Atherosclerosis subclinical and inflammatory markers in obese and nonobese Children and adolescents;Aterosclerose subclínica e marcadores inflamatórios em crianças e adolescentes obesos e não obesos

Revista Brasileira de Epidemiologia

Volumn 15, Issue 4, 2012, Pages 804-816

  Silva, Larissa Rosa ^a,b   Stefanello, Joice M F ^a,b   Pizzi, Juliana ^a,b   Timossi, Luciana S ^a,b   Leite, Neiva ^a,b  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b NONE

Author keywords

Adiponectin; Atherosclerosis; C reactive protein; Child; Meta analysis; Obesity; Ultrasonography

Indexed keywords

BIOLOGICAL MARKER;

ADOLESCENT; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; BLOOD; CHILD; HUMAN; INFLAMMATION; META ANALYSIS (TOPIC); OBESITY; PATHOLOGY;

ADOLESCENT; ATHEROSCLEROSIS; BIOLOGICAL MARKERS; CAROTID INTIMA-MEDIA THICKNESS; CHILD; HUMANS; INFLAMMATION; META-ANALYSIS AS TOPIC; OBESITY;

EID: 84875383729     PISSN: 1415790X     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1415-790X2012000400012     Document Type: Article

References (40)

1. Heron M, Hoyert DL, Murphy SM, Xu J, Kochanek KD, Tejada-vera B. Deaths: Final Data for 2006. National Vital Statistics Report 2009; 57(14): 131-4.
2. Scherr C, Magalhães CK, Malheiros W. Análise do Perfil Lipídico em Escolares. Arq Bras Cardiol 2007, 89(2): 65-70.
3. MCvean JJ, Carrel AL, Eickhoff JC, Allen DB. Fitness Level and Body Composition are Associated with Inflammation in Non-obese Children. J Pediatr Endocrinol Metabol 2009; 22: 153-9.
4. Mcgill HCJr, Sachdev HP, Herderick EE, Mcmahan CA, Zieske AW, Malcolm GT et al. Atherosclerosis in youth. Minerva Pediatrica 2002; 54(5): 437-47.
5. Zhu W, Huang X, HE J, Li M, Neubauer H. Arterial intima-media thickening and endothelial dysfunction in obese Chinese children. Eur J Pediatr 2005; (164): 337-44.
6. Singhal A. Endothelial dysfunction: role in obesity-related disorders and the early origins of CVD. Proc Nutr Soc 2005; 64, 15-22.
7. Giannini C, Giorgis T, Scarinci A, Ciampani MP, Marcovecchio Ml, Chiarelli F et al. Obese related effects of inflammatory markers and insulin resistance on increased carotid intima media thickness in pre-pubertal children. Atherosclerosis 2008; 197: 448-56.
8. Brasil AR, Norton RC, Rossetti MB, Leão E, Mendes RP. C-reactive protein as an indicator of low intensity inflammation in children and adolescents with and without obesity. Obesity 2007; 83(5): 477-80.
9. Saltevo J, Vanhala M, Kautiainen H, Laakso M. Levels of adiponectin, C-reactive protein and interleukin-1 receptor antagonist are associated with the relative change in body mass index between childhood and adulthood. Diabetes Vasc Dis Res 2007; 4: 328-31.
10. Oliveira AC, Oliveira AM, Adan LF, Oliveira NF, Silva AM, Ladeia AM. C-reactive protein and metabolic syndrome in youth: a strong relationship? Obesity 2008; 16(5): 1094-8.
11. Juonala M, Viikari JS, Kähönen M, Solakivi T, Helenius H, Jula A et al. Childhood Levels of Serum Apolipoproteins B and A-I Predict Carotid Intima-Media Thickness and Brachial Endothelial Function in Adulthood: The Cardiovascular Risk in Young Finns Study. J Am Coll Cardiol 2008; 52(4): 293-9.
12. Pilz S, Horejsi R, Moller R, Almer G, Scharnagl H, Stojakovic T et al. Early Atherosclerosis in Obese Juveniles Is Associated with Low Serum Levels of Adiponectin. J Clin Endocrinol Metabol 2005; 90(8): 4792-6.
13. Beauloye V, Zech F, Mong HT, Clapuyt P, Maes M, Brichard SM. Determinants of Early Atherosclerosis in Obese Children and Adolescents. J Clin Endocrinol Metabol 2007; 92(8): 3025-32.
14. Jimenez MV, Estepa RM, Camacho RM, Estrada RC, Luna FG, Guitarte FB. Endothelial dysfunction is related to insulin resistance and inflammatory biomarker levels in obese prepubertal children. Eur J Endocrinol 2007; 156: 497-502.
15. Arnaiz P, Acevedo M, Barja S, Aglony M, Guzmán B, Cassis B et al. Adiponectin levels, cardiometabolic risk fators and markers of subclinical atherosclerosis in children. Int J Cardiol 2008; 138: 138-44.
16. Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. New Engl J Med 2000; 342: 836-43.
17. Petersen AM, Pedersen BK. The anti-inflammatory effect of exercise. J Appl Physiol 2005; 98: 1154-62.
18. Asayama K, Hayashibe H, Dobashi K, Uchida N, Nakane T, Kodera K et al. Decrease in serum adiponectin level due to obesity and visceral fat accumulation in children. Obes Res 2003; 11(9): 1072-9.
19. Cambuli VM, Musiu MC, Incani M, Paderi M, Serpe R, Marras V et al. Assessment of adiponectin and leptin as biomarkers of positive metabolic outcomes after lifestyle intervention in overweight and obese children. J Clin Endocrinol Metabol 2008; 93(8): 3051-7.
20. Nishimura R, Sano H, Matsudaira T, Morimoto A, Miyashita Y, Shirasawa T et al. Changes in body mass index, leptin and adiponectin in Japanese children during a three-year follow-up period: a population-based cohort study. Cardiovasc Diabetol 2009: 89(6): 2548-56.
21. Kapuku GK, Harshfield GA, Davis HC, Treiber FA. Early markers of cardiovascular disease. Vasc Pharmacol 2006; 45: 277-80.
22. Kumar V, Sachdev Hps, Khalil A. Noninvasive Evaluation of Endothelial Function and Arterial Mechanics in Overweight Adolescents. Indian Pediatr 2004; 41(11): 1105-14.
23. Demircioglu F, Koçyigit A, Arslan N, Hizli S, Sedat AT. Intima-media thickness of carotid artery and susceptibility to atherosclerosis in obese children with nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr 2008; 47(1): 68-75.
24. Kershaw EE, Flier JS. Adipose tissue as an endocrine organ. J Clin Endocrinol Metabol 2004; 89(6): 2548-56.
25. a ed. (português). Porto Alegre: Artmed; 2002.
26. Arnaíz P, Acevedo M, Barja S, Berríos X, Guzmán B, Bambs C et al. Subclinical atherosclerosis: classic and emerging cardiovascular risk factors in Chilean obese children. Rev Chil Pediatr 2007; 78(2): 135-42.
27. Verçoza AM, Baldisserotto M, Los Santos CA, Poli-De-Figueiredo CE, D'avila DO. Cardiovascular risk factors and carotid intima-media thickness in asymptomatic children. Pediatr Cardiol 2009; 30: 1055-60.
28. Meyer AA, Kundt G, Steiner M, Schuff-Werner P, Kienast W. Impaired flow-mediated vasodilation, carotid artery intima-media thickening, and elevated endothelial plasma markers in obese children: the impact of cardiovascular risk factors. Pediatrics 2006; 117: 1560-7.
29. Pacifico L, Cantisani V, Ricci P, Osborn JF, Schiavo E, Anania C, et al. Nonalcoholic fatty liver disease and carotid atherosclerosis in children. Pediatr Res 2008; 63(4): 423-7.
30. Giannini C, Giorgis T, Scarinci A, Cataldo I, Marcovecchio Ml, Chiarelli F, et al. Increased carotid intima-media thickness in pre-pubertal children with constitutional leanness and severe obesity: the speculative role of insulin sensitivity, oxidant status and chronic inflammation. Eur J Endocrinol 2009; 161(1): 73-80.
31. Mangge H, Schauenstein K, Stroedter L, Griesl A, Maerz W, Borkenstein M. Low grade inflammation in juvenile obesity and type 1 diabetes associated with early signs of atherosclerosis. Exper Clin Endocrinol Diabetes 2004;112(7): 378-82.
32. Mangge H, Almer G, Haj-Yahya S, Pilz S, Gasser R, Möller R et al. Preatherosclerosis and adiponectin subfractions in obese adolescents. Obesity (Silver Spring) 2008;16(12): 2578-84.
33. Mangge H, Almer G, Haj-Yahya S, Grandits N, Gasser R, Pilz S et al. Nuchal thickness of subcutaneous adipose tissue is tightly associated with an increased LMW/total adiponectin ratio in obese juveniles. Atherosclerosis 2009; 203(1): 277-83.
34. Wilders-Truschnig M, Mangge H, Lieners C, Gruber HJ, Mayer C, Marz W. IgG antibodies against food antigens are correlated with inflammation and intima media thickness in obese juveniles. Exper Clin Endocrinol Diabetes 2008; 116: 241-5.
35. Kelishadi R, Cook SR, Amrac B, Adibi A. Factors associated with insulin resistance and non-alcoholic fatty liver disease among youths. Atherosclerosis 2009; 204: 538-43.
36. Kapiotis S, Holzer G, Schaller G, Haumer M, Widhalm H, Weghuber D, et al. A proinflammatory state is detectable in obese children and is accompanied by functional and morphological vascular changes. Arterioscler Thromb Vasc Biol 2006; 26: 2541-6.
37. Sociedade Brasileira de Cardiologia. IV Diretriz Brasileira Sobre Dislipidemias e Prevenção da Aterosclerose. Arq Bras Cardiol 2007; 88 (S1): 3-22.
38. Freitas EV, Brandão AA, Pozzan R, Magalhães ME, Fonseca F, Pizzi O et al. Importância da HDL-c para a ocorrência de doença cardiovascular no idoso. Arq Bras Cardiol 2009; 93(3): 231-8.
39. Roh EJ, Lim JW, Ko KO, Cheon EJ. A useful predictor of early atherosclerosis in obese children: serum high-sensitivity c-reactive protein. J Korean Med Sci 2007; 22: 192-7.
40. Instituto Brasileiro de Geografia e Estatística: Pesquisa de Orçamentos Familiares 2008-2009. Brasília, DF. Disponível em: http://www.ibge.gov.br. [Acessado em 31 de agosto de 2010].