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Volumn 37, Issue 4, 2012, Pages 335-356

Optimizing therapy for radioactive iodine-refractory differentiated thyroid cancer: Current state of the art and future directions

Author keywords

Carcinoma, papillary; Drug therapy; Protein tyrosine kinases; Thyroid neoplasms

Indexed keywords

ANTITHYROID AGENT; AXITINIB; BISPHOSPHONIC ACID DERIVATIVE; CABOZANTINIB; DABRAFENIB; DENOSUMAB; EVEROLIMUS; EXEMESTANE; FLUORODEOXYGLUCOSE F 18; GEFITINIB; LENVATINIB; LIVER ENZYME; MOTESANIB; PAZOPANIB; PLACEBO; PROTEIN TYROSINE KINASE INHIBITOR; RADIOACTIVE IODINE; SELUMETINIB; SORAFENIB; SUNITINIB; TEMSIROLIMUS; THYROGLOBULIN; THYROGLOBULIN ANTIBODY; THYROTROPIN; TIPIFARNIB; TRIACYLGLYCEROL LIPASE; UNINDEXED DRUG; VANDETANIB; VEMURAFENIB; ZOLEDRONIC ACID;

EID: 84875305916     PISSN: 03911977     EISSN: 18271634     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (40)

References (99)
  • 3
    • 79957467074 scopus 로고    scopus 로고
    • Metastatic dormancy and progression in thyroid cancer: Targeting cells in the metastatic frontier
    • Ringel MD. Metastatic dormancy and progression in thyroid cancer: targeting cells in the metastatic frontier. Thyroid 2011;21(5):487-92.
    • (2011) Thyroid , vol.21 , Issue.5 , pp. 487-492
    • Ringel, M.D.1
  • 4
    • 79251484686 scopus 로고    scopus 로고
    • Do histological, immunohistochemical, and metabolic (radioiodine and fluorodeoxyglucose uptakes) patterns of metastatic thyroid cancer correlate with patient outcome?
    • Deandreis D, Al Ghuzlan A, Leboulleux S, Lacroix L, Garsi JP, Talbot M et al. Do histological, immunohistochemical, and metabolic (radioiodine and fluorodeoxyglucose uptakes) patterns of metastatic thyroid cancer correlate with patient outcome? Endocr Relat Cancer 2011;18(1):159-69.
    • (2011) Endocr Relat Cancer , vol.18 , Issue.1 , pp. 159-169
    • Deandreis, D.1    Al Ghuzlan, A.2    Leboulleux, S.3    Lacroix, L.4    Garsi, J.P.5    Talbot, M.6
  • 6
    • 84864711852 scopus 로고    scopus 로고
    • Post-Radioiodine Treatment Whole Body Scan in the Era of Fluorodesoxyglucose Positron Emission Tomography for Differentiated Thyroid Carcinoma with elevated serum thyroglobulin levels
    • Leboulleux S, El Bez I, Borget I, Elleuch M, Deandreis D, Al Ghuzlan A et al. Post-Radioiodine Treatment Whole Body Scan in the Era of Fluorodesoxyglucose Positron Emission Tomography for Differentiated Thyroid Carcinoma with elevated serum thyroglobulin levels. Thyroid 2012.
    • (2012) Thyroid
    • Leboulleux, S.1    El Bez, I.2    Borget, I.3    Elleuch, M.4    Deandreis, D.5    Al Ghuzlan, A.6
  • 7
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000;92:205-16.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3    Wanders, J.4    Kaplan, R.S.5    Rubinstein, L.6
  • 10
    • 66149139452 scopus 로고    scopus 로고
    • From RECIST to PERCIST: Evolving Considerations for PET response criteria in solid tumors
    • Wahl RL, Jacene H, Kasamon Y, Lodge MA. From RECIST to PERCIST: Evolving Considerations for PET response criteria in solid tumors. J Nucl Med 2009;50(Suppl 1):122S-50S.
    • (2009) J Nucl Med , vol.50 , Issue.SUPPL. 1
    • Wahl, R.L.1    Jacene, H.2    Kasamon, Y.3    Lodge, M.A.4
  • 13
    • 67649556616 scopus 로고    scopus 로고
    • Postoperative external beam radiotherapy for differentiated thyroid cancer: Outcomes and morbidity with conformal treatment
    • Schwartz DL, Lobo MJ, Ang KK, Morrison WH, Rosenthal DI, Ahamad A et al. Postoperative external beam radiotherapy for differentiated thyroid cancer: outcomes and morbidity with conformal treatment. Int J Radiat Oncol Biol Phys 2009;74:1083-91.
    • (2009) Int J Radiat Oncol Biol Phys , vol.74 , pp. 1083-1091
    • Schwartz, D.L.1    Lobo, M.J.2    Ang, K.K.3    Morrison, W.H.4    Rosenthal, D.I.5    Ahamad, A.6
  • 14
    • 79954480769 scopus 로고    scopus 로고
    • A risk-adapted approach to the use of radioactive iodine and external beam radiation in the treatment of well-differentiated thyroid cancer
    • Tuttle RM, Rondeau G, Lee NY. A risk-adapted approach to the use of radioactive iodine and external beam radiation in the treatment of well-differentiated thyroid cancer. Cancer Control 2011;18:89-95.
    • (2011) Cancer Control , vol.18 , pp. 89-95
    • Tuttle, R.M.1    Rondeau, G.2    Lee, N.Y.3
  • 15
    • 33846806098 scopus 로고    scopus 로고
    • The role of external beam radiotherapy in the treatment of papillary thyroid cancer
    • DOI 10.1677/ERC-06-0039
    • Lee N, Tuttle M. The role of external beam radiotherapy in the treatment of papillary thyroid cancer. Endocr Relat Cancer 2006;13:971-7. (Pubitemid 46212559)
    • (2006) Endocrine-Related Cancer , vol.13 , Issue.4 , pp. 971-977
    • Lee, N.1    Tuttle, M.2
  • 17
    • 37449012330 scopus 로고    scopus 로고
    • The role of radiation therapy in the management of thyroid cancer
    • Strasser JF, Raben A, Koprowski C. The role of radiation therapy in the management of thyroid cancer. Surg Oncol Clin N Am 2008;17:219-32, x.
    • (2008) Surg Oncol Clin N Am , vol.17
    • Strasser, J.F.1    Raben, A.2    Koprowski, C.3
  • 18
    • 73949149605 scopus 로고    scopus 로고
    • Tracheoesophageal fistula formation in patients with lung cancer treated with chemoradiation and bevacizumab
    • Spigel DR, Hainsworth JD, Yardley DA, Raefsky E, Patton J, Peacock N et al. Tracheoesophageal fistula formation in patients with lung cancer treated with chemoradiation and bevacizumab. J Clin Oncol 2010;28:43-8.
    • (2010) J Clin Oncol , vol.28 , pp. 43-48
    • Spigel, D.R.1    Hainsworth, J.D.2    Yardley, D.A.3    Raefsky, E.4    Patton, J.5    Peacock, N.6
  • 20
    • 0034085346 scopus 로고    scopus 로고
    • Bone metastases from thyroid carcinoma: Clinical characteristics and prognostic variables in one hundred forty-six patients
    • Pittas AG, Adler M, Fazzari M, Tickoo S, Rosai J, Larson SM et al. Bone metastases from thyroid carcinoma: clinical characteristics and prognostic variables in one hundred forty-six patients. Thyroid 2000;10:261-8.
    • (2000) Thyroid , vol.10 , pp. 261-268
    • Pittas, A.G.1    Adler, M.2    Fazzari, M.3    Tickoo, S.4    Rosai, J.5    Larson, S.M.6
  • 21
    • 76749160633 scopus 로고    scopus 로고
    • Prognostic factors and the therapeutic strategy for patients with bone metastasis from differentiated thyroid carcinoma
    • Orita Y, Sugitani I, Matsuura M, Ushijima M, Tsukahara K, Fujimoto Y et al. Prognostic factors and the therapeutic strategy for patients with bone metastasis from differentiated thyroid carcinoma. Surgery 2010;147:424-31.
    • (2010) Surgery , vol.147 , pp. 424-431
    • Orita, Y.1    Sugitani, I.2    Matsuura, M.3    Ushijima, M.4    Tsukahara, K.5    Fujimoto, Y.6
  • 22
    • 37249026112 scopus 로고    scopus 로고
    • Papillary thyroid carcinoma with distant metastases: Survival predictors and the importance of local control
    • DOI 10.1016/j.surg.2007.06.011, PII S0039606007003704
    • Sugitani I, Fujimoto Y, Yamamoto N. Papillary thyroid carcinoma with distant metastases: survival predictors and the importance of local control. Surgery 2008;143:35-42. (Pubitemid 350266026)
    • (2008) Surgery , vol.143 , Issue.1 , pp. 35-42
    • Sugitani, I.1    Fujimoto, Y.2    Yamamoto, N.3
  • 23
    • 84863599516 scopus 로고    scopus 로고
    • Skeletal-Related Events due to Bone Metastases from Differentiated Thyroid Cancer
    • Farooki A, Leung V, Tala H, Tuttle RM. Skeletal-Related Events due to Bone Metastases from Differentiated Thyroid Cancer. J Clin Endocrinol Metab 2012,97:2433-9.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 2433-2439
    • Farooki, A.1    Leung, V.2    Tala, H.3    Tuttle, R.M.4
  • 24
    • 80053463814 scopus 로고    scopus 로고
    • Efficacy and survival analysis of 131I therapy for bone metastases from differentiated thyroid cancer
    • Qiu ZL, Song HJ, Xu YH, Luo QY. Efficacy and survival analysis of 131I therapy for bone metastases from differentiated thyroid cancer. J Clin Endocrinol Metab 2011;96:3078-86.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 3078-3086
    • Qiu, Z.L.1    Song, H.J.2    Xu, Y.H.3    Luo, Q.Y.4
  • 25
    • 78651318407 scopus 로고    scopus 로고
    • Zoledronic acid in the treatment of bone metastases from differentiated thyroid carcinoma
    • Orita Y, Sugitani I, Toda K, Manabe J, Fujimoto Y. Zoledronic acid in the treatment of bone metastases from differentiated thyroid carcinoma. Thyroid 2011;21:31-5.
    • (2011) Thyroid , vol.21 , pp. 31-35
    • Orita, Y.1    Sugitani, I.2    Toda, K.3    Manabe, J.4    Fujimoto, Y.5
  • 26
    • 63749094012 scopus 로고    scopus 로고
    • Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates
    • Fizazi K, Lipton A, Mariette X, Body JJ, Rahim Y, Gralow JR et al. Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates. J Clin Oncol 2009;27:1564-71.
    • (2009) J Clin Oncol , vol.27 , pp. 1564-1571
    • Fizazi, K.1    Lipton, A.2    Mariette, X.3    Body, J.J.4    Rahim, Y.5    Gralow, J.R.6
  • 28
    • 79952761418 scopus 로고    scopus 로고
    • Randomized, double-blind study of denosumab versus zoledronic acid in the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma
    • Henry DH, Costa L, Goldwasser F, Hirsh V, Hungria V, Prausova J et al. Randomized, double-blind study of denosumab versus zoledronic acid in the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma. J Clin Oncol 2011;29:1125-32.
    • (2011) J Clin Oncol , vol.29 , pp. 1125-1132
    • Henry, D.H.1    Costa, L.2    Goldwasser, F.3    Hirsh, V.4    Hungria, V.5    Prausova, J.6
  • 29
    • 79551568488 scopus 로고    scopus 로고
    • Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: A randomized, doubleblind study
    • Stopeck AT, Lipton A, Body JJ, Steger GG, Tonkin K, de Boer RH et al. Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, doubleblind study. J Clin Oncol 2010;28:5132-9.
    • (2010) J Clin Oncol , vol.28 , pp. 5132-5139
    • Stopeck, A.T.1    Lipton, A.2    Body, J.J.3    Steger, G.G.4    Tonkin, K.5    De Boer, R.H.6
  • 30
    • 0038345383 scopus 로고    scopus 로고
    • Management of brain metastases from thyroid carcinoma: A study of 16 pathologically confirmed cases over 25 years
    • DOI 10.1002/cncr.11488
    • McWilliams RR, Giannini C, Hay ID, Atkinson JL, Stafford SL, Buckner JC. Management of brain metastases from thyroid carcinoma: a study of 16 pathologically confirmed cases over 25 years. Cancer 2003;98:356-62. (Pubitemid 36828462)
    • (2003) Cancer , vol.98 , Issue.2 , pp. 356-362
    • McWilliams, R.R.1    Giannini, C.2    Hay, I.D.3    Atkinson, J.L.4    Stafford, S.L.5    Buckner, J.C.6
  • 32
    • 77953609566 scopus 로고    scopus 로고
    • Stereotactic radiosurgery in the management of brain metastases from primary thyroid cancers
    • Bernad DM, Sperduto PW, Souhami L, Jensen AW, Roberge D. Stereotactic radiosurgery in the management of brain metastases from primary thyroid cancers. J Neurooncol 2010;98:249-52.
    • (2010) J Neurooncol , vol.98 , pp. 249-252
    • Bernad, D.M.1    Sperduto, P.W.2    Souhami, L.3    Jensen, A.W.4    Roberge, D.5
  • 37
    • 28344451050 scopus 로고    scopus 로고
    • Laparoscopic radiofrequency thermal ablation for unusual hepatic tumors: Operative indications and outcomes
    • DOI 10.1007/s00464-005-0236-0
    • Berber E, Ari E, Herceg N, Siperstein A. Laparoscopic radiofrequency thermal ablation for unusual hepatic tumors: operative indications and outcomes. Surg Endosc 2005;19:1613-7. (Pubitemid 41719530)
    • (2005) Surgical Endoscopy , vol.19 , Issue.12 , pp. 1613-1617
    • Berber, E.1    Ari, E.2    Herceg, N.3    Siperstein, A.4
  • 38
    • 84861606651 scopus 로고    scopus 로고
    • Liver resection for liver metastases from nondigestive endocrine cancer: Extrahepatic disease burden defines outcome
    • Andreou A, Brouquet A, Bharathy KG, Perrier ND, Abdalla EK, Curley SA et al. Liver resection for liver metastases from nondigestive endocrine cancer: extrahepatic disease burden defines outcome. Surgery 2012;151:851-9.
    • (2012) Surgery , vol.151 , pp. 851-859
    • Andreou, A.1    Brouquet, A.2    Bharathy, K.G.3    Perrier, N.D.4    Abdalla, E.K.5    Curley, S.A.6
  • 39
    • 75449115904 scopus 로고    scopus 로고
    • Clinical trials for progressive differentiated thyroid cancer: Patient selection, study design, and recent advances
    • Schlumberger M, Sherman SI. Clinical trials for progressive differentiated thyroid cancer: patient selection, study design, and recent advances. Thyroid 2009;19:1393-400.
    • (2009) Thyroid , vol.19 , pp. 1393-1400
    • Schlumberger, M.1    Sherman, S.I.2
  • 40
    • 79251484686 scopus 로고    scopus 로고
    • Do histological, immunohistochemical, and metabolic (radioiodine and fluorodeoxyglucose uptakes) patterns of metastatic thyroid cancer correlate with patient outcome?
    • Deandreis D, Al Ghuzlan A, Leboulleux S, Lacroix L, Garsi JP, Talbot M et al. Do histological, immunohistochemical, and metabolic (radioiodine and fluorodeoxyglucose uptakes) patterns of metastatic thyroid cancer correlate with patient outcome? Endocrinerelated cancer 2011;18:159-69.
    • (2011) Endocrinerelated Cancer , vol.18 , pp. 159-169
    • Deandreis, D.1    Al Ghuzlan, A.2    Leboulleux, S.3    Lacroix, L.4    Garsi, J.P.5    Talbot, M.6
  • 41
    • 70449370231 scopus 로고    scopus 로고
    • Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer
    • Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, Mandel SJ et al. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 2009;19:1167-214.
    • (2009) Thyroid , vol.19 , pp. 1167-1214
    • Cooper, D.S.1    Doherty, G.M.2    Haugen, B.R.3    Kloos, R.T.4    Lee, S.L.5    Mandel, S.J.6
  • 44
    • 53749086690 scopus 로고    scopus 로고
    • BRAF(V600E) mutation and outcome of patients with papillary thyroid carcinoma: A 15-year median follow-up study
    • Elisei R, Ugolini C, Viola D, Lupi C, Biagini A, Giannini R et al. BRAF(V600E) mutation and outcome of patients with papillary thyroid carcinoma: a 15-year median follow-up study. J Clin Endocrinol Metab 2008;93:3943-9.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 3943-3949
    • Elisei, R.1    Ugolini, C.2    Viola, D.3    Lupi, C.4    Biagini, A.5    Giannini, R.6
  • 45
    • 21244457181 scopus 로고    scopus 로고
    • BRAF mutation in thyroid cancer
    • DOI 10.1677/erc.1.0978
    • Xing M. BRAF mutation in thyroid cancer. Endocr Relat Cancer 2005;12:245-62. (Pubitemid 40896444)
    • (2005) Endocrine-Related Cancer , vol.12 , Issue.2 , pp. 245-262
    • Xing, M.1
  • 48
    • 33747369828 scopus 로고    scopus 로고
    • The BRAF mutation is useful for prediction of clinical recurrence in low-risk patients with conventional papillary thyroid carcinoma
    • Oxf
    • Kim TY, Kim WB, Rhee YS, Song JY, Kim JM, Gong G et al. The BRAF mutation is useful for prediction of clinical recurrence in low-risk patients with conventional papillary thyroid carcinoma. Clin Endocrinol (Oxf) 2006;65:364-8.
    • (2006) Clin Endocrinol , vol.65 , pp. 364-368
    • Kim, T.Y.1    Kim, W.B.2    Rhee, Y.S.3    Song, J.Y.4    Kim, J.M.5    Gong, G.6
  • 51
    • 33645964942 scopus 로고    scopus 로고
    • The oncogene BRAF V600E is associated with a high risk of recurrence and less differentiated papillary thyroid carcinoma due to the impairment of Na+/I- targeting to the membrane
    • Riesco-Eizaguirre G, Gutierrez-Martinez P, Garcia-Cabezas MA, Nistal M, Santisteban P. The oncogene BRAF V600E is associated with a high risk of recurrence and less differentiated papillary thyroid carcinoma due to the impairment of Na+/I- targeting to the membrane. Endocr Relat Cancer 2006;13:257-69.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 257-269
    • Riesco-Eizaguirre, G.1    Gutierrez-Martinez, P.2    Garcia-Cabezas, M.A.3    Nistal, M.4    Santisteban, P.5
  • 52
    • 82955233568 scopus 로고    scopus 로고
    • Both BRAF V600E mutation and older age (≥65 years) are associated with recurrent papillary thyroid cancer
    • Howell GM, Carty SE, Armstrong MJ, Lebeau SO, Hodak SP, Coyne C et al. Both BRAF V600E mutation and older age (≥65 years) are associated with recurrent papillary thyroid cancer. Ann Surg Oncol 2011;18:3566-71.
    • (2011) Ann Surg Oncol , vol.18 , pp. 3566-3571
    • Howell, G.M.1    Carty, S.E.2    Armstrong, M.J.3    Lebeau, S.O.4    Hodak, S.P.5    Coyne, C.6
  • 53
    • 84861988936 scopus 로고    scopus 로고
    • Papillary thyroid carcinomas with cervical lymph node metastases can be stratified into clinically relevant prognostic categories using oncogenic BRAF, the number of nodal metastases, and extra-nodal extension
    • Ricarte-Filho J, Ganly I, Rivera M, Katabi N, Fu W, Shaha A et al. Papillary thyroid carcinomas with cervical lymph node metastases can be stratified into clinically relevant prognostic categories using oncogenic BRAF, the number of nodal metastases, and extra-nodal extension. Thyroid 2012;22:575-84.
    • (2012) Thyroid , vol.22 , pp. 575-584
    • Ricarte-Filho, J.1    Ganly, I.2    Rivera, M.3    Katabi, N.4    Fu, W.5    Shaha, A.6
  • 54
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • DOI 10.1038/74651
    • Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 2000;6:389-95. (Pubitemid 30208155)
    • (2000) Nature Medicine , vol.6 , Issue.4 , pp. 389-395
    • Carmeliet, P.1
  • 55
    • 0035034282 scopus 로고    scopus 로고
    • Intensity of vascular endothelial growth factor expression is associated with increased risk of recurrence and decreased disease-free survival in papillary thyroid cancer
    • DOI 10.1067/msy.2001.112592
    • Lennard CM, Patel A, Wilson J, Reinhardt B, Tuman C, Fenton C et al. Intensity of vascular endothelial growth factor expression is associated with increased risk of recurrence and decreased disease-free survival in papillary thyroid cancer. Surgery 2001;129:552-8. (Pubitemid 32374986)
    • (2001) Surgery , vol.129 , Issue.5 , pp. 552-558
    • Lennard, C.M.1    Patel, A.2    Wilson, J.3    Reinhardt, B.4    Tuman, C.5    Fenton, C.6    Blair, E.7    Francis, G.L.8    Tuttle, R.M.9
  • 59
    • 72949106263 scopus 로고    scopus 로고
    • Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma
    • Hoftijzer H, Heemstra KA, Morreau H, Stokkel MP, Corssmit EP, Gelderblom H et al. Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma. Eur J Endocrinol 2009;161:923-31.
    • (2009) Eur J Endocrinol , vol.161 , pp. 923-931
    • Hoftijzer, H.1    Heemstra, K.A.2    Morreau, H.3    Stokkel, M.P.4    Corssmit, E.P.5    Gelderblom, H.6
  • 60
    • 84867527699 scopus 로고    scopus 로고
    • Long term analysis of the efficacy and tolerability of sorafenib in advanced radio-iodine refractory differentiated thyroid carcinoma: Final results of a phase II trial
    • Schneider T, Abdulrahman R, Corssmit EP, Morreau H, Smit JW, Kapiteijn E. Long term analysis of the efficacy and tolerability of sorafenib in advanced radio-iodine refractory differentiated thyroid carcinoma: final results of a phase II trial. Eur J Endocrinol 2012;167:643-50.
    • (2012) Eur J Endocrinol , vol.167 , pp. 643-650
    • Schneider, T.1    Abdulrahman, R.2    Corssmit, E.P.3    Morreau, H.4    Smit, J.W.5    Kapiteijn, E.6
  • 61
    • 79960179069 scopus 로고    scopus 로고
    • Analysis of the efficacy and toxicity of sorafenib in thyroid cancer: A phase II study in a UK based population
    • Ahmed M, Barbachano Y, Riddell A, Hickey J, Newbold KL, Viros A et al. Analysis of the efficacy and toxicity of sorafenib in thyroid cancer: a phase II study in a UK based population. Eur J Endocrinol 2011;165:315-22.
    • (2011) Eur J Endocrinol , vol.165 , pp. 315-322
    • Ahmed, M.1    Barbachano, Y.2    Riddell, A.3    Hickey, J.4    Newbold, K.L.5    Viros, A.6
  • 62
    • 77954476036 scopus 로고    scopus 로고
    • Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: The M. D. Anderson experience
    • Cabanillas ME, Waguespack SG, Bronstein Y, Williams MD, Feng L, Hernandez M et al. Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: the M. D. Anderson experience. J Clin Endocrinol Metab 2010;95:2588-95.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 2588-2595
    • Cabanillas, M.E.1    Waguespack, S.G.2    Bronstein, Y.3    Williams, M.D.4    Feng, L.5    Hernandez, M.6
  • 63
    • 78049462514 scopus 로고    scopus 로고
    • Phase II study of daily sunitinib in FDG-PET-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation
    • Carr LL, Mankoff DA, Goulart BH, Eaton KD, Capell PT, Kell EM et al. Phase II study of daily sunitinib in FDG-PET-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation. Clin Cancer Res 2011;16:5260-8.
    • (2011) Clin Cancer Res , vol.16 , pp. 5260-5268
    • Carr, L.L.1    Mankoff, D.A.2    Goulart, B.H.3    Eaton, K.D.4    Capell, P.T.5    Kell, E.M.6
  • 64
    • 84875289582 scopus 로고    scopus 로고
    • Personal communication
    • Personal communication with Renato Martins ed, 2010.
    • (2010)
    • Martins, R.1
  • 66
    • 65749087602 scopus 로고    scopus 로고
    • Phase 2 study of sunitinib in refractory thyroid cancer
    • abstr 6025
    • Cohen E, Needles B, Cullen K, Wong S, Wade J, Ivy S et al. Phase 2 study of sunitinib in refractory thyroid cancer. J Clin Oncol 2008;26(Suppl): abstr 6025.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Cohen, E.1    Needles, B.2    Cullen, K.3    Wong, S.4    Wade, J.5    Ivy, S.6
  • 67
    • 77957359933 scopus 로고    scopus 로고
    • Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: Results of a phase 2 consortium study
    • Bible KC, Suman VJ, Molina JR, Smallridge RC, Maples WJ, Menefee ME et al. Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study. Lancet Oncol 2011;11:962-72.
    • (2011) Lancet Oncol , vol.11 , pp. 962-972
    • Bible, K.C.1    Suman, V.J.2    Molina, J.R.3    Smallridge, R.C.4    Maples, W.J.5    Menefee, M.E.6
  • 68
    • 84655175698 scopus 로고    scopus 로고
    • Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: A randomized, double-blind phase III trial
    • Wells SA, Jr., Robinson BG, Gagel RF, Dralle H, Fagin JA, Santoro M et al. Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial. J Clin Oncol 2012;30:134-41.
    • (2012) J Clin Oncol , vol.30 , pp. 134-141
    • Wells Jr., S.A.1    Robinson, B.G.2    Gagel, R.F.3    Dralle, H.4    Fagin, J.A.5    Santoro, M.6
  • 69
    • 84865552505 scopus 로고    scopus 로고
    • Vandetanib in locally advanced or metastatic differentiated thyroid cancer: A randomised, double-blind, phase 2 trial
    • Leboulleux S, Bastholt L, Krause T, de la Fouchardiere C, Tennvall J, Awada A et al. Vandetanib in locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 2 trial. Lancet Oncol 2012;13:897-905.
    • (2012) Lancet Oncol , vol.13 , pp. 897-905
    • Leboulleux, S.1    Bastholt, L.2    Krause, T.3    De La Fouchardiere, C.4    Tennvall, J.5    Awada, A.6
  • 71
    • 24944453855 scopus 로고    scopus 로고
    • Phase I trial of the oral antiangiogenesis agent AG-013736 in patients with advanced solid tumors: Pharmacokinetic and clinical results
    • Rugo HS, Herbst RS, Liu G, Park JW, Kies MS, Steinfeldt HM et al. Phase I trial of the oral antiangiogenesis agent AG-013736 in patients with advanced solid tumors: pharmacokinetic and clinical results. J Clin Oncol 2005;23:5474-83.
    • (2005) J Clin Oncol , vol.23 , pp. 5474-5483
    • Rugo, H.S.1    Herbst, R.S.2    Liu, G.3    Park, J.W.4    Kies, M.S.5    Steinfeldt, H.M.6
  • 72
    • 50649095801 scopus 로고    scopus 로고
    • Axitinib is an active treatment for all histologic subtypes of advanced thyroid cancer: Results from a phase II study
    • Cohen EE, Rosen LS, Vokes EE, Kies MS, Forastiere AA, Worden FP et al. Axitinib is an active treatment for all histologic subtypes of advanced thyroid cancer: results from a phase II study. J Clin Oncol 2008;26:4708-13.
    • (2008) J Clin Oncol , vol.26 , pp. 4708-4713
    • Cohen, E.E.1    Rosen, L.S.2    Vokes, E.E.3    Kies, M.S.4    Forastiere, A.A.5    Worden, F.P.6
  • 75
    • 77957366667 scopus 로고    scopus 로고
    • Biomarkers as predictors of response to treatment with motesanib in patients with progressive advanced thyroid cancer
    • Bass MB, Sherman SI, Schlumberger MJ, Davis MT, Kivman L, Khoo HM et al. Biomarkers as predictors of response to treatment with motesanib in patients with progressive advanced thyroid cancer. J Clin Endocrinol Metab 2010;95:5018-27.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 5018-5027
    • Bass, M.B.1    Sherman, S.I.2    Schlumberger, M.J.3    Davis, M.T.4    Kivman, L.5    Khoo, H.M.6
  • 76
    • 84859410770 scopus 로고    scopus 로고
    • Phase II efficacy and pharmacogenomic study of Selumetinib (AZD6244; ARRY-142886) in iodine-131 refractory papillary thyroid carcinoma with or without follicular elements
    • Hayes DN, Lucas AS, Tanvetyanon T, Krzyzanowska MK, Chung CH, Murphy BA et al. Phase II efficacy and pharmacogenomic study of Selumetinib (AZD6244; ARRY-142886) in iodine-131 refractory papillary thyroid carcinoma with or without follicular elements. Clin Cancer Res 2012;18:2056-65.
    • (2012) Clin Cancer Res , vol.18 , pp. 2056-2065
    • Hayes, D.N.1    Lucas, A.S.2    Tanvetyanon, T.3    Krzyzanowska, M.K.4    Chung, C.H.5    Murphy, B.A.6
  • 77
    • 84875151746 scopus 로고    scopus 로고
    • Antitumor activity of cabozantinib (XL184) in a cohort of patients (pts) with differentiated thyroid cancer (DTC)
    • abstr 5547
    • Cabanillas ME, Brose MS, Lee Y, Miles D, Sherman SI. Antitumor activity of cabozantinib (XL184) in a cohort of patients (pts) with differentiated thyroid cancer (DTC). J Clin Oncol 2012;30(Suppl):abstr 5547.
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL.
    • Cabanillas, M.E.1    Brose, M.S.2    Lee, Y.3    Miles, D.4    Sherman, S.I.5
  • 78
    • 80053160399 scopus 로고    scopus 로고
    • A phase II trial of the multitargeted kinase inhibitor E7080 in advanced radioiodine (RAI)-refractory differentiated thyroid cancer (DTC)
    • abstr 5503
    • Sherman SI, Jarzab B, Cabanillas ME, Licitra L, Pacini F, Martins R et al. A phase II trial of the multitargeted kinase inhibitor E7080 in advanced radioiodine (RAI)-refractory differentiated thyroid cancer (DTC). J Clin Oncol 2011;29(Suppl):abstr 5503.
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL.
    • Sherman, S.I.1    Jarzab, B.2    Cabanillas, M.E.3    Licitra, L.4    Pacini, F.5    Martins, R.6
  • 79
    • 84861083983 scopus 로고    scopus 로고
    • Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: A phase 1 dose-escalation trial
    • Falchook GS, Long GV, Kurzrock R, Kim KB, Arkenau TH, Brown MP et al. Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. Lancet 2012;379:1893-901.
    • (2012) Lancet , vol.379 , pp. 1893-1901
    • Falchook, G.S.1    Long, G.V.2    Kurzrock, R.3    Kim, K.B.4    Arkenau, T.H.5    Brown, M.P.6
  • 80
    • 79953904634 scopus 로고    scopus 로고
    • Inhibition of the Ras/Raf/MEK/ERK and RET kinase pathways with the combination of the multikinase inhibitor sorafenib and the farnesyltransferase inhibitor tipifarnib in medullary and differentiated thyroid malignancies
    • Hong DS, Cabanillas ME, Wheler J, Naing A, Tsimberidou AM, Ye L et al. Inhibition of the Ras/Raf/MEK/ERK and RET kinase pathways with the combination of the multikinase inhibitor sorafenib and the farnesyltransferase inhibitor tipifarnib in medullary and differentiated thyroid malignancies. J Clin Endocrinol Metab 2011;96:997-1005.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 997-1005
    • Hong, D.S.1    Cabanillas, M.E.2    Wheler, J.3    Naing, A.4    Tsimberidou, A.M.5    Ye, L.6
  • 81
    • 84866775134 scopus 로고    scopus 로고
    • A phase II study of temsirolimus/sorafenib in patients with radioactive iodine (RAI)-refractory thyroid carcinoma
    • abstr 5514
    • Sherman E, Ho AL, Fury M, Baxi SS, Haque S, Korte SH et al. A phase II study of temsirolimus/sorafenib in patients with radioactive iodine (RAI)-refractory thyroid carcinoma. J Clin Oncol 2012;30(Suppl):abstr 5514.
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL.
    • Sherman, E.1    Ho, A.L.2    Fury, M.3    Baxi, S.S.4    Haque, S.5    Korte, S.H.6
  • 82
    • 62849099971 scopus 로고    scopus 로고
    • Sunitinib treatment for patients with advanced clear-cell renal-cell carcinoma after progression on sorafenib
    • Zimmermann K, Schmittel A, Steiner U, Asemissen AM, Knoedler M, Thiel E et al. Sunitinib treatment for patients with advanced clear-cell renal-cell carcinoma after progression on sorafenib. Oncology 2009;76:350-4.
    • (2009) Oncology , vol.76 , pp. 350-354
    • Zimmermann, K.1    Schmittel, A.2    Steiner, U.3    Asemissen, A.M.4    Knoedler, M.5    Thiel, E.6
  • 85
    • 34248351866 scopus 로고    scopus 로고
    • A phase II study of single agent depsipeptide (DEP) in patients (pts) with radioactive iodine (RAI)-refractory, metastatic, thyroid carcinoma: Preliminary toxicity and efficacy experience
    • abstr 5554
    • Su YB, Tuttle RM, Fury M, Ghossein R, Singh B, Herman K et al. A phase II study of single agent depsipeptide (DEP) in patients (pts) with radioactive iodine (RAI)-refractory, metastatic, thyroid carcinoma: Preliminary toxicity and efficacy experience. J Clin Oncol 2006;24(Suppl):abstr 5554.
    • (2006) J Clin Oncol , vol.24 , Issue.SUPPL.
    • Su, Y.B.1    Tuttle, R.M.2    Fury, M.3    Ghossein, R.4    Singh, B.5    Herman, K.6
  • 86
    • 33845561938 scopus 로고    scopus 로고
    • A phase II trial of rosiglitazone in patients with thyroglobulin-positive and radioiodine-negative differentiated thyroid cancer
    • discussion 66-7
    • Kebebew E, Peng M, Reiff E, Treseler P, Woeber KA, Clark OH et al. A phase II trial of rosiglitazone in patients with thyroglobulin-positive and radioiodine-negative differentiated thyroid cancer. Surgery 2006;140:960-6; discussion 66-7.
    • (2006) Surgery , vol.140 , pp. 960-966
    • Kebebew, E.1    Peng, M.2    Reiff, E.3    Treseler, P.4    Woeber, K.A.5    Clark, O.H.6
  • 87
    • 84055191090 scopus 로고    scopus 로고
    • Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation
    • Chakravarty D, Santos E, Ryder M, Knauf JA, Liao XH, West BL et al. Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation. J Clin Invest 2011;121):4700-11.
    • (2011) J Clin Invest , vol.121 , pp. 4700-4711
    • Chakravarty, D.1    Santos, E.2    Ryder, M.3    Knauf, J.A.4    Liao, X.H.5    West, B.L.6
  • 88
    • 84866756710 scopus 로고    scopus 로고
    • Reacquisition of RAI uptake in RAI-refractory metastatic thyroid cancers by pretreatment with the MEK inhibitor selumetinib
    • abstr 5509
    • Ho L, Leboeuf R, Grewal RK, Sherman EJ, Deandreis D, Pentlow K et al. Reacquisition of RAI uptake in RAI-refractory metastatic thyroid cancers by pretreatment with the MEK inhibitor selumetinib. J Clin Oncol 2012;30(Suppl):abstr 5509.
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL.
    • Ho, L.1    Leboeuf, R.2    Grewal, R.K.3    Sherman, E.J.4    Deandreis, D.5    Pentlow, K.6
  • 89
    • 84861968322 scopus 로고    scopus 로고
    • Programmed death-1+ T cells and regulatory T cells are enriched in tumor-involved lymph nodes and associated with aggressive features in papillary thyroid cancer
    • French JD, Kotnis GR, Said S, Raeburn CD, McIntyre RC, Jr., Klopper JP et al. Programmed death-1+ T cells and regulatory T cells are enriched in tumor-involved lymph nodes and associated with aggressive features in papillary thyroid cancer. J Clin Endocrinol Metab 2012;97:E934-43.
    • (2012) J Clin Endocrinol Metab , vol.97
    • French, J.D.1    Kotnis, G.R.2    Said, S.3    Raeburn, C.D.4    McIntyre Jr., R.C.5    Klopper, J.P.6
  • 90
    • 77952778924 scopus 로고    scopus 로고
    • Tumor-associated lymphocytes and increased FoxP3+ regulatory T cell frequency correlate with more aggressive papillary thyroid cancer
    • French JD, Weber ZJ, Fretwell DL, Said S, Klopper JP, Haugen BR. Tumor-associated lymphocytes and increased FoxP3+ regulatory T cell frequency correlate with more aggressive papillary thyroid cancer. J Clin Endocrinol Metab 2010;95:2325-33.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 2325-2333
    • French, J.D.1    Weber, Z.J.2    Fretwell, D.L.3    Said, S.4    Klopper, J.P.5    Haugen, B.R.6
  • 91
    • 84861778428 scopus 로고    scopus 로고
    • Challenges associated with tyrosine kinase inhibitor therapy for metastatic thyroid cancer
    • Cabanillas ME, Hu MI, Durand JB, Busaidy NL. Challenges associated with tyrosine kinase inhibitor therapy for metastatic thyroid cancer. J Thyroid Res 2011;2011:985780.
    • (2011) J Thyroid Res , vol.2011 , pp. 985780
    • Cabanillas, M.E.1    Hu, M.I.2    Durand, J.B.3    Busaidy, N.L.4
  • 92
    • 84870340425 scopus 로고    scopus 로고
    • Differentiated thyroid cancer: Management of patients with radioiodine nonresponsive disease
    • Busaidy NL, Cabanillas ME. Differentiated thyroid cancer: management of patients with radioiodine nonresponsive disease. J Thyroid Res 2012;2012:618985.
    • (2012) J Thyroid Res , vol.2012 , pp. 618985
    • Busaidy, N.L.1    Cabanillas, M.E.2
  • 93
    • 75549086941 scopus 로고    scopus 로고
    • Molecularly targeted therapies for thyroid cancers
    • Sherman SI. Molecularly targeted therapies for thyroid cancers. Endocr Pract 2009;15:605-11.
    • (2009) Endocr Pract , vol.15 , pp. 605-611
    • Sherman, S.I.1
  • 94
    • 84870340425 scopus 로고    scopus 로고
    • Differentiated thyroid cancer: Management of patients with radioiodine nonresponsive disease
    • Busaidy NL, Cabanillas ME. Differentiated thyroid cancer: management of patients with radioiodine nonresponsive disease. J Thyroid Res 2012;2012:618985.
    • (2012) J Thyroid Res , vol.2012 , pp. 618985
    • Busaidy, N.L.1    Cabanillas, M.E.2
  • 95
    • 39049095199 scopus 로고    scopus 로고
    • Pazopanib, a potent orally administered small-molecule multitargeted tyrosine kinase inhibitor for renal cell carcinoma
    • DOI 10.1517/13543784.17.2.253
    • Sonpavde G, Hutson TE, Sternberg CN. Pazopanib, a potent orally administered small-molecule multitargeted tyrosine kinase inhibitor for renal cell carcinoma. Expert Opin Investig Drugs 2008;17:253-61. (Pubitemid 351578205)
    • (2008) Expert Opinion on Investigational Drugs , vol.17 , Issue.2 , pp. 253-261
    • Sonpavde, G.1    Hutson, T.E.2    Sternberg, C.N.3
  • 96
    • 53049085556 scopus 로고    scopus 로고
    • Multi-kinase inhibitor E7080 suppresses lymph node and lung metastases of human mammary breast tumor MDA-MB-231 via inhibition of vascular endothelial growth factor-receptor (VEGF-R) 2 and VEGF-R3 kinase
    • Matsui J, Funahashi Y, Uenaka T, Watanabe T, Tsuruoka A, Asada M. Multi-kinase inhibitor E7080 suppresses lymph node and lung metastases of human mammary breast tumor MDA-MB-231 via inhibition of vascular endothelial growth factor-receptor (VEGF-R) 2 and VEGF-R3 kinase. Clin Cancer Res 2008;14:5459-65.
    • (2008) Clin Cancer Res , vol.14 , pp. 5459-5465
    • Matsui, J.1    Funahashi, Y.2    Uenaka, T.3    Watanabe, T.4    Tsuruoka, A.5    Asada, M.6
  • 97
    • 37349105704 scopus 로고    scopus 로고
    • E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition
    • DOI 10.1002/ijc.23131
    • Matsui J, Yamamoto Y, Funahashi Y, Tsuruoka A, Watanabe T, Wakabayashi T et al. E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition. Int J Cancer 2008;122:664-71. (Pubitemid 350308963)
    • (2008) International Journal of Cancer , vol.122 , Issue.3 , pp. 664-671
    • Matsui, J.1    Yamamoto, Y.2    Funahashi, Y.3    Tsuruoka, A.4    Watanabe, T.5    Wakabayashi, T.6    Uenaka, T.7    Asada, M.8
  • 98
    • 83355166909 scopus 로고    scopus 로고
    • Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth
    • Yakes FM, Chen J, Tan J, Yamaguchi K, Shi Y, Yu P et al. Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. Mol Cancer Ther 2011;10:2298-308.
    • (2011) Mol Cancer Ther , vol.10 , pp. 2298-2308
    • Yakes, F.M.1    Chen, J.2    Tan, J.3    Yamaguchi, K.4    Shi, Y.5    Yu, P.6


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