Pyrosequencing analysis of APC methylation level in human prostate tissues: A molecular marker for prostate cancer

Korean Journal of Urology

Volumn 54, Issue 3, 2013, Pages 194-198

  Yoon, Hyung Yoon ^a   Kim, Young Won ^a   Kang, Ho Won ^a   Kim, Won Tae ^a   Yun, Seok Joong ^a   Lee, Sang Cheol ^a   Kim, Wun Jae ^a   Kim, Yong June ^a  

^a Chungbuk National University College of Medicine   (South Korea)

Author keywords

Adenomatous polyposis coli; Biological markers; DNA methylation; Prostatic neoplasms; Sequence analysis

Indexed keywords

APC PROTEIN; PROSTATE SPECIFIC ANTIGEN;

AGED; ARTICLE; DNA EXTRACTION; GLEASON SCORE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; METHYLATION; POLYMERASE CHAIN REACTION; PREDICTIVE VALUE; PROSTATE CANCER; PROSTATE HYPERTROPHY; PROSTATE VOLUME; PYROSEQUENCING; SENSITIVITY AND SPECIFICITY;

EID: 84875348441     PISSN: 20056737     EISSN: 20056745     Source Type: Journal    
DOI: 10.4111/kju.2013.54.3.194     Document Type: Article

References (17)

1. van Vlodrop IJ, Niessen HE, Derks S, Baldewijns MM, van Criekinge W, Herman JG, et al. Analysis of promoter CpG island hypermethylation in cancer: location, location, location! Clin Cancer Res 2011;17:4225-31.
2. Kim WJ, Kim YJ. Epigenetic biomarkers in urothelial bladder cancer. Expert Rev Mol Diagn 2009;9:259-69.
3. Hoque MO. DNA methylation changes in prostate cancer: current developments and future clinical implementation. Expert Rev Mol Diagn 2009;9:243-57.
4. Ushijima T. Detection and interpretation of altered methylation patterns in cancer cells. Nat Rev Cancer 2005;5:223-31.
5. Kim EJ, Kim YJ, Jeong P, Ha YS, Bae SC, Kim WJ. Methylation of the RUNX3 promoter as a potential prognostic marker for bladder tumor. J Urol 2008;180:1141-5.
6. Kim YJ, Yoon HY, Kim SK, Kim YW, Kim EJ, Kim IY, et al. EFEMP1 as a novel DNA methylation marker for prostate cancer: array-based DNA methylation and expression profiling. Clin Cancer Res 2011;17:4523-30.
7. Marsh S. Pyrosequencing applications. Methods Mol Biol 2007; 373:15-24.
8. Vasiljevic N, Wu K, Brentnall AR, Kim DC, Thorat MA, Kudahetti SC, et al. Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing. Dis Markers 2011;30:151-61.
9. Kim JH, Dhanasekaran SM, Prensner JR, Cao X, Robinson D, Kalyana-Sundaram S, et al. Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer. Genome Res 2011;21:1028-41.
10. Rai K, Sarkar S, Broadbent TJ, Voas M, Grossmann KF, Nadauld LD, et al. DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC. Cell 2010;142: 930-42.
11. Richiardi L, Fiano V, Vizzini L, De Marco L, Delsedime L, Akre O, et al. Promoter methylation in APC, RUNX3, and GSTP1 and mortality in prostate cancer patients. J Clin Oncol 2009;27: 3161-8.
12. Henrique R, Ribeiro FR, Fonseca D, Hoque MO, Carvalho AL, Costa VL, et al. High promoter methylation levels of APC predict poor prognosis in sextant biopsies from prostate cancer patients. Clin Cancer Res 2007;13:6122-9.
13. Jeronimo C, Henrique R, Hoque MO, Mambo E, Ribeiro FR, Varzim G, et al. A quantitative promoter methylation profile of prostate cancer. Clin Cancer Res 2004;10:8472-8.
14. Bastian PJ, Ellinger J, Wellmann A, Wernert N, Heukamp LC, Muller SC, et al. Diagnostic and prognostic information in prostate cancer with the help of a small set of hypermethylated gene loci. Clin Cancer Res 2005;11:4097-106.
15. Yegnasubramanian S, Kowalski J, Gonzalgo ML, Zahurak M, Piantadosi S, Walsh PC, et al. Hypermethylation of CpG islands in primary and metastatic human prostate cancer. Cancer Res 2004;64:1975-86.
16. Baden J, Green G, Painter J, Curtin K, Markiewicz J, Jones J, et al. Multicenter evaluation of an investigational prostate cancer methylation assay. J Urol 2009;182:1186-93.
17. Gavert N, Ben-Ze'ev A. beta-Catenin signaling in biological control and cancer. J Cell Biochem 2007;102:820-8.