li, C. Gonzalez-Quesada, L.H. Mendoza, and X.F. Wang Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction Circ Res 107 2010 418 428
    • (2010) Circ Res , vol.107 , pp. 418-428
    • Dobaczewski, M.1    Bujak, M.2    Li, N.3    Gonzalez-Quesada, C.4    Mendoza, L.H.5    Wang, X.F.6
  • 9
    • 0025978985 scopus 로고
    • Cardiac fibroblasts are predisposed to convert into myocyte phenotype: Specific effect of transforming growth factor beta
    • M. Eghbali, R. Tomek, C. Woods, and B. Bhambi Cardiac fibroblasts are predisposed to convert into myocyte phenotype: specific effect of transforming growth factor beta Proc Natl Acad Sci U S A 88 1991 795 799
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 795-799
    • Eghbali, M.1    Tomek, R.2    Woods, C.3    Bhambi, B.4
  • 10
    • 0023085856 scopus 로고
    • Alterations of the myocardial skeletal framework in acute myocardial infarction with and without ventricular rupture. A preliminary report
    • S.M. Factor, T.F. Robinson, R. Dominitz, and S.H. Cho Alterations of the myocardial skeletal framework in acute myocardial infarction with and without ventricular rupture. A preliminary report Am J Cardiovasc Pathol 1 1987 91 97
    • (1987) Am J Cardiovasc Pathol , vol.1 , pp. 91-97
    • Factor, S.M.1    Robinson, T.F.2    Dominitz, R.3    Cho, S.H.4
  • 11
    • 84866342680 scopus 로고    scopus 로고
    • Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease
    • D. Fan, A. Takawale, J. Lee, and Z. Kassiri Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease Fibrogenesis Tissue Repair 5 2012 15 28
    • (2012) Fibrogenesis Tissue Repair , vol.5 , pp. 15-28
    • Fan, D.1    Takawale, A.2    Lee, J.3    Kassiri, Z.4
  • 12
    • 0037293568 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning
    • P. Ferdinandy, and R. Schulz Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning Br J Pharmacol 138 2003 532 543
    • (2003) Br J Pharmacol , vol.138 , pp. 532-543
    • Ferdinandy, P.1    Schulz, R.2
  • 13
    • 33847724471 scopus 로고    scopus 로고
    • The mechanistic basis of infarct healing
    • N.G. Frangogiannis The mechanistic basis of infarct healing Antioxid Redox Signal 8 2006 1907 1939
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1907-1939
    • Frangogiannis, N.G.1
  • 14
    • 50249155297 scopus 로고    scopus 로고
    • Transforming growth factor beta inhibition increases mortality and left ventricular dilatation after myocardial infarction
    • S. Frantz, K. Hu, A. Adamek, J. Wolf, A. Sallam, and S.K. Maier Transforming growth factor beta inhibition increases mortality and left ventricular dilatation after myocardial infarction Basic Res Cardiol 103 2008 485 492
    • (2008) Basic Res Cardiol , vol.103 , pp. 485-492
    • Frantz, S.1    Hu, K.2    Adamek, A.3    Wolf, J.4    Sallam, A.5    Maier, S.K.6
  • 15
    • 0036882338 scopus 로고    scopus 로고
    • Mapping of the B1 field distribution of a surface coil resonator using EPR imaging
    • G. He, S.P. Evalappan, H. Hirata, Y. Deng, S. Petryakov, and P. Kuppusamy Mapping of the B1 field distribution of a surface coil resonator using EPR imaging Magn Reson Med 48 2002 1057 1062
    • (2002) Magn Reson Med , vol.48 , pp. 1057-1062
    • He, G.1    Evalappan, S.P.2    Hirata, H.3    Deng, Y.4    Petryakov, S.5    Kuppusamy, P.6
  • 17
    • 0018151143 scopus 로고
    • Infarct expansion versus extension: Two different complications of acute myocardial infarction
    • G.M. Hutchins, and B.H. Bulkley Infarct expansion versus extension: two different complications of acute myocardial infarction Am J Cardiol 41 1978 1127 1132
    • (1978) Am J Cardiol , vol.41 , pp. 1127-1132
    • Hutchins, G.M.1    Bulkley, B.H.2
  • 18
    • 0037372536 scopus 로고    scopus 로고
    • Remodeling of the myocardium and potential targets in the collagen degradation and synthesis pathways
    • B.I. Jugdutt Remodeling of the myocardium and potential targets in the collagen degradation and synthesis pathways Curr Drug Targets Cardiovasc Haematol Disord 3 2003 1 30
    • (2003) Curr Drug Targets Cardiovasc Haematol Disord , vol.3 , pp. 1-30
    • Jugdutt, B.I.1
  • 19
    • 0141653901 scopus 로고    scopus 로고
    • Ventricular remodeling after infarction and the extracellular collagen matrix: When is enough enough?
    • B.I. Jugdutt Ventricular remodeling after infarction and the extracellular collagen matrix: when is enough enough? Circulation 108 2003 1395 1403
    • (2003) Circulation , vol.108 , pp. 1395-1403
    • Jugdutt, B.I.1
  • 20
    • 0027424592 scopus 로고
    • Potential benefits of late reperfusion of infarcted myocardium. The open artery hypothesis
    • C.B. Kim, and E. Braunwald Potential benefits of late reperfusion of infarcted myocardium. The open artery hypothesis Circulation 88 1993 2426 2436
    • (1993) Circulation , vol.88 , pp. 2426-2436
    • Kim, C.B.1    Braunwald, E.2
  • 21
    • 44449090898 scopus 로고    scopus 로고
    • Inhibition of myocardial apoptosis by postconditioning is associated with attenuation of oxidative stress-mediated nuclear factor-kappa B translocation and TNF alpha release
    • H. Kin, N.P. Wang, J. Mykytenko, J. Reeves, J. Deneve, and R. Jiang Inhibition of myocardial apoptosis by postconditioning is associated with attenuation of oxidative stress-mediated nuclear factor-kappa B translocation and TNF alpha release Shock 29 2008 761 768
    • (2008) Shock , vol.29 , pp. 761-768
    • Kin, H.1    Wang, N.P.2    Mykytenko, J.3    Reeves, J.4    Deneve, J.5    Jiang, R.6
  • 22
    • 59549106445 scopus 로고    scopus 로고
    • Proteomic analysis of protein tyrosine nitration after ischemia reperfusion injury: Mitochondria as the major target
    • B. Liu, A.K. Tewari, L. Zhang, K.B. Green-Church, J.L. Zweier, and Y.R. Chen Proteomic analysis of protein tyrosine nitration after ischemia reperfusion injury: mitochondria as the major target Biochim Biophys Acta 1794 2009 476 485
    • (2009) Biochim Biophys Acta , vol.1794 , pp. 476-485
    • Liu, B.1    Tewari, A.K.2    Zhang, L.3    Green-Church, K.B.4    Zweier, J.L.5    Chen, Y.R.6
  • 23
    • 51349122603 scopus 로고    scopus 로고
    • Nitric oxide elicits functional MMP-13 protein-tyrosine nitration during wound repair
    • T.R. Lizarbe, C. Garcia-Rama, C. Tarin, M. Saura, E. Calvo, and J.A. Lopez Nitric oxide elicits functional MMP-13 protein-tyrosine nitration during wound repair FASEB J 22 2008 3207 3215
    • (2008) FASEB J , vol.22 , pp. 3207-3215
    • Lizarbe, T.R.1    Garcia-Rama, C.2    Tarin, C.3    Saura, M.4    Calvo, E.5    Lopez, J.A.6
  • 24
    • 0032501998 scopus 로고    scopus 로고
    • Peroxynitrite-mediated inactivation of manganese superoxide dismutase involves nitration and oxidation of critical tyrosine residues
    • L.A. MacMillan-Crow, J.P. Crow, and J.A. Thompson Peroxynitrite-mediated inactivation of manganese superoxide dismutase involves nitration and oxidation of critical tyrosine residues Biochemistry 37 1998 1613 1622
    • (1998) Biochemistry , vol.37 , pp. 1613-1622
    • MacMillan-Crow, L.A.1    Crow, J.P.2    Thompson, J.A.3
  • 25
    • 0030834159 scopus 로고    scopus 로고
    • Remodeling after myocardial infarction in humans is not associated with interstitial fibrosis of noninfarcted myocardium
    • M.M. Marijianowski, P. Teeling, and A.E. Becker Remodeling after myocardial infarction in humans is not associated with interstitial fibrosis of noninfarcted myocardium J Am Coll Cardiol 30 1997 76 82
    • (1997) J Am Coll Cardiol , vol.30 , pp. 76-82
    • Marijianowski, M.M.1    Teeling, P.2    Becker, A.E.3
  • 26
    • 34548424486 scopus 로고    scopus 로고
    • TGF-beta1 stimulates human AT1 receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathways
    • M.M. Martin, J.A. Buckenberger, J. Jiang, G.E. Malana, D.L. Knoell, and D.S. Feldman TGF-beta1 stimulates human AT1 receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathways Am J Physiol Lung Cell Mol Physiol 293 2007 L790 L799
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293
    • Martin, M.M.1    Buckenberger, J.A.2    Jiang, J.3    Malana, G.E.4    Knoell, D.L.5    Feldman, D.S.6
  • 27
    • 0037035465 scopus 로고    scopus 로고
    • Protection of myocytes from hypoxia-reoxygenation injury by nitric oxide is mediated by modulation of transforming growth factor-beta1
    • J.L. Mehta, H.J. Chen, and D.Y. Li Protection of myocytes from hypoxia-reoxygenation injury by nitric oxide is mediated by modulation of transforming growth factor-beta1 Circulation 105 2002 2206 2211
    • (2002) Circulation , vol.105 , pp. 2206-2211
    • Mehta, J.L.1    Chen, H.J.2    Li, D.Y.3
  • 28
    • 0023069839 scopus 로고
    • The collagens: An overview and update
    • E.J. Miller, and S. Gay The collagens: an overview and update Methods Enzymol 144 1987 3 41
    • (1987) Methods Enzymol , vol.144 , pp. 3-41
    • Miller, E.J.1    Gay, S.2
  • 29
    • 0141510019 scopus 로고    scopus 로고
    • Oxidative damage to mitochondrial complex i due to peroxynitrite: Identification of reactive tyrosines by mass spectrometry
    • J. Murray, S.W. Taylor, B. Zhang, S.S. Ghosh, and R.A. Capaldi Oxidative damage to mitochondrial complex I due to peroxynitrite: identification of reactive tyrosines by mass spectrometry J Biol Chem 278 2003 37223 37230
    • (2003) J Biol Chem , vol.278 , pp. 37223-37230
    • Murray, J.1    Taylor, S.W.2    Zhang, B.3    Ghosh, S.S.4    Capaldi, R.A.5
  • 30
    • 73449098557 scopus 로고    scopus 로고
    • Reperfusion injury, microvascular dysfunction, and cardioprotection: The "dark side" of reperfusion
    • A. Prasad, G.W. Stone, D.R. Holmes, and B. Gersh Reperfusion injury, microvascular dysfunction, and cardioprotection: the "dark side" of reperfusion Circulation 120 2009 2105 2112
    • (2009) Circulation , vol.120 , pp. 2105-2112
    • Prasad, A.1    Stone, G.W.2    Holmes, D.R.3    Gersh, B.4
  • 32
    • 0035103959 scopus 로고    scopus 로고
    • Effect of N-acetyl-seryl-aspartyl-lysyl-proline on DNA and collagen synthesis in rat cardiac fibroblasts
    • N.E. Rhaleb, H. Peng, P. Harding, M. Tayeh, M.C. LaPointe, and O.A. Carretero Effect of N-acetyl-seryl-aspartyl-lysyl-proline on DNA and collagen synthesis in rat cardiac fibroblasts Hypertension 37 2001 827 832
    • (2001) Hypertension , vol.37 , pp. 827-832
    • Rhaleb, N.E.1    Peng, H.2    Harding, P.3    Tayeh, M.4    Lapointe, M.C.5    Carretero, O.A.6
  • 33
    • 37049008897 scopus 로고    scopus 로고
    • P21waf1/cip1/sdi1 as a central regulator of inducible smooth muscle actin expression and differentiation of cardiac fibroblasts to myofibroblasts
    • S. Roy, S. Khanna, T. Rink, J. Radtke, W.T. Williams, and S. Biswas P21waf1/cip1/sdi1 as a central regulator of inducible smooth muscle actin expression and differentiation of cardiac fibroblasts to myofibroblasts Mol Biol Cell 18 2007 4837 4846
    • (2007) Mol Biol Cell , vol.18 , pp. 4837-4846
    • Roy, S.1    Khanna, S.2    Rink, T.3    Radtke, J.4    Williams, W.T.5    Biswas, S.6
  • 34
    • 77955872851 scopus 로고    scopus 로고
    • Fra-2 mediates oxygen-sensitive induction of transforming growth factor beta in cardiac fibroblasts
    • S. Roy, S. Khanna, A. Azad, R. Schnitt, G. He, and C. Weigert Fra-2 mediates oxygen-sensitive induction of transforming growth factor beta in cardiac fibroblasts Cardiovasc Res 87 2010 647 655
    • (2010) Cardiovasc Res , vol.87 , pp. 647-655
    • Roy, S.1    Khanna, S.2    Azad, A.3    Schnitt, R.4    He, G.5    Weigert, C.6
  • 36
    • 0034074371 scopus 로고    scopus 로고
    • Infarct scar: A dynamic tissue
    • Y. Sun, and K.T. Weber Infarct scar: a dynamic tissue Cardiovasc Res 46 2000 250 256
    • (2000) Cardiovasc Res , vol.46 , pp. 250-256
    • Sun, Y.1    Weber, K.T.2
  • 37
    • 0032799992 scopus 로고    scopus 로고
    • Clinical epidemiology of acute myocardial infarction
    • L. Tavazzi Clinical epidemiology of acute myocardial infarction Am Heart J 138 1999 S48 S54
    • (1999) Am Heart J , vol.138
    • Tavazzi, L.1
  • 38
    • 0031040522 scopus 로고    scopus 로고
    • Proteinases and myocardial extracellular matrix turnover
    • S.C. Tyagi Proteinases and myocardial extracellular matrix turnover Mol Cell Biochem 168 1997 1 12
    • (1997) Mol Cell Biochem , vol.168 , pp. 1-12
    • Tyagi, S.C.1
  • 40
    • 33646352472 scopus 로고    scopus 로고
    • Epidemiology of heart failure and left ventricular systolic dysfunction after acute myocardial infarction: Prevalence, clinical characteristics, and prognostic importance
    • R.A. Weir, J.J. McMurray, and E.J. Velazquez Epidemiology of heart failure and left ventricular systolic dysfunction after acute myocardial infarction: prevalence, clinical characteristics, and prognostic importance Am J Cardiol 97 2006 13F 25F
    • (2006) Am J Cardiol , vol.97
    • Weir, R.A.1    McMurray, J.J.2    Velazquez, E.J.3
  • 41
    • 0023411998 scopus 로고
    • Myocardial infarct expansion, infarct extension, and reinfarction: Pathophysiologic concepts
    • H.F. Weisman, and B. Healy Myocardial infarct expansion, infarct extension, and reinfarction: pathophysiologic concepts Prog Cardiovasc Dis 30 1987 73 110
    • (1987) Prog Cardiovasc Dis , vol.30 , pp. 73-110
    • Weisman, H.F.1    Healy, B.2
  • 42
    • 54349114052 scopus 로고    scopus 로고
    • Formation of hydrogen peroxide and reduction of peroxynitrite via dismutation of superoxide at reperfusion enhances myocardial blood flow and oxygen consumption in postischemic mouse heart
    • Y. Xu, B. Liu, J.L. Zweier, and G. He Formation of hydrogen peroxide and reduction of peroxynitrite via dismutation of superoxide at reperfusion enhances myocardial blood flow and oxygen consumption in postischemic mouse heart J Pharmacol Exp Ther 327 2008 402 410
    • (2008) J Pharmacol Exp Ther , vol.327 , pp. 402-410
    • Xu, Y.1    Liu, B.2    Zweier, J.L.3    He, G.4
  • 43
    • 0023520907 scopus 로고
    • Profound structural alterations of the extracellular collagen matrix in postischemic dysfunctional ("stunned") but viable myocardium
    • M.J. Zhao, H. Zhang, T.F. Robinson, S.M. Factor, E.H. Sonnenblick, and C. Eng Profound structural alterations of the extracellular collagen matrix in postischemic dysfunctional ("stunned") but viable myocardium J Am Coll Cardiol 10 1987 1322 1334
    • (1987) J Am Coll Cardiol , vol.10 , pp. 1322-1334
    • Zhao, M.J.1    Zhang, H.2    Robinson, T.F.3    Factor, S.M.4    Sonnenblick, E.H.5    Eng, C.6
  • 44
    • 20444494969 scopus 로고    scopus 로고
    • Endothelium-derived nitric oxide regulates postischemic myocardial oxygenation and oxygen consumption by modulation of mitochondrial electron transport
    • X. Zhao, G. He, Y.R. Chen, R.P. Pandian, P. Kuppusamy, and J.L. Zweier Endothelium-derived nitric oxide regulates postischemic myocardial oxygenation and oxygen consumption by modulation of mitochondrial electron transport Circulation 111 2005 2966 2972
    • (2005) Circulation , vol.111 , pp. 2966-2972
    • Zhao, X.1    He, G.2    Chen, Y.R.3    Pandian, R.P.4    Kuppusamy, P.5    Zweier, J.L.6
  • 45
    • 33847732229 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase (NOS3) knockout decreases NOS2 induction, limiting hyperoxygenation and conferring protection in the postischemic heart
    • X. Zhao, Y.R. Chen, G. He, A. Zhang, L.J. Druhan, and A.R. Strauch Endothelial nitric oxide synthase (NOS3) knockout decreases NOS2 induction, limiting hyperoxygenation and conferring protection in the postischemic heart Am J Physiol Heart Circ Physiol 292 2007 H1541 H1550
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Zhao, X.1    Chen, Y.R.2    He, G.3    Zhang, A.4    Druhan, L.J.5    Strauch, A.R.6
  • 46
    • 34548420201 scopus 로고    scopus 로고
    • Ischemic preconditioning prevents in vivo hyperoxygenation in postischemic myocardium with preservation of mitochondrial oxygen consumption
    • X. Zhu, B. Liu, S. Zhou, Y.R. Chen, Y. Deng, and J.L. Zweier Ischemic preconditioning prevents in vivo hyperoxygenation in postischemic myocardium with preservation of mitochondrial oxygen consumption Am J Physiol Heart Circ Physiol 293 2007 H1442 H1450
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Zhu, X.1    Liu, B.2    Zhou, S.3    Chen, Y.R.4    Deng, Y.5    Zweier, J.L.6
  • 47
    • 0000104045 scopus 로고
    • Measurement of endothelial cell free radical generation: Evidence for a central mechanism of free radical injury in postischemic tissues
    • J.L. Zweier, P. Kuppusamy, and G.A. Lutty Measurement of endothelial cell free radical generation: evidence for a central mechanism of free radical injury in postischemic tissues Proc Natl Acad Sci U S A 85 1988 4046 4050
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 4046-4050
    • Zweier, J.L.1    Kuppusamy, P.2    Lutty, G.A.3
  • 48
    • 0027938706 scopus 로고
    • Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation
    • J.L. Zweier, R. Broderick, P. Kuppusamy, S. Thompson-Gorman, and G.A. Lutty Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation J Biol Chem 269 1994 24156 24162
    • (1994) J Biol Chem , vol.269 , pp. 24156-24162
    • Zweier, J.L.1    Broderick, R.2    Kuppusamy, P.3    Thompson-Gorman, S.4    Lutty, G.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.