Immune signalling responses in intestinal epithelial cells exposed to pathogenic Escherichia coli and lactic acid-producing probiotics

Beneficial Microbes

Volumn 4, Issue 2, 2013, Pages 195-209

  Ho, N K ^a,b   Hawley, S P ^b   Ossa, J C ^b   Mathieu, O ^c   Tompkins, T A ^c   Johnson Henry, K C ^b   Sherman, P M ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c LALLEMAND SAS   (France)

Author keywords

Epithelia; Gene expression; Immune; Microarray; pathogen; Probiotics

Indexed keywords

PROBIOTIC AGENT;

ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CONTROLLED STUDY; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GROWTH RATE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOREACTIVITY; INNATE IMMUNITY; INTESTINE EPITHELIUM CELL; LACTOBACILLUS HELVETICUS; LACTOBACILLUS RHAMNOSUS; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TISSUE CULTURE CELL;

EID: 84875278636     PISSN: 18762883     EISSN: 18762891     Source Type: Journal    
DOI: 10.3920/BM2012.0038     Document Type: Article

References (33)

1. Alemka, A., Clyne, M., Shanahan, F., Tompkins, T., Corcionivoschi, N. and Bourke, B., 2010. Probiotic colonization of the adherent mucus layer of HT29MTXE12 cells attenuates Campylobacter jejuni virulence properties. Infection and Immunity 78: 2812-2822.
2. Coconnier, M.H., Bernet, M.F., Kerneis, S., Chauviere, G., Fourniat, J. and Servin, A.L., 1993. Inhibition of adhesion of enteroinvasive pathogens to human intestinal Caco-2 cells by Lactobacillus acidophilus strain LB decreases bacterial invasion. FEMS Microbiology Letters 110: 299-305.
3. Croxen, M.A. and Finlay, B.B., 2010. Molecular mechanisms of Escherichia coli pathogenicity. Nature Reviews Microbiology 8: 26-38.
4. Cui, W., Taub, D.D. and Gardner, K., 2007. qPrimerDepot: a primer database for quantitative real time PCR. Nucleic Acids Research 35: D805-809.
5. Dalpke, A.H., Eckerle, S., Frey, M. and Heeg, K., 2003. Triggering of Toll-like receptors modulates IFN-gamma signaling: involvement of serine 727 STAT1 phosphorylation and suppressors of cytokine signaling. European Journal of Immunology 33: 1776-1787.
6. Darfeuille-Michaud, A., Neut, C., Barnich, N., Lederman, E., Di Martino, P., Desreumaux, P., Gambiez, L., Joly, B., Cortot, A. and Colombel, J.F., 1998. Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease. Gastroenterology 115: 1405-1413.
7. Donato, K.A., Gareau, M.G., Wang, Y.J. and Sherman, P.M., 2010. Lactobacillus rhamnosus GG attenuates interferon-{gamma} and tumour necrosis factor-alpha-induced barrier dysfunction and proinflammatory signalling. Microbiology 156: 3288-3297.
8. Dundas, S., Todd, W.T., Stewart, A.I., Murdoch, P.S., Chaudhuri, A.K. and Hutchinson, S.J., 2001. The central Scotland Escherichia coli O157:H7 outbreak: risk factors for the hemolytic uremic syndrome and death among hospitalized patients. Clinical Infectious Diseases 33: 923-931.
9. DuPont, H.L., 2009. Clinical practice. Bacterial diarrhea. The New England Journal of Medicine 361: 1560-1569.
10. Dydensborg, A.B., Herring, E., Auclair, J., Tremblay, E. and Beaulieu, J.F., 2006. Normalizing genes for quantitative RT-PCR in differentiating human intestinal epithelial cells and adenocarcinomas of the colon. American Journal of Physiology - Gastrointestinal and Liver Physiology 290: G1067-G1074.
11. Foster, L.M., Tompkins, T.A. and Dahl, W.J., 2011. A comprehensive post-market review of studies on a probiotic product containing Lactobacillus helveticus R0052 and Lactobacillus rhamnosus R0011. Beneficial Microbes 2: 319-334.
12. Fukata, M., Hernandez, Y., Conduah, D., Cohen, J., Chen, A., Breglio, K., Goo, T., Hsu, D., Xu, R. and Abreu, M.T., 2009. Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors. Inflammatory Bowel Diseases 15: 997-1006.
13. Gareau, M.G., Ho, N.K., Brenner, D., Sousa, A.J., Lebourhis, L., Mak, T.W., Girardin, S.E., Philpott, D.J. and Sherman, P.M., 2011. Enterohaemorrhagic, but not enteropathogenic, Escherichia coli infection of epithelial cells disrupts signalling responses to tumour necrosis factor-alpha. Microbiology 157: 2963-2973.
14. Gareau, M.G., Sherman, P.M. and Walker, W.A., 2010. Probiotics and the gut microbiota in intestinal health and disease. Nature Reviews Gastroenterology and Hepatology 7: 503-514.
15. Gill, H.S., Shu, Q., Lin, H., Rutherfurd, K.J. and Cross, M.L., 2001. Protection against translocating Salmonella typhimurium infection in mice by feeding the immuno-enhancing probiotic Lactobacillus rhamnosus strain HN001. Medical Microbiology and Immunology 190: 97-104.
16. Grzeskowiak, L., Isolauri, E., Salminen, S. and Gueimonde, M., 2011. Manufacturing process influences properties of probiotic bacteria. British Journal of Nutrition 105: 887-894.
17. Hooper, L.V. and Macpherson, A.J., 2010. Immune adaptations that maintain homeostasis with the intestinal microbiota. Nature Reviews Immunology 10: 159-169.
18. Jandu, N., Zeng, Z.J., Johnson-Henry, K.C. and Sherman, P.M., 2009. Probiotics prevent enterohaemorrhagic Escherichia coli O157:H7- mediated inhibition of interferon-gamma-induced tyrosine phosphorylation of STAT-1. Microbiology 155: 531-540.
19. Johnson-Henry, K.C., Donato, K.A., Shen-Tu, G., Gordanpour, M. and Sherman, P.M., 2008. Lactobacillus rhamnosus strain GG prevents enterohemorrhagic Escherichia coli O157:H7-induced changes in epithelial barrier function. Infection and Immunity 76: 1340-1348.
20. Kanehisa, M. and Goto, S., 2000. KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Research 28: 27-30.
21. Kim, Y.H. and Pollack, J.R., 2009. Comparative genomic hybridization on spotted oligonucleotide microarrays. Methods in Molecular Biology 556: 21-32.
22. Marquis, J.F., Nantel, A., LaCourse, R., Ryan, L., North, R.J. and Gros, P., 2008. Fibrotic response as a distinguishing feature of resistance and susceptibility to pulmonary infection with Mycobacterium tuberculosis in mice. Infection and Immunity 76: 78-88.
23. Peterson, M.D. and Mooseker, M.S., 1992. Characterization of the enterocyte-like brush border cytoskeleton of the C2BBe clones of the human intestinal cell line, Caco-2. Journal of Cell Science 102 Part 3: 581-600.
24. Resta-Lenert, S. and Barrett, K.E., 2006. Probiotics and commensals reverse TNF-alpha- and IFN-gamma-induced dysfunction in human intestinal epithelial cells. Gastroenterology 130: 731-746.
25. Rodrigues, D.M., Sousa, A.J., Johnson-Henry, K.C., Sherman, P.M. and Gareau, M.G., 2012. Probiotics are effective for the prevention and treatment of Citrobacter rodentium-induced colitis in mice. Journal of Infectious Diseases 206: 99-109.
26. Saeed, A.I., Sharov, V., White, J., Li, J., Liang, W., Bhagabati, N., Braisted, J., Klapa, M., Currier, T., Thiagarajan, M., Sturn, A., Snuffin, M., Rezantsev, A., Popov, D., Ryltsov, A., Kostukovich, E., Borisovsky, I., Liu, Z., Vinsavich, A., Trush, V. and Quackenbush, J., 2003. TM4: a free, open-source system for microarray data management and analysis. BioTechniques 34: 374-378.
27. Shang, L., Fukata, M., Thirunarayanan, N., Martin, A.P., Arnaboldi, P., Maussang, D., Berin, C., Unkeless, J.C., Mayer, L., Abreu, M.T. and Lira, S.A., 2008. Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria. Gastroenterology 135: 529-538.
28. Sherman, P.M., Johnson-Henry, K.C., Yeung, H.P., Ngo, P.S., Goulet, J. and Tompkins, T.A., 2005. Probiotics reduce enterohemorrhagic Escherichia coli O157:H7- and enteropathogenic E. coli O127:H6- induced changes in polarized T84 epithelial cell monolayers by reducing bacterial adhesion and cytoskeletal rearrangements. Infection and Immunity 73: 5183-5188.
29. Sherman, P.M., Ossa, J.C. and Johnson-Henry, K., 2009. Unraveling mechanisms of action of probiotics. Nutrition in Clinical Practice 24: 10-14.
30. Taylor, S., Wakem, M., Dijkman, G., Alsarraj, M. and Nguyen, M., 2010. A practical approach to RT-qPCR-Publishing data that conform to the MIQE guidelines. Methods 50: S1-5.
31. Tien, M.T., Girardin, S.E., Regnault, B., Le Bourhis, L., Dillies, M.A., Coppee, J.Y., Bourdet-Sicard, R., Sansonetti, P.J. and Pedron, T., 2006. Anti-inflammatory effect of Lactobacillus casei on Shigellainfected human intestinal epithelial cells. Journal of Immunology 176: 1228-1237.
32. Wine, E., Gareau, M.G., Johnson-Henry, K. and Sherman, P.M., 2009. Strain-specific probiotic (Lactobacillus helveticus) inhibition of Campylobacter jejuni invasion of human intestinal epithelial cells. FEMS Microbiology Letters 300: 146-152.
33. Wong, C.S., Jelacic, S., Habeeb, R.L., Watkins, S.L. and Tarr, P.I., 2000. The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections. The New England Journal of Medicine 342: 1930-1936.