68Ga-DOTATATE PET/CT for the detection of inflammation of large arteries: Correlation with 18F-FDG, calcium burden and risk factors

EJNMMI Research

Volumn 2, Issue 1, 2012, Pages 1-10

  Li, Xiang ^a   Samnick, Samuel ^a,b   Lapa, Constantin ^a   Israel, Ina ^a   Buck, Andreas K ^a,b   Kreissl, Michael C ^a,b   Bauer, Wolfgang ^a,b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

Author keywords

Atherosclerotic plaque; Cardiovascular risk factors; Macrophage; Somatostatin receptor

Indexed keywords

ANTINEOPLASTIC AGENT; CALCIUM; CAPECITABINE; CISPLATIN; ETOPOSIDE; FLUORODEOXYGLUCOSE F 18; OCTREOTATE[DEXTRO PHENYLTYROSINE TETRAXETAN]GA 68; OCTREOTATE[DEXTRO PHENYLTYROSINE TETRAXETAN]LU 177; OCTREOTIDE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ADULT; AGE DISTRIBUTION; AGED; ANALYTICAL PARAMETERS; ARTERY CALCIFICATION; ARTICLE; ATHEROSCLEROSIS; CALCIUM TRANSPORT; CANCER HORMONE THERAPY; CANCER STAGING; CARCINOID; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CLINICAL ARTICLE; CLINICAL ASSESSMENT; COMPUTED TOMOGRAPHY SCANNER; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CORRELATION COEFFICIENT; DRUG ACCUMULATION; DRUG DISTRIBUTION; DRUG UPTAKE; ESOPHAGUS CANCER; FEMALE; GREAT BLOOD VESSEL; HIGH RISK POPULATION; HUMAN; HYPERTENSION; IMAGE ANALYSIS; LOW RISK POPULATION; MALE; NEUROENDOCRINE TUMOR; PILOT STUDY; PRIORITY JOURNAL; RECTUM CARCINOID; RETROSPECTIVE STUDY; RISK ASSESSMENT; SINGLE DRUG DOSE; STOMACH CANCER; TARGET TO BACKGROUND RATIO; THYROID CANCER;

EID: 84875295401     PISSN: None     EISSN: 2191219X     Source Type: Journal    
DOI: 10.1186/2191-219X-2-52     Document Type: Article

References (33)

1. Williams KJ, Tabas I: Atherosclerosis-an inflammatory disease. N Engl J Med 1999, 340(24):1928. author reply 1929.
2. Yusuf S, Reddy S, Ounpuu S, Anand S: Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization. Circulation 2001, 104(22):2746-2753.
3. Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, Rumberger J, Badimon JJ, Stefanadis C, Moreno P, Pasterkamp G, Fayad Z, Stone PH, Waxman S, Raggi P, Madjid M, Zarrabi A, Burke A, Yuan C, Fitzgerald PJ, Siscovick DS, de Korte CL, Aikawa M, Airaksinen KEJ, Assmann G, Becker CR, Chesebro JH, Farb A, Galis ZS, Jackson C, Jang I-K: From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: part I. Circulation 2003, 108(14):1664-1672.
4. Ross R: Atherosclerosis-an inflammatory disease. N Engl J Med 1999, 340(2):115-126.
5. Hansson GK: Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005, 352(16):1685-1695.
6. Guedes A, Tardif JC: Intravascular ultrasound assessment of atherosclerosis. Curr Atheroscler Rep 2004, 6(3):219-224.
7. Tearney GJ, Jang IK, Bouma BE: Optical coherence tomography for imaging the vulnerable plaque. J Biomed Opt 2006, 11(2):021002.
8. Voros S, Rinehart S, Qian Z, Joshi P, Vazquez G, Fischer C, Belur P, Hulten E, Villines TC: Coronary atherosclerosis imaging by coronary CT angiography: current status, correlation with intravascular interrogation and meta-analysis. JACC Cardiovasc Imaging 2011, 4(5):537-548.
9. Kooi ME, Cappendijk VC, Cleutjens KB, Kessels AG, Kitslaar PJ, Borgers M, Frederik PM, Daemen MJ, van Engelshoven JM: Accumulation of ultrasmall superparamagnetic particles of iron oxide in human atherosclerotic plaques can be detected by in vivo magnetic resonance imaging. Circulation 2003, 107(19):2453-2458.
10. Kaufmann BA, Sanders JM, Davis C, Xie A, Aldred P, Sarembock IJ, Lindner JR: Molecular imaging of inflammation in atherosclerosis with targeted ultrasound detection of vascular cell adhesion molecule-1. Circulation 2007, 116(3):276-284.
11. Schafers M, Riemann B, Kopka K, Breyholz HJ, Wagner S, Schäfers KP, Law MP, Schober O, Levkau B: Scintigraphic imaging of matrix metalloproteinase activity in the arterial wall in vivo. Circulation 2004, 109(21):2554-2559.
12. Razansky D, Harlaar NJ, Hillebrands JL, Taruttis A, Herzog E, Zeebregts CJ, van Dam GM, Ntziachristos V: Multispectral optoacoustic tomography of matrix metalloproteinase activity in vulnerable human carotid plaques. Mol Imaging Biol 2012, 14(3):277-285.
13. Krantic S: Peptides as regulators of the immune system: emphasis on somatostatin. Peptides 2000, 21(12):1941-1964.
14. Dalm VA, van Hagen PM, van Koetsveld PM, Achilefu S, Houtsmuller AB, Pols DH, van der Lely AJ, Lamberts SW, Hofland LJ: Expression of somatostatin, cortistatin, and somatostatin receptors in human monocytes, macrophages, and dendritic cells. American Am J Physiol Endocrinol Metab 2003, 285(2):E344-E353.
15. Armani C, Catalani E, Balbarini A, Bagnoli P, Cervia D: Expression, pharmacology, and functional role of somatostatin receptor subtypes 1 and 2 in human macrophages. J Leukoc Biol 2007, 81(3):845-855.
16. Rominger A, Saam T, Vogl E, Ubleis C, la Fougère C, Förster S, Haug A, Cumming P, Reiser MF, Nikolaou K, Bartenstein P, Hacker M: In vivo imaging of macrophage activity in the coronary arteries using 68Ga-DOTATATE PET/CT: correlation with coronary calcium burden and risk factors. J Nucl Med 2010, 51(2):193-197.
17. Ben-Haim S, Kupzov E, Tamir A, Israel O: Evaluation of 18F-FDG uptake and arterial wall calcifications using 18F-FDG PET/CT. J Nucl Med 2004, 45(11):1816-1821.
18. Dunphy MP, Freiman A, Larson SM, Strauss HW: Association of vascular 18F-FDG uptake with vascular calcification. J Nucl Med 2005, 46(8): 1278-1284.
19. Wu YW, Kao HL, Chen MF, Lee BC, Tseng WY, Jeng JS, Tzen KY, Yen RF, Huang PJ, Yang WS: Characterization of plaques using 18F-FDG PET/CT in patients with carotid atherosclerosis and correlation with matrix metalloproteinase-1. J Nucl Med 2007, 48(2):227-233.
20. Rudd JH, Warburton EA, Fryer TD, Jones HA, Clark JC, Antoun N, Johnström P, Davenport AP, Kirkpatrick PJ, Arch BN, Pickard JD, Weissberg PL: Imaging atherosclerotic plaque inflammation with [18F]-fluorodeoxyglucose positron emission tomography. Circulation 2002, 105(23):2708-2711.
21. Tawakol A, Migrino RQ, Bashian GG, Bedri S, Vermylen D, Cury RC, Yates D, LaMuraglia GM, Furie K, Houser S, Gewirtz H, Muller JE, Brady TJ, Fischman AJ: In vivo 18F-fluorodeoxyglucose positron emission tomography imaging provides a noninvasive measure of carotid plaque inflammation in patients. JACC 2006, 48(9):1818-1824.
22. Saam T, Rominger A, Wolpers S, Nikolaou K, Rist C, Greif M, Cumming P, Becker A, Foerster S, Reiser MF, Bartenstein P, Hacker M: Association of inflammation of the left anterior descending coronary artery with cardiovascular risk factors, plaque burden and pericardial fat volume: a PET/CT study. Eur J Nucl Med Mol Imaging 2010, 37(6):1203-1212.
23. Kato K, Schober O, Ikeda M, Schäfers M, Ishigaki T, Kies P, Naganawa S, Stegger L: Evaluation and comparison of 11C-choline uptake and calcification in aortic and common carotid arterial walls with combined PET/CT. Eur J Nucl Med Mol Imaging 2009, 36(10):1622-1628.
24. Yun M, Jang S, Cucchiara A, Newberg AB, Alavi A: 18F FDG uptake in the large arteries: a correlation study with the atherogenic risk factors. Sem Nucl Med 2002, 32(1):70-76.
25. Deichen JT, Prante O, Gack M, Schmiedehausen K, Kuwert T: Uptake of [18F]fluorodeoxyglucose in human monocyte-macrophages in vitro. Eur J Nucl Med Mol Imaging 2003, 30(2):267-273.
26. Yan S, Li M, Chai H, Yang H, Lin PH, Yao Q, Chen C: TNF-alpha decreases expression of somatostatin, somatostatin receptors, and cortistatin in human coronary endothelial cells. J Surg Res 2005, 123(2):294-301.
27. Agatston AS, Janowitz WR, Hildner FJ, Zusmer NR, Viamonte M Jr: Detrano R: Quantification of coronary artery calcium using ultrafast computed tomography. JACC 1990, 15(4):827-832.
28. Schlosser T, Hunold P, Schmermund A, Kühl H, Waltering KU, Debatin JF, Barkhausen J: Coronary artery calcium score: influence of reconstruction interval at 16-detector row CT with retrospective electrocardiographic gating. Radiology 2004, 233(2):586-589.
29. Forster S, Rominger A, Saam T, Wolpers S, Nikolaou K, Cumming P, Reiser MF, Bartenstein P, Hacker M: 18F-fluoroethylcholine uptake in arterial vessel walls and cardiovascular risk factors: correlation in a PET-CT study. Nuklearmedizin 2010, 49(4):148-153.
30. Rudd JH, Myers KS, Bansilal S, Machac J, Pinto CA, Tong C, Rafique A, Hargeaves R, Farkouh M, Fuster V, Fayad ZA: Atherosclerosis inflammation imaging with 18F-FDG PET: carotid, iliac, and femoral uptake reproducibility, quantification methods, and recommendations. J Nucl Med 2008, 49(6):871-878.
31. Rominger A, Saam T, Wolpers S, Cyran CC, Schmidt M, Foerster S, Nikolaou K, Reiser MF, Bartenstein P, Hacker M: 18F-FDG PET/CT identifies patients at risk for future vascular events in an otherwise asymptomatic cohort with neoplastic disease. J Nucl Med 2009, 50(10):1611-1620.
32. Adams RL, Adams IO, Lindow SW, Zhong W, Atkin SL: Somatostatin receptors 2 and 5 are preferentially expressed in proliferating endothelium. Br J Cancer 2005, 92(8):1493-1498.
33. McCarthy MJ, Loftus IM, Thompson MM, Jones L, London NJ, Bell PR, Naylor AR, Brindle NP: Angiogenesis and the atherosclerotic carotid plaque: an association between symptomatology and plaque morphology. J Vasc Surgery 1999, 30(2):261-268.