Vascular endothelial growth factor polymorphisms and risk of Alzheimer's disease: A meta-analysis

Gene

Volumn 518, Issue 2, 2013, Pages 296-302

  He, Dali ^a   Lu, Weiping ^b   Chang, Kai ^b   Liu, Yueliang ^a   Zhang, Jun ^a   Zeng, Zhaofang ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Genetic polymorphism; Meta analysis; Vascular endothelial growth factor

Indexed keywords

VASCULOTROPIN;

ALZHEIMER DISEASE; ARTICLE; CONFIDENCE INTERVAL; DATA EXTRACTION; ETHNICITY; GENE FREQUENCY; GENETIC SUSCEPTIBILITY; HUMAN; META ANALYSIS; PRIORITY JOURNAL; PUBLISHING; QUALITY CONTROL; RISK; SENSITIVITY ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ALZHEIMER DISEASE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; RISK; RISK FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84875380850     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2013.01.021     Document Type: Article

References (39)

1. Bertram L., Tanzi R.E. Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses. Nat. Rev. Neurosci. 2008, 9:768-778.
2. Brogan I.J., Khan N., Isaac K., Hutchinson J.A., Pravica V., Hutchinson I.V. Novel polymorphisms in the promoter and 5'UTR regions of the human vascular endothelial growth factor gene. Hum. Immunol. 1999, 60:1245-1249.
3. Brookmeyer R., Johnson E., Ziegler-Graham K., Arrighi H.M. Forecasting the global burden of Alzheimer's disease. Alzheimers Dement. 2007, 3:186-191.
4. Castellani R.J., Rolston R.K., Smith M.A. Alzheimer disease. Dis. Mon. 2010, 56:484.
5. Chapuis J., et al. Association study of the vascular endothelial growth factor gene with the risk of developing Alzheimer's disease. Neurobiol. Aging 2006, 27:1212-1215.
6. Chiappelli M., et al. VEGF gene and phenotype relation with Alzheimer's disease and mild cognitive impairment. Rejuvenation Res. 2006, 9:485-493.
7. De La Torre J. The vascular hypothesis of Alzheimer's disease: bench to bedside and beyond. Neurodegener. Dis. 2010, 7:116-121.
8. De la Torre J., Mussivand T. Can disturbed brain microcirculation cause Alzheimer's disease?. Neurol. Res. 1993, 15:146.
9. Del Bo R., et al. Vascular endothelial growth factor gene variability is associated with increased risk for AD. Ann. Neurol. 2005, 57:373-380.
10. Del Bo R., Ghezzi S., Scarpini E., Bresolin N., Comi G.P. VEGF genetic variability is associated with increased risk of developing Alzheimer's disease. J. Neurol. Sci. 2009, 283:66-68.
11. DerSimonian R., Laird N. Meta-analysis in clinical trials. Control. Clin. Trials 1986, 7:177-188.
12. Farkas E., Luiten P.G.M. Cerebral microvascular pathology in aging and Alzheimer's disease. Prog. Neurobiol. 2001, 64:575-611.
13. Hardy J. A hundred years of Alzheimer's disease research. Neuron 2006, 52:3-13.
14. Ioannidis J., Patsopoulos N.A., Evangelou E. Uncertainty in heterogeneity estimates in meta-analyses. BMJ 2007, 335:914-916.
15. Lafuente J.V., Ortuzar N., Bengoetxea H., Bulnes S., Argandoña E.G. Vascular endothelial growth factor and other angioglioneurins: key molecules in brain development and restoration. Int Rev Neurobiol. 2012, 102:317-346.
16. Lambrechts D., Carmeliet P. VEGF at the neurovascular interface: therapeutic implications for motor neuron disease. Biochim. Biophys. Acta Mol. Basis Dis. 2006, 1762:1109-1121.
17. Landgren S., et al. No association of VEGF polymorphims with Alzheimer's disease. Neruomol. Med. 2010, 12:224-228.
18. Mantel N., Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. The Challenge of Epidemiology: Issues and Selected Readings 2004, 1:533-553.
19. Mateo I., et al. Case-control study of vascular endothelial growth factor (VEGF) genetic variability in Alzheimer's disease. Neurosci. Lett. 2006, 401:171-173.
20. Mateo I., et al. Low serum VEGF levels are associated with Alzheimer's disease. Acta Neurol. Scand. 2007, 116:56-58.
21. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease. Neurology 1984, 34:939-944.
22. Qi H.P., Qu Z.Y., Duan S.R., Wei S.Q., Wen S.R., Bi S. IL-6-174G/C and -572 C/G polymorphisms and risk of Alzheimer's disease. PLoS One 2012, 7:e37858.
23. Reitz C., Brayne C., Mayeux R. Epidemiology of Alzheimer disease. Nat. Rev. Neurol. 2011, 7:137-152.
24. Richard F., Amouyel P. Genetic susceptibility factors for Alzheimer's disease. Eur. J. Pharmacol. 2001, 412:1-12.
25. Roses A.D. On the discovery of the genetic association of Apolipoprotein E genotypes and common late-onset Alzheimer disease. J. Alzheimer's Dis. 2006, 9:361-366.
26. Smach M.A., et al. -1154G/A and -2578C/A polymorphisms of the vascular endothelial growth factor gene in Tunisian Alzheimer patients in relation to [beta]-amyloid (1-42) and total tau protein. Neurosci. Lett. 2010, 472:139-142.
27. Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur. J. Epidemiol. 2010, 25:603-605.
28. Storkebaum E., Carmeliet P. VEGF: a critical player in neurodegeneration. J. Clin. Investig. 2004, 113:14-18.
29. Sun Y., et al. VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia. J. Clin. Investig. 2003, 111:1843-1852.
30. Tarkowski E., et al. Increased intrathecal levels of the angiogenic factors VEGF and TGF-β in Alzheimer's disease and vascular dementia. Neurobiol. Aging 2002, 23:237-243.
31. Thirumangalakudi L., Samany P.G., Owoso A., Wiskar B., Grammas P. Angiogenic proteins are expressed by brain blood vessels in Alzheimer's disease. J. Alzheimer's Dis. 2006, 10:111-118.
32. Tischer E., et al. The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J. Biol. Chem. 1991, 266:11947-11954.
33. Vagnucci A.H., Li W.W. Alzheimer's disease and angiogenesis. Lancet 2003, 361:605-608.
34. Viña J., Lloret A. Why women have more Alzheimer's disease than men: gender and mitochondrial toxicity of amyloid-β peptide. J. Alzheimer's Dis. 2010, 20:527-533.
35. Wang Y., et al. VEGF-overexpressing transgenic mice show enhanced post-ischemic neurogenesis and neuromigration. J. Neurosci. Res. 2007, 85:740-747.
36. Yuan Q., Zuo X., Jia J. Association between promoter polymorphisms of vascular endothelial growth factor gene and sporadic Alzheimer's disease among Northern Chinese Han. Neurosci. Lett. 2009, 457:133-136.
37. Zacchigna S., Lambrechts D., Carmeliet P. Neurovascular signalling defects in neurodegeneration. Nat. Rev. Neurosci. 2008, 9:169-181.
38. Zlokovic B.V. Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. Nat. Rev. Neurosci. 2011, 12:723-738.
39. Zlokovic B.V., Ghiso J., Mackic J.B., McComb J., Weiss M.H., Frangione B. Blood-brain barrier transport of circulating Alzheimer' s amyloid β. Biochem. Biophys. Res. Commun. 1993, 197:1034-1040.