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Volumn 331, Issue 2, 2013, Pages 147-153

Platelet factor-4 (CXCL4/PF-4): An angiostatic chemokine for cancer therapy

Author keywords

Angiogenesis; Cancer therapy; Platelet factor 4

Indexed keywords

CHEMOKINE RECEPTOR CXCR3; CHEMOKINE RECEPTOR CXCR3B; FIBROBLAST GROWTH FACTOR 2; INTEGRIN; INTERLEUKIN 8; THROMBOCYTE FACTOR 4; UNCLASSIFIED DRUG; VASCULOTROPIN 121; VASCULOTROPIN 165;

EID: 84875370042     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.01.006     Document Type: Review
Times cited : (51)

References (69)
  • 1
    • 34548041028 scopus 로고
    • Differentiation of certain platelet factors related to blood coagulation
    • Deutsch E., Johnson S.A., Seegers W.H. Differentiation of certain platelet factors related to blood coagulation. Circ. Res. 1955, 3:110-115.
    • (1955) Circ. Res. , vol.3 , pp. 110-115
    • Deutsch, E.1    Johnson, S.A.2    Seegers, W.H.3
  • 2
    • 15044355644 scopus 로고    scopus 로고
    • Platelet factor 4: a chemokine enigma
    • Slungaard A. Platelet factor 4: a chemokine enigma. Int. J. Biochem. Cell Biol. 2005, 37:1162-1167.
    • (2005) Int. J. Biochem. Cell Biol. , vol.37 , pp. 1162-1167
    • Slungaard, A.1
  • 4
    • 0025767622 scopus 로고
    • Inhibition of tumor growth in mice by an analogue of platelet factor 4 that lacks affinity for heparin and retains potent angiostatic activity
    • Maione T.E., Gray G.S., Hunt A.J., Sharpe R.J. Inhibition of tumor growth in mice by an analogue of platelet factor 4 that lacks affinity for heparin and retains potent angiostatic activity. Cancer Res. 1991, 51:2077-2083.
    • (1991) Cancer Res. , vol.51 , pp. 2077-2083
    • Maione, T.E.1    Gray, G.S.2    Hunt, A.J.3    Sharpe, R.J.4
  • 5
    • 0028921520 scopus 로고
    • Inhibition of development of murine melanoma lung metastases by systemic administration of recombinant platelet factor 4
    • Kolber D.L., Knisely T.L., Maione T.E. Inhibition of development of murine melanoma lung metastases by systemic administration of recombinant platelet factor 4. J. Natl. Cancer Inst. 1995, 87:304-309.
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 304-309
    • Kolber, D.L.1    Knisely, T.L.2    Maione, T.E.3
  • 6
    • 0025322835 scopus 로고
    • Structural and functional comparison of the genes for human platelet factor 4 and PF4alt
    • Eisman R., Surrey S., Ramachandran B., Schwartz E., Poncz M. Structural and functional comparison of the genes for human platelet factor 4 and PF4alt. Blood 1990, 76:336-344.
    • (1990) Blood , vol.76 , pp. 336-344
    • Eisman, R.1    Surrey, S.2    Ramachandran, B.3    Schwartz, E.4    Poncz, M.5
  • 7
    • 0023131421 scopus 로고
    • Cloning and characterization of platelet factor 4 cDNA derived from a human erythroleukemic cell line
    • Poncz M., Surrey S., LaRocco P., Weiss M.J., Rappaport E.F., Conway T.M., Schwartz E. Cloning and characterization of platelet factor 4 cDNA derived from a human erythroleukemic cell line. Blood 1987, 69:219-223.
    • (1987) Blood , vol.69 , pp. 219-223
    • Poncz, M.1    Surrey, S.2    LaRocco, P.3    Weiss, M.J.4    Rappaport, E.F.5    Conway, T.M.6    Schwartz, E.7
  • 8
    • 0026684989 scopus 로고
    • Genes for beta-thromboglobulin and platelet factor 4 are closely linked and form part of a cluster of related genes on chromosome 4
    • Tunnacliffe A., Majumdar S., Yan B., Poncz M. Genes for beta-thromboglobulin and platelet factor 4 are closely linked and form part of a cluster of related genes on chromosome 4. Blood 1992, 79:2896-2900.
    • (1992) Blood , vol.79 , pp. 2896-2900
    • Tunnacliffe, A.1    Majumdar, S.2    Yan, B.3    Poncz, M.4
  • 11
    • 0019426232 scopus 로고
    • Human megakaryocytes. II. Expression of platelet proteins in early marrow megakaryocytes
    • Rabellino E.M., Levene R.B., Leung L.L., Nachman R.L. Human megakaryocytes. II. Expression of platelet proteins in early marrow megakaryocytes. J. Exp. Med. 1981, 154:88-100.
    • (1981) J. Exp. Med. , vol.154 , pp. 88-100
    • Rabellino, E.M.1    Levene, R.B.2    Leung, L.L.3    Nachman, R.L.4
  • 13
    • 0019310643 scopus 로고
    • Human platelet factor 4 and tissue mast cells
    • McLaren K.M., Holloway L., Pepper D.S. Human platelet factor 4 and tissue mast cells. Thromb. Res. 1980, 19:293-297.
    • (1980) Thromb. Res. , vol.19 , pp. 293-297
    • McLaren, K.M.1    Holloway, L.2    Pepper, D.S.3
  • 14
    • 24044540392 scopus 로고    scopus 로고
    • Evidence for a granule targeting sequence within platelet factor 4
    • El Golli N., Issertial O., Rosa J.P., Briquet-Laugier V. Evidence for a granule targeting sequence within platelet factor 4. J. Biol. Chem. 2005, 280:30329-30335.
    • (2005) J. Biol. Chem. , vol.280 , pp. 30329-30335
    • El Golli, N.1    Issertial, O.2    Rosa, J.P.3    Briquet-Laugier, V.4
  • 15
    • 0014693914 scopus 로고
    • Platelet factor 4 and adenosine diphosphate release during human platelet aggregation
    • Niewiarowski S., Thomas D.P. Platelet factor 4 and adenosine diphosphate release during human platelet aggregation. Nature 1969, 222:1269-1270.
    • (1969) Nature , vol.222 , pp. 1269-1270
    • Niewiarowski, S.1    Thomas, D.P.2
  • 16
    • 0018740870 scopus 로고
    • Platelet alpha-granule proteins: studies on release and subcellular localization
    • Kaplan K.L., Broekman M.J., Chernoff A., Lesznik G.R., Drillings M. Platelet alpha-granule proteins: studies on release and subcellular localization. Blood 1979, 53:604-618.
    • (1979) Blood , vol.53 , pp. 604-618
    • Kaplan, K.L.1    Broekman, M.J.2    Chernoff, A.3    Lesznik, G.R.4    Drillings, M.5
  • 17
    • 22144494616 scopus 로고    scopus 로고
    • Regulated expression of platelet factor 4 in human monocytes-role of PARs as a quantitatively important monocyte activation pathway
    • Schaffner A., Rhyn P., Schoedon G., Schaer D.J. Regulated expression of platelet factor 4 in human monocytes-role of PARs as a quantitatively important monocyte activation pathway. J. Leukocyte Biol. 2005, 78:202-209.
    • (2005) J. Leukocyte Biol. , vol.78 , pp. 202-209
    • Schaffner, A.1    Rhyn, P.2    Schoedon, G.3    Schaer, D.J.4
  • 19
    • 0025944268 scopus 로고
    • Platelet factor 4: production, structure, and physiologic and immunologic action
    • Zucker M.B., Katz I.R. Platelet factor 4: production, structure, and physiologic and immunologic action. Proc. Soc. Exp. Biol. Med. 1991, 198:693-702.
    • (1991) Proc. Soc. Exp. Biol. Med. , vol.198 , pp. 693-702
    • Zucker, M.B.1    Katz, I.R.2
  • 20
    • 0025248229 scopus 로고
    • Platelet factor 4 inhibits human megakaryocytopoiesis in vitro
    • Han Z.C., Sensebe L., Abgrall J.F., Briere J. Platelet factor 4 inhibits human megakaryocytopoiesis in vitro. Blood 1990, 75:1234-1239.
    • (1990) Blood , vol.75 , pp. 1234-1239
    • Han, Z.C.1    Sensebe, L.2    Abgrall, J.F.3    Briere, J.4
  • 21
    • 34548008184 scopus 로고    scopus 로고
    • Platelet factor 4 is a negative autocrine in vivo regulator of megakaryopoiesis: clinical and therapeutic implications
    • Lambert M.P., Rauova L., Bailey M., Sola-Visner M.C., Kowalska M.A., Poncz M. Platelet factor 4 is a negative autocrine in vivo regulator of megakaryopoiesis: clinical and therapeutic implications. Blood 2007, 110:1153-1160.
    • (2007) Blood , vol.110 , pp. 1153-1160
    • Lambert, M.P.1    Rauova, L.2    Bailey, M.3    Sola-Visner, M.C.4    Kowalska, M.A.5    Poncz, M.6
  • 22
    • 0038454623 scopus 로고    scopus 로고
    • Platelet factor 4 promotes adhesion of hematopoietic progenitor cells and binds IL-8: novel mechanisms for modulation of hematopoiesis
    • Dudek A.Z., Nesmelova I., Mayo K., Verfaillie C.M., Pitchford S., Slungaard A. Platelet factor 4 promotes adhesion of hematopoietic progenitor cells and binds IL-8: novel mechanisms for modulation of hematopoiesis. Blood 2003, 101:4687-4694.
    • (2003) Blood , vol.101 , pp. 4687-4694
    • Dudek, A.Z.1    Nesmelova, I.2    Mayo, K.3    Verfaillie, C.M.4    Pitchford, S.5    Slungaard, A.6
  • 23
    • 0019798009 scopus 로고
    • Dansyl (5-dimethylaminonaphthalene-1-sulphonyl)-heparin binds antithrombin III and platelet factor 4 at separate sites
    • Piepkorn M.W. Dansyl (5-dimethylaminonaphthalene-1-sulphonyl)-heparin binds antithrombin III and platelet factor 4 at separate sites. Biochem. J. 1981, 196:649-651.
    • (1981) Biochem. J. , vol.196 , pp. 649-651
    • Piepkorn, M.W.1
  • 24
    • 0019123712 scopus 로고
    • Inhibition of contact activation by platelet factor 4
    • Scully M.F., Weerasinghe K., Kakkar V.V. Inhibition of contact activation by platelet factor 4. Thromb. Res. 1980, 20:461-466.
    • (1980) Thromb. Res. , vol.20 , pp. 461-466
    • Scully, M.F.1    Weerasinghe, K.2    Kakkar, V.V.3
  • 25
    • 0023706578 scopus 로고
    • Inhibition of the activation of Hageman factor (factor XII) by platelet factor 4
    • Dumenco L.L., Everson B., Culp L.A., Ratnoff O.D. Inhibition of the activation of Hageman factor (factor XII) by platelet factor 4. J. Lab. Clin. Med. 1988, 112:394-400.
    • (1988) J. Lab. Clin. Med. , vol.112 , pp. 394-400
    • Dumenco, L.L.1    Everson, B.2    Culp, L.A.3    Ratnoff, O.D.4
  • 27
    • 0022627573 scopus 로고
    • In vitro effects of platelet factor 4 on normal human neutrophil functions
    • Bebawy S.T., Gorka J., Hyers T.M., Webster R.O. In vitro effects of platelet factor 4 on normal human neutrophil functions. J. Leukocyte Biol. 1986, 39:423-434.
    • (1986) J. Leukocyte Biol. , vol.39 , pp. 423-434
    • Bebawy, S.T.1    Gorka, J.2    Hyers, T.M.3    Webster, R.O.4
  • 29
    • 33644772132 scopus 로고    scopus 로고
    • Mast cells and neutrophils proteolytically activate chemokine precursor CTAP-III and are subject to counterregulation by PF-4 through inhibition of chymase and cathepsin G
    • Schiemann F., Grimm T.A., Hoch J., Gross R., Lindner B., Petersen F., Bulfone-Paus S., Brandt E. Mast cells and neutrophils proteolytically activate chemokine precursor CTAP-III and are subject to counterregulation by PF-4 through inhibition of chymase and cathepsin G. Blood 2006, 107:2234-2242.
    • (2006) Blood , vol.107 , pp. 2234-2242
    • Schiemann, F.1    Grimm, T.A.2    Hoch, J.3    Gross, R.4    Lindner, B.5    Petersen, F.6    Bulfone-Paus, S.7    Brandt, E.8
  • 31
    • 9444249866 scopus 로고    scopus 로고
    • Platelet factor 4 in conjunction with IL-4 directs differentiation of human monocytes into specialized antigen-presenting cells
    • Fricke I., Mitchell D., Petersen F., Bohle A., Bulfone-Paus S., Brandau S. Platelet factor 4 in conjunction with IL-4 directs differentiation of human monocytes into specialized antigen-presenting cells. Faseb. J. 2004, 18:1588-1590.
    • (2004) Faseb. J. , vol.18 , pp. 1588-1590
    • Fricke, I.1    Mitchell, D.2    Petersen, F.3    Bohle, A.4    Bulfone-Paus, S.5    Brandau, S.6
  • 32
    • 0043025261 scopus 로고    scopus 로고
    • Effect of CXC chemokine platelet factor 4 on differentiation and function of monocyte-derived dendritic cells
    • Xia C.Q., Kao K.J. Effect of CXC chemokine platelet factor 4 on differentiation and function of monocyte-derived dendritic cells. Int. Immunol. 2003, 15:1007-1015.
    • (2003) Int. Immunol. , vol.15 , pp. 1007-1015
    • Xia, C.Q.1    Kao, K.J.2
  • 33
    • 3242799551 scopus 로고    scopus 로고
    • Platelet factor 4/CXCL4 induces phagocytosis and the generation of reactive oxygen metabolites in mononuclear phagocytes independently of Gi protein activation or intracellular calcium transients
    • Pervushina O., Scheuerer B., Reiling N., Behnke L., Schroder J.M., Kasper B., Brandt E., Bulfone-Paus S., Petersen F. Platelet factor 4/CXCL4 induces phagocytosis and the generation of reactive oxygen metabolites in mononuclear phagocytes independently of Gi protein activation or intracellular calcium transients. J. Immunol. 2004, 173:2060-2067.
    • (2004) J. Immunol. , vol.173 , pp. 2060-2067
    • Pervushina, O.1    Scheuerer, B.2    Reiling, N.3    Behnke, L.4    Schroder, J.M.5    Kasper, B.6    Brandt, E.7    Bulfone-Paus, S.8    Petersen, F.9
  • 35
    • 0036745072 scopus 로고    scopus 로고
    • Platelet factor 4 induces human natural killer cells to synthesize and release interleukin-8
    • Marti F., Bertran E., Llucia M., Villen E., Peiro M., Garcia J., Rueda F. Platelet factor 4 induces human natural killer cells to synthesize and release interleukin-8. J. Leukocyte Biol. 2002, 72:590-597.
    • (2002) J. Leukocyte Biol. , vol.72 , pp. 590-597
    • Marti, F.1    Bertran, E.2    Llucia, M.3    Villen, E.4    Peiro, M.5    Garcia, J.6    Rueda, F.7
  • 37
    • 14044273650 scopus 로고    scopus 로고
    • Platelet factor 4 differentially modulates CD4+CD25+ (regulatory) versus CD4+CD25-(nonregulatory) T cells
    • Liu C.Y., Battaglia M., Lee S.H., Sun Q.H., Aster R.H., Visentin G.P. Platelet factor 4 differentially modulates CD4+CD25+ (regulatory) versus CD4+CD25-(nonregulatory) T cells. J. Immunol. 2005, 174:2680-2686.
    • (2005) J. Immunol. , vol.174 , pp. 2680-2686
    • Liu, C.Y.1    Battaglia, M.2    Lee, S.H.3    Sun, Q.H.4    Aster, R.H.5    Visentin, G.P.6
  • 40
    • 0025268022 scopus 로고
    • Growth inhibition of murine melanoma and human colon carcinoma by recombinant human platelet factor 4
    • Sharpe R.J., Byers H.R., Scott C.F., Bauer S.I., Maione T.E. Growth inhibition of murine melanoma and human colon carcinoma by recombinant human platelet factor 4. J. Natl. Cancer Inst. 1990, 82:848-853.
    • (1990) J. Natl. Cancer Inst. , vol.82 , pp. 848-853
    • Sharpe, R.J.1    Byers, H.R.2    Scott, C.F.3    Bauer, S.I.4    Maione, T.E.5
  • 41
    • 0028276825 scopus 로고
    • Platelet factor 4 modulates the mitogenic activity of basic fibroblast growth factor
    • Watson J.B., Getzler S.B., Mosher D.F. Platelet factor 4 modulates the mitogenic activity of basic fibroblast growth factor. J. Clin. Invest. 1994, 94:261-268.
    • (1994) J. Clin. Invest. , vol.94 , pp. 261-268
    • Watson, J.B.1    Getzler, S.B.2    Mosher, D.F.3
  • 43
    • 2642708372 scopus 로고    scopus 로고
    • Platelet factor 4 modulates fibroblast growth factor 2 (FGF-2) activity and inhibits FGF-2 dimerization
    • Perollet C., Han Z.C., Savona C., Caen J.P., Bikfalvi A. Platelet factor 4 modulates fibroblast growth factor 2 (FGF-2) activity and inhibits FGF-2 dimerization. Blood 1998, 91:3289-3299.
    • (1998) Blood , vol.91 , pp. 3289-3299
    • Perollet, C.1    Han, Z.C.2    Savona, C.3    Caen, J.P.4    Bikfalvi, A.5
  • 44
    • 4143051554 scopus 로고    scopus 로고
    • Recent developments in the inhibition of angiogenesis: examples from studies on platelet factor-4 and the VEGF/VEGFR system
    • Bikfalvi A. Recent developments in the inhibition of angiogenesis: examples from studies on platelet factor-4 and the VEGF/VEGFR system. Biochem. Pharmacol. 2004, 68:1017-1021.
    • (2004) Biochem. Pharmacol. , vol.68 , pp. 1017-1021
    • Bikfalvi, A.1
  • 45
    • 0036789313 scopus 로고    scopus 로고
    • The role of fibroblast growth factors in vascular development
    • Javerzat S., Auguste P., Bikfalvi A. The role of fibroblast growth factors in vascular development. Trends Mol. Med. 2002, 8:483-489.
    • (2002) Trends Mol. Med. , vol.8 , pp. 483-489
    • Javerzat, S.1    Auguste, P.2    Bikfalvi, A.3
  • 46
    • 0017154001 scopus 로고
    • Purification and binding properties of human platelet factor four
    • Handin R.I., Cohen H.J. Purification and binding properties of human platelet factor four. J. Biol. Chem. 1976, 251:4273-4282.
    • (1976) J. Biol. Chem. , vol.251 , pp. 4273-4282
    • Handin, R.I.1    Cohen, H.J.2
  • 47
    • 0036839196 scopus 로고    scopus 로고
    • Platelet factor 4 inhibits FGF2-induced endothelial cell proliferation via the extracellular signal-regulated kinase pathway but not by the phosphatidylinositol 3-kinase pathway
    • Sulpice E., Bryckaert M., Lacour J., Contreres J.O., Tobelem G. Platelet factor 4 inhibits FGF2-induced endothelial cell proliferation via the extracellular signal-regulated kinase pathway but not by the phosphatidylinositol 3-kinase pathway. Blood 2002, 100:3087-3094.
    • (2002) Blood , vol.100 , pp. 3087-3094
    • Sulpice, E.1    Bryckaert, M.2    Lacour, J.3    Contreres, J.O.4    Tobelem, G.5
  • 49
    • 78149479992 scopus 로고    scopus 로고
    • Interaction of PF4 (CXCL4) with the vasculature: a role in atherosclerosis and angiogenesis
    • Aidoudi S., Bikfalvi A. Interaction of PF4 (CXCL4) with the vasculature: a role in atherosclerosis and angiogenesis. Thromb. Haemost. 2010, 104:941-948.
    • (2010) Thromb. Haemost. , vol.104 , pp. 941-948
    • Aidoudi, S.1    Bikfalvi, A.2
  • 50
    • 0027944881 scopus 로고
    • Inhibition of endothelial cell proliferation by platelet factor-4 involves a unique action on S phase progression
    • Gupta S.K., Singh J.P. Inhibition of endothelial cell proliferation by platelet factor-4 involves a unique action on S phase progression. J. Cell Biol. 1994, 127:1121-1127.
    • (1994) J. Cell Biol. , vol.127 , pp. 1121-1127
    • Gupta, S.K.1    Singh, J.P.2
  • 51
    • 0032910176 scopus 로고    scopus 로고
    • Inhibition of human umbilical vein endothelial cell proliferation by the CXC chemokine, platelet factor 4 (PF4), is associated with impaired downregulation of p21(Cip1/WAF1)
    • Gentilini G., Kirschbaum N.E., Augustine J.A., Aster R.H., Visentin G.P. Inhibition of human umbilical vein endothelial cell proliferation by the CXC chemokine, platelet factor 4 (PF4), is associated with impaired downregulation of p21(Cip1/WAF1). Blood 1999, 93:25-33.
    • (1999) Blood , vol.93 , pp. 25-33
    • Gentilini, G.1    Kirschbaum, N.E.2    Augustine, J.A.3    Aster, R.H.4    Visentin, G.P.5
  • 53
    • 0030937456 scopus 로고    scopus 로고
    • Viral vector-mediated transduction of a modified platelet factor 4 cDNA inhibits angiogenesis and tumor growth
    • Tanaka T., Manome Y., Wen P., Kufe D.W., Fine H.A. Viral vector-mediated transduction of a modified platelet factor 4 cDNA inhibits angiogenesis and tumor growth. Nat. Med. 1997, 3:437-442.
    • (1997) Nat. Med. , vol.3 , pp. 437-442
    • Tanaka, T.1    Manome, Y.2    Wen, P.3    Kufe, D.W.4    Fine, H.A.5
  • 54
    • 77953010693 scopus 로고    scopus 로고
    • Micronutrients attenuate progression of prostate cancer by elevating the endogenous inhibitor of angiogenesis, platelet factor-4
    • Cervi D., Pak B., Venier N.A., Sugar L.M., Nam R.K., Fleshner N.E., Klotz L.H., Venkateswaran V. Micronutrients attenuate progression of prostate cancer by elevating the endogenous inhibitor of angiogenesis, platelet factor-4. BMC Cancer 2010, 10:258.
    • (2010) BMC Cancer , vol.10 , pp. 258
    • Cervi, D.1    Pak, B.2    Venier, N.A.3    Sugar, L.M.4    Nam, R.K.5    Fleshner, N.E.6    Klotz, L.H.7    Venkateswaran, V.8
  • 55
    • 0029098320 scopus 로고
    • A potent inhibitor of endothelial cell proliferation is generated by proteolytic cleavage of the chemokine platelet factor 4
    • Gupta S.K., Hassel T., Singh J.P. A potent inhibitor of endothelial cell proliferation is generated by proteolytic cleavage of the chemokine platelet factor 4. Proc. Natl. Acad. Sci. USA 1995, 92:7799-7803.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7799-7803
    • Gupta, S.K.1    Hassel, T.2    Singh, J.P.3
  • 56
    • 79959223711 scopus 로고    scopus 로고
    • Platelet factor-4 and its p17-70 peptide inhibit myeloma proliferation and angiogenesis in vivo
    • Yang L., Du J., Hou J., Jiang H., Zou J. Platelet factor-4 and its p17-70 peptide inhibit myeloma proliferation and angiogenesis in vivo. BMC Cancer 2011, 11:261.
    • (2011) BMC Cancer , vol.11 , pp. 261
    • Yang, L.1    Du, J.2    Hou, J.3    Jiang, H.4    Zou, J.5
  • 57
    • 0033179161 scopus 로고    scopus 로고
    • Inhibition of in vitro angiogenesis by platelet factor-4-derived peptides and mechanism of action
    • Jouan V., Canron X., Alemany M., Caen J.P., Quentin G., Plouet J., Bikfalvi A. Inhibition of in vitro angiogenesis by platelet factor-4-derived peptides and mechanism of action. Blood 1999, 94:984-993.
    • (1999) Blood , vol.94 , pp. 984-993
    • Jouan, V.1    Canron, X.2    Alemany, M.3    Caen, J.P.4    Quentin, G.5    Plouet, J.6    Bikfalvi, A.7
  • 58
    • 0035929606 scopus 로고    scopus 로고
    • Solution structure and interaction with basic and acidic fibroblast growth factor of a 3-kDa human platelet factor-4 fragment with antiangiogenic activity
    • Lozano R.M., Redondo-Horcajo M., Jimenez M.A., Zilberberg L., Cuevas P., Bikfalvi A., Rico M., Gimenez-Gallego G. Solution structure and interaction with basic and acidic fibroblast growth factor of a 3-kDa human platelet factor-4 fragment with antiangiogenic activity. J. Biol. Chem. 2001, 276:35723-35734.
    • (2001) J. Biol. Chem. , vol.276 , pp. 35723-35734
    • Lozano, R.M.1    Redondo-Horcajo, M.2    Jimenez, M.A.3    Zilberberg, L.4    Cuevas, P.5    Bikfalvi, A.6    Rico, M.7    Gimenez-Gallego, G.8
  • 62
    • 0028800935 scopus 로고
    • High activity suppression of myeloid progenitor proliferation by chimeric mutants of interleukin 8 and platelet factor 4
    • Daly T.J., LaRosa G.J., Dolich S., Maione T.E., Cooper S., Broxmeyer H.E. High activity suppression of myeloid progenitor proliferation by chimeric mutants of interleukin 8 and platelet factor 4. J. Biol. Chem. 1995, 270:23282-23292.
    • (1995) J. Biol. Chem. , vol.270 , pp. 23282-23292
    • Daly, T.J.1    LaRosa, G.J.2    Dolich, S.3    Maione, T.E.4    Cooper, S.5    Broxmeyer, H.E.6
  • 66
    • 0024478056 scopus 로고
    • Identification and characterization of PF4varl, a human gene variant of platelet factor 4
    • Green C.J., Charles R.S., Edwards B.F., Johnson P.H. Identification and characterization of PF4varl, a human gene variant of platelet factor 4. Mol. Cell Biol. 1989, 9:1445-1451.
    • (1989) Mol. Cell Biol. , vol.9 , pp. 1445-1451
    • Green, C.J.1    Charles, R.S.2    Edwards, B.F.3    Johnson, P.H.4
  • 67
    • 34250838704 scopus 로고    scopus 로고
    • Platelet factor-4 variant chemokine CXCL4L1 inhibits melanoma and lung carcinoma growth and metastasis by preventing angiogenesis
    • Struyf S., Burdick M.D., Peeters E., Van den Broeck K., Dillen C., Proost P., Van Damme J., Strieter R.M. Platelet factor-4 variant chemokine CXCL4L1 inhibits melanoma and lung carcinoma growth and metastasis by preventing angiogenesis. Cancer Res. 2007, 67:5940-5948.
    • (2007) Cancer Res. , vol.67 , pp. 5940-5948
    • Struyf, S.1    Burdick, M.D.2    Peeters, E.3    Van den Broeck, K.4    Dillen, C.5    Proost, P.6    Van Damme, J.7    Strieter, R.M.8


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