The modulation of hepatitis C virus 1a replication by PKR is dependent on NF-kB mediated interferon beta response in Huh7.5.1 cells

Virology

Volumn 438, Issue 1, 2013, Pages 28-36

  Zhang, Lumin ^a   Alter, Harvey J ^a   Wang, Haiping ^c   Jia, Shuaizheng ^c   Wang, Ena ^a,b   Marincola, Francesco M ^a,b   Shih, James W K ^d   Wang, Richard Y ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^d XIAMEN UNIVERSITY   (China)

Author keywords

HCV1a replication; IFN ; NF kB activation; PKR silencing

Indexed keywords

BETA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE R; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; STAT1 PROTEIN;

ARTICLE; CELL STRAIN; CELL STRAIN HUH7.5.1; CONTROLLED STUDY; CYTOKINE RESPONSE; DISEASE PREDISPOSITION; ENZYME ACTIVATION; ENZYME INHIBITION; GENE REPRESSION; GENE SILENCING; HEPATITIS C; HEPATITIS C VIRUS; HEPATITIS C VIRUS 1A; HEPATITIS C VIRUS 1A INFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; VIRUS REPLICATION;

CELL LINE; EIF-2 KINASE; GENE SILENCING; HEPACIVIRUS; HEPATOCYTES; HOST-PATHOGEN INTERACTIONS; HUMANS; INTERFERON-BETA; NF-KAPPA B; VIRUS REPLICATION;

HEPATITIS C VIRUS; HEPATITIS C VIRUS GENOTYPE 1;

EID: 84875269202     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2013.01.015     Document Type: Article

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