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Volumn 13, Issue , 2013, Pages

A novel panel of biomarkers in distinction of small well-differentiated HCC from dysplastic nodules and outcome values

Author keywords

Aminoacylase 1; Glypican 3; High grade dysplastic nodules; Sequestosome 1; Well differentiated hepatocellular carcinoma

Indexed keywords

ALPHA FETOPROTEIN; AMINOACYLASE; GLYPICAN 3; SEQUESTOSOME 1; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 84875355529     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-161     Document Type: Article
Times cited : (23)

References (40)
  • 1
    • 14944385553 scopus 로고    scopus 로고
    • Global cancer statistics, 2002
    • 10.3322/canjclin.55.2.74, 15761078
    • Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005, 55(2):74-108. 10.3322/canjclin.55.2.74, 15761078.
    • (2005) CA Cancer J Clin , vol.55 , Issue.2 , pp. 74-108
    • Parkin, D.M.1    Bray, F.2    Ferlay, J.3    Pisani, P.4
  • 2
    • 14544292426 scopus 로고    scopus 로고
    • Preneoplastic lesions in human hepatocarcinogenesis
    • 10.1111/j.1478-3231.2005.01016.x, 15698394
    • Libbrecht L, Desmet V, Roskams T. Preneoplastic lesions in human hepatocarcinogenesis. Liver Int 2005, 25(1):16-27. 10.1111/j.1478-3231.2005.01016.x, 15698394.
    • (2005) Liver Int , vol.25 , Issue.1 , pp. 16-27
    • Libbrecht, L.1    Desmet, V.2    Roskams, T.3
  • 4
    • 0030057130 scopus 로고    scopus 로고
    • Clonal analysis of precancerous lesion of hepatocellular carcinoma
    • 10.1053/gast.1996.v111.pm8690212, 8690212
    • Aihara T, Noguchi S, Sasaki Y, Nakano H, Monden M, Imaoka S. Clonal analysis of precancerous lesion of hepatocellular carcinoma. Gastroenterology 1996, 111(2):455-461. 10.1053/gast.1996.v111.pm8690212, 8690212.
    • (1996) Gastroenterology , vol.111 , Issue.2 , pp. 455-461
    • Aihara, T.1    Noguchi, S.2    Sasaki, Y.3    Nakano, H.4    Monden, M.5    Imaoka, S.6
  • 5
    • 0036699940 scopus 로고    scopus 로고
    • Molecular pathogenesis of human hepatocellular carcinoma
    • 10.1038/ng0802-339, 12149612
    • Thorgeirsson SS, Grisham JW. Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet 2002, 31(4):339-346. 10.1038/ng0802-339, 12149612.
    • (2002) Nat Genet , vol.31 , Issue.4 , pp. 339-346
    • Thorgeirsson, S.S.1    Grisham, J.W.2
  • 6
    • 0036171140 scopus 로고    scopus 로고
    • Detection of nodules in liver cirrhosis: spiral computed tomography or magnetic resonance imaging? A prospective study of 88 nodules in 34 patients
    • 10.1097/00042737-200202000-00010, 11981340
    • de Ledinghen V, Laharie D, Lecesne R, Le Bail B, Winnock M, Bernard PH, Saric J, Couzigou P, Balabaud C, Bioulac-Sage P. Detection of nodules in liver cirrhosis: spiral computed tomography or magnetic resonance imaging? A prospective study of 88 nodules in 34 patients. Eur J Gastroenterol Hepatol 2002, 14(2):159-165. 10.1097/00042737-200202000-00010, 11981340.
    • (2002) Eur J Gastroenterol Hepatol , vol.14 , Issue.2 , pp. 159-165
    • de Ledinghen, V.1    Laharie, D.2    Lecesne, R.3    Le Bail, B.4    Winnock, M.5    Bernard, P.H.6    Saric, J.7    Couzigou, P.8    Balabaud, C.9    Bioulac-Sage, P.10
  • 7
    • 4644358555 scopus 로고    scopus 로고
    • Imaging of dysplastic nodules and small hepatocellular carcinomas: experience with explanted livers
    • Krinsky G. Imaging of dysplastic nodules and small hepatocellular carcinomas: experience with explanted livers. Intervirology 2004, 47(3-5):191-198.
    • (2004) Intervirology , vol.47 , Issue.3-5 , pp. 191-198
    • Krinsky, G.1
  • 8
    • 0032712149 scopus 로고    scopus 로고
    • The vascular profile of regenerative and dysplastic nodules of the cirrhotic liver: implications for diagnosis and classification
    • 10.1002/hep.510300507, 10534338
    • Roncalli M, Roz E, Coggi G, Di Rocco MG, Bossi P, Minola E, Gambacorta M, Borzio M. The vascular profile of regenerative and dysplastic nodules of the cirrhotic liver: implications for diagnosis and classification. Hepatology 1999, 30(5):1174-1178. 10.1002/hep.510300507, 10534338.
    • (1999) Hepatology , vol.30 , Issue.5 , pp. 1174-1178
    • Roncalli, M.1    Roz, E.2    Coggi, G.3    Di Rocco, M.G.4    Bossi, P.5    Minola, E.6    Gambacorta, M.7    Borzio, M.8
  • 9
    • 0037223571 scopus 로고    scopus 로고
    • Expression profiling in multistage hepatocarcinogenesis: identification of HSP70 as a molecular marker of early hepatocellular carcinoma
    • 10.1053/jhep.2003.50022, 12500205
    • Chuma M, Sakamoto M, Yamazaki K, Ohta T, Ohki M, Asaka M, Hirohashi S. Expression profiling in multistage hepatocarcinogenesis: identification of HSP70 as a molecular marker of early hepatocellular carcinoma. Hepatology 2003, 37(1):198-207. 10.1053/jhep.2003.50022, 12500205.
    • (2003) Hepatology , vol.37 , Issue.1 , pp. 198-207
    • Chuma, M.1    Sakamoto, M.2    Yamazaki, K.3    Ohta, T.4    Ohki, M.5    Asaka, M.6    Hirohashi, S.7
  • 11
    • 40849113385 scopus 로고    scopus 로고
    • Distinction of hepatocellular carcinoma from benign hepatic mimickers using Glypican-3 and CD34 immunohistochemistry
    • 10.1097/PAS.0b013e318158142f, 18300806
    • Coston WM, Loera S, Lau SK, Ishizawa S, Jiang Z, Wu CL, Yen Y, Weiss LM, Chu PG. Distinction of hepatocellular carcinoma from benign hepatic mimickers using Glypican-3 and CD34 immunohistochemistry. Am J Surg Pathol 2008, 32(3):433-444. 10.1097/PAS.0b013e318158142f, 18300806.
    • (2008) Am J Surg Pathol , vol.32 , Issue.3 , pp. 433-444
    • Coston, W.M.1    Loera, S.2    Lau, S.K.3    Ishizawa, S.4    Jiang, Z.5    Wu, C.L.6    Yen, Y.7    Weiss, L.M.8    Chu, P.G.9
  • 12
    • 0038786861 scopus 로고    scopus 로고
    • Glypican-3: a novel serum and histochemical marker for hepatocellular carcinoma
    • 10.1016/S0016-5085(03)00689-9, 12851874
    • Capurro M, Wanless IR, Sherman M, Deboer G, Shi W, Miyoshi E, Filmus J. Glypican-3: a novel serum and histochemical marker for hepatocellular carcinoma. Gastroenterology 2003, 125(1):89-97. 10.1016/S0016-5085(03)00689-9, 12851874.
    • (2003) Gastroenterology , vol.125 , Issue.1 , pp. 89-97
    • Capurro, M.1    Wanless, I.R.2    Sherman, M.3    Deboer, G.4    Shi, W.5    Miyoshi, E.6    Filmus, J.7
  • 13
    • 61749103943 scopus 로고    scopus 로고
    • The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma
    • 10.1016/j.jhep.2008.11.014, 19231003
    • Di Tommaso L, Destro A, Seok JY, Balladore E, Terracciano L, Sangiovanni A, Iavarone M, Colombo M, Jang JJ, Yu E. The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma. J Hepatol 2009, 50(4):746-754. 10.1016/j.jhep.2008.11.014, 19231003.
    • (2009) J Hepatol , vol.50 , Issue.4 , pp. 746-754
    • Di Tommaso, L.1    Destro, A.2    Seok, J.Y.3    Balladore, E.4    Terracciano, L.5    Sangiovanni, A.6    Iavarone, M.7    Colombo, M.8    Jang, J.J.9    Yu, E.10
  • 14
    • 67549119075 scopus 로고    scopus 로고
    • Agrin and CD34 immunohistochemistry for the discrimination of benign versus malignant hepatocellular lesions
    • 10.1097/PAS.0b013e318194b3ea, 19194276
    • Tatrai P, Somoracz A, Batmunkh E, Schirmacher P, Kiss A, Schaff Z, Nagy P, Kovalszky I. Agrin and CD34 immunohistochemistry for the discrimination of benign versus malignant hepatocellular lesions. Am J Surg Pathol 2009, 33(6):874-885. 10.1097/PAS.0b013e318194b3ea, 19194276.
    • (2009) Am J Surg Pathol , vol.33 , Issue.6 , pp. 874-885
    • Tatrai, P.1    Somoracz, A.2    Batmunkh, E.3    Schirmacher, P.4    Kiss, A.5    Schaff, Z.6    Nagy, P.7    Kovalszky, I.8
  • 15
    • 79961237681 scopus 로고    scopus 로고
    • ITRAQ-2DLC-ESI-MS/MS based identification of a new set of immunohistochemical biomarkers for classification of dysplastic nodules and small hepatocellular carcinoma
    • 10.1021/pr200482t, 21631109
    • Jin GZ, Li Y, Cong WM, Yu H, Dong H, Shu H, Liu XH, Yan GQ, Zhang L, Zhang Y. iTRAQ-2DLC-ESI-MS/MS based identification of a new set of immunohistochemical biomarkers for classification of dysplastic nodules and small hepatocellular carcinoma. J Proteome Res 2011, 10(8):3418-3428. 10.1021/pr200482t, 21631109.
    • (2011) J Proteome Res , vol.10 , Issue.8 , pp. 3418-3428
    • Jin, G.Z.1    Li, Y.2    Cong, W.M.3    Yu, H.4    Dong, H.5    Shu, H.6    Liu, X.H.7    Yan, G.Q.8    Zhang, L.9    Zhang, Y.10
  • 16
    • 84855190247 scopus 로고    scopus 로고
    • Glypican-3, a novel prognostic marker of hepatocellular cancer, is related with postoperative metastasis and recurrence in hepatocellular cancer patients
    • 10.1007/s11033-011-0745-y, 21655958
    • Ning S, Bin C, Na H, Peng S, Yi D, Xiang-hua Y, Fang-yin Z, Da-yong Z, Rong-cheng L. Glypican-3, a novel prognostic marker of hepatocellular cancer, is related with postoperative metastasis and recurrence in hepatocellular cancer patients. Mol Biol Rep 2012, 39(1):351-357. 10.1007/s11033-011-0745-y, 21655958.
    • (2012) Mol Biol Rep , vol.39 , Issue.1 , pp. 351-357
    • Ning, S.1    Bin, C.2    Na, H.3    Peng, S.4    Yi, D.5    Xiang-hua, Y.6    Fang-yin, Z.7    Da-yong, Z.8    Rong-cheng, L.9
  • 19
    • 84865032380 scopus 로고    scopus 로고
    • Recurrence and poor prognosis following resection of small hepatitis B-related hepatocellular carcinoma lesions are associated with aberrant tumor expression profiles of glypican 3 and osteopontin
    • Epub ahead of print
    • Yu MC, Lee YS, Lin SE, Wu HY, Chen TC, Lee WC, Chen MF, Tsai CN. Recurrence and poor prognosis following resection of small hepatitis B-related hepatocellular carcinoma lesions are associated with aberrant tumor expression profiles of glypican 3 and osteopontin. Ann Surg Oncol 2011, Epub ahead of print.
    • (2011) Ann Surg Oncol
    • Yu, M.C.1    Lee, Y.S.2    Lin, S.E.3    Wu, H.Y.4    Chen, T.C.5    Lee, W.C.6    Chen, M.F.7    Tsai, C.N.8
  • 20
    • 61949171989 scopus 로고    scopus 로고
    • Pathologic diagnosis of early hepatocellular carcinoma: a report of the international consensus group for hepatocellular neoplasia
    • Pathologic diagnosis of early hepatocellular carcinoma: a report of the international consensus group for hepatocellular neoplasia. Hepatology 2009, 49(2):658-664.
    • (2009) Hepatology , vol.49 , Issue.2 , pp. 658-664
  • 23
    • 33750964740 scopus 로고    scopus 로고
    • Number of CD4+ cells and location of forkhead box protein P3-positive cells in diagnostic follicular lymphoma tissue microarrays correlates with outcome
    • 10.1200/JCO.2006.06.4642, 17033038
    • Lee AM, Clear AJ, Calaminici M, Davies AJ, Jordan S, MacDougall F, Matthews J, Norton AJ, Gribben JG, Lister TA. Number of CD4+ cells and location of forkhead box protein P3-positive cells in diagnostic follicular lymphoma tissue microarrays correlates with outcome. J Clin Oncol 2006, 24(31):5052-5059. 10.1200/JCO.2006.06.4642, 17033038.
    • (2006) J Clin Oncol , vol.24 , Issue.31 , pp. 5052-5059
    • Lee, A.M.1    Clear, A.J.2    Calaminici, M.3    Davies, A.J.4    Jordan, S.5    MacDougall, F.6    Matthews, J.7    Norton, A.J.8    Gribben, J.G.9    Lister, T.A.10
  • 24
    • 45749137283 scopus 로고    scopus 로고
    • High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma
    • 10.1200/JCO.2007.15.6521, 18509183
    • Zhu XD, Zhang JB, Zhuang PY, Zhu HG, Zhang W, Xiong YQ, Wu WZ, Wang L, Tang ZY, Sun HC. High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma. J Clin Oncol 2008, 26(16):2707-2716. 10.1200/JCO.2007.15.6521, 18509183.
    • (2008) J Clin Oncol , vol.26 , Issue.16 , pp. 2707-2716
    • Zhu, X.D.1    Zhang, J.B.2    Zhuang, P.Y.3    Zhu, H.G.4    Zhang, W.5    Xiong, Y.Q.6    Wu, W.Z.7    Wang, L.8    Tang, Z.Y.9    Sun, H.C.10
  • 25
    • 54049129625 scopus 로고    scopus 로고
    • Pivotal evaluation of the accuracy of a biomarker used for classification or prediction: standards for study design
    • 10.1093/jnci/djn326, 2567415, 18840817
    • Pepe MS, Feng Z, Janes H, Bossuyt PM, Potter JD. Pivotal evaluation of the accuracy of a biomarker used for classification or prediction: standards for study design. J Natl Cancer Inst 2008, 100(20):1432-1438. 10.1093/jnci/djn326, 2567415, 18840817.
    • (2008) J Natl Cancer Inst , vol.100 , Issue.20 , pp. 1432-1438
    • Pepe, M.S.1    Feng, Z.2    Janes, H.3    Bossuyt, P.M.4    Potter, J.D.5
  • 26
    • 21344450714 scopus 로고    scopus 로고
    • Characterization of small nodules in cirrhosis by assessment of vascularity: the problem of hypovascular hepatocellular carcinoma
    • 10.1002/hep.20728, 15954118
    • Bolondi L, Gaiani S, Celli N, Golfieri R, Grigioni WF, Leoni S, Venturi AM, Piscaglia F. Characterization of small nodules in cirrhosis by assessment of vascularity: the problem of hypovascular hepatocellular carcinoma. Hepatology 2005, 42(1):27-34. 10.1002/hep.20728, 15954118.
    • (2005) Hepatology , vol.42 , Issue.1 , pp. 27-34
    • Bolondi, L.1    Gaiani, S.2    Celli, N.3    Golfieri, R.4    Grigioni, W.F.5    Leoni, S.6    Venturi, A.M.7    Piscaglia, F.8
  • 27
    • 1242329819 scopus 로고    scopus 로고
    • Focus on dysplastic nodules and early hepatocellular carcinoma: an Eastern point of view
    • Kojiro M. Focus on dysplastic nodules and early hepatocellular carcinoma: an Eastern point of view. Liver Transpl 2004, 10(2 Suppl 1):S3-S8.
    • (2004) Liver Transpl , vol.10 , Issue.2 SUPPL. 1
    • Kojiro, M.1
  • 28
    • 79958219307 scopus 로고    scopus 로고
    • EZH2 protein: a promising immunomarker for the detection of hepatocellular carcinomas in liver needle biopsies
    • 10.1136/gut.2010.231993, 21330577
    • Cai MY, Tong ZT, Zheng F, Liao YJ, Wang Y, Rao HL, Chen YC, Wu QL, Liu YH, Guan XY. EZH2 protein: a promising immunomarker for the detection of hepatocellular carcinomas in liver needle biopsies. Gut 2011, 60(7):967-976. 10.1136/gut.2010.231993, 21330577.
    • (2011) Gut , vol.60 , Issue.7 , pp. 967-976
    • Cai, M.Y.1    Tong, Z.T.2    Zheng, F.3    Liao, Y.J.4    Wang, Y.5    Rao, H.L.6    Chen, Y.C.7    Wu, Q.L.8    Liu, Y.H.9    Guan, X.Y.10
  • 29
    • 33750430854 scopus 로고    scopus 로고
    • Glypican-3 expression distinguishes small hepatocellular carcinomas from cirrhosis, dysplastic nodules, and focal nodular hyperplasia-like nodules
    • 10.1097/01.pas.0000213323.97294.9a, 17063081
    • Libbrecht L, Severi T, Cassiman D, Vander Borght S, Pirenne J, Nevens F, Verslype C, van Pelt J, Roskams T. Glypican-3 expression distinguishes small hepatocellular carcinomas from cirrhosis, dysplastic nodules, and focal nodular hyperplasia-like nodules. Am J Surg Pathol 2006, 30(11):1405-1411. 10.1097/01.pas.0000213323.97294.9a, 17063081.
    • (2006) Am J Surg Pathol , vol.30 , Issue.11 , pp. 1405-1411
    • Libbrecht, L.1    Severi, T.2    Cassiman, D.3    Vander Borght, S.4    Pirenne, J.5    Nevens, F.6    Verslype, C.7    van Pelt, J.8    Roskams, T.9
  • 31
    • 0019879423 scopus 로고
    • Purification, characterization and possible function of alpha-N-acylamino acid hydrolase from bovine liver
    • 10.1016/0005-2744(81)90227-8, 7306559
    • Gade W, Brown JL. Purification, characterization and possible function of alpha-N-acylamino acid hydrolase from bovine liver. Biochim Biophys Acta 1981, 662(1):86-93. 10.1016/0005-2744(81)90227-8, 7306559.
    • (1981) Biochim Biophys Acta , vol.662 , Issue.1 , pp. 86-93
    • Gade, W.1    Brown, J.L.2
  • 32
    • 0030067819 scopus 로고    scopus 로고
    • A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes
    • 189923, 8551575
    • Devergne O, Hummel M, Koeppen H, Le Beau MM, Nathanson EC, Kieff E, Birkenbach M. A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes. J Virol 1996, 70(2):1143-1153. 189923, 8551575.
    • (1996) J Virol , vol.70 , Issue.2 , pp. 1143-1153
    • Devergne, O.1    Hummel, M.2    Koeppen, H.3    Le Beau, M.M.4    Nathanson, E.C.5    Kieff, E.6    Birkenbach, M.7
  • 33
    • 0035896518 scopus 로고    scopus 로고
    • The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor
    • 10.1074/jbc.C000869200, 11244088
    • Wooten MW, Seibenhener ML, Mamidipudi V, Diaz-Meco MT, Barker PA, Moscat J. The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor. J Biol Chem 2001, 276(11):7709-7712. 10.1074/jbc.C000869200, 11244088.
    • (2001) J Biol Chem , vol.276 , Issue.11 , pp. 7709-7712
    • Wooten, M.W.1    Seibenhener, M.L.2    Mamidipudi, V.3    Diaz-Meco, M.T.4    Barker, P.A.5    Moscat, J.6
  • 34
    • 0033153320 scopus 로고    scopus 로고
    • The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation
    • 10.1093/emboj/18.11.3044, 1171386, 10356400
    • Sanz L, Sanchez P, Lallena MJ, Diaz-Meco MT, Moscat J. The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation. EMBO J 1999, 18(11):3044-3053. 10.1093/emboj/18.11.3044, 1171386, 10356400.
    • (1999) EMBO J , vol.18 , Issue.11 , pp. 3044-3053
    • Sanz, L.1    Sanchez, P.2    Lallena, M.J.3    Diaz-Meco, M.T.4    Moscat, J.5
  • 36
    • 34447569148 scopus 로고    scopus 로고
    • The Simpson-Golabi-Behmel syndrome causative glypican-3, binds to and inhibits the dipeptidyl peptidase activity of CD26
    • 10.1002/pmic.200600654, 17549790
    • Davoodi J, Kelly J, Gendron NH, MacKenzie AE. The Simpson-Golabi-Behmel syndrome causative glypican-3, binds to and inhibits the dipeptidyl peptidase activity of CD26. Proteomics 2007, 7(13):2300-2310. 10.1002/pmic.200600654, 17549790.
    • (2007) Proteomics , vol.7 , Issue.13 , pp. 2300-2310
    • Davoodi, J.1    Kelly, J.2    Gendron, N.H.3    MacKenzie, A.E.4
  • 37
    • 0032851528 scopus 로고    scopus 로고
    • A clinical and molecular study of a patient with Simpson-Golabi-Behmel syndrome
    • 10.1007/s100380050170, 10496077
    • Okamoto N, Yagi M, Imura K, Wada Y. A clinical and molecular study of a patient with Simpson-Golabi-Behmel syndrome. J Hum Genet 1999, 44(5):327-329. 10.1007/s100380050170, 10496077.
    • (1999) J Hum Genet , vol.44 , Issue.5 , pp. 327-329
    • Okamoto, N.1    Yagi, M.2    Imura, K.3    Wada, Y.4
  • 38
    • 84866296481 scopus 로고    scopus 로고
    • Expression of GPC3 protein and its significance in lung squamous cell carcinoma
    • 10.1007/s12032-011-9973-1, 21556932
    • Lin Q, Xiong LW, Pan XF, Gen JF, Bao GL, Sha HF, Feng JX, Ji CY, Chen M. Expression of GPC3 protein and its significance in lung squamous cell carcinoma. Med Oncol 2012, 29(2):663-669. 10.1007/s12032-011-9973-1, 21556932.
    • (2012) Med Oncol , vol.29 , Issue.2 , pp. 663-669
    • Lin, Q.1    Xiong, L.W.2    Pan, X.F.3    Gen, J.F.4    Bao, G.L.5    Sha, H.F.6    Feng, J.X.7    Ji, C.Y.8    Chen, M.9
  • 39
    • 0033651369 scopus 로고    scopus 로고
    • Clinical characteristics and prognosis of hepatocellular carcinoma: analysis based on serum alpha-fetoprotein levels
    • 10.1097/00004836-200012000-00007, 11129271
    • Tangkijvanich P, Anukulkarnkusol N, Suwangool P, Lertmaharit S, Hanvivatvong O, Kullavanijaya P, Poovorawan Y. Clinical characteristics and prognosis of hepatocellular carcinoma: analysis based on serum alpha-fetoprotein levels. J Clin Gastroenterol 2000, 31(4):302-308. 10.1097/00004836-200012000-00007, 11129271.
    • (2000) J Clin Gastroenterol , vol.31 , Issue.4 , pp. 302-308
    • Tangkijvanich, P.1    Anukulkarnkusol, N.2    Suwangool, P.3    Lertmaharit, S.4    Hanvivatvong, O.5    Kullavanijaya, P.6    Poovorawan, Y.7
  • 40
    • 77957359351 scopus 로고    scopus 로고
    • PEBP1 downregulation is associated to poor prognosis in HCC related to hepatitis B infection
    • 10.1016/j.jhep.2010.05.019, 20739083
    • Xu YF, Yi Y, Qiu SJ, Gao Q, Li YW, Dai CX, Cai MY, Ju MJ, Zhou J, Zhang BH. PEBP1 downregulation is associated to poor prognosis in HCC related to hepatitis B infection. J Hepatol 2010, 53(5):872-879. 10.1016/j.jhep.2010.05.019, 20739083.
    • (2010) J Hepatol , vol.53 , Issue.5 , pp. 872-879
    • Xu, Y.F.1    Yi, Y.2    Qiu, S.J.3    Gao, Q.4    Li, Y.W.5    Dai, C.X.6    Cai, M.Y.7    Ju, M.J.8    Zhou, J.9    Zhang, B.H.10


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