Psychosocial stress and inflammation in cancer

Brain, Behavior, and Immunity

Volumn 30, Issue SUPPL., 2013, Pages

  Powell, N D ^a   Tarr, A J ^a   Sheridan, J F ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Cancer; Catecholamines; Glucocorticoids; IL 6; Immune dysregulation; Psychosocial stress

Indexed keywords

AUTACOID; CATECHOLAMINE; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUCOCORTICOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 6; PROTEIN C FOS; TUMOR NECROSIS FACTOR ALPHA;

ADRENERGIC SYSTEM; AMYGDALOID NUCLEUS; ANGIOGENESIS; CANCER INVASION; CELL INVASION; CELL MIGRATION; CENTRAL NERVOUS SYSTEM; CYTOTOXIC T LYMPHOCYTE; HIPPOCAMPUS; HORMONE RELEASE; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; INFLAMMATION; MENTAL STRESS; METASTASIS; NATURAL KILLER CELL; NEOPLASM; NEUROENDOCRINE SYSTEM; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; REVIEW; SOCIAL STRESS; STRIA TERMINALIS; TUMOR CELL; TUMOR GROWTH; TUMOR IMMUNITY; TUMOR MICROENVIRONMENT;

ANIMALS; CYTOKINES; GLUCOCORTICOIDS; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; IMMUNE SYSTEM; INFLAMMATION; NEOPLASMS; PITUITARY-ADRENAL SYSTEM; STRESS, PSYCHOLOGICAL;

EID: 84875372294     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2012.06.015     Document Type: Review

References (69)

1. Andersen B.L., Farrar W.B., Golden-Kreutz D., Kutz L.A., MacCallum R., Courtney M.E., Glaser R. Stress and immune responses after surgical treatment for regional breast cancer. J. Natl. Cancer Inst. 1998, 90:30-36.
2. Antonova L., Mueller C.R. Hydrocortisone down-regulates the tumor suppressor gene BRCA1 in mammary cells: a possible molecular link between stress and breast cancer. Genes Chromosomes Canc. 2008, 47:341-352.
3. Avitsur R., Stark J.L., Dhabhar F.S., Sheridan J.F. Social stress alters splenocyte phenotype and function. J. Neuroimmunol. 2002, 132:66-71.
4. Badino G.R., Novelli A., Girardi C., Di C.F. Evidence for functional beta-adrenoceptor subtypes in CG-5 breast cancer cell. Pharmacol. Res. 1996, 33:255-260.
5. Bailey M.T., Engler H., Powell N.D., Padgett D.A., Sheridan J.F. Repeated social defeat increases the bactericidal activity of splenic macrophages through a Toll-like receptor-dependent pathway. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 293:R1180-R1190.
6. Bailey M.T., Kierstein S., Sharma S., Spaits M., Kinsey S.G., Tliba O., Amrani Y., Sheridan J.F., Panettieri R.A., Haczku A. Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production. J. Immunol. 2009, 182:7888-7896.
7. Bailey M.T., Kinsey S.G., Padgett D.A., Sheridan J.F., Leblebicioglu B. Social stress enhances IL-1beta and TNF-alpha production by Porphyromonas gingivalis lipopolysaccharide-stimulated CD11b+ cells. Physiol. Behav. 2009, 98:351-358.
8. Bubenik J. MHC class I down-regulation: tumour escape from immune surveillance? (review). Int. J. Oncol. 2004, 25:487-491.
9. Carena I., Shamshiev A., Donda A., Colonna M., Libero G.D. Major histocompatibility complex class I molecules modulate activation threshold and early signaling of T cell antigen receptor-gamma/delta stimulated by nonpeptidic ligands. J. Exp. Med. 1997, 186:1769-1774.
10. Chung Y.C., Chang Y.F. Serum interleukin-6 levels reflect the disease status of colorectal cancer. J. Surg. Oncol. 2003, 83:222-226.
11. Curry J.M., Hanke M.L., Piper M.G., Bailey M.T., Bringardner B.D., Sheridan J.F., Marsh C.B. Social disruption induces lung inflammation. Brain Behav. Immun. 2010, 24:394-402.
12. DeMichele A., Martin A.M., Mick R., Gor P., Wray L., Klein-Cabral M., Athanasiadis G., Colligan T., Stadtmauer E., Weber B. Interleukin-6 -174G→C polymorphism is associated with improved outcome in high-risk breast cancer. Cancer Res. 2003, 63:8051-8056.
13. Dickinson R.E., Fegan K.S., Ren X., Hillier S.G., Duncan W.C. Glucocorticoid regulation of SLIT/ROBO tumour suppressor genes in the ovarian surface epithelium and ovarian cancer cells. PLoS One 2011, 6:e27792.
14. Dong-Newsom P., Powell N.D., Bailey M.T., Padgett D.A., Sheridan J.F. Repeated social stress enhances the innate immune response to a primary HSV-1 infection in the cornea and trigeminal ganglia of Balb/c mice. Brain Behav. Immun. 2010, 24:273-280.
15. Drell T.L., Joseph J., Lang K., Niggemann B., Zaenker K.S., Entschladen F. Effects of neurotransmitters on the chemokinesis and chemotaxis of MDA-MB-468 human breast carcinoma cells. Breast Cancer Res. Treat. 2003, 80:63-70.
16. Engler H., Bailey M.T., Engler A., Sheridan J.F. Effects of repeated social stress on leukocyte distribution in bone marrow, peripheral blood and spleen. J. Neuroimmunol. 2004, 148:106-115.
17. Engler H., Dawils L., Hoves S., Kurth S., Stevenson J.R., Schauenstein K., Stefanski V. Effects of social stress on blood leukocyte distribution: the role of alpha- and beta-adrenergic mechanisms. J. Neuroimmunol. 2004, 156:153-162.
18. Engler H., Engler A., Bailey M.T., Sheridan J.F. Tissue-specific alterations in the glucocorticoid sensitivity of immune cells following repeated social defeat in mice. J. Neuroimmunol. 2005, 163:110-119.
19. Felten D.L., Felten S.Y., Carlson S.L., Olschowka J.A., Livnat S. Noradrenergic and peptidergic innervation of lymphoid tissue. J. Immunol. 1985, 135:755s-765s.
20. Glaser R., Pearl D.K., Kiecolt-Glaser J.K., Malarkey W.B. Plasma cortisol levels and reactivation of latent Epstein-Barr virus in response to examination stress. Psychoneuroendocrinology 1994, 19:765-772.
21. Glaser R., Kiecolt-Glaser J.K. Stress-induced immune dysfunction: implications for health. Nat. Rev. Immunol. 2005, 5:243-251.
22. Gouin J.P., Glaser R., Malarkey W.B., Beversdorf D., Kiecolt-Glaser J. Chronic stress, daily stressors, and circulating inflammatory markers. Health Psychol 2012, 31(2):264-268. Mar.
23. Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
24. Hanke T., Takizawa H., McMahon C.W., Busch D.H., Pamer E.G., Miller J.D., Altman J.D., Liu Y., Cado D., Lemonnier F.A., Bjorkman P.J., Raulet D.H. Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. Immunity 1999, 11:67-77.
25. Hunzeker J., Padgett D.A., Sheridan P.A., Dhabhar F.S., Sheridan J.F. Modulation of natural killer cell activity by restraint stress during an influenza A/PR8 infection in mice. Brain Behav. Immun. 2004, 18:526-535.
26. Jean D., Bar-Eli M. Regulation of tumor growth and metastasis of human melanoma by the CREB transcription factor family. Mol. Cell Biochem. 2000, 212:19-28.
27. Kinsey S.G., Bailey M.T., Sheridan J.F., Padgett D.A., Avitsur R. Repeated social defeat causes increased anxiety-like behavior and alters splenocyte function in C57BL/6 and CD-1 mice. Brain Behav. Immun. 2007, 21:458-466.
28. Kossakowska A.E., Edwards D.R., Prusinkiewicz C., Zhang M.C., Guo D., Urbanski S.J., Grogan T., Marquez L.A., Janowska-Wieczorek A. Interleukin-6 regulation of matrix metalloproteinase (MMP-2 and MMP-9) and tissue inhibitor of metalloproteinase (TIMP-1) expression in malignant non-Hodgkin's lymphomas. Blood 1999, 94:2080-2089.
29. Kradin R., Rodberg G., Zhao L.H., Leary C. Epinephrine yields translocation of lymphocytes to the lung. Exp. Mol. Pathol. 2001, 70:1-6.
30. Lang K., Drell T.L., Lindecke A., Niggemann B., Kaltschmidt C., Zaenker K.S., Entschladen F. Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs. Int. J. Cancer 2004, 112:231-238.
31. Levy S., Herberman R., Lippman M., d'Angelo T. Correlation of stress factors with sustained depression of natural killer cell activity and predicted prognosis in patients with breast cancer. J. Clin. Oncol. 1987, 5:348-353.
32. Lillberg K., Verkasalo P.K., Kaprio J., Teppo L., Helenius H., Koskenvuo M. Stressful life events and risk of breast cancer in 10,808 women: a cohort study. Am. J. Epidemiol. 2003, 157:415-423.
33. Madden K.S., Sanders V.M., Felten D.L. Catecholamine influences and sympathetic neural modulation of immune responsiveness. Annu. Rev. Pharmacol. Toxicol. 1995, 35:417-448.
34. Masur K., Niggemann B., Zanker K.S., Entschladen F. Norepinephrine-induced migration of SW 480 colon carcinoma cells is inhibited by beta-blockers. Cancer Res. 2001, 61:2866-2869.
35. Mays J.W., Bailey M.T., Hunzeker J.T., Powell N.D., Papenfuss T., Karlsson E.A., Padgett D.A., Sheridan J.F. Influenza virus-specific immunological memory is enhanced by repeated social defeat. J. Immunol. 2010, 184:2014-2025.
36. Mays J.W., Powell N.D., Hunzeker J.T., Hanke M.L., Bailey M.T., Sheridan J.F. Stress and the anti-influenza immune response: Repeated social defeat augments clonal expansion of CD8(+)T cells during primary influenza A viral infection. J. Neuroimmunol. 2012, 243:34-42.
37. Miller G.E., Chen E., Sze J., Marin T., Arevalo J.M., Doll R., Ma R., Cole S.W. A functional genomic fingerprint of chronic stress in humans: blunted glucocorticoid and increased NF-kappaB signaling. Biol. Psychiatry 2008, 64:266-272.
38. Mundy-Bosse B.L., Thornton L.M., Yang H.C., Andersen B.L., Carson W.E. Psychological stress is associated with altered levels of myeloid-derived suppressor cells in breast cancer patients. Cell Immunol. 2011, 270:80-87.
39. Ostrand-Rosenberg S., Sinha P. Myeloid-derived suppressor cells: linking inflammation and cancer. J. Immunol. 2009, 182:4499-4506.
40. Padgett D.A., Glaser R. How stress influences the immune response?. Trends Immunol. 2003, 24:444-448.
41. Palermo-Neto J., de Oliveira M.C., Robespierre de S.W. Effects of physical and psychological stressors on behavior, macrophage activity, and Ehrlich tumor growth. Brain Behav. Immun. 2003, 17:43-54.
42. Palm D., Lang K., Niggemann B., Drell T.L., Masur K., Zaenker K.S., Entschladen F. The norepinephrine-driven metastasis development of PC-3 human prostate cancer cells in BALB/c nude mice is inhibited by beta-blockers. Int. J. Cancer 2006, 118:2744-2749.
43. Pierce B.L., Ballard-Barbash R., Bernstein L., Baumgartner R.N., Neuhouser M.L., Wener M.H., Baumgartner K.B., Gilliland F.D., Sorensen B.E., McTiernan A., Ulrich C.M. Elevated biomarkers of inflammation are associated with reduced survival among breast cancer patients. J. Clin. Oncol. 2009, 27:3437-3444.
44. Powell N.D., Bailey M.T., Mays J.W., Stiner-Jones L.M., Hanke M.L., Padgett D.A., Sheridan J.F. Repeated social defeat activates dendritic cells and enhances toll-like receptor dependent cytokine secretion. Brain Behav. Immun. 2009, 23:225-231.
45. Powell N.D., Mays J.W., Bailey M.T., Hanke M.L., Sheridan J.F. Immunogenic dendritic cells primed by social defeat enhance adaptive immunity to influenza A virus. Brain Behav. Immun. 2011, 25:46-52.
46. Price M.A., Tennant C.C., Butow P.N., Smith R.C., Kennedy S.J., Kossoff M.B., Dunn S.M. The role of psychosocial factors in the development of breast carcinoma: part II. life event stressors, social support, defense style, and emotional control and their interactions. Cancer 2001, 91:686-697.
47. Reilly F.D., McCuskey P.A., Miller M.L., McCuskey R.S., Meineke H.A. Innervation of the periarteriolar lymphatic sheath of the spleen. Tissue Cell 1979, 11:121-126.
48. Salgado R., Junius S., Benoy I., Van D.P., Vermeulen P., Van M.E., Huget P., Dirix L.Y. Circulating interleukin-6 predicts survival in patients with metastatic breast cancer. Int. J. Cancer 2003, 103:642-646.
49. Sanders V.M. The role of adrenoceptor-mediated signals in the modulation of lymphocyte function. Adv. Neuroimmunol. 1995, 5:283-298.
50. Sastry K.S., Karpova Y., Prokopovich S., Smith A.J., Essau B., Gersappe A., Carson J.P., Weber M.J., Register T.C., Chen Y.Q., Penn R.B., Kulik G. Epinephrine protects cancer cells from apoptosis via activation of cAMP-dependent protein kinase and BAD phosphorylation. J. Biol. Chem. 2007, 282:14094-14100.
51. Saul A.N., Oberyszyn T.M., Daugherty C., Kusewitt D., Jones S., Jewell S., Malarkey W.B., Lehman A., Lemeshow S., Dhabhar F.S. Chronic stress and susceptibility to skin cancer. J. Natl. Cancer Inst. 2005, 97:1760-1767.
52. Schedlowski M., Falk A., Rohne A., Wagner T.O., Jacobs R., Tewes U., Schmidt R.E. Catecholamines induce alterations of distribution and activity of human natural killer (NK) cells. J. Clin. Immunol. 1993, 13:344-351.
53. Sieber W.J., Rodin J., Larson L., Ortega S., Cummings N., Levy S., Whiteside T., Herberman R. Modulation of human natural killer cell activity by exposure to uncontrollable stress. Brain Behav. Immun. 1992, 6:141-156.
54. Sloan E.K., Priceman S.J., Cox B.F., Yu S., Pimentel M.A., Tangkanangnukul V., Arevalo J.M., Morizono K., Karanikolas B.D., Wu L., Sood A.K., Cole S.W. The sympathetic nervous system induces a metastatic switch in primary breast cancer. Cancer Res. 2010, 70:7042-7052.
55. Snoussi K., Strosberg A.D., Bouaouina N., Ben A.S., Chouchane L. Genetic variation in pro-inflammatory cytokines (interleukin-1beta, interleukin-1alpha and interleukin-6) associated with the aggressive forms, survival, and relapse prediction of breast carcinoma. Eur. Cytokine Netw. 2005, 16:253-260.
56. Sood A.K., Bhatty R., Kamat A.A., Landen C.N., Han L., Thaker P.H., Li Y., Gershenson D.M., Lutgendorf S., Cole S.W. Stress hormone-mediated invasion of ovarian cancer cells. Clin. Cancer Res. 2006, 12:369-375.
57. Spiegel D., Giese-Davis J. Depression and cancer: mechanisms and disease progression. Biol. Psychiatry 2003, 54:269-282.
58. Stark J.L., Avitsur R., Hunzeker J., Padgett D.A., Sheridan J.F. Interleukin-6 and the development of social disruption-induced glucocorticoid resistance. J. Neuroimmunol. 2002, 124:9-15.
59. Steplewski Z., Vogel W.H., Ehya H., Poropatich C., Smith J.M. Effects of restraint stress on inoculated tumor growth and immune response in rats. Cancer Res. 1985, 45:5128-5133.
60. Tan K.S., Nackley A.G., Satterfield K., Maixner W., Diatchenko L., Flood P.M. Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kappaB-independent mechanisms. Cell Signal 2007, 19:251-260.
61. Tomozawa Y., Yabuuchi K., Inoue T., Satoh M. Participation of cAMP and cAMP-dependent protein kinase in beta-adrenoceptor-mediated interleukin-1 beta mRNA induction in cultured microglia. Neurosci. Res. 1995, 22:399-409.
62. Tseng R.J., Padgett D.A., Dhabhar F.S., Engler H., Sheridan J.F. Stress-induced modulation of NK activity during influenza viral infection: role of glucocorticoids and opioids. Brain Behav. Immun. 2005, 19:153-164.
63. Vahlne G., Lindholm K., Meier A., Wickstrom S., Lakshmikanth T., Brennan F., Wilken M., Nielsen R., Romagne F., Wagtmann N.R., Karre K., Johansson M.H. In vivo tumor cell rejection induced by NK cell inhibitory receptor blockade: maintained tolerance to normal cells even in the presence of IL-2. Eur. J. Immunol. 2010, 40:813-823.
64. Williams J.M., Peterson R.G., Shea P.A., Schmedtje J.F., Bauer D.C., Felten D.L. Sympathetic innervation of murine thymus and spleen: evidence for a functional link between the nervous and immune systems. Brain Res. Bull. 1981, 6:83-94.
65. Wohleb E.S., Hanke M.L., Corona A.W., Powell N.D., Stiner L.M., Bailey M.T., Nelson R.J., Godbout J.P., Sheridan J.F. Beta-Adrenergic receptor antagonism prevents anxiety-like behavior and microglial reactivity induced by repeated social defeat. J. Neurosci. 2011, 31:6277-6288.
66. Wu W., Chaudhuri S., Brickley D.R., Pang D., Karrison T., Conzen S.D. Microarray analysis reveals glucocorticoid-regulated survival genes that are associated with inhibition of apoptosis in breast epithelial cells. Cancer Res. 2004, 64:1757-1764.
67. Xia C., Meng Q., Liu L.Z., Rojanasakul Y., Wang X.R., Jiang B.H. Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor. Cancer Res. 2007, 67:10823-10830.
68. Yang E.V., Sood A.K., Chen M., Li Y., Eubank T.D., Marsh C.B., Jewell S., Flavahan N.A., Morrison C., Yeh P.E., Lemeshow S., Glaser R. Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells. Cancer Res. 2006, 66:10357-10364.
69. Yu W.G., Yamamoto N., Takenaka H., Mu J., Tai X.G., Zou J.P., Ogawa M., Tsutsui T., Wijesuriya R., Yoshida R., Herrmann S., Fujiwara H., Hamaoka T. Molecular mechanisms underlying IFN-gamma-mediated tumor growth inhibition induced during tumor immunotherapy with rIL-12. Int. Immunol. 1996, 8:855-865.